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Q7TMS1

- Q7TMS1_MOUSE

UniProt

Q7TMS1 - Q7TMS1_MOUSE

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Protein
Submitted name: Ccl2 protein
Gene
Ccl2
Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 5 out of 5 - Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. G-protein coupled receptor binding Source: MGI
  2. heparin binding Source: Ensembl
  3. protein binding Source: MGI

GO - Biological processi

  1. MAPK cascade Source: Ensembl
  2. aging Source: Ensembl
  3. astrocyte cell migration Source: Ensembl
  4. cellular calcium ion homeostasis Source: Ensembl
  5. cellular response to fibroblast growth factor stimulus Source: Ensembl
  6. cellular response to organic cyclic compound Source: Ensembl
  7. chemokine-mediated signaling pathway Source: Ensembl
  8. cytoskeleton organization Source: Ensembl
  9. immune response Source: InterPro
  10. inflammatory response Source: Ensembl
  11. lipopolysaccharide-mediated signaling pathway Source: Ensembl
  12. lymphocyte chemotaxis Source: Ensembl
  13. macrophage chemotaxis Source: Ensembl
  14. maternal process involved in parturition Source: Ensembl
  15. monocyte chemotaxis Source: Ensembl
  16. negative regulation of glial cell apoptotic process Source: Ensembl
  17. negative regulation of natural killer cell chemotaxis Source: Ensembl
  18. negative regulation of neuron apoptotic process Source: Ensembl
  19. neutrophil chemotaxis Source: Ensembl
  20. organ regeneration Source: Ensembl
  21. positive regulation of endothelial cell proliferation Source: Ensembl
  22. positive regulation of synaptic transmission Source: Ensembl
  23. protein kinase B signaling Source: Ensembl
  24. regulation of cell shape Source: Ensembl
  25. response to activity Source: Ensembl
  26. response to amino acid Source: Ensembl
  27. response to antibiotic Source: Ensembl
  28. response to drug Source: Ensembl
  29. response to ethanol Source: Ensembl
  30. response to gamma radiation Source: Ensembl
  31. response to glucocorticoid Source: Ensembl
  32. response to heat Source: Ensembl
  33. response to hypoxia Source: Ensembl
  34. response to mechanical stimulus Source: Ensembl
  35. response to progesterone Source: Ensembl
  36. response to vitamin B3 Source: Ensembl
  37. response to wounding Source: MGI
  38. transforming growth factor beta receptor signaling pathway Source: Ensembl
  39. vascular endothelial growth factor receptor signaling pathway Source: Ensembl
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Ccl2 proteinImported
Gene namesi
Name:Ccl2Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:98259. Ccl2.

Subcellular locationi

GO - Cellular componenti

  1. cytoplasm Source: Ensembl
  2. extracellular space Source: MGI
  3. neuronal cell body Source: Ensembl
Complete GO annotation...

Expressioni

Gene expression databases

ArrayExpressiQ7TMS1.
BgeeiQ7TMS1.
GenevestigatoriQ7TMS1.

Structurei

3D structure databases

ProteinModelPortaliQ7TMS1.
SMRiQ7TMS1. Positions 24-65.

Family & Domainsi

Phylogenomic databases

HOVERGENiHBG017871.
InParanoidiQ7TMS1.

Family and domain databases

InterProiIPR001811. Chemokine_IL8-like_dom.
[Graphical view]
PfamiPF00048. IL8. 1 hit.
[Graphical view]
SMARTiSM00199. SCY. 1 hit.
[Graphical view]
SUPFAMiSSF54117. SSF54117. 1 hit.

Sequencei

Sequence statusi: Complete.

Q7TMS1-1 [UniParc]FASTAAdd to Basket

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MQVPVMLLGL LFTVAGWSIH VLAQPDAVNA PLTCCYSFTS KMIPMSRLES   50
YKRITSSRCP KEAVV 65
Length:65
Mass (Da):7,188
Last modified:October 1, 2003 - v1
Checksum:i9FB7F1460A424B80
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BC055070 mRNA. Translation: AAH55070.1.
UniGeneiMm.290320.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BC055070 mRNA. Translation: AAH55070.1 .
UniGenei Mm.290320.

3D structure databases

ProteinModelPortali Q7TMS1.
SMRi Q7TMS1. Positions 24-65.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Organism-specific databases

MGIi MGI:98259. Ccl2.

Phylogenomic databases

HOVERGENi HBG017871.
InParanoidi Q7TMS1.

Miscellaneous databases

SOURCEi Search...

Gene expression databases

ArrayExpressi Q7TMS1.
Bgeei Q7TMS1.
Genevestigatori Q7TMS1.

Family and domain databases

InterProi IPR001811. Chemokine_IL8-like_dom.
[Graphical view ]
Pfami PF00048. IL8. 1 hit.
[Graphical view ]
SMARTi SM00199. SCY. 1 hit.
[Graphical view ]
SUPFAMi SSF54117. SSF54117. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.
    , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: C3H/HeImported.
    Tissue: Mesenchymal Stem CellImported.

Entry informationi

Entry nameiQ7TMS1_MOUSE
AccessioniPrimary (citable) accession number: Q7TMS1
Entry historyi
Integrated into UniProtKB/TrEMBL: October 1, 2003
Last sequence update: October 1, 2003
Last modified: June 11, 2014
This is version 65 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

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