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Q7SIE3

- Q7SIE3_BACAG

UniProt

Q7SIE3 - Q7SIE3_BACAG

Protein

Endo-1,4-beta-xylanase

Gene
N/A
Organism
Bacillus agaradhaerens (Bacillus agaradherans)
Status
Unreviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 65 (01 Oct 2014)
      Sequence version 1 (15 Dec 2003)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    Endohydrolysis of (1->4)-beta-D-xylosidic linkages in xylans.

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei94 – 941NucleophileImported
    Active sitei184 – 1841Proton donor/acceptorImported

    GO - Molecular functioni

    1. endo-1,4-beta-xylanase activity Source: UniProtKB-EC

    GO - Biological processi

    1. xylan catabolic process Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    GlycosidaseUniRule annotation, Hydrolase

    Keywords - Biological processi

    Carbohydrate metabolism, Polysaccharide degradation, Xylan degradationUniRule annotation

    Enzyme and pathway databases

    UniPathwayiUPA00114.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Endo-1,4-beta-xylanaseUniRule annotation (EC:3.2.1.8UniRule annotation)
    OrganismiBacillus agaradhaerens (Bacillus agaradherans)Imported
    Taxonomic identifieri76935 [NCBI]
    Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus

    PTM / Processingi

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei1 – 11Pyrrolidone carboxylic acid
    Modified residuei1 – 11Pyrrolidonecarboxylic acidImported

    Structurei

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    EntryMethodResolution (Å)ChainPositionsPDBsum
    1H4GX-ray1.10A/B2-207[»]
    1QH6X-ray2.00A/B1-207[»]
    1QH7X-ray1.78A/B1-207[»]
    2F6BX-ray2.80A/B2-206[»]
    2NQYX-ray2.40A/B2-206[»]
    ProteinModelPortaliQ7SIE3.
    SMRiQ7SIE3. Positions 1-207.
    ModBaseiSearch...
    MobiDBiSearch...

    Miscellaneous databases

    EvolutionaryTraceiQ7SIE3.

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the glycosyl hydrolase 11 (cellulase G) family.UniRule annotation

    Family and domain databases

    Gene3Di2.60.120.180. 1 hit.
    InterProiIPR008985. ConA-like_lec_gl_sf.
    IPR001137. Glyco_hydro_11.
    IPR013319. Glyco_hydro_11/12.
    IPR018208. Glyco_hydro_11_AS.
    [Graphical view]
    PfamiPF00457. Glyco_hydro_11. 1 hit.
    [Graphical view]
    PRINTSiPR00911. GLHYDRLASE11.
    SUPFAMiSSF49899. SSF49899. 1 hit.
    PROSITEiPS00776. GLYCOSYL_HYDROL_F11_1. 1 hit.
    PS00777. GLYCOSYL_HYDROL_F11_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q7SIE3-1 [UniParc]FASTAAdd to Basket

    « Hide

    QIVTDNSIGN HDGYDYEFWK DSGGSGTMIL NHGGTFSAQW NNVNNILFRK    50
    GKKFNETQTH QQVGNMSINY GANFQPNGNA YLCVYGWTVD PLVEYYIVDS 100
    WGNWRPPGAT PKGTITVDGG TYDIYETLRV NQPSIKGIAT FKQYWSVRRS 150
    KRTSGTISVS NHFRAWENLG MNMGKMYEVA LTVEGYQSSG SANVYSNTLR 200
    INGNPLS 207
    Length:207
    Mass (Da):23,152
    Last modified:December 15, 2003 - v1
    Checksum:iC498EF0D0A085D0B
    GO

    Cross-referencesi

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    Entry Method Resolution (Å) Chain Positions PDBsum
    1H4G X-ray 1.10 A/B 2-207 [» ]
    1QH6 X-ray 2.00 A/B 1-207 [» ]
    1QH7 X-ray 1.78 A/B 1-207 [» ]
    2F6B X-ray 2.80 A/B 2-206 [» ]
    2NQY X-ray 2.40 A/B 2-206 [» ]
    ProteinModelPortali Q7SIE3.
    SMRi Q7SIE3. Positions 1-207.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Enzyme and pathway databases

    UniPathwayi UPA00114 .

    Miscellaneous databases

    EvolutionaryTracei Q7SIE3.

    Family and domain databases

    Gene3Di 2.60.120.180. 1 hit.
    InterProi IPR008985. ConA-like_lec_gl_sf.
    IPR001137. Glyco_hydro_11.
    IPR013319. Glyco_hydro_11/12.
    IPR018208. Glyco_hydro_11_AS.
    [Graphical view ]
    Pfami PF00457. Glyco_hydro_11. 1 hit.
    [Graphical view ]
    PRINTSi PR00911. GLHYDRLASE11.
    SUPFAMi SSF49899. SSF49899. 1 hit.
    PROSITEi PS00776. GLYCOSYL_HYDROL_F11_1. 1 hit.
    PS00777. GLYCOSYL_HYDROL_F11_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Catalysis and specificity in enzymatic glycoside hydrolysis: a 2,5B conformation for the glycosyl-enzyme intermediate revealed by the structure of the Bacillus agaradhaerens family 11 xylanase."
      Sabini E., Sulzenbacher G., Dauter M., Dauter Z., Jorgensen P.L., Schulein M., Dupont C., Davies G.J., Wilson K.S.
      Chem. Biol. 6:483-492(1999) [PubMed] [Europe PMC] [Abstract]
      Cited for: X-RAY CRYSTALLOGRAPHY (1.10 ANGSTROMS) OF 2-207, ACTIVE SITE, AND PYRROLIDONECARBOXYLIC ACID AT GLN-1.
    2. "Structural and active site modification studies implicate Glu, Trp and Arg in the activity of xylanase from alkalophilic Bacillus sp. (NCL 87-6-10)."
      Balakrishnan H., Satyanarayana L., Gaikward S., Suresh C.G.
      Submitted (NOV-2005) to the PDB data bank
      Cited for: X-RAY CRYSTALLOGRAPHY (2.80 ANGSTROMS) OF 2-206.
    3. "Crystal structure of alkaline thermophlic xylanase from Bacillus sp. (NCL 86-6-10) with complex xylotriose: Xylotriose cleaved to xylobiose and xylose."
      Satyanarayana L., Gaikwad S.M., Balakrishnan H., Suresh C.G.
      Submitted (NOV-2006) to the PDB data bank
      Cited for: X-RAY CRYSTALLOGRAPHY (2.40 ANGSTROMS) OF 2-206.

    Entry informationi

    Entry nameiQ7SIE3_BACAG
    AccessioniPrimary (citable) accession number: Q7SIE3
    Entry historyi
    Integrated into UniProtKB/TrEMBL: December 15, 2003
    Last sequence update: December 15, 2003
    Last modified: October 1, 2014
    This is version 65 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    3D-structureImported

    External Data

    Dasty 3