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Q7T3H5

- Q7T3H5_DANRE

UniProt

Q7T3H5 - Q7T3H5_DANRE

Protein
Submitted name:

Glycerol-3-phosphate dehydrogenase 1 (Soluble)

Gene

gpd1c

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 93 (01 Oct 2014)
      Sequence version 1 (01 Oct 2003)
      Previous versions | rss
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    Functioni

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei120 – 1201SubstrateUniRule annotation
    Active sitei204 – 2041Proton acceptorUniRule annotation

    GO - Molecular functioni

    1. glycerol-3-phosphate dehydrogenase [NAD+] activity Source: InterPro
    2. NAD binding Source: InterPro

    GO - Biological processi

    1. carbohydrate metabolic process Source: InterPro
    2. glycerol-3-phosphate catabolic process Source: InterPro

    Keywords - Molecular functioni

    OxidoreductaseUniRule annotation

    Keywords - Ligandi

    NADUniRule annotation

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Glycerol-3-phosphate dehydrogenase 1 (Soluble)Imported
    Submitted name:
    Uncharacterized proteinImported
    Gene namesi
    Name:gpd1cImported
    Synonyms:gpd1Imported
    OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
    Taxonomic identifieri7955 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
    ProteomesiUP000000437: Chromosome 19

    Organism-specific databases

    ZFINiZDB-GENE-040426-2576. gpd1c.

    Subcellular locationi

    GO - Cellular componenti

    1. glycerol-3-phosphate dehydrogenase complex Source: InterPro

    Interactioni

    Protein-protein interaction databases

    STRINGi7955.ENSDARP00000053638.

    Family & Domainsi

    Region

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Regioni269 – 2702Substrate bindingUniRule annotation

    Sequence similaritiesi

    Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0240.
    GeneTreeiENSGT00390000003114.
    HOGENOMiHOG000246855.
    HOVERGENiHBG003669.
    InParanoidiQ7T3H5.
    KOiK00006.
    OMAiCKLLSTS.
    OrthoDBiEOG7ZKSBS.
    TreeFamiTF300836.

    Family and domain databases

    Gene3Di1.10.1040.10. 1 hit.
    3.40.50.720. 1 hit.
    InterProiIPR008927. 6-PGluconate_DH_C-like.
    IPR013328. DH_multihelical.
    IPR006168. G3P_DH_NAD-dep.
    IPR006109. G3P_DH_NAD-dep_C.
    IPR017751. G3P_DH_NAD-dep_euk.
    IPR011128. G3P_DH_NAD-dep_N.
    IPR016040. NAD(P)-bd_dom.
    [Graphical view]
    PANTHERiPTHR11728. PTHR11728. 1 hit.
    PfamiPF07479. NAD_Gly3P_dh_C. 1 hit.
    PF01210. NAD_Gly3P_dh_N. 1 hit.
    [Graphical view]
    PIRSFiPIRSF000114. Glycerol-3-P_dh. 1 hit.
    PRINTSiPR00077. GPDHDRGNASE.
    SUPFAMiSSF48179. SSF48179. 1 hit.
    TIGRFAMsiTIGR03376. glycerol3P_DH. 1 hit.
    PROSITEiPS00957. NAD_G3PDH. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q7T3H5-1 [UniParc]FASTAAdd to Basket

    « Hide

    MPGKKVCIIG SGNWGSAIAK IVGHNVKSSN RFEPLVKMWV YEEMIDGRKL    50
    TEIINTEHEN VKYLPGHKLP KTVVAVPDVT EAASGADFLI FVIPHQFIVR 100
    VCDQMKPHIK PGAIGISLIK GIDEGPDGLT LISDIIRAKL EIEVCVLMGA 150
    NIASEVADEK FCETTIGATN EASGKLFKEL LQTPNFRITV VKESDTVELC 200
    GALKNIVAVG AGFCDGLGFG DNTKAAVIRL GLMEMVAFSK LFCKSSVSSA 250
    TFLESCGVAD LITTCYGGRN RRVAEAFART QKSIVELEAE MLNGQKLQGP 300
    QTSAEVYKIL HKRNITDKFP LFVSVYQICF EGRQVKDFIN CLQNHPEHM 349
    Length:349
    Mass (Da):38,179
    Last modified:October 1, 2003 - v1
    Checksum:i43EFE27743393D0E
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CABZ01067085 Genomic DNA. No translation available.
    CABZ01067086 Genomic DNA. No translation available.
    CABZ01067087 Genomic DNA. No translation available.
    CABZ01068181 Genomic DNA. No translation available.
    CABZ01068182 Genomic DNA. No translation available.
    CABZ01075159 Genomic DNA. No translation available.
    CABZ01075160 Genomic DNA. No translation available.
    CABZ01075161 Genomic DNA. No translation available.
    CABZ01079940 Genomic DNA. No translation available.
    CABZ01079941 Genomic DNA. No translation available.
    CABZ01079942 Genomic DNA. No translation available.
    CABZ01079943 Genomic DNA. No translation available.
    CABZ01079950 Genomic DNA. No translation available.
    CABZ01079951 Genomic DNA. No translation available.
    CABZ01089718 Genomic DNA. No translation available.
    CABZ01090314 Genomic DNA. No translation available.
    CABZ01090315 Genomic DNA. No translation available.
    CABZ01090434 Genomic DNA. No translation available.
    CABZ01090435 Genomic DNA. No translation available.
    CABZ01091117 Genomic DNA. No translation available.
    CABZ01091118 Genomic DNA. No translation available.
    CABZ01101716 Genomic DNA. No translation available.
    CABZ01101717 Genomic DNA. No translation available.
    CABZ01101718 Genomic DNA. No translation available.
    CABZ01101719 Genomic DNA. No translation available.
    CABZ01101720 Genomic DNA. No translation available.
    CABZ01101985 Genomic DNA. No translation available.
    CABZ01101986 Genomic DNA. No translation available.
    CABZ01101987 Genomic DNA. No translation available.
    CABZ01101988 Genomic DNA. No translation available.
    CABZ01103845 Genomic DNA. No translation available.
    CABZ01103846 Genomic DNA. No translation available.
    CABZ01103847 Genomic DNA. No translation available.
    CABZ01103848 Genomic DNA. No translation available.
    CABZ01105353 Genomic DNA. No translation available.
    CABZ01110638 Genomic DNA. No translation available.
    CABZ01111719 Genomic DNA. No translation available.
    CR548627 Genomic DNA. No translation available.
    CU611039 Genomic DNA. No translation available.
    CU633999 Genomic DNA. No translation available.
    CU634003 Genomic DNA. No translation available.
    BC053116 mRNA. Translation: AAH53116.1.
    RefSeqiNP_999918.1. NM_214753.1.
    UniGeneiDr.78758.

    Genome annotation databases

    EnsembliENSDART00000053639; ENSDARP00000053638; ENSDARG00000036942.
    ENSDART00000134266; ENSDARP00000113739; ENSDARG00000036942.
    GeneIDi406615.
    KEGGidre:406615.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CABZ01067085 Genomic DNA. No translation available.
    CABZ01067086 Genomic DNA. No translation available.
    CABZ01067087 Genomic DNA. No translation available.
    CABZ01068181 Genomic DNA. No translation available.
    CABZ01068182 Genomic DNA. No translation available.
    CABZ01075159 Genomic DNA. No translation available.
    CABZ01075160 Genomic DNA. No translation available.
    CABZ01075161 Genomic DNA. No translation available.
    CABZ01079940 Genomic DNA. No translation available.
    CABZ01079941 Genomic DNA. No translation available.
    CABZ01079942 Genomic DNA. No translation available.
    CABZ01079943 Genomic DNA. No translation available.
    CABZ01079950 Genomic DNA. No translation available.
    CABZ01079951 Genomic DNA. No translation available.
    CABZ01089718 Genomic DNA. No translation available.
    CABZ01090314 Genomic DNA. No translation available.
    CABZ01090315 Genomic DNA. No translation available.
    CABZ01090434 Genomic DNA. No translation available.
    CABZ01090435 Genomic DNA. No translation available.
    CABZ01091117 Genomic DNA. No translation available.
    CABZ01091118 Genomic DNA. No translation available.
    CABZ01101716 Genomic DNA. No translation available.
    CABZ01101717 Genomic DNA. No translation available.
    CABZ01101718 Genomic DNA. No translation available.
    CABZ01101719 Genomic DNA. No translation available.
    CABZ01101720 Genomic DNA. No translation available.
    CABZ01101985 Genomic DNA. No translation available.
    CABZ01101986 Genomic DNA. No translation available.
    CABZ01101987 Genomic DNA. No translation available.
    CABZ01101988 Genomic DNA. No translation available.
    CABZ01103845 Genomic DNA. No translation available.
    CABZ01103846 Genomic DNA. No translation available.
    CABZ01103847 Genomic DNA. No translation available.
    CABZ01103848 Genomic DNA. No translation available.
    CABZ01105353 Genomic DNA. No translation available.
    CABZ01110638 Genomic DNA. No translation available.
    CABZ01111719 Genomic DNA. No translation available.
    CR548627 Genomic DNA. No translation available.
    CU611039 Genomic DNA. No translation available.
    CU633999 Genomic DNA. No translation available.
    CU634003 Genomic DNA. No translation available.
    BC053116 mRNA. Translation: AAH53116.1 .
    RefSeqi NP_999918.1. NM_214753.1.
    UniGenei Dr.78758.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 7955.ENSDARP00000053638.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSDART00000053639 ; ENSDARP00000053638 ; ENSDARG00000036942 .
    ENSDART00000134266 ; ENSDARP00000113739 ; ENSDARG00000036942 .
    GeneIDi 406615.
    KEGGi dre:406615.

    Organism-specific databases

    CTDi 406615.
    ZFINi ZDB-GENE-040426-2576. gpd1c.

    Phylogenomic databases

    eggNOGi COG0240.
    GeneTreei ENSGT00390000003114.
    HOGENOMi HOG000246855.
    HOVERGENi HBG003669.
    InParanoidi Q7T3H5.
    KOi K00006.
    OMAi CKLLSTS.
    OrthoDBi EOG7ZKSBS.
    TreeFami TF300836.

    Miscellaneous databases

    NextBioi 20818161.

    Family and domain databases

    Gene3Di 1.10.1040.10. 1 hit.
    3.40.50.720. 1 hit.
    InterProi IPR008927. 6-PGluconate_DH_C-like.
    IPR013328. DH_multihelical.
    IPR006168. G3P_DH_NAD-dep.
    IPR006109. G3P_DH_NAD-dep_C.
    IPR017751. G3P_DH_NAD-dep_euk.
    IPR011128. G3P_DH_NAD-dep_N.
    IPR016040. NAD(P)-bd_dom.
    [Graphical view ]
    PANTHERi PTHR11728. PTHR11728. 1 hit.
    Pfami PF07479. NAD_Gly3P_dh_C. 1 hit.
    PF01210. NAD_Gly3P_dh_N. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF000114. Glycerol-3-P_dh. 1 hit.
    PRINTSi PR00077. GPDHDRGNASE.
    SUPFAMi SSF48179. SSF48179. 1 hit.
    TIGRFAMsi TIGR03376. glycerol3P_DH. 1 hit.
    PROSITEi PS00957. NAD_G3PDH. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. NIH - Zebrafish Gene Collection (ZGC) project
      Submitted (JUN-2003) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Tissue: EmbryoImported.
    2. Ensembl
      Submitted (FEB-2012) to UniProtKB
      Cited for: IDENTIFICATION.
      Strain: TuebingenImported.
    3. "The zebrafish reference genome sequence and its relationship to the human genome."
      Howe K., Clark M.D., Torroja C.F., Torrance J., Berthelot C., Muffato M., Collins J.E., Humphray S., McLaren K., Matthews L., McLaren S., Sealy I., Caccamo M., Churcher C., Scott C., Barrett J.C., Koch R., Rauch G.J.
      , White S., Chow W., Kilian B., Quintais L.T., Guerra-Assuncao J.A., Zhou Y., Gu Y., Yen J., Vogel J.H., Eyre T., Redmond S., Banerjee R., Chi J., Fu B., Langley E., Maguire S.F., Laird G.K., Lloyd D., Kenyon E., Donaldson S., Sehra H., Almeida-King J., Loveland J., Trevanion S., Jones M., Quail M., Willey D., Hunt A., Burton J., Sims S., McLay K., Plumb B., Davis J., Clee C., Oliver K., Clark R., Riddle C., Eliott D., Threadgold G., Harden G., Ware D., Mortimer B., Kerry G., Heath P., Phillimore B., Tracey A., Corby N., Dunn M., Johnson C., Wood J., Clark S., Pelan S., Griffiths G., Smith M., Glithero R., Howden P., Barker N., Stevens C., Harley J., Holt K., Panagiotidis G., Lovell J., Beasley H., Henderson C., Gordon D., Auger K., Wright D., Collins J., Raisen C., Dyer L., Leung K., Robertson L., Ambridge K., Leongamornlert D., McGuire S., Gilderthorp R., Griffiths C., Manthravadi D., Nichol S., Barker G., Whitehead S., Kay M., Brown J., Murnane C., Gray E., Humphries M., Sycamore N., Barker D., Saunders D., Wallis J., Babbage A., Hammond S., Mashreghi-Mohammadi M., Barr L., Martin S., Wray P., Ellington A., Matthews N., Ellwood M., Woodmansey R., Clark G., Cooper J., Tromans A., Grafham D., Skuce C., Pandian R., Andrews R., Harrison E., Kimberley A., Garnett J., Fosker N., Hall R., Garner P., Kelly D., Bird C., Palmer S., Gehring I., Berger A., Dooley C.M., Ersan-Urun Z., Eser C., Geiger H., Geisler M., Karotki L., Kirn A., Konantz J., Konantz M., Oberlander M., Rudolph-Geiger S., Teucke M., Osoegawa K., Zhu B., Rapp A., Widaa S., Langford C., Yang F., Carter N.P., Harrow J., Ning Z., Herrero J., Searle S.M., Enright A., Geisler R., Plasterk R.H., Lee C., Westerfield M., de Jong P.J., Zon L.I., Postlethwait J.H., Nusslein-Volhard C., Hubbard T.J., Roest Crollius H., Rogers J., Stemple D.L.
      Nature 496:498-503(2013) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: TuebingenImported.

    Entry informationi

    Entry nameiQ7T3H5_DANRE
    AccessioniPrimary (citable) accession number: Q7T3H5
    Entry historyi
    Integrated into UniProtKB/TrEMBL: October 1, 2003
    Last sequence update: October 1, 2003
    Last modified: October 1, 2014
    This is version 93 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3