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Protein
Submitted name:

Guanine nucleotide-binding protein (G protein), alpha-inhibiting activity polypeptide 1

Gene

gnai1

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionTransducerSAAS annotation
LigandGTP-bindingSAAS annotation, Nucleotide-binding

Enzyme and pathway databases

ReactomeiR-DRE-112043 PLC beta mediated events
R-DRE-170670 Adenylate cyclase inhibitory pathway
R-DRE-202040 G-protein activation
R-DRE-392170 ADP signalling through P2Y purinoceptor 12
R-DRE-400042 Adrenaline,noradrenaline inhibits insulin secretion
R-DRE-418594 G alpha (i) signalling events
R-DRE-6814122 Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding

Names & Taxonomyi

Protein namesi
Submitted name:
Guanine nucleotide-binding protein (G protein), alpha-inhibiting activity polypeptide 1Imported
Gene namesi
Name:gnai1Imported
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
Proteomesi
  • UP000000437 Componenti: Chromosome 4

Organism-specific databases

ZFINiZDB-GENE-040426-1310 gnai1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Expressioni

Gene expression databases

BgeeiENSDARG00000021647

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi7955.ENSDARP00000037326

Family & Domainsi

Phylogenomic databases

eggNOGiKOG0082 Eukaryota
ENOG410XNVQ LUCA
GeneTreeiENSGT00760000118851
HOGENOMiHOG000038730
HOVERGENiHBG063184
KOiK04630
OMAiRIAQTSY
OrthoDBiEOG091G0VUT
TreeFamiTF300673

Family and domain databases

CDDicd00066 G-alpha, 1 hit
Gene3Di1.10.400.10, 1 hit
InterProiView protein in InterPro
IPR001408 Gprotein_alpha_I
IPR001019 Gprotein_alpha_su
IPR011025 GproteinA_insert
IPR027417 P-loop_NTPase
PANTHERiPTHR10218 PTHR10218, 1 hit
PfamiView protein in Pfam
PF00503 G-alpha, 1 hit
PRINTSiPR00318 GPROTEINA
PR00441 GPROTEINAI
SMARTiView protein in SMART
SM00275 G_alpha, 1 hit
SUPFAMiSSF47895 SSF47895, 1 hit
SSF52540 SSF52540, 2 hits

Sequencei

Sequence statusi: Complete.

Q7T3D3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGCTLSTEDK AAVERSKMID RNLRDDGEKA AREVKLLLLG AGESGKSTIV
60 70 80 90 100
KQMKIIHEAG YSEEECKQYK AVVYSNTIQS IIAIIRAMGR LKIDFGDAAR
110 120 130 140 150
ADDARQLFVL AGSAEEGFMT AELAGVIKRL WKDGGVQACF SRSREYQLND
160 170 180 190 200
SAAYYLNDLD RISQATYIPT QQDVLRTRVK TTGIVETHFT FKDLHFKMFD
210 220 230 240 250
VGGQRSERKK WIHCFEGVTA IIFCVALSDY DLVLAEDEEM NRMHESMKLF
260 270 280 290 300
DSICNNKWFT DTSIILFLNK KDLFEEKIRK STLTICYPEY AGSNTYEEAA
310 320 330 340 350
AYIQCQFEDL NKRKDTKEIY THFTCATDTK NVQFVFDAVT DVIIKNNLKD

CGLF
Length:354
Mass (Da):40,329
Last modified:October 1, 2003 - v1
Checksum:iAF9B7A3F0E0DA01C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX897665 Genomic DNA No translation available.
BC053164 mRNA Translation: AAH53164.1
BC154335 mRNA Translation: AAI54336.1
RefSeqiNP_957265.1, NM_200971.1
UniGeneiDr.14593

Genome annotation databases

EnsembliENSDART00000036531; ENSDARP00000037326; ENSDARG00000021647
GeneIDi393946
KEGGidre:393946

Similar proteinsi

Entry informationi

Entry nameiQ7T3D3_DANRE
AccessioniPrimary (citable) accession number: Q7T3D3
Entry historyiIntegrated into UniProtKB/TrEMBL: October 1, 2003
Last sequence update: October 1, 2003
Last modified: March 28, 2018
This is version 114 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
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Main funding by: National Institutes of Health