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Q7TMA5

- APOB_RAT

UniProt

Q7TMA5 - APOB_RAT

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Protein
Apolipoprotein B-100
Gene
Apob, Aa1064, Ac1-060
Organism
Rattus norvegicus (Rat)
Status
Reviewed - Annotation score: 5 out of 5 - Experimental evidence at protein leveli

Functioni

Apolipoprotein B is a major protein constituent of chylomicrons (apo B-48), LDL (apo B-100) and VLDL (apo B-100). Apo B-100 functions as a recognition signal for the cellular binding and internalization of LDL particles by the apoB/E receptor.1 Publication

GO - Molecular functioni

  1. cholesterol transporter activity Source: Ensembl
  2. heparin binding Source: UniProtKB-KW
  3. lipid binding Source: RGD
  4. phospholipid binding Source: Ensembl
  5. protein binding Source: RGD

GO - Biological processi

  1. artery morphogenesis Source: Ensembl
  2. cellular response to prostaglandin stimulus Source: RGD
  3. cellular response to tumor necrosis factor Source: RGD
  4. cholesterol efflux Source: Ensembl
  5. cholesterol homeostasis Source: Ensembl
  6. cholesterol metabolic process Source: UniProtKB-KW
  7. fertilization Source: Ensembl
  8. in utero embryonic development Source: Ensembl
  9. lipid metabolic process Source: RGD
  10. lipoprotein biosynthetic process Source: Ensembl
  11. lipoprotein catabolic process Source: Ensembl
  12. lipoprotein transport Source: Ensembl
  13. low-density lipoprotein particle clearance Source: Ensembl
  14. low-density lipoprotein particle remodeling Source: Ensembl
  15. nervous system development Source: Ensembl
  16. positive regulation of cholesterol storage Source: Ensembl
  17. positive regulation of macrophage derived foam cell differentiation Source: Ensembl
  18. post-embryonic development Source: Ensembl
  19. regulation of cholesterol biosynthetic process Source: Ensembl
  20. response to carbohydrate Source: RGD
  21. response to lipopolysaccharide Source: RGD
  22. response to organic substance Source: RGD
  23. response to selenium ion Source: RGD
  24. response to virus Source: Ensembl
  25. sperm motility Source: Ensembl
  26. spermatogenesis Source: Ensembl
  27. triglyceride catabolic process Source: RGD
  28. triglyceride mobilization Source: Ensembl
Complete GO annotation...

Keywords - Biological processi

Cholesterol metabolism, Lipid metabolism, Lipid transport, Steroid metabolism, Sterol metabolism, Transport

Keywords - Ligandi

Heparin-binding

Enzyme and pathway databases

ReactomeiREACT_198722. Scavenging by Class H Receptors.
REACT_198733. Scavenging by Class A Receptors.
REACT_198734. Scavenging by Class B Receptors.
REACT_198755. Scavenging by Class F Receptors.
REACT_199015. Retinoid metabolism and transport.

Names & Taxonomyi

Protein namesi
Recommended name:
Apolipoprotein B-100
Short name:
Apo B-100
Cleaved into the following chain:
Apolipoprotein B-48
Short name:
Apo B-48
Gene namesi
Name:Apob
ORF Names:Aa1064, Ac1-060
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
ProteomesiUP000002494: Chromosome 6

Organism-specific databases

RGDi2129. Apob.

Subcellular locationi

Cytoplasm By similarity. Secreted 1 Publication

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB
  2. endoplasmic reticulum Source: Ensembl
  3. extracellular space Source: RGD
  4. intermediate-density lipoprotein particle Source: Ensembl
  5. intracellular membrane-bounded organelle Source: RGD
  6. low-density lipoprotein particle Source: UniProtKB-KW
  7. mature chylomicron Source: Ensembl
  8. very-low-density lipoprotein particle Source: RGD
  9. vesicle lumen Source: RGD
  10. vesicle membrane Source: RGD
Complete GO annotation...

Keywords - Cellular componenti

Chylomicron, Cytoplasm, LDL, Secreted, VLDL

Pathology & Biotechi

Keywords - Diseasei

Atherosclerosis

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2727 By similarity
Add
BLAST
Chaini28 – 47434716Apolipoprotein B-100
PRO_0000293536Add
BLAST
Chaini28 – 21462119Apolipoprotein B-48
PRO_0000293537Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Disulfide bondi65 ↔ 84 By similarity
Glycosylationi172 – 1721N-linked (GlcNAc...) Reviewed prediction
Disulfide bondi173 ↔ 199 By similarity
Disulfide bondi232 ↔ 248 By similarity
Disulfide bondi372 ↔ 377 By similarity
Disulfide bondi466 ↔ 501 By similarity
Disulfide bondi954 ↔ 964 By similarity
Glycosylationi971 – 9711N-linked (GlcNAc...) Reviewed prediction
Glycosylationi1336 – 13361N-linked (GlcNAc...) Reviewed prediction
Glycosylationi1345 – 13451N-linked (GlcNAc...) Reviewed prediction
Glycosylationi1491 – 14911N-linked (GlcNAc...) Reviewed prediction
Modified residuei1973 – 19731N6-acetyllysine By similarity
Glycosylationi2094 – 20941N-linked (GlcNAc...) Reviewed prediction
Glycosylationi2522 – 25221N-linked (GlcNAc...) Reviewed prediction
Glycosylationi2662 – 26621N-linked (GlcNAc...) Reviewed prediction
Glycosylationi2741 – 27411N-linked (GlcNAc...) Reviewed prediction
Glycosylationi2791 – 27911N-linked (GlcNAc...) Reviewed prediction
Glycosylationi2897 – 28971N-linked (GlcNAc...) Reviewed prediction
Glycosylationi2944 – 29441N-linked (GlcNAc...) Reviewed prediction
Glycosylationi3063 – 30631N-linked (GlcNAc...) Reviewed prediction
Glycosylationi3186 – 31861N-linked (GlcNAc...) Reviewed prediction
Glycosylationi3299 – 32991N-linked (GlcNAc...) Reviewed prediction
Glycosylationi3321 – 33211N-linked (GlcNAc...) Reviewed prediction
Glycosylationi3428 – 34281N-linked (GlcNAc...) Reviewed prediction
Glycosylationi3715 – 37151N-linked (GlcNAc...) Reviewed prediction
Glycosylationi3828 – 38281N-linked (GlcNAc...) Reviewed prediction
Glycosylationi4203 – 42031N-linked (GlcNAc...) Reviewed prediction
Glycosylationi4232 – 42321N-linked (GlcNAc...) Reviewed prediction

Post-translational modificationi

Palmitoylated; structural requirement for proper assembly of the hydrophobic core of the lipoprotein particle By similarity.

Keywords - PTMi

Acetylation, Disulfide bond, Glycoprotein, Lipoprotein, Palmitate

Proteomic databases

PaxDbiQ7TMA5.
PRIDEiQ7TMA5.

PTM databases

PhosphoSiteiQ7TMA5.

Expressioni

Tissue specificityi

Detected in intestine and liver (at protein level).1 Publication

Gene expression databases

GenevestigatoriQ7TMA5.

Interactioni

Subunit structurei

Interacts with PCSK9 By similarity.

Protein-protein interaction databases

BioGridi248449. 1 interaction.
DIPiDIP-29910N.

Structurei

3D structure databases

ProteinModelPortaliQ7TMA5.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini33 – 660628Vitellogenin
Add
BLAST

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni29 – 11385Heparin-binding By similarity
Add
BLAST
Regioni219 – 29375Heparin-binding By similarity
Add
BLAST
Regioni890 – 94758Heparin-binding By similarity
Add
BLAST
Regioni2010 – 2145136Heparin-binding By similarity
Add
BLAST
Regioni3123 – 319876Heparin-binding By similarity
Add
BLAST
Regioni3136 – 314611Basic (possible receptor binding region) By similarity
Add
BLAST
Regioni3336 – 335621LDL receptor binding By similarity
Add
BLAST
Regioni3346 – 3479134Heparin-binding By similarity
Add
BLAST
Regioni3349 – 33579Basic (possible receptor binding region) By similarity

Sequence similaritiesi

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiNOG290405.
GeneTreeiENSGT00590000083139.
HOGENOMiHOG000034000.
HOVERGENiHBG050546.
InParanoidiQ7TMA5.
KOiK14462.
OMAiHIPEFQL.
OrthoDBiEOG7VB2DG.
PhylomeDBiQ7TMA5.
TreeFamiTF331316.

Family and domain databases

Gene3Di1.10.472.10. 2 hits.
1.25.10.20. 1 hit.
2.20.50.20. 2 hits.
2.20.80.10. 1 hit.
2.30.230.10. 1 hit.
InterProiIPR022176. ApoB100_C.
IPR013763. Cyclin-like.
IPR006671. Cyclin_N.
IPR015819. Lipid_transp_b-sht_shell.
IPR001747. Lipid_transpt_N.
IPR009454. Lipid_transpt_open_b-sht.
IPR015816. Vitellinogen_b-sht_N.
IPR015255. Vitellinogen_open_b-sht.
IPR015817. Vitellinogen_open_b-sht_sub1.
IPR015818. Vitellinogen_open_b-sht_sub2.
IPR011030. Vitellinogen_superhlx.
[Graphical view]
PfamiPF12491. ApoB100_C. 1 hit.
PF00134. Cyclin_N. 1 hit.
PF06448. DUF1081. 1 hit.
PF09172. DUF1943. 1 hit.
PF01347. Vitellogenin_N. 1 hit.
[Graphical view]
SMARTiSM00385. CYCLIN. 1 hit.
SM00638. LPD_N. 1 hit.
[Graphical view]
SUPFAMiSSF47954. SSF47954. 2 hits.
SSF48431. SSF48431. 1 hit.
SSF56968. SSF56968. 2 hits.
PROSITEiPS51211. VITELLOGENIN. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q7TMA5-1 [UniParc]FASTAAdd to Basket

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MGPQRPALRA PLLLLFLLLF LDTSVWAQDA TRFKHLRKYV YSYEAESSSG     50
VRGTADSRSA TKINCKVELE VPQVCTLIMR TSQCTLKEVY GFNPEGKALM 100
KKTKNSEEFA SAMSRYELKL AFPEGKRVAL YPDLGEPNYI LNIKRGIISA 150
LLVPPETEED KQVLFQDTVY GNCSTQVTVN SRKGTVATEM STERNLQHCD 200
GFQPISTSVS PLALIKGLVR PLSTLISSSQ SCQYTLEPKR KHVSEAICNE 250
QHLFLPFSYK NKYGIMTHVT QKLSLEDTPK INSRFFRGGI NQVGLAFEST 300
KSTSPPKQAD AVLKTLQELK KLSISEQNAQ RANLFHKLVT ELRGLSGEAI 350
TSLLPQLIEV SSPITLQALI QCGQPECYTH ILQWLKTEKA HPLLIDIVTY 400
LMALIPNPSV QRLQEIFNTA KELQSRATLY ALSHAVNSYY AIMDHSRSPV 450
LEDIAGYLMK QIDNECMGDE DRTFLILRVI GNMGRTMERV MPALKSSVLN 500
CVRSTKPSLQ IQKAALQALR KMEMGDEVRT ILFDTFVNDV APVEKRLAAY 550
LLLMRSPSSS DINKIAKLLQ WEQSEQVKNF VASHIANILN SEELYVQDLK 600
NLIKNALVNS RLPTIMDFRK FSRNYQISKS VSIPLFDPVS AKIEGNLVFD 650
PSSYLPKESM LKTTLTVFGI ASLDLFEIGL EGKGFEPTLE ALFGKQGFFP 700
DSVNKALYWV NGQVPDRVSK VLVDHFGYTK DDKHEQDMVN GIMPIVDKLI 750
KELKSKEIPE ARAYLRILGK ELGFVRLQDL QVLGKLLLNG AQTFRGVPQM 800
IVQAIREGSK DDLFLHYIFM ENAFELPTGV GLQLQVSSSG VFTPGIKAGV 850
RLELANIQAE LVAKPSVSLE FVTNMGIIIP DFAKSGVQMN TNFFHESGLE 900
ARVALKAGQL KVIIPSPKRP VKLFSGSNTL HLVSTTKTEV IPPLIENRKS 950
WSTCKPFFTG MNYCTTGAYS NASSTESASY YPLTGDTRYE LELKPTGEVE 1000
QYSASATYEL LKEDKSLVDT LKFLVQAEGV QQSEATAMFK YNRRSRTLSS 1050
EVLIPGFDVN FGTILRVNDE SSKDKNTYKL ILDIQNKKIT EVSVVGHVSY 1100
DKKGDGKVKG VVSIPRLQAE ARSEVHTHWS PTKLLFQMDS SATAYGSTIS 1150
KRVAWRYDNE KIEFDWNTGT NVDTKKVASN FPVDLSRYPR MVHEYANGLL 1200
DHRVPQTDMT FRHMGSKLIV DHLNGLSELN LPKVGLPDFH IPDNLFLKTD 1250
GRVKYTLNKN RIEIDIPLPL GGKSSKDLKV PESVRTPALN FKSVGFHLPS 1300
QEVQIPTFTI PKTHQLQVPL LGILDLSTNV YSNLYNWSVS YTGGNTSRDH 1350
FSLQAQYRMK ADSVVDLFSY SVQGSGETTY DSKSTFTLSC DGSLHHKFLD 1400
SKFKVSHVEK FGNNPVSKGL LTFETSSALG PQMSATVQLD SKKKQHLYVK 1450
DIKVDGQFRV FSLYAQGEYG LSYERDSMTG QMSGESNMKF NSTYFQGTNQ 1500
IVGMYQDGML SVTSTSDLQD GIFKNTASLK YENYELTLKS DSSGQYENFA 1550
ASNKLDMTFS KQSALLRSEH QANYKSLRLV TLLSGSLTSQ GVELNADILG 1600
TDKINTGAHK STLKIAQDGV STSATTNLKY SPLLLENELN AELGLSGASM 1650
KLSTSGRFKE HHAKFSLDGR AALTEVSLGS IYQAMILGAD SKNVFNFKLS 1700
REGLKLSNDM MGSYAEMKLD HTHSLRISGL SLDFFSKMDN IYSGDKFYKQ 1750
NFNLQLQPYS FGITLSNDLK YDALVLTNNG RLRLEPLKLN VGGNFKGTYQ 1800
NNELKHIYTI SYTDLVVASY RADTVATVQG VEFSHRLNAD IEGLASSVDV 1850
TTSYSSDPLH FNNVFRFVLA PFTLGVDTHT SGDGKMSLWG EHTGQMYSKF 1900
LLKAEPLALT FSHDYKGSTS HNLLYKNSVS TALEHTLSAL LTPAEQTSSW 1950
KFKTSLNDKV YSQEFEAYNT KDKIGIELSG RADLSGLYSP IKVPFFYSEP 2000
VNVLNSLEIN DAFDEPREFT IDAVVKYDKN QDVHTISLPF FQSLPDYLER 2050
NRRGIISLLE AMKGELQRLS VDQFVRKYRV ALSRLPQQIH DYLNASDWER 2100
QVAGAKEKLT SFMENYRITD NDVLIALDSA KINLNEKLSQ LETYAIQFDQ 2150
YIRDNYDAQD LKRTIAQIID RIIEKLKMLD EQYHIRVNLA KSIHNLYLFV 2200
ENVDLNQISS SGASWIQNVD TKYQIRIQIQ EKLQHLRTQI HNIDIQQLAA 2250
ELKQQIEALD VPMHLDQLRT AILFQRISVI IERVKYFVMN LIEDFKVTEK 2300
INTFRVIVRE LIEKYEVDRQ IQVLMDKSIE LAHRYSLSEP LQKLSNVLQQ 2350
IEIKDYYDKL VGFIDDTVEW IKAVSFKNII EELNRLIDMS VKKLKAFDYH 2400
QFVDKTNSKI REMTQRINAE IQALELPQKT EALKLWVEDF KTTVSNSLEK 2450
LKDTKVTVVV DWLQDGLAQI KAQFQDALED VRDRIYQMDI QGELERCLSL 2500
VSQVYSTVVT YISDWWTLTA KNITDFAEQY STQKWAESVK ALVEQGFIVP 2550
EIQTFLGTMP AFEVSLHALQ EANFQTPDFI VPLTDLRIPS IWINFKMLKN 2600
VKIPLRFSTP EFTLLNTFRV RSFTIDLLEI KAKIIRTIDQ MLSSELQWPL 2650
PEVYLRDLEM VNISLARLSL PDFHVPEITI PEFTIPNVNL KDLQVPDLHI 2700
PEFQLPHLSC TTEIPAFGKL HSVLKIQSPL FILDASANIQ NITTSENKAE 2750
IVASVTARGE SKFEALNFDF QAQAQFLELN ANPLVLKESV NFSSKHVRME 2800
HEGKILVSGK ALEGKSDTVA RLHTEKNTVE FNNGIVVKIN NQFTLDSQTK 2850
YFHKLSVPRL DFSSKASLNN EIKTLLEAGH MAWTSSGTGS WNWACPNFSD 2900
EGIHSSKISF IVDGPIASFG LSNNINGKHL RVVQKLTSES GFLNYSRFEV 2950
ESKVESQHVG SSILTAEGRA LLGDAKAEMT GEHNANLNGK VIGTLKNSLF 3000
FSAQPFEITA STNNEGNLKV SFPLKLTGKI DFLNNYALFL SPHAQQASWQ 3050
LSTRFNQYKY NQNFSAINNE HNMEASIVMN GDANLDFLNI PLTIPEINLP 3100
YTRFTTPLLK DFSIWEETGL KEFLKTTKQS FDLSIKAQYK KNRDKHSVVI 3150
PLKMFYEFML NNVNSWDRKF EKVRDNALHF LTASYNETKI KFDKYKTENS 3200
LNQPSRTFQN RGHTIPVLNI EVSPFAVETL ASSHVIPKAI RTPSVTIPGP 3250
NIIVPSYRLV LPSLQLPVFH IPRTLFKFSL PDFKKLSTID NIYIPAMGNF 3300
TYDFSFKSSV ITLNTNAGLY NQSDLVARFL SSSSFVTDAL QYKLEGTSRL 3350
MRKKVLKLAT AVSLTNKFLK GSHDSTISLT KKNMEASVKT TANLHAPIFT 3400
MNFKQELNGN TKSKPTVSSS IELNYDFNSS KLHSAAKGGV DHKFSLESLT 3450
SYLSIESFTK GNIKGSFLSQ EYSGSVANEA NVYLNSKGTR SSVRLQGASN 3500
FAGIWNFEVG ENFAGEATLR RIYGTWEHNM INHLQVFSYF DTKGKQTCRA 3550
TLELSPWTMS TLLQVHVSQP SPLFDLHHFD QEVILKASTK NQKVSWKSEV 3600
QVESQVLQHN AHFSNDQEEV RLDIAGSLEG QLWDLENFFL PAFGKSLREL 3650
LQIDGKRQYL QASTSLHYTK NPNGYLLSLP VQELTDRFII PGLKLNDFSG 3700
IKIYKKLSTS PFALNLTMLP KVKFPGVDLL TQYSKPEGSS VPTFETTIPE 3750
IQLTVSQFTL PKSFPVGNTV FDLNKLTNLI ADVDLPSITL PEQTIEIPSL 3800
EFSVPAGIFI PFFGELTAHV GMASPLYNVT WSTGWKNKAD HVETFLDSTC 3850
SSTLQFLEYA LKVVGTHRIE NDKFIYKIKG TLQHCDFNVK YNEDGIFEGL 3900
WDLEGEAHLD ITSPALTDFH LHYKEDKTSV SASAASPAIG TVSLDASTDD 3950
QSVRLNVYFR PQSPPDNKLS IFKMEWRDKE SDGETYIKIN WEEEAAFRLL 4000
DSLKSNVPKA SEAVYDYVKK YHLGHASSEL RKSLQNDAEH AIRMVDEMNV 4050
NAQRVTRDTY QSLYKKMLAQ ESQSIPEKLK KMVLGSLVRI TQKYHMAVTW 4100
LMDSVIHFLK FNRVQFPGNA GTYTVDELYT IAMRETKKLL SQLFNGLGHL 4150
FSYVQDQVEK SRVINDITFK CPFSPTPCKL KDVLLIFRED LNILSNLGQQ 4200
DINFTTILSD FQSFLERLLD IIEEKIECLK NNESTCVPDH INMFFKTHIP 4250
FAFKSLRENI YSVFSEFNDF VQSILQEGSY KLQQVHQYMK AFREEYFDPS 4300
VVGWTVKYYE IEEKMVDLIK TLLAPLRDFY SEYSVTAADF ASKMSTQVEQ 4350
FVSRDIREYL SMLADINGKG REKVAELSIV VKERIKSWST AVAEITSDYL 4400
RQLHSKLQDF SDQLSGYYEK FVAESTRLID LSIQNYHMFL RYIAELLKKL 4450
QVATANNGLL KRGDFEAAVK LGIACLYNEG LSVSDEAYAE VNGLKASRFF 4500
SMDERLNMGS DPFIWLSICP PCFRKLRDFA GKGCWEAQPA LAKDCAGGSQ 4550
LGLEGKAFSE SVCQLFQASQ AVNKQQIFSV QKGLSDTVRY ILIGWLVEVA 4600
PMKDFTSLCL HLTVECVGRY LQRKLVPRYK LQLLGIACMV ICTWFISKEI 4650
LTIREAVRLT DNTYKYKDLV RVKREIISAL EGKIRIPTVV DYKEVLLTLV 4700
PVTPRTQYLC SFLCELTLSV YTPAHLASAA LLLARLMHGQ TQP 4743
Length:4,743
Mass (Da):536,024
Last modified:October 1, 2003 - v1
Checksum:iB01AD103F8EC5320
GO

RNA editingi

The stop codon (UAA) at position 2147 is created by RNA editing. Apo B-48, derived from the fully edited RNA, is produced only in the intestine and is found in chylomicrons. Apo B-48 is a shortened form of apo B-100 which lacks the LDL-receptor region. The unedited version (apo B-100) is produced by the liver and is found in the VLDL and LDL.1 Publication

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AY318958 mRNA. Translation: AAP85369.1.
AY321317 mRNA. Translation: AAP86249.1.
RefSeqiNP_062160.2. NM_019287.2.
UniGeneiRn.33815.

Genome annotation databases

EnsembliENSRNOT00000046811; ENSRNOP00000039779; ENSRNOG00000005542.
GeneIDi54225.
KEGGirno:54225.

Keywords - Coding sequence diversityi

RNA editing

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AY318958 mRNA. Translation: AAP85369.1 .
AY321317 mRNA. Translation: AAP86249.1 .
RefSeqi NP_062160.2. NM_019287.2.
UniGenei Rn.33815.

3D structure databases

ProteinModelPortali Q7TMA5.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 248449. 1 interaction.
DIPi DIP-29910N.

PTM databases

PhosphoSitei Q7TMA5.

Proteomic databases

PaxDbi Q7TMA5.
PRIDEi Q7TMA5.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSRNOT00000046811 ; ENSRNOP00000039779 ; ENSRNOG00000005542 .
GeneIDi 54225.
KEGGi rno:54225.

Organism-specific databases

CTDi 338.
RGDi 2129. Apob.

Phylogenomic databases

eggNOGi NOG290405.
GeneTreei ENSGT00590000083139.
HOGENOMi HOG000034000.
HOVERGENi HBG050546.
InParanoidi Q7TMA5.
KOi K14462.
OMAi HIPEFQL.
OrthoDBi EOG7VB2DG.
PhylomeDBi Q7TMA5.
TreeFami TF331316.

Enzyme and pathway databases

Reactomei REACT_198722. Scavenging by Class H Receptors.
REACT_198733. Scavenging by Class A Receptors.
REACT_198734. Scavenging by Class B Receptors.
REACT_198755. Scavenging by Class F Receptors.
REACT_199015. Retinoid metabolism and transport.

Miscellaneous databases

NextBioi 610644.
PROi Q7TMA5.

Gene expression databases

Genevestigatori Q7TMA5.

Family and domain databases

Gene3Di 1.10.472.10. 2 hits.
1.25.10.20. 1 hit.
2.20.50.20. 2 hits.
2.20.80.10. 1 hit.
2.30.230.10. 1 hit.
InterProi IPR022176. ApoB100_C.
IPR013763. Cyclin-like.
IPR006671. Cyclin_N.
IPR015819. Lipid_transp_b-sht_shell.
IPR001747. Lipid_transpt_N.
IPR009454. Lipid_transpt_open_b-sht.
IPR015816. Vitellinogen_b-sht_N.
IPR015255. Vitellinogen_open_b-sht.
IPR015817. Vitellinogen_open_b-sht_sub1.
IPR015818. Vitellinogen_open_b-sht_sub2.
IPR011030. Vitellinogen_superhlx.
[Graphical view ]
Pfami PF12491. ApoB100_C. 1 hit.
PF00134. Cyclin_N. 1 hit.
PF06448. DUF1081. 1 hit.
PF09172. DUF1943. 1 hit.
PF01347. Vitellogenin_N. 1 hit.
[Graphical view ]
SMARTi SM00385. CYCLIN. 1 hit.
SM00638. LPD_N. 1 hit.
[Graphical view ]
SUPFAMi SSF47954. SSF47954. 2 hits.
SSF48431. SSF48431. 1 hit.
SSF56968. SSF56968. 2 hits.
PROSITEi PS51211. VITELLOGENIN. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Liver regeneration after PH."
    Xu C.S., Li W.Q., Li Y.C., Wang G.P., Chai L.Q., Yuan J.Y., Yang K.J., Yan H.M., Chang C.F., Zhao L.F., Ma H., Wang L., Wang S.F., Han H.P., Shi J.B., Rahman S., Wang Q.N., Zhang J.B.
    Submitted (JUN-2003) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Liver.
  2. "Identification of circulating apolipoproteins synthesized by rat small intestine in vivo."
    Wu A.L., Windmueller H.G.
    J. Biol. Chem. 253:2525-2528(1978) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION, TISSUE SPECIFICITY, SUBCELLULAR LOCATION.
  3. "Apolipoprotein B (B-48) of rat chylomicrons is not a precursor of the apolipoprotein of low density lipoproteins."
    Van't Hooft F.M., Hardman D.A., Kane J.P., Havel R.J.
    Proc. Natl. Acad. Sci. U.S.A. 79:179-182(1982) [PubMed] [Europe PMC] [Abstract]
    Cited for: CHARACTERIZATION.
  4. "Expression of apolipoprotein B mRNAs encoding higher- and lower-molecular weight isoproteins in rat liver and intestine."
    Tennyson G.E., Sabatos C.A., Higuchi K., Meglin N., Brewer H.B. Jr.
    Proc. Natl. Acad. Sci. U.S.A. 86:500-504(1989) [PubMed] [Europe PMC] [Abstract]
    Cited for: RNA EDITING.

Entry informationi

Entry nameiAPOB_RAT
AccessioniPrimary (citable) accession number: Q7TMA5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 10, 2007
Last sequence update: October 1, 2003
Last modified: September 3, 2014
This is version 84 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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