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Protein

Tumor necrosis factor alpha-induced protein 8-like protein 3

Gene

tnfaip8l3

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

May act as a lipid transfer protein.By similarity

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Lipid transport, Transport

Names & Taxonomyi

Protein namesi
Recommended name:
Tumor necrosis factor alpha-induced protein 8-like protein 3
Short name:
TNF alpha-induced protein 8-like protein 3
Short name:
TNFAIP8-like protein 3
Gene namesi
Name:tnfaip8l3
ORF Names:si:ch211-12a1.1, zgc:63960
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
Proteomesi
  • UP000000437 Componenti: Chromosome 18

Organism-specific databases

ZFINiZDB-GENE-040426-1313. tnfaip8l3.

Subcellular locationi

  • Cytoplasm By similarity
  • Cell membrane By similarity

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Cytoplasm, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 202202Tumor necrosis factor alpha-induced protein 8-like protein 3PRO_0000331426Add
BLAST

Proteomic databases

PaxDbiQ7T3D0.

Expressioni

Gene expression databases

BgeeiQ7T3D0.

Family & Domainsi

Sequence similaritiesi

Belongs to the TNFAIP8 family.Curated

Phylogenomic databases

eggNOGiENOG410IE5H. Eukaryota.
ENOG4111HNU. LUCA.
GeneTreeiENSGT00390000003488.
HOGENOMiHOG000007708.
HOVERGENiHBG053286.
InParanoidiQ7T3D0.
OMAiMVSFYEV.
OrthoDBiEOG7P5T2H.
PhylomeDBiQ7T3D0.
TreeFamiTF323415.

Family and domain databases

InterProiIPR008477. DUF758.
[Graphical view]
PANTHERiPTHR12757. PTHR12757. 1 hit.
PfamiPF05527. DUF758. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q7T3D0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDSDSGEQSE GELSPGHESF NSKSLALQAQ KKILSKMATM AVANLLTDDT
60 70 80 90 100
SSEILDELYK ASREYTKSKK EAHKIIKDVI KIALKIGILY RNHQFSPEEM
110 120 130 140 150
ETVERFKKKM NQAAMTVVSF YEVEYTFDRG ILSELLLECR DLLHELVEHH
160 170 180 190 200
LTMRSHGRID HVFNHFADVD FLTELYGPSE DYRLNLRKIC DGINKLLDEG

TL
Length:202
Mass (Da):23,200
Last modified:October 1, 2003 - v1
Checksum:iC18FEB0342213D5F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX908722, BX927313 Genomic DNA. Translation: CAK04220.1.
BX927313, BX908722 Genomic DNA. Translation: CAM56316.1.
BC053167 mRNA. Translation: AAH53167.1.
RefSeqiNP_956645.1. NM_200351.1.
UniGeneiDr.83273.

Genome annotation databases

EnsembliENSDART00000125116; ENSDARP00000112471; ENSDARG00000088709.
GeneIDi393322.
KEGGidre:393322.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX908722, BX927313 Genomic DNA. Translation: CAK04220.1.
BX927313, BX908722 Genomic DNA. Translation: CAM56316.1.
BC053167 mRNA. Translation: AAH53167.1.
RefSeqiNP_956645.1. NM_200351.1.
UniGeneiDr.83273.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PaxDbiQ7T3D0.

Protocols and materials databases

DNASUi393322.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSDART00000125116; ENSDARP00000112471; ENSDARG00000088709.
GeneIDi393322.
KEGGidre:393322.

Organism-specific databases

CTDi388121.
ZFINiZDB-GENE-040426-1313. tnfaip8l3.

Phylogenomic databases

eggNOGiENOG410IE5H. Eukaryota.
ENOG4111HNU. LUCA.
GeneTreeiENSGT00390000003488.
HOGENOMiHOG000007708.
HOVERGENiHBG053286.
InParanoidiQ7T3D0.
OMAiMVSFYEV.
OrthoDBiEOG7P5T2H.
PhylomeDBiQ7T3D0.
TreeFamiTF323415.

Miscellaneous databases

NextBioi20814374.
PROiQ7T3D0.

Gene expression databases

BgeeiQ7T3D0.

Family and domain databases

InterProiIPR008477. DUF758.
[Graphical view]
PANTHERiPTHR12757. PTHR12757. 1 hit.
PfamiPF05527. DUF758. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "The zebrafish reference genome sequence and its relationship to the human genome."
    Howe K., Clark M.D., Torroja C.F., Torrance J., Berthelot C., Muffato M., Collins J.E., Humphray S., McLaren K., Matthews L., McLaren S., Sealy I., Caccamo M., Churcher C., Scott C., Barrett J.C., Koch R., Rauch G.J.
    , White S., Chow W., Kilian B., Quintais L.T., Guerra-Assuncao J.A., Zhou Y., Gu Y., Yen J., Vogel J.H., Eyre T., Redmond S., Banerjee R., Chi J., Fu B., Langley E., Maguire S.F., Laird G.K., Lloyd D., Kenyon E., Donaldson S., Sehra H., Almeida-King J., Loveland J., Trevanion S., Jones M., Quail M., Willey D., Hunt A., Burton J., Sims S., McLay K., Plumb B., Davis J., Clee C., Oliver K., Clark R., Riddle C., Eliott D., Threadgold G., Harden G., Ware D., Mortimer B., Kerry G., Heath P., Phillimore B., Tracey A., Corby N., Dunn M., Johnson C., Wood J., Clark S., Pelan S., Griffiths G., Smith M., Glithero R., Howden P., Barker N., Stevens C., Harley J., Holt K., Panagiotidis G., Lovell J., Beasley H., Henderson C., Gordon D., Auger K., Wright D., Collins J., Raisen C., Dyer L., Leung K., Robertson L., Ambridge K., Leongamornlert D., McGuire S., Gilderthorp R., Griffiths C., Manthravadi D., Nichol S., Barker G., Whitehead S., Kay M., Brown J., Murnane C., Gray E., Humphries M., Sycamore N., Barker D., Saunders D., Wallis J., Babbage A., Hammond S., Mashreghi-Mohammadi M., Barr L., Martin S., Wray P., Ellington A., Matthews N., Ellwood M., Woodmansey R., Clark G., Cooper J., Tromans A., Grafham D., Skuce C., Pandian R., Andrews R., Harrison E., Kimberley A., Garnett J., Fosker N., Hall R., Garner P., Kelly D., Bird C., Palmer S., Gehring I., Berger A., Dooley C.M., Ersan-Urun Z., Eser C., Geiger H., Geisler M., Karotki L., Kirn A., Konantz J., Konantz M., Oberlander M., Rudolph-Geiger S., Teucke M., Osoegawa K., Zhu B., Rapp A., Widaa S., Langford C., Yang F., Carter N.P., Harrow J., Ning Z., Herrero J., Searle S.M., Enright A., Geisler R., Plasterk R.H., Lee C., Westerfield M., de Jong P.J., Zon L.I., Postlethwait J.H., Nusslein-Volhard C., Hubbard T.J., Roest Crollius H., Rogers J., Stemple D.L.
    Nature 496:498-503(2013) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Tuebingen.
  2. NIH - Zebrafish Gene Collection (ZGC) project
    Submitted (JUN-2003) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Kidney.

Entry informationi

Entry nameiTP8L3_DANRE
AccessioniPrimary (citable) accession number: Q7T3D0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 29, 2008
Last sequence update: October 1, 2003
Last modified: May 11, 2016
This is version 70 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.