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Protein

Glycerol-3-phosphate dehydrogenase [NAD(+)]

Gene

gpd1c

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Catalytic activityi

sn-glycerol 3-phosphate + NAD+ = glycerone phosphate + NADH.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei97NADUniRule annotation1
Binding sitei120SubstrateUniRule annotation1
Binding sitei153NAD; via amide nitrogenUniRule annotation1
Active sitei204Proton acceptorUniRule annotation1
Binding sitei269NADUniRule annotation1
Binding sitei296NAD; via amide nitrogenUniRule annotation1
Binding sitei298NADUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi10 – 15NADUniRule annotation6

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductaseUniRule annotation
LigandNADUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Glycerol-3-phosphate dehydrogenase [NAD(+)]UniRule annotation (EC:1.1.1.8UniRule annotation)
Gene namesi
Name:gpd1cImported
Synonyms:gpd1Imported
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
Proteomesi
  • UP000000437 Componenti: Chromosome 19

Organism-specific databases

ZFINiZDB-GENE-040426-2576 gpd1c

Subcellular locationi

Expressioni

Gene expression databases

BgeeiENSDARG00000036942

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi7955.ENSDARP00000113739

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini5 – 172NAD_Gly3P_dh_NInterPro annotationAdd BLAST168
Domaini196 – 339NAD_Gly3P_dh_CInterPro annotationAdd BLAST144

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni269 – 270Substrate bindingUniRule annotation2

Sequence similaritiesi

Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.UniRule annotation

Phylogenomic databases

eggNOGiKOG2711 Eukaryota
COG0240 LUCA
GeneTreeiENSGT00390000003114
HOGENOMiHOG000246855
HOVERGENiHBG003669
KOiK00006
OMAiMEMVAFA
TreeFamiTF300836

Family and domain databases

Gene3Di1.10.1040.10, 1 hit
InterProiView protein in InterPro
IPR008927 6-PGluconate_DH-like_C_sf
IPR013328 6PGD_dom2
IPR006168 G3P_DH_NAD-dep
IPR006109 G3P_DH_NAD-dep_C
IPR017751 G3P_DH_NAD-dep_euk
IPR011128 G3P_DH_NAD-dep_N
IPR036291 NAD(P)-bd_dom_sf
PfamiView protein in Pfam
PF07479 NAD_Gly3P_dh_C, 1 hit
PF01210 NAD_Gly3P_dh_N, 1 hit
PIRSFiPIRSF000114 Glycerol-3-P_dh, 1 hit
PRINTSiPR00077 GPDHDRGNASE
SUPFAMiSSF48179 SSF48179, 1 hit
SSF51735 SSF51735, 1 hit
TIGRFAMsiTIGR03376 glycerol3P_DH, 1 hit
PROSITEiView protein in PROSITE
PS00957 NAD_G3PDH, 1 hit

Sequencei

Sequence statusi: Complete.

Q7T3H5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPGKKVCIIG SGNWGSAIAK IVGHNVKSSN RFEPLVKMWV YEEMIDGRKL
60 70 80 90 100
TEIINTEHEN VKYLPGHKLP KTVVAVPDVT EAASGADFLI FVIPHQFIVR
110 120 130 140 150
VCDQMKPHIK PGAIGISLIK GIDEGPDGLT LISDIIRAKL EIEVCVLMGA
160 170 180 190 200
NIASEVADEK FCETTIGATN EASGKLFKEL LQTPNFRITV VKESDTVELC
210 220 230 240 250
GALKNIVAVG AGFCDGLGFG DNTKAAVIRL GLMEMVAFSK LFCKSSVSSA
260 270 280 290 300
TFLESCGVAD LITTCYGGRN RRVAEAFART QKSIVELEAE MLNGQKLQGP
310 320 330 340
QTSAEVYKIL HKRNITDKFP LFVSVYQICF EGRQVKDFIN CLQNHPEHM
Length:349
Mass (Da):38,179
Last modified:October 1, 2003 - v1
Checksum:i43EFE27743393D0E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CABZ01079940 Genomic DNA No translation available.
CABZ01079941 Genomic DNA No translation available.
CABZ01079942 Genomic DNA No translation available.
CABZ01079943 Genomic DNA No translation available.
CABZ01090434 Genomic DNA No translation available.
CABZ01090435 Genomic DNA No translation available.
CABZ01101985 Genomic DNA No translation available.
CABZ01101986 Genomic DNA No translation available.
CABZ01101987 Genomic DNA No translation available.
CABZ01101988 Genomic DNA No translation available.
BC053116 mRNA Translation: AAH53116.1
RefSeqiNP_999918.1, NM_214753.2
UniGeneiDr.78758

Genome annotation databases

EnsembliENSDART00000053639; ENSDARP00000053638; ENSDARG00000036942
ENSDART00000134266; ENSDARP00000113739; ENSDARG00000036942
ENSDART00000169245; ENSDARP00000132643; ENSDARG00000036942
GeneIDi406615
KEGGidre:406615

Similar proteinsi

Entry informationi

Entry nameiQ7T3H5_DANRE
AccessioniPrimary (citable) accession number: Q7T3H5
Entry historyiIntegrated into UniProtKB/TrEMBL: October 1, 2003
Last sequence update: October 1, 2003
Last modified: May 23, 2018
This is version 122 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

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