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Protein
Submitted name:

Vesicle-associated membrane protein 2

Gene

vamp2

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

ReactomeiR-DRE-181429 Serotonin Neurotransmitter Release Cycle
R-DRE-181430 Norepinephrine Neurotransmitter Release Cycle
R-DRE-210500 Glutamate Neurotransmitter Release Cycle
R-DRE-212676 Dopamine Neurotransmitter Release Cycle
R-DRE-264642 Acetylcholine Neurotransmitter Release Cycle
R-DRE-421837 Clathrin derived vesicle budding
R-DRE-432720 Lysosome Vesicle Biogenesis
R-DRE-432722 Golgi Associated Vesicle Biogenesis
R-DRE-449836 Other interleukin signaling
R-DRE-8856825 Cargo recognition for clathrin-mediated endocytosis
R-DRE-8856828 Clathrin-mediated endocytosis
R-DRE-888590 GABA synthesis, release, reuptake and degradation

Names & Taxonomyi

Protein namesi
Submitted name:
Vesicle-associated membrane protein 2Imported
Gene namesi
Name:vamp2Imported
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
Proteomesi
  • UP000000437 Componenti: Chromosome 10

Organism-specific databases

ZFINiZDB-GENE-030131-8225 vamp2

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei89 – 108HelicalSequence analysisAdd BLAST20

Keywords - Cellular componenti

Membrane

Expressioni

Gene expression databases

BgeeiENSDARG00000056877

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi7955.ENSDARP00000073910

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini25 – 85V-SNARE coiled-coil homologyInterPro annotationAdd BLAST61

Keywords - Domaini

Coiled coilPROSITE-ProRule annotationSAAS annotation, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG0860 Eukaryota
COG5143 LUCA
GeneTreeiENSGT00550000074449
HOGENOMiHOG000042711
HOVERGENiHBG006675
KOiK13504
OMAiFVLITER
OrthoDBiEOG091G0MPE
TreeFamiTF313666

Family and domain databases

InterProiView protein in InterPro
IPR001388 Synaptobrevin
IPR016444 Synaptobrevin/VAMP
PfamiView protein in Pfam
PF00957 Synaptobrevin, 1 hit
PIRSFiPIRSF005409 Synaptobrevin_euk, 1 hit
PRINTSiPR00219 SYNAPTOBREVN
PROSITEiView protein in PROSITE
PS00417 SYNAPTOBREVIN, 1 hit
PS50892 V_SNARE, 1 hit

Sequencei

Sequence statusi: Complete.

Q7SZZ5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSAPAGAPAP EGGNQAPPNL TSNRRLQQTQ AQVDEVVDIM RVNVDKVLER
60 70 80 90 100
DQKLSELDDR ADALQAGASQ FETSAAKLKN KYWWKNAKMM IILGVICVIV
110
LIIIIVYFST
Length:110
Mass (Da):12,128
Last modified:October 1, 2003 - v1
Checksum:iDF482474CC9816A0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL807389 Genomic DNA No translation available.
BC059626 mRNA Translation: AAH59626.1
RefSeqiNP_956299.1, NM_200005.1
UniGeneiDr.116682

Genome annotation databases

EnsembliENSDART00000079454; ENSDARP00000073910; ENSDARG00000056877
GeneIDi336281
KEGGidre:336281

Similar proteinsi

Entry informationi

Entry nameiQ7SZZ5_DANRE
AccessioniPrimary (citable) accession number: Q7SZZ5
Entry historyiIntegrated into UniProtKB/TrEMBL: October 1, 2003
Last sequence update: October 1, 2003
Last modified: March 28, 2018
This is version 110 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
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Main funding by: National Institutes of Health