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Protein
Submitted name:

Uncharacterized protein

Gene

vamp2

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Enzyme and pathway databases

ReactomeiR-DRE-181430. Norepinephrine Neurotransmitter Release Cycle.
R-DRE-210500. Glutamate Neurotransmitter Release Cycle.
R-DRE-264642. Acetylcholine Neurotransmitter Release Cycle.
R-DRE-421837. Clathrin derived vesicle budding.
R-DRE-432720. Lysosome Vesicle Biogenesis.
R-DRE-432722. Golgi Associated Vesicle Biogenesis.
R-DRE-888590. GABA synthesis, release, reuptake and degradation.

Names & Taxonomyi

Protein namesi
Submitted name:
Uncharacterized proteinImported
Submitted name:
Vesicle-associated membrane protein 2Imported
Gene namesi
Name:vamp2Imported
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
Proteomesi
  • UP000000437 Componenti: Chromosome 10

Organism-specific databases

ZFINiZDB-GENE-030131-8225. vamp2.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei89 – 10820HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

  • cleavage furrow Source: ZFIN
  • integral component of membrane Source: UniProtKB-KW
  • plasma membrane Source: ZFIN
  • SNARE complex Source: GO_Central
  • vesicle Source: ZFIN
Complete GO annotation...

Keywords - Cellular componenti

Membrane

Expressioni

Gene expression databases

BgeeiENSDARG00000056877.

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi7955.ENSDARP00000073910.

Structurei

3D structure databases

SMRiQ7SZZ5. Positions 19-86.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini25 – 8561V-SNARE coiled-coil homologyInterPro annotationAdd
BLAST

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG0860. Eukaryota.
COG5143. LUCA.
GeneTreeiENSGT00550000074449.
HOGENOMiHOG000042711.
HOVERGENiHBG006675.
KOiK13504.
OMAiERFQTTS.
OrthoDBiEOG091G0MPE.
PhylomeDBiQ7SZZ5.
TreeFamiTF313666.

Family and domain databases

Gene3Di1.10.3840.10. 1 hit.
InterProiIPR001388. Synaptobrevin.
IPR016444. Synaptobrevin/VAMP.
[Graphical view]
PfamiPF00957. Synaptobrevin. 1 hit.
[Graphical view]
PIRSFiPIRSF005409. Synaptobrevin_euk. 1 hit.
PRINTSiPR00219. SYNAPTOBREVN.
PROSITEiPS00417. SYNAPTOBREVIN. 1 hit.
PS50892. V_SNARE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q7SZZ5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSAPAGAPAP EGGNQAPPNL TSNRRLQQTQ AQVDEVVDIM RVNVDKVLER
60 70 80 90 100
DQKLSELDDR ADALQAGASQ FETSAAKLKN KYWWKNAKMM IILGVICVIV
110
LIIIIVYFST
Length:110
Mass (Da):12,128
Last modified:October 1, 2003 - v1
Checksum:iDF482474CC9816A0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL807389 Genomic DNA. No translation available.
BC059626 mRNA. Translation: AAH59626.1.
RefSeqiNP_956299.1. NM_200005.1.
UniGeneiDr.116682.

Genome annotation databases

EnsembliENSDART00000079454; ENSDARP00000073910; ENSDARG00000056877.
GeneIDi336281.
KEGGidre:336281.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL807389 Genomic DNA. No translation available.
BC059626 mRNA. Translation: AAH59626.1.
RefSeqiNP_956299.1. NM_200005.1.
UniGeneiDr.116682.

3D structure databases

SMRiQ7SZZ5. Positions 19-86.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi7955.ENSDARP00000073910.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSDART00000079454; ENSDARP00000073910; ENSDARG00000056877.
GeneIDi336281.
KEGGidre:336281.

Organism-specific databases

CTDi6844.
ZFINiZDB-GENE-030131-8225. vamp2.

Phylogenomic databases

eggNOGiKOG0860. Eukaryota.
COG5143. LUCA.
GeneTreeiENSGT00550000074449.
HOGENOMiHOG000042711.
HOVERGENiHBG006675.
KOiK13504.
OMAiERFQTTS.
OrthoDBiEOG091G0MPE.
PhylomeDBiQ7SZZ5.
TreeFamiTF313666.

Enzyme and pathway databases

ReactomeiR-DRE-181430. Norepinephrine Neurotransmitter Release Cycle.
R-DRE-210500. Glutamate Neurotransmitter Release Cycle.
R-DRE-264642. Acetylcholine Neurotransmitter Release Cycle.
R-DRE-421837. Clathrin derived vesicle budding.
R-DRE-432720. Lysosome Vesicle Biogenesis.
R-DRE-432722. Golgi Associated Vesicle Biogenesis.
R-DRE-888590. GABA synthesis, release, reuptake and degradation.

Gene expression databases

BgeeiENSDARG00000056877.

Family and domain databases

Gene3Di1.10.3840.10. 1 hit.
InterProiIPR001388. Synaptobrevin.
IPR016444. Synaptobrevin/VAMP.
[Graphical view]
PfamiPF00957. Synaptobrevin. 1 hit.
[Graphical view]
PIRSFiPIRSF005409. Synaptobrevin_euk. 1 hit.
PRINTSiPR00219. SYNAPTOBREVN.
PROSITEiPS00417. SYNAPTOBREVIN. 1 hit.
PS50892. V_SNARE. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ7SZZ5_DANRE
AccessioniPrimary (citable) accession number: Q7SZZ5
Entry historyi
Integrated into UniProtKB/TrEMBL: October 1, 2003
Last sequence update: October 1, 2003
Last modified: September 7, 2016
This is version 97 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.