Q7SIE1 (Q7SIE1_LACBR) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names	Submitted name: Hydrolase PDB 1H54
Organism	Lactobacillus brevis PDB 1H54
Taxonomic identifier	1580 [NCBI]
Taxonomic lineage	cellular organisms › Bacteria › Firmicutes › Bacilli › Lactobacillales › Lactobacillaceae › Lactobacillus

Protein attributes

Sequence length	754 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

Ontologies

Keywords
Technical term	3D-structure PDB 1H54
Gene Ontology (GO)
Biological_process	carbohydrate metabolic process Inferred from electronic annotation. Source: InterPro
Molecular_function	carbohydrate binding Inferred from electronic annotation. Source: InterPro catalytic activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Active site	487	1	Proton donor/acceptor PDB 1H54

Sequences

	Sequence		Length	Mass (Da)
	Q7SIE1 [UniParc]. Last modified December 15, 2003. Version 1. Checksum: F959BA54215C9D28	FASTA	754	85,737
	10 20 30 40 50 60 MKRIFEVQPW NVITHTFDPK DKRLQESMTS LGNGYMGMRG DFEEGYSGDS LQGIYLGGVW 70 80 90 100 110 120 YPDKTRVGWW KNGYPKYFGK VVNAVNFIKL PIEINGEPVD LAKDKISDFT LDLDMHQGVL 130 140 150 160 170 180 NRSFVVERGA VRVALNFQRF LSVAQPELSV QKVTVKNLSD AEVDVTLKPS IDADVMNEEA 190 200 210 220 230 240 NYDERFWDVL ATDQQADRGS IVAKTTPNPF GTPRFTSGME MRLVTDLKNV AITQPNEKEV 250 260 270 280 290 300 TTAYTGKLAP QASAELEKRV IVVTSRDYDT QESLTAAMHQ LSDKVAQSSY EDLLNAHTAI 310 320 330 340 350 360 WAQRWEKSDV VIKGDDESQQ GIRFNLFQLF STYYGEDARL NIGPKGFTGE KYGGATYWDT 370 380 390 400 410 420 EAFAFPVYLG ITDPKVTRNL LMYRYKQLDG AYINAQEQGL KGALFPMVTF DGIECHNEWE 430 440 450 460 470 480 ITFEEIHRNG DIAFAIYNYT RYTGDDSYVL HEGAKVLTEI SRFWADRVHF SKRNNQYMIH 490 500 510 520 530 540 GVTGADEYEN NVDNNWDTNM LAQWTLKYTL EILGKVDQDT AKQLDVSDEE KTKWQDIVDR 550 560 570 580 590 600 MYLPYDKDLN IFVQHDGFLD KDIEPVSSIP ADQRPINQNW SWDKILRSPY IKQGDVLQGI 610 620 630 640 650 660 WDFIDDYTPE QKKANFDFYE PLTVHESSLS PAIHSVLAAD LHYEDKAVEL YSRTARLDLD 670 680 690 700 710 720 NYNNDTTDGL HITSMTGAWI AVVQGFAGMR VRDGQLHYAP FLPKTWTSYT FRQVFRDRLI 730 740 750 EVSVHADGPH FKLLSGEPLT IDVAGAAAAA AAAA

References

[1]	"Crystal structure of maltose phosphorylase from Lactobacillus brevis: unexpected evolutionary relationship with glucoamylases." Egloff M.P., Uppenberg J., Haalck L., van Tilbeurgh H. Structure 9:689-697(2001) [PubMed] [Europe PMC] [Abstract] Cited for: X-RAY CRYSTALLOGRAPHY (2.15 ANGSTROMS), ACTIVE SITE.
+	Additional computationally mapped references.

Cross-references

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
1H54	X-ray	2.15	A/B	1-754	[»]

ProteinModelPortal

Q7SIE1.

SMR

Q7SIE1. Positions 1-743.

ModBase

Search...

Protein family/group databases

CAZy

GH65. Glycoside Hydrolase Family 65.

Protocols and materials databases

StructuralBiologyKnowledgebase

Search...

Enzyme and pathway databases

BioCyc

MetaCyc:MONOMER-13019.

Family and domain databases

Gene3D

1.50.10.10. 1 hit.
2.70.98.40. 1 hit.

InterPro

IPR008928. 6-hairpin_glycosidase-like.
IPR012341. 6hp_glycosidase.
IPR011013. Gal_mutarotase_SF_dom.
IPR005194. Glyco_hydro_65_C.
IPR005195. Glyco_hydro_65_M.
IPR005196. Glyco_hydro_65_N.
IPR017045. Malt_Pase/Glycosyl_Hdrlase.
[Graphical view]

Pfam

PF03633. Glyco_hydro_65C. 1 hit.
PF03632. Glyco_hydro_65m. 1 hit.
PF03636. Glyco_hydro_65N. 1 hit.
[Graphical view]

PIRSF

PIRSF036289. Glycosyl_hydrolase_malt_phosph. 1 hit.

SUPFAM

SSF74650. Gal_mut_like. 1 hit.
SSF48208. Glyco_trans_6hp. 1 hit.

ProtoNet

Search...

Other

EvolutionaryTrace

Q7SIE1.

Entry information

Entry name

Q7SIE1_LACBR

Accession

Primary (citable) accession number: Q7SIE1

Entry history

Integrated into UniProtKB/TrEMBL:	December 15, 2003
Last sequence update:	December 15, 2003
Last modified:	April 3, 2013
This is version 40 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)