Q7SDH9 (PSF1_NEUCR) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
DNA replication complex GINS protein psf-1

Gene names

Name:	psf-1
ORF Names:	NCU02631

Organism

Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987) [Reference proteome]

Taxonomic identifier

367110 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Fungi › Dikarya › Ascomycota › saccharomyceta › Pezizomycotina › leotiomyceta › sordariomyceta › Sordariomycetes › Sordariomycetidae › Sordariales › Sordariaceae › Neurospora › Neurospora crassa

Protein attributes

Sequence length	216 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	The GINS complex plays an essential role in the initiation of DNA replication By similarity.
Subunit structure	Component of the GINS complex which is a heterotetramer of sld-5, psf-1, psf-2 and psf-3 By similarity.
Subcellular location	Nucleus By similarity.
Sequence similarities	Belongs to the GINS1/PSF1 family.

Ontologies

Keywords
Biological process	DNA replication
Cellular component	Nucleus
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	DNA replication Inferred from electronic annotation. Source: UniProtKB-KW
Cellular_component	nucleus Inferred from electronic annotation. Source: UniProtKB-SubCell
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 216	216	DNA replication complex GINS protein psf-1		PRO_0000278404

Sequences

	Sequence		Length	Mass (Da)
	Q7SDH9 [UniParc]. Last modified December 15, 2003. Version 1. Checksum: 88E1AE3394567079	FASTA	216	24,153
	10 20 30 40 50 60 MPMYGDLGNK LVQHAKRTQN LSHLPPYQTE LVRAVAREIR DLDKDVASLL EPFQGSFDPS 70 80 90 100 110 120 AEQATACTLL VNHLSMRRNK RCLLAYHRIR TDKLEELVWN GADILDLAGQ TTGGPKGVTE 130 140 150 160 170 180 GNEGGGTTSS LSPQEEDYFR QFGDLLALYK GQWTDIDLTG SLEPPRDLFI DVRVLKDAGE 190 200 210 IQTEYGAINL TKNSQFYVRQ GDVERLIVQG YLQKLG

References

[1]

"The genome sequence of the filamentous fungus Neurospora crassa." Galagan J.E., Calvo S.E., Borkovich K.A., Selker E.U., Read N.D., Jaffe D.B., FitzHugh W., Ma L.-J., Smirnov S., Purcell S., Rehman B., Elkins T., Engels R., Wang S., Nielsen C.B., Butler J., Endrizzi M., Qui D. , Ianakiev P., Bell-Pedersen D., Nelson M.A., Werner-Washburne M., Selitrennikoff C.P., Kinsey J.A., Braun E.L., Zelter A., Schulte U., Kothe G.O., Jedd G., Mewes H.-W., Staben C., Marcotte E., Greenberg D., Roy A., Foley K., Naylor J., Stange-Thomann N., Barrett R., Gnerre S., Kamal M., Kamvysselis M., Mauceli E.W., Bielke C., Rudd S., Frishman D., Krystofova S., Rasmussen C., Metzenberg R.L., Perkins D.D., Kroken S., Cogoni C., Macino G., Catcheside D.E.A., Li W., Pratt R.J., Osmani S.A., DeSouza C.P.C., Glass N.L., Orbach M.J., Berglund J.A., Voelker R., Yarden O., Plamann M., Seiler S., Dunlap J.C., Radford A., Aramayo R., Natvig D.O., Alex L.A., Mannhaupt G., Ebbole D.J., Freitag M., Paulsen I., Sachs M.S., Lander E.S., Nusbaum C., Birren B.W. Nature 422:859-868(2003) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AABX02000006 Genomic DNA. Translation: EAA34820.1.
RefSeq	XP_964056.1. XM_958963.1.
3D structure databases
ProteinModelPortal	Q7SDH9.
ModBase	Search...
Protein-protein interaction databases
STRING	5141.NCU02631.1.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblFungi	EFNCRT00000002169; EFNCRP00000002169; EFNCRG00000002166.
GeneID	3880205.
KEGG	ncr:NCU02631.
Phylogenomic databases
eggNOG	COG5230.
HOGENOM	HOG000192102.
KO	K10732.
OrthoDB	EOG4W9ND7.
Family and domain databases
InterPro	IPR021151. GINS_complex. IPR005339. GINS_Psf1. [Graphical view]
PANTHER	PTHR12914. PTHR12914. 1 hit.
Pfam	PF05916. Sld5. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

PSF1_NEUCR

Accession

Primary (citable) accession number: Q7SDH9

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 20, 2007
Last sequence update:	December 15, 2003
Last modified:	April 3, 2013
This is version 53 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Fungal Protein Annotation Program