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Protein

Pescadillo homolog

Gene

nop7

Organism
Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processRibosome biogenesis, rRNA processing

Names & Taxonomyi

Protein namesi
Recommended name:
Pescadillo homologUniRule annotation
Alternative name(s):
Nucleolar protein 7 homologUniRule annotation
Gene namesi
Name:nop7
ORF Names:G17B7.070, NCU00925
OrganismiNeurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)
Taxonomic identifieri367110 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaSordariomycetesSordariomycetidaeSordarialesSordariaceaeNeurospora
Proteomesi
  • UP000001805 Componenti: Chromosome 1, Linkage Group I

Organism-specific databases

EuPathDBiFungiDB:NCU00925

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003704981 – 663Pescadillo homologAdd BLAST663

Proteomic databases

PRIDEiQ7SFC2

Interactioni

Subunit structurei

Component of the NOP7 complex, composed of erb1, nop7 and ytm1. The complex is held together by erb1, which interacts with nop7 via its N-terminal domain and with ytm1 via a high-affinity interaction between the seven-bladed beta-propeller domains of the 2 proteins. The NOP7 complex associates with the 66S pre-ribosome.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliQ7SFC2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini361 – 477BRCTUniRule annotationAdd BLAST117

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili501 – 663UniRule annotationAdd BLAST163

Sequence similaritiesi

Belongs to the pescadillo family.UniRule annotation

Keywords - Domaini

Coiled coil

Phylogenomic databases

HOGENOMiHOG000006022
InParanoidiQ7SFC2
KOiK14843
OrthoDBiEOG092C1M1S

Family and domain databases

CDDicd00027 BRCT, 1 hit
Gene3Di3.40.50.10190, 1 hit
HAMAPiMF_03028 Pescadillo, 1 hit
InterProiView protein in InterPro
IPR001357 BRCT_dom
IPR036420 BRCT_dom_sf
IPR010613 PES
PANTHERiPTHR12221 PTHR12221, 1 hit
PfamiView protein in Pfam
PF06732 Pescadillo_N, 1 hit
SUPFAMiSSF52113 SSF52113, 1 hit
PROSITEiView protein in PROSITE
PS50172 BRCT, 1 hit

Sequencei

Sequence statusi: Complete.

Q7SFC2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPKIKKKGQA GAAKNYITRT QAVKKLQLSL PDFRKLCIWK GIYPREPRNK
60 70 80 90 100
KKVSKSATAS TTFYYTKDIQ YLLHEPLLQK FRDQKVLEKK ISRALGRGDV
110 120 130 140 150
SDAARFERHA ARPEATGKPR YTLNHVIRER YPTFNDALRD LDDCLSMLFL
160 170 180 190 200
FANLPSTSAV PAKMIARCER LCLEFQHYLI VSHSLRKSFL SIKGIYYQAN
210 220 230 240 250
IQGEDILWLV PYKFNQRIVG DVDFRIMGTF VEFYMTLLGF VNYRLYSSIG
260 270 280 290 300
LKYPPKFDQL KDENGAELGA FSLEGVNMAT QGETKAVTNG EEQQQGPDPK
310 320 330 340 350
VQAEVDKIIK QLKEDESKSD ETAEEDAEAD DEEKPTDSID KFEPVAPGGD
360 370 380 390 400
VLPQPAYSSS DPSQLFANFT FYLSRETPRQ PLEFILRAFG CKRIGWDSVL
410 420 430 440 450
GEGAFTNDES DPSITHHIID RPVVQAATNE DGDGEDNQTA QKVGPNQRYP
460 470 480 490 500
GRIYVQPQWV WDCVNDEELK SPELYAPGAA LPPHLSPFVK AAPGQYDPTL
510 520 530 540 550
PLEAQQTEAE AIEADLEDAE KGNAEDGSDV ENDMDVDEAE DDEEEEEGDE
560 570 580 590 600
EDAEEAEEED AEEDEEESKT LQRQLELEAE LQGKKVQNTK VDSKTKAKLE
610 620 630 640 650
QRKALEKKAR EEAEDLERAK GMLSKKKRKL FEQMQYTNNK KSAQDEKLRA
660
KRRKLEKEKA QKA
Length:663
Mass (Da):75,293
Last modified:December 15, 2003 - v1
Checksum:iC33A1DB1C8E18114
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX842638 Genomic DNA Translation: CAE76578.1
CM002236 Genomic DNA Translation: EAA35515.1
RefSeqiXP_964751.1, XM_959658.2

Genome annotation databases

EnsemblFungiiEAA35515; EAA35515; NCU00925
GeneIDi3880904
KEGGincr:NCU00925

Similar proteinsi

Entry informationi

Entry nameiPESC_NEUCR
AccessioniPrimary (citable) accession number: Q7SFC2
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 5, 2009
Last sequence update: December 15, 2003
Last modified: May 23, 2018
This is version 91 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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