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Protein

Putative serine/threonine-protein kinase/receptor R826

Gene

MIMI_R826

Organism
Acanthamoeba polyphaga mimivirus (APMV)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + a protein = ADP + a phosphoprotein.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei813ATPPROSITE-ProRule annotation1
Active sitei909Proton acceptorBy similarity1
Binding sitei1426ATPPROSITE-ProRule annotation1
Active sitei1522Proton acceptorBy similarity1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi792 – 800ATPPROSITE-ProRule annotation9
Nucleotide bindingi1405 – 1413ATPPROSITE-ProRule annotation9

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionKinase, Receptor, Serine/threonine-protein kinase, Transferase
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Putative serine/threonine-protein kinase/receptor R826 (EC:2.7.11.1)
Gene namesi
Ordered Locus Names:MIMI_R826
OrganismiAcanthamoeba polyphaga mimivirus (APMV)
Taxonomic identifieri212035 [NCBI]
Taxonomic lineageiVirusesdsDNA viruses, no RNA stageMimiviridaeMimivirus
Virus hostiAcanthamoeba polyphaga (Amoeba) [TaxID: 5757]
Proteomesi
  • UP000001134 Componenti: Genome

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei742 – 762HelicalSequence analysisAdd BLAST21

GO - Cellular componenti

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 23Sequence analysisAdd BLAST23
ChainiPRO_000025399724 – 1657Putative serine/threonine-protein kinase/receptor R826Add BLAST1634

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi153N-linked (GlcNAc...) asparagine; by hostSequence analysis1
Glycosylationi178N-linked (GlcNAc...) asparagine; by hostSequence analysis1
Glycosylationi238N-linked (GlcNAc...) asparagine; by hostSequence analysis1
Glycosylationi255N-linked (GlcNAc...) asparagine; by hostSequence analysis1
Glycosylationi352N-linked (GlcNAc...) asparagine; by hostSequence analysis1
Glycosylationi454N-linked (GlcNAc...) asparagine; by hostSequence analysis1
Glycosylationi476N-linked (GlcNAc...) asparagine; by hostSequence analysis1
Glycosylationi494N-linked (GlcNAc...) asparagine; by hostSequence analysis1
Glycosylationi596N-linked (GlcNAc...) asparagine; by hostSequence analysis1

Keywords - PTMi

Glycoprotein

Structurei

3D structure databases

ProteinModelPortaliQ7T6X2
SMRiQ7T6X2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini786 – 1049Protein kinase 1PROSITE-ProRule annotationAdd BLAST264
Domaini1134 – 1277Guanylate cyclasePROSITE-ProRule annotationAdd BLAST144
Domaini1399 – 1651Protein kinase 2PROSITE-ProRule annotationAdd BLAST253

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi1058 – 1065Poly-Ser8

Keywords - Domaini

Repeat, Signal, Transmembrane, Transmembrane helix

Phylogenomic databases

OrthoDBiVOG090000KG

Family and domain databases

Gene3Di3.30.70.1230, 1 hit
InterProiView protein in InterPro
IPR001054 A/G_cyclase
IPR011009 Kinase-like_dom_sf
IPR029787 Nucleotide_cyclase
IPR024370 PBP_domain
IPR000719 Prot_kinase_dom
IPR017441 Protein_kinase_ATP_BS
IPR001245 Ser-Thr/Tyr_kinase_cat_dom
IPR008271 Ser/Thr_kinase_AS
PfamiView protein in Pfam
PF00211 Guanylate_cyc, 1 hit
PF12849 PBP_like_2, 2 hits
PF07714 Pkinase_Tyr, 2 hits
PRINTSiPR00109 TYRKINASE
SMARTiView protein in SMART
SM00044 CYCc, 1 hit
SM00220 S_TKc, 2 hits
SUPFAMiSSF55073 SSF55073, 1 hit
SSF56112 SSF56112, 2 hits
PROSITEiView protein in PROSITE
PS50125 GUANYLATE_CYCLASE_2, 1 hit
PS00107 PROTEIN_KINASE_ATP, 2 hits
PS50011 PROTEIN_KINASE_DOM, 2 hits
PS00108 PROTEIN_KINASE_ST, 2 hits

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q7T6X2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRLNSQIVFC IVVVISCLSM IECKMGSRIY CSGSLSSVEL FSQYISNYAL
60 70 80 90 100
RNDDVTIIYA GMSVDEINAD VYIADCSAYD RAIPQIYMIS YGLIQFPIVG
110 120 130 140 150
QAIVIIYNVP GLSSHNMIID RETLGRIWTG NIRKWNDIQI QNLNPDIASQ
160 170 180 190 200
LPNETITLGY NDAYYLSISE IMQLALRNFS EEFANAHTIA GGKFGNMIPA
210 220 230 240 250
KQGYAIDAGE ASESRIDWVK NTPFSLSFAD FATVYPRNVS YMHMYNKAGK
260 270 280 290 300
LVEPNITTVQ SAMADFKEIY TTNDFTIDIF DASGENSWPI SWVNYISMTS
310 320 330 340 350
TFQQADCIRT KELLDFIAWF YMNNEIAEII KEYQYYPLDN TIKKIAIDNM
360 370 380 390 400
YNVTCNGKVS QEHQYLIAFG SPLSIMASWP NTWASSMTTV KYYASLSDQA
410 420 430 440 450
IELQKTFSGD FGITIKDFDK NKYLSSTMED IGVSHLAAFN IVPAYNIPEF
460 470 480 490 500
IGLNETLVLN YETIVDIYLG LVTNWNDSSI RNSNNPYINS LLPNKTITVV
510 520 530 540 550
VQKVESDVNE LFTNFLSCKS DKFNNAIGPT NLPEFDFVSN NVVYTEDVYG
560 570 580 590 600
VGNTLVSTDY SFAFWPEPGI RLLSHMAIVQ AASIQTSTGT IIKPTNETLS
610 620 630 640 650
KAVDNKINSI NRRDIEDGSW PFIAMMSLVY HQKTMQSFSK ASALADFIYW
660 670 680 690 700
TQFDDTAASI ADTQGYYVAS IHPTILRENL ELLQSFTFED RTVSKVANCI
710 720 730 740 750
FEGTICYNKG TCNNNVCLCN IDREGQFCEL EKTQSDTNIV TIILAVVIPI
760 770 780 790 800
AFIIVCIICI LVVALIFSLR FRKGISDDWE IDFHELELGE QLGTGAFGEV
810 820 830 840 850
HKGTWRGTEV AVKMISPDKT ITKDIERNFK DEVRVMTTLR HPNVVLFMAA
860 870 880 890 900
STKPPKMCIV MEFMALGSLH DLLKNELIPD IPFALKVKIA YQASKGMHFL
910 920 930 940 950
HSSGITHRDL KSLNLLLDIK WNVKVSDFGL TKFKSDVKSI NPEKFAGTIQ
960 970 980 990 1000
WTAPEILSED REVDYILSDV YSFGIIMWEL ITRDQPYFGM SPAAIAVSVI
1010 1020 1030 1040 1050
RDNYRPVISD QLRSEVAPEY IELLTSCWHF DPTIRPTFLE IMTRLSNLMG
1060 1070 1080 1090 1100
DSGMTGMSSS SSNSSKFDYN SFGKVQQFAI NRTDPDGIVQ NSYNRTDSYD
1110 1120 1130 1140 1150
LGSNNSHSSI TSDTNKSNKY LRQTNIQHPT GEVVVVFTDI ISAAQLWEFD
1160 1170 1180 1190 1200
ASEMKNATIL YNKLVRSICN ECGGYESLIS KERNSGEGSF CLIFSDVQNA
1210 1220 1230 1240 1250
ITFCEELQKQ LVGVNWSPKL LEHPITAIEK DINGTIIYAG LRVRIGLHFG
1260 1270 1280 1290 1300
STKINYDPIS RKYEYIGPTV TTAAAVTTIT HGGQIIMTED VANKLSTENS
1310 1320 1330 1340 1350
NKPVCLGRVD IDGIPDSLVL YEYVISALIG RFFGGVTRKN ASFVSNETST
1360 1370 1380 1390 1400
DYDDMDTDNS TFSARVPHQA YQYHAAIENN ERYLTSAGLC SWVINYDEIK
1410 1420 1430 1440 1450
MGEQIGLGSY GVVYRGKWKN VDVAIKKFIK QKIDENHLLG IREEIAFLKK
1460 1470 1480 1490 1500
LHHPNIITMV GASLKKPNIC IVTEYMAKGN LRDAMRTCTP KLEWHQKIKI
1510 1520 1530 1540 1550
LVNIAKGISY LHSFDPPIIH RDIKPSNILI DENWNVKIAD FGFARIKEEN
1560 1570 1580 1590 1600
AIMTRCGTPC WTAPEIIRND IYDEKVDVFS FGIVMWEVLT CKEPFIGANF
1610 1620 1630 1640 1650
MKITMDILED VRPKIPQDCP EEFAKLMRKC WHAKSTKRPT MDDVIIVLAK

FCPDISV
Length:1,657
Mass (Da):186,740
Last modified:December 7, 2004 - v2
Checksum:iC43B8AA183A18312
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY653733 Genomic DNA Translation: AAQ09588.2
RefSeqiYP_003987358.1, NC_014649.1

Genome annotation databases

GeneIDi9925489
KEGGivg:9925489

Similar proteinsi

Entry informationi

Entry nameiYR826_MIMIV
AccessioniPrimary (citable) accession number: Q7T6X2
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 17, 2006
Last sequence update: December 7, 2004
Last modified: April 25, 2018
This is version 92 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health