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Protein
Submitted name:

Arrb2b protein

Gene

arrb2b

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Biological processi

  • muscle organ development Source: ZFIN
  • regulation of chemokine activity Source: ZFIN
  • regulation of receptor recycling Source: ZFIN
  • regulation of smoothened signaling pathway Source: ZFIN
  • signal transduction Source: InterPro

Enzyme and pathway databases

ReactomeiR-DRE-418555 G alpha (s) signalling events
R-DRE-456926 Thrombin signalling through proteinase activated receptors (PARs)
R-DRE-5099900 WNT5A-dependent internalization of FZD4
R-DRE-5635838 Activation of SMO
R-DRE-5674135 MAP2K and MAPK activation
R-DRE-5689880 Ub-specific processing proteases
R-DRE-8856825 Cargo recognition for clathrin-mediated endocytosis
R-DRE-8856828 Clathrin-mediated endocytosis

Names & Taxonomyi

Protein namesi
Submitted name:
Arrb2b proteinImported
Submitted name:
Arrestin, beta 2bImported
Gene namesi
Name:arrb2bImported
Synonyms:arrb2Imported
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
Proteomesi
  • UP000000437 Componenti: Chromosome 7

Organism-specific databases

ZFINiZDB-GENE-040426-1332 arrb2b

Expressioni

Gene expression databases

BgeeiENSDARG00000011545

Interactioni

Protein-protein interaction databases

STRINGi7955.ENSDARP00000024694

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini194 – 349Arrestin_CInterPro annotationAdd BLAST156

Phylogenomic databases

eggNOGiKOG3865 Eukaryota
ENOG410XR0F LUCA
GeneTreeiENSGT00390000013152
HOGENOMiHOG000231319
HOVERGENiHBG002399
KOiK04439
OMAiPKPHDHI
OrthoDBiEOG091G05M2
TreeFamiTF314260

Family and domain databases

Gene3Di2.60.40.640, 1 hit
2.60.40.840, 1 hit
InterProiView protein in InterPro
IPR000698 Arrestin
IPR011021 Arrestin-like_N
IPR014752 Arrestin_C
IPR011022 Arrestin_C-like
IPR017864 Arrestin_CS
IPR014753 Arrestin_N
IPR014756 Ig_E-set
PANTHERiPTHR11792 PTHR11792, 1 hit
PfamiView protein in Pfam
PF02752 Arrestin_C, 1 hit
PF00339 Arrestin_N, 1 hit
PRINTSiPR00309 ARRESTIN
SMARTiView protein in SMART
SM01017 Arrestin_C, 1 hit
SUPFAMiSSF81296 SSF81296, 2 hits
PROSITEiView protein in PROSITE
PS00295 ARRESTINS, 1 hit

Sequencei

Sequence statusi: Complete.

Q7T2D2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGDKAGTRVF KKSSPNCKLT VYLGKRDFVD HLDHVDPVDG VLLIDPEYLK
60 70 80 90 100
DRKVFVTLTC AFRYGREDLD VLGLSFRKDL FISSFQAYPP LPDERKPLSR
110 120 130 140 150
LQERLLKKLG QNAYPFNFTI PQNLPCSVTL QPGPEDTGKA CGVDFEVRAF
160 170 180 190 200
CAKTVDEKTH KRNSVRLVIR KVQYAPEKPG PQPMVETTRS FLMSDRSLHL
210 220 230 240 250
EASLDKELYY HGEPISVNVH VTNNSTKTVK RVKISVRQYA DICLFSTAQY
260 270 280 290 300
KCPVAQVEAD DQVSSSSTFC KVYTLTPTLS NNREKRGLAL DGQLKHEDTN
310 320 330 340 350
LASSTIVKDV SNKEVLGILV SYRVKVKLVV SRGGDVSVEL PFVLMHPKPS
360 370 380 390 400
EQPNSRPQSA VPETDVPVDA NLIEFETNNF SQDDDFVFED FARLRLKGMK

DEEDDHFC
Length:408
Mass (Da):46,057
Last modified:October 1, 2003 - v1
Checksum:iDCC7FE40A8E67A00
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX005022 Genomic DNA No translation available.
BC054595 mRNA Translation: AAH54595.1
BC164508 mRNA Translation: AAI64508.1
RefSeqiNP_957418.1, NM_201124.1
UniGeneiDr.132395

Genome annotation databases

EnsembliENSDART00000026295; ENSDARP00000024694; ENSDARG00000011545
GeneIDi394099
KEGGidre:394099

Similar proteinsi

Entry informationi

Entry nameiQ7T2D2_DANRE
AccessioniPrimary (citable) accession number: Q7T2D2
Entry historyiIntegrated into UniProtKB/TrEMBL: October 1, 2003
Last sequence update: October 1, 2003
Last modified: March 28, 2018
This is version 99 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

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