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Q7TMS1

- Q7TMS1_MOUSE

UniProt

Q7TMS1 - Q7TMS1_MOUSE

Protein
Submitted name:

Ccl2 protein

Gene

Ccl2

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 5 out of 5- Experimental evidence at transcript leveli
  1. Functioni

    GO - Molecular functioni

    1. G-protein coupled receptor binding Source: MGI
    2. heparin binding Source: Ensembl
    3. protein binding Source: MGI

    GO - Biological processi

    1. aging Source: Ensembl
    2. astrocyte cell migration Source: Ensembl
    3. cellular calcium ion homeostasis Source: Ensembl
    4. cellular response to fibroblast growth factor stimulus Source: Ensembl
    5. cellular response to organic cyclic compound Source: Ensembl
    6. chemokine-mediated signaling pathway Source: Ensembl
    7. cytoskeleton organization Source: Ensembl
    8. immune response Source: InterPro
    9. inflammatory response Source: Ensembl
    10. lipopolysaccharide-mediated signaling pathway Source: Ensembl
    11. lymphocyte chemotaxis Source: Ensembl
    12. macrophage chemotaxis Source: Ensembl
    13. MAPK cascade Source: Ensembl
    14. maternal process involved in parturition Source: Ensembl
    15. monocyte chemotaxis Source: Ensembl
    16. negative regulation of glial cell apoptotic process Source: Ensembl
    17. negative regulation of natural killer cell chemotaxis Source: Ensembl
    18. negative regulation of neuron apoptotic process Source: Ensembl
    19. neutrophil chemotaxis Source: Ensembl
    20. organ regeneration Source: Ensembl
    21. positive regulation of endothelial cell proliferation Source: Ensembl
    22. positive regulation of synaptic transmission Source: Ensembl
    23. protein kinase B signaling Source: Ensembl
    24. regulation of cell shape Source: Ensembl
    25. response to activity Source: Ensembl
    26. response to amino acid Source: Ensembl
    27. response to antibiotic Source: Ensembl
    28. response to drug Source: Ensembl
    29. response to ethanol Source: Ensembl
    30. response to gamma radiation Source: Ensembl
    31. response to glucocorticoid Source: Ensembl
    32. response to heat Source: Ensembl
    33. response to hypoxia Source: Ensembl
    34. response to mechanical stimulus Source: Ensembl
    35. response to progesterone Source: Ensembl
    36. response to vitamin B3 Source: Ensembl
    37. response to wounding Source: MGI
    38. transforming growth factor beta receptor signaling pathway Source: Ensembl
    39. vascular endothelial growth factor receptor signaling pathway Source: Ensembl

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Ccl2 proteinImported
    Gene namesi
    Name:Ccl2Imported
    OrganismiMus musculus (Mouse)Imported
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

    Organism-specific databases

    MGIiMGI:98259. Ccl2.

    Subcellular locationi

    GO - Cellular componenti

    1. cytoplasm Source: Ensembl
    2. extracellular space Source: MGI
    3. neuronal cell body Source: Ensembl

    Expressioni

    Gene expression databases

    ArrayExpressiQ7TMS1.
    BgeeiQ7TMS1.
    GenevestigatoriQ7TMS1.

    Structurei

    3D structure databases

    ProteinModelPortaliQ7TMS1.
    SMRiQ7TMS1. Positions 24-65.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Phylogenomic databases

    HOVERGENiHBG017871.
    InParanoidiQ7TMS1.

    Family and domain databases

    InterProiIPR001811. Chemokine_IL8-like_dom.
    [Graphical view]
    PfamiPF00048. IL8. 1 hit.
    [Graphical view]
    SMARTiSM00199. SCY. 1 hit.
    [Graphical view]
    SUPFAMiSSF54117. SSF54117. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q7TMS1-1 [UniParc]FASTAAdd to Basket

    « Hide

    MQVPVMLLGL LFTVAGWSIH VLAQPDAVNA PLTCCYSFTS KMIPMSRLES   50
    YKRITSSRCP KEAVV 65
    Length:65
    Mass (Da):7,188
    Last modified:October 1, 2003 - v1
    Checksum:i9FB7F1460A424B80
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BC055070 mRNA. Translation: AAH55070.1.
    UniGeneiMm.290320.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BC055070 mRNA. Translation: AAH55070.1 .
    UniGenei Mm.290320.

    3D structure databases

    ProteinModelPortali Q7TMS1.
    SMRi Q7TMS1. Positions 24-65.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Organism-specific databases

    MGIi MGI:98259. Ccl2.

    Phylogenomic databases

    HOVERGENi HBG017871.
    InParanoidi Q7TMS1.

    Miscellaneous databases

    SOURCEi Search...

    Gene expression databases

    ArrayExpressi Q7TMS1.
    Bgeei Q7TMS1.
    Genevestigatori Q7TMS1.

    Family and domain databases

    InterProi IPR001811. Chemokine_IL8-like_dom.
    [Graphical view ]
    Pfami PF00048. IL8. 1 hit.
    [Graphical view ]
    SMARTi SM00199. SCY. 1 hit.
    [Graphical view ]
    SUPFAMi SSF54117. SSF54117. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.
      , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Strain: C3H/HeImported.
      Tissue: Mesenchymal Stem CellImported.

    Entry informationi

    Entry nameiQ7TMS1_MOUSE
    AccessioniPrimary (citable) accession number: Q7TMS1
    Entry historyi
    Integrated into UniProtKB/TrEMBL: October 1, 2003
    Last sequence update: October 1, 2003
    Last modified: October 1, 2014
    This is version 66 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)