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Reviewed, UniProtKB/Swiss-Prot Q7SYV0 (SYFAB_XENLA)

Last modified June 16, 2009. Version 38. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

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Names and origin

Protein namesRecommended name:
    Phenylalanyl-tRNA synthetase alpha chain B
    EC=6.1.1.20
Alternative name(s):
    Phenylalanine--tRNA ligase alpha chain B
      Short name=PheRS
Gene names
Name: farsa-B
Synonyms: farsla-B
OrganismXenopus laevis (African clawed frog)
Taxonomic identifier8355 [NCBI]
Taxonomic lineageEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Amphibia › Batrachia › Anura › Mesobatrachia › Pipoidea › Pipidae › Xenopodinae › Xenopus › Xenopus

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Protein attributes

Sequence length499 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at transcript level.

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General annotation (Comments)

Catalytic activity

ATP + L-phenylalanine + tRNA(Phe) = AMP + diphosphate + L-phenylalanyl-tRNA(Phe).

Subunit structure

Tetramer of two alpha and two beta chains By similarity.

Subcellular location

Cytoplasm By similarity.

Sequence similarities

Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha chain type 2 subfamily.

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Ontologies

Keywords
   Biological processProtein biosynthesis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionAminoacyl-tRNA synthetase
Ligase
Gene Ontology (GO)
   Biological processphenylalanyl-tRNA aminoacylation

Inferred from electronic annotation. Source: InterPro

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

phenylalanine-tRNA ligase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

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Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Initiator methionine11Removed By similarity
Chain2 – 499498Phenylalanyl-tRNA synthetase alpha chain B
PRO_0000280453

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Sequences

Sequence LengthMass (Da)Tools
Q7SYV0-1 [UniParc].

Last modified October 1, 2003. Version 1.
Checksum: A632A4680B2C27C2

FASTA49956,750
        10         20         30         40         50         60 
MADNLLSEQL LQRLQDGDNK GVDTLELAAV LSVDHQQVVG AVKSLQCLGE IIEAEQRSSK 

        70         80         90        100        110        120 
KWELSSEGEE IAQVGSHEAR VFQSLPKEGL LQAELMKLPF AKVGFSKAMS NKWIRLDKAA 

       130        140        150        160        170        180 
AGGPCVYRVV ETIEDTVKEK LQLILKGRAD DVNEKDKNEL KKRKLVNEVT VKSYWVTKGS 

       190        200        210        220        230        240 
GFSTSITKQE TDLTPEMIAS GSWREKQFKG YNFNALGVMP ECGHLHPLLK VRTQFRQIFL 

       250        260        270        280        290        300 
EMGFTEMPTN NFIESSFWNF DALFQPQQHP ARDQHDTFFL QDPALATEFP MEYLERVKKV 

       310        320        330        340        350        360 
HSEGGYGSQG YKYDWSIHEA QKNILRTHTT AVSARMLYKL AHQKEFTPVK YFSIDRVFRN 

       370        380        390        400        410        420 
ETLDATHLAE FHQIEGVVAD RGLTLGNLMG VLKEFFHKLG ITKLRFKPAY NPYTEPSMEV 

       430        440        450        460        470        480 
FSYHEGLKKW VEVGNSGLFR PELLLPMGLP GDVNVLGWGL SLERPTMIRY GIKNIRELVG 

       490 
HKVNLQMVYD SPICRLDAC

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References

[1]NIH - Xenopus Gene Collection (XGC) project
Submitted (JUN-2003) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].

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Cross-references

Sequence databases

BC054256 mRNA. Translation: AAH54256.1.
RefSeqNP_001080851.1.
UniGeneXl.62819

3D structure databases

HSSPHSSP built from PDB template 1JJC based on UniProtKB P27001.
ModBaseSearch...

Genome annotation databases

GeneID380545.
KEGGxla:380545.

Phylogenomic databases

HOVERGENQ7SYV0.

Enzyme and pathway databases

BRENDA6.1.1.20. 648.

Family and domain databases

InterProIPR006195. aa-tRNA-synth_II_cons-reg.
IPR002319. Phe-tRNA-synth_IIc-rel.
IPR004529. Phe-tRNA-synth_IIc_asu.
IPR018157. Phe-tRNA-synth_IIc_C.
[Graphical view]
PANTHERPTHR11538. tRNA-synt_2d. 1 hit.
PfamPF01409. tRNA-synt_2d. 1 hit.
[Graphical view]
TIGRFAMsTIGR00468. pheS. 1 hit.
PROSITEPS50862. AA_TRNA_LIGASE_II. 1 hit.
[Graphical view]
ProtoNetSearch...

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Entry information

Entry nameSYFAB_XENLA
AccessionPrimary (citable) accession number: Q7SYV0
Entry history
Integrated into UniProtKB/Swiss-Prot: March 20, 2007
Last sequence update: October 1, 2003
Last modified: June 16, 2009
This is version 38 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectXenopus annotation project

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Relevant documents

Aminoacyl-tRNA synthetases

List of aminoacyl-tRNA synthetase entries

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents