Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Phb

Gene

phb

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

Enzyme and pathway databases

ReactomeiR-DRE-5673000. RAF activation.

Names & Taxonomyi

Protein namesi
Submitted name:
PhbImported
Submitted name:
Phb proteinImported
Submitted name:
ProhibitinImported
Submitted name:
Uncharacterized proteinImported
Gene namesi
Name:phbImported
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
Proteomesi
  • UP000000437 Componenti: Chromosome 3

Organism-specific databases

ZFINiZDB-GENE-030131-6577. phb.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Interactioni

Protein-protein interaction databases

STRINGi7955.ENSDARP00000098348.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini25 – 186162PHBInterPro annotationAdd
BLAST

Phylogenomic databases

eggNOGiKOG3083. Eukaryota.
COG0330. LUCA.
GeneTreeiENSGT00550000074770.
HOGENOMiHOG000205692.
HOVERGENiHBG004457.
KOiK17080.
OMAiYLNIGLD.
OrthoDBiEOG7V4B04.

Family and domain databases

InterProiIPR001107. Band_7.
IPR000163. Prohibitin.
[Graphical view]
PANTHERiPTHR23222. PTHR23222. 1 hit.
PfamiPF01145. Band_7. 1 hit.
[Graphical view]
PRINTSiPR00679. PROHIBITIN.
SMARTiSM00244. PHB. 1 hit.
[Graphical view]
SUPFAMiSSF117892. SSF117892. 1 hit.

Sequencei

Sequence statusi: Complete.

Q7T1D8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAKLFESIGK LGLALAIGGG VVNSALYNVD AGHRAVIFDR FRGVQDVVVG
60 70 80 90 100
EGTHFLIPWV QKPIIFDCRS RPRNVPVITG SKDLQNVNIT LRILFRPVAG
110 120 130 140 150
QLPRIFTSIG EDYDERVLPS ITTEVLKSVV ARFDAGELIT QRELVSRQVS
160 170 180 190 200
EDLTERASTF GLILDDVSLT HLTFGKEFTE AVEMKQVAQQ EAERARFVVE
210 220 230 240 250
KAEQQKQAAI ISAEGDSQAA LLIANSLAEA GDGLVELRKL EAAEDIAFQL
260 270
SRARNVTYLP SGQGTLLQLP Q
Length:271
Mass (Da):29,685
Last modified:October 1, 2003 - v1
Checksum:i8B50D1F9CA6088B3
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei271 – 2711Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX936308 Genomic DNA. No translation available.
BC055384 mRNA. Translation: AAH55384.1.
BC065895 mRNA. Translation: AAH65895.1.
KM655719 mRNA. Translation: AJG06065.1.
RefSeqiNP_958454.1. NM_201297.1.
XP_009297546.1. XM_009299271.1.
UniGeneiDr.75876.

Genome annotation databases

EnsembliENSDART00000080075; ENSDARP00000074525; ENSDARG00000057414.
GeneIDi321346.
KEGGidre:321346.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX936308 Genomic DNA. No translation available.
BC055384 mRNA. Translation: AAH55384.1.
BC065895 mRNA. Translation: AAH65895.1.
KM655719 mRNA. Translation: AJG06065.1.
RefSeqiNP_958454.1. NM_201297.1.
XP_009297546.1. XM_009299271.1.
UniGeneiDr.75876.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi7955.ENSDARP00000098348.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSDART00000080075; ENSDARP00000074525; ENSDARG00000057414.
GeneIDi321346.
KEGGidre:321346.

Organism-specific databases

CTDi5245.
ZFINiZDB-GENE-030131-6577. phb.

Phylogenomic databases

eggNOGiKOG3083. Eukaryota.
COG0330. LUCA.
GeneTreeiENSGT00550000074770.
HOGENOMiHOG000205692.
HOVERGENiHBG004457.
KOiK17080.
OMAiYLNIGLD.
OrthoDBiEOG7V4B04.

Enzyme and pathway databases

ReactomeiR-DRE-5673000. RAF activation.

Family and domain databases

InterProiIPR001107. Band_7.
IPR000163. Prohibitin.
[Graphical view]
PANTHERiPTHR23222. PTHR23222. 1 hit.
PfamiPF01145. Band_7. 1 hit.
[Graphical view]
PRINTSiPR00679. PROHIBITIN.
SMARTiSM00244. PHB. 1 hit.
[Graphical view]
SUPFAMiSSF117892. SSF117892. 1 hit.
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. NIH - Zebrafish Gene Collection (ZGC) project
    Submitted (JUL-2003) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: KidneyImported.
  2. NIH - Zebrafish Gene Collection (ZGC) project
    Submitted (JAN-2004) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: WholeImported.
  3. Ensembl
    Submitted (FEB-2012) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: TuebingenImported.
  4. "The zebrafish reference genome sequence and its relationship to the human genome."
    Howe K., Clark M.D., Torroja C.F., Torrance J., Berthelot C., Muffato M., Collins J.E., Humphray S., McLaren K., Matthews L., McLaren S., Sealy I., Caccamo M., Churcher C., Scott C., Barrett J.C., Koch R., Rauch G.J.
    , White S., Chow W., Kilian B., Quintais L.T., Guerra-Assuncao J.A., Zhou Y., Gu Y., Yen J., Vogel J.H., Eyre T., Redmond S., Banerjee R., Chi J., Fu B., Langley E., Maguire S.F., Laird G.K., Lloyd D., Kenyon E., Donaldson S., Sehra H., Almeida-King J., Loveland J., Trevanion S., Jones M., Quail M., Willey D., Hunt A., Burton J., Sims S., McLay K., Plumb B., Davis J., Clee C., Oliver K., Clark R., Riddle C., Elliot D., Threadgold G., Harden G., Ware D., Begum S., Mortimore B., Kerry G., Heath P., Phillimore B., Tracey A., Corby N., Dunn M., Johnson C., Wood J., Clark S., Pelan S., Griffiths G., Smith M., Glithero R., Howden P., Barker N., Lloyd C., Stevens C., Harley J., Holt K., Panagiotidis G., Lovell J., Beasley H., Henderson C., Gordon D., Auger K., Wright D., Collins J., Raisen C., Dyer L., Leung K., Robertson L., Ambridge K., Leongamornlert D., McGuire S., Gilderthorp R., Griffiths C., Manthravadi D., Nichol S., Barker G., Whitehead S., Kay M., Brown J., Murnane C., Gray E., Humphries M., Sycamore N., Barker D., Saunders D., Wallis J., Babbage A., Hammond S., Mashreghi-Mohammadi M., Barr L., Martin S., Wray P., Ellington A., Matthews N., Ellwood M., Woodmansey R., Clark G., Cooper J., Tromans A., Grafham D., Skuce C., Pandian R., Andrews R., Harrison E., Kimberley A., Garnett J., Fosker N., Hall R., Garner P., Kelly D., Bird C., Palmer S., Gehring I., Berger A., Dooley C.M., Ersan-Urun Z., Eser C., Geiger H., Geisler M., Karotki L., Kirn A., Konantz J., Konantz M., Oberlander M., Rudolph-Geiger S., Teucke M., Lanz C., Raddatz G., Osoegawa K., Zhu B., Rapp A., Widaa S., Langford C., Yang F., Schuster S.C., Carter N.P., Harrow J., Ning Z., Herrero J., Searle S.M., Enright A., Geisler R., Plasterk R.H., Lee C., Westerfield M., de Jong P.J., Zon L.I., Postlethwait J.H., Nusslein-Volhard C., Hubbard T.J., Roest Crollius H., Rogers J., Stemple D.L.
    Nature 496:498-503(2013) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: TuebingenImported.
  5. "A Floor-Plate Extracellular Protein-Protein Interaction Screen Identifies Draxin as a Secreted Netrin-1 Antagonist."
    Gao X., Metzger U., Panza P., Mahalwar P., Alsheimer S., Geiger H., Maischein H.M., Levesque M.P., Templin M., Sollner C.
    Cell Rep. 12:694-708(2015) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiQ7T1D8_DANRE
AccessioniPrimary (citable) accession number: Q7T1D8
Entry historyi
Integrated into UniProtKB/TrEMBL: October 1, 2003
Last sequence update: October 1, 2003
Last modified: July 6, 2016
This is version 93 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.