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Q7SGY1 (ALO_NEUCR) Reviewed, UniProtKB/Swiss-Prot

Last modified March 19, 2014. Version 78. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Putative D-arabinono-1,4-lactone oxidase

Short name=ALO
EC=1.1.3.37
Alternative name(s):
L-galactono-gamma-lactone oxidase
Gene names
Name:alo-1
ORF Names:NCU03188
OrganismNeurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987) [Reference proteome]
Taxonomic identifier367110 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaPezizomycotinaSordariomycetesSordariomycetidaeSordarialesSordariaceaeNeurospora

Protein attributes

Sequence length556 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

D-arabinono-1,4-lactone + O2 = dehydro-D-arabinono-1,4-lactone + H2O2.

Cofactor

FAD By similarity.

Pathway

Cofactor biosynthesis; D-erythroascorbate biosynthesis; dehydro-D-arabinono-1,4-lactone from D-arabinose: step 2/2.

Subcellular location

Mitochondrion membrane By similarity. Note: Membrane-embedded By similarity.

Sequence similarities

Belongs to the oxygen-dependent FAD-linked oxidoreductase family.

Contains 1 FAD-binding PCMH-type domain.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 556556Putative D-arabinono-1,4-lactone oxidase
PRO_0000128168

Regions

Domain47 – 217171FAD-binding PCMH-type

Amino acid modifications

Modified residue841Pros-8alpha-FAD histidine By similarity

Sequences

Sequence LengthMass (Da)Tools
Q7SGY1 [UniParc].

Last modified December 15, 2003. Version 1.
Checksum: 7E8FDCCF866F10ED

FASTA55662,600
        10         20         30         40         50         60 
MATESNPALA SLPSNVREII ELASQRDGGI PFRAKTAHVH RTWAGTFTSL PELYIQPESV 

        70         80         90        100        110        120 
SEIQKVVRLA RHARRRVTTT GCGHSPSDIT CTSSWLVNLD NFNKVISVDH LTGLVVVQAG 

       130        140        150        160        170        180 
IRLYQLSDEL DRRGLALPSL GSINEQSIAG AISTGTHGSG IKHGLVGESI TELKITLANG 

       190        200        210        220        230        240 
ETLSCSPEDK PDLFRAALIS LGALGIITEV TFKAVPAFSL AWSQAIDSDK RIFEKWEKDL 

       250        260        270        280        290        300 
WSQAEFVRIW WFPYMRRAAV WTANVVDPVD LKTGAVKHRE PPTSYYDSWL GYYVYHNLLA 

       310        320        330        340        350        360 
LSRWIPRITP WIEWFVFGMQ YGFKNGEVTR IGAVQPSQKA FLLNCLYSQS VNEWAIPLHK 

       370        380        390        400        410        420 
GPEALQRLGA WLQNLKPGDP GYVEHGIPYS AEGLWVHSPV EVRASDSTVY TSREANTRPF 

       430        440        450        460        470        480 
LDPTQSDGPT LYLNAIMYRP YHREPTYNAT ERYYLGFEWL MRELGGKPHW AKTFTATQAD 

       490        500        510        520        530        540 
LARWYGDDFQ RWGAVRESVD PEGMFVGPWH RRYLLEPLQR DRLLPLEEIQ QTTKKVPARQ 

       550 
GGGIEVIGIQ NLVAPN 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CM002236 Genomic DNA. Translation: EAA36052.1.
RefSeqXP_965288.1. XM_960195.1.

3D structure databases

ProteinModelPortalQ7SGY1.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING5141.NCU03188.1.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiEFNCRT00000002860; EFNCRP00000002860; EFNCRG00000002857.
GeneID3881437.
KEGGncr:NCU03188.

Phylogenomic databases

eggNOGCOG0277.
HOGENOMHOG000204635.
KOK00107.
OMAMDCLFSQ.
OrthoDBEOG7JX3CZ.

Enzyme and pathway databases

UniPathwayUPA00771; UER00766.

Family and domain databases

Gene3D3.30.43.10. 1 hit.
3.30.465.10. 1 hit.
InterProIPR007173. ALO.
IPR016169. CO_DH_flavot_FAD-bd_sub2.
IPR016166. FAD-bd_2.
IPR016167. FAD-bd_2_sub1.
IPR010031. FAD_lactone_oxidase.
IPR023595. LGO_GLO.
IPR006094. Oxid_FAD_bind_N.
IPR006093. Oxy_OxRdtase_FAD_BS.
[Graphical view]
PfamPF04030. ALO. 1 hit.
PF01565. FAD_binding_4. 1 hit.
[Graphical view]
PIRSFPIRSF000136. LGO_GLO. 1 hit.
SUPFAMSSF56176. SSF56176. 1 hit.
TIGRFAMsTIGR01678. FAD_lactone_ox. 1 hit.
PROSITEPS51387. FAD_PCMH. 1 hit.
PS00862. OX2_COVAL_FAD. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameALO_NEUCR
AccessionPrimary (citable) accession number: Q7SGY1
Entry history
Integrated into UniProtKB/Swiss-Prot: November 23, 2004
Last sequence update: December 15, 2003
Last modified: March 19, 2014
This is version 78 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways