Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Protein FAM19A1

Gene

Fam19a1

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Protein FAM19A1
Alternative name(s):
Chemokine-like protein TAFA-1
Gene namesi
Name:Fam19a1
Synonyms:Tafa1
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589 Componenti: Chromosome 6

Organism-specific databases

MGIiMGI:2443695. Fam19a1.

Subcellular locationi

  1. Secreted By similarity

GO - Cellular componenti

  1. endoplasmic reticulum Source: MGI
  2. extracellular region Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 1919Sequence AnalysisAdd
BLAST
Chaini20 – 133114Protein FAM19A1PRO_0000042722Add
BLAST

Proteomic databases

PaxDbiQ7TPG8.
PRIDEiQ7TPG8.

PTM databases

PhosphoSiteiQ7TPG8.

Expressioni

Gene expression databases

BgeeiQ7TPG8.
GenevestigatoriQ7TPG8.

Family & Domainsi

Sequence similaritiesi

Belongs to the FAM19/TAFA family.Curated

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiNOG42910.
GeneTreeiENSGT00390000001768.
HOGENOMiHOG000236302.
HOVERGENiHBG081496.
InParanoidiQ7TPG8.
OMAiWILYLWI.
OrthoDBiEOG7JDR0R.
PhylomeDBiQ7TPG8.
TreeFamiTF331749.

Family and domain databases

InterProiIPR020350. Chemokine-like_FAM19A2.
[Graphical view]
PfamiPF12020. TAFA. 1 hit.
[Graphical view]
ProDomiPD298472. Chemokine-like_2FAM19A2. 1 hit.
[Graphical view] [Entries sharing at least one domain]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q7TPG8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAMVSAMSWA LYLWISACAM LLCHGSLQHT FQQHHLHRPE GGTCEVIAAH
60 70 80 90 100
RCCNKNRIEE RSQTVKCSCL PGKVAGTTRN RPSCVDASIV IGKWWCEMEP
110 120 130
CLEGEECKTL PDNSGWMCAT GNKIKTTRIH PRT
Length:133
Mass (Da):14,873
Last modified:October 1, 2003 - v1
Checksum:iC5C20C764F8E7386
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY325120 mRNA. Translation: AAP92412.1.
BC132179 mRNA. Translation: AAI32180.1.
BC132181 mRNA. Translation: AAI32182.1.
CCDSiCCDS39574.1.
RefSeqiNP_877960.1. NM_182808.3.
UniGeneiMm.489890.

Genome annotation databases

EnsembliENSMUST00000075080; ENSMUSP00000074589; ENSMUSG00000059187.
ENSMUST00000122120; ENSMUSP00000113152; ENSMUSG00000059187.
GeneIDi320265.
KEGGimmu:320265.
UCSCiuc009dae.2. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY325120 mRNA. Translation: AAP92412.1.
BC132179 mRNA. Translation: AAI32180.1.
BC132181 mRNA. Translation: AAI32182.1.
CCDSiCCDS39574.1.
RefSeqiNP_877960.1. NM_182808.3.
UniGeneiMm.489890.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

PTM databases

PhosphoSiteiQ7TPG8.

Proteomic databases

PaxDbiQ7TPG8.
PRIDEiQ7TPG8.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000075080; ENSMUSP00000074589; ENSMUSG00000059187.
ENSMUST00000122120; ENSMUSP00000113152; ENSMUSG00000059187.
GeneIDi320265.
KEGGimmu:320265.
UCSCiuc009dae.2. mouse.

Organism-specific databases

CTDi407738.
MGIiMGI:2443695. Fam19a1.

Phylogenomic databases

eggNOGiNOG42910.
GeneTreeiENSGT00390000001768.
HOGENOMiHOG000236302.
HOVERGENiHBG081496.
InParanoidiQ7TPG8.
OMAiWILYLWI.
OrthoDBiEOG7JDR0R.
PhylomeDBiQ7TPG8.
TreeFamiTF331749.

Miscellaneous databases

ChiTaRSiFam19a1. mouse.
NextBioi396387.
PROiQ7TPG8.
SOURCEiSearch...

Gene expression databases

BgeeiQ7TPG8.
GenevestigatoriQ7TPG8.

Family and domain databases

InterProiIPR020350. Chemokine-like_FAM19A2.
[Graphical view]
PfamiPF12020. TAFA. 1 hit.
[Graphical view]
ProDomiPD298472. Chemokine-like_2FAM19A2. 1 hit.
[Graphical view] [Entries sharing at least one domain]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "TAFA: a novel secreted family with conserved cysteine residues and restricted expression in the brain."
    Tom Tang Y., Emtage P., Funk W.D., Hu T., Arterburn M., Park E.E., Rupp F.
    Genomics 83:727-734(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].
    Strain: C57BL/6J.
  2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Brain.

Entry informationi

Entry nameiF19A1_MOUSE
AccessioniPrimary (citable) accession number: Q7TPG8
Secondary accession number(s): A2RSN6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 8, 2005
Last sequence update: October 1, 2003
Last modified: February 4, 2015
This is version 65 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.