Q7T2T7 (Q7T2T7_DANRE) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Methyl CpG binding protein 2 Ensembl ENSDARP00000109399 EMBL CAP19552.1

Submitted name:
Methyl-cytosine binding protein 2 EMBL AAP57248.2

Gene names

Name:	mecp2 Ensembl ENSDARP00000109399 EMBL AAP57248.2 ZFIN ZDB-GENE-030131-7190
ORF Names:	CH211-192F24.1-002 EMBL CAP19552.1

Organism

Danio rerio (Zebrafish) (Brachydanio rerio) EMBL AAP57248.2

Taxonomic identifier

7955 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Actinopterygii › Neopterygii › Teleostei › Ostariophysi › Cypriniformes › Cyprinidae › Danio

Protein attributes

Sequence length	524 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

Ontologies

Keywords
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Cellular component	nucleus Inferred from electronic annotation. Source: InterPro
Molecular function	DNA binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q7T2T7 [UniParc]. Last modified July 5, 2004. Version 2. Checksum: B8593B4BB84DC2D1	FASTA	524	57,152
	10 20 30 40 50 60 MAAAESGEER LRGEDKNEDQ EGSKDKTQKH KKSKKERHDV EKLETTVSVP PPPSLFTQRD 70 80 90 100 110 120 VGQQAEAGKS EPIDPEVGAA LSAPESSASA KQRRSVIRDR GPMYEDPSLP QGWTRKLKQR 130 140 150 160 170 180 KSGRSAGKFD VYLINPEGKA FRSKVELMAY FQKVGDTITD PNDFDFTVTG RGSPSRREKR 190 200 210 220 230 240 PPKKPKMVKP SGRGRGRPKG SGKVRQATEG VAVKRVIEKS PGKLLVKMPF VAPKTEPGAP 250 260 270 280 290 300 LGQAPVAKAR RGRKRKSEQD PPSTPKKRGR KPATVSQSTV GTGSAAAYAA AAILTAEAKK 310 320 330 340 350 360 KALKESSAKP VQERALPIKK RKTRETLEEL EASTTSATET FEKRLTASTV TPTGEEAETG 370 380 390 400 410 420 QKPHKHPSRK HKEADPGSSS SGTTASGVAP KSHKKRDQRG QHFKHHHHHH HHHHQHQHLQ 430 440 450 460 470 480 ASTPSTYTPQ AHQLSLGHST HGGLENEPQD LSTSRPKAEH VACREEARTG SSSSRDSQNA 490 500 510 520 SKMASMTVTG ESKELRDIVP PSAVPRPSRE ETVESRTPVS EPVS

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Differential expression of the methyl-cytosine binding protein 2 gene in embryonic and adult brain of zebrafish." Coverdale L.E., Martyniuk C.J., Trudeau V.L., Martin C.C. Brain Res. Dev. Brain Res. 153:281-287(2004) [PubMed: 15527897] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.
[2]	Tracey A. Submitted (JAN-2009) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
[3]	Glithero R. Submitted (JAN-2009) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
[4]	"The genomic sequence of Danio rerio." The Danio rerio Sequencing Project at the Sanger Institute Submitted (JUL-2010) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Tuebingen Ensembl ENSDARP00000109399.
[5]	Ensembl Submitted (JUL-2011) to UniProtKB Cited for: IDENTIFICATION. Strain: Tuebingen Ensembl ENSDARP00000109399.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AY298900 mRNA. Translation: AAP57248.2. BX571687, CR352304 Genomic DNA. Translation: CAP19552.1. CR352304, BX571687 Genomic DNA. Translation: CAQ14979.1.
IPI	IPI00485015.
RefSeq	NP_997901.1. NM_212736.1.
UniGene	Dr.82151.
3D structure databases
HSSP	HSSP built from PDB template 1IG4 based on UniProtKB Q9UNZ9.
ProteinModelPortal	Q7T2T7.
ModBase	Search...
Protein-protein interaction databases
STRING	Q7T2T7.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENSDART00000123882; ENSDARP00000109399; ENSDARG00000014218.
GeneID	335250.
KEGG	dre:335250.
Organism-specific databases
CTD	4204.
ZFIN	ZDB-GENE-030131-7190. mecp2.
Phylogenomic databases
GeneTree	ENSGT00530000063687.
HOGENOM	HBG268178.
HOVERGEN	HBG052445.
InParanoid	Q7T2T7.
OMA	PQGWTRK.
Gene expression databases
ArrayExpress	Q7T2T7.
Bgee	Q7T2T7.
Family and domain databases
InterPro	IPR016177. DNA-bd_integrase-typ. IPR017353. Me_CpG-bd_MeCP2. IPR001739. Methyl_CpG_DNA-bd. [Graphical view]
Gene3D	G3DSA:3.30.890.10. Methyl_CpG_DNA-bd. 1 hit.
KO	K11588.
Pfam	PF01429. MBD. 1 hit. [Graphical view]
PIRSF	PIRSF038006. Methyl_CpG_bd_MeCP2. 1 hit.
SMART	SM00391. MBD. 1 hit. [Graphical view]
SUPFAM	SSF54171. DNA-binding_integrase-type. 1 hit.
PROSITE	PS50982. MBD. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q7T2T7_DANRE

Accession

Primary (citable) accession number: Q7T2T7

Entry history

Integrated into UniProtKB/TrEMBL:	October 1, 2003
Last sequence update:	July 5, 2004
Last modified:	January 25, 2012
This is version 51 of the entry and version 2 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)