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Q7SCH4

- Q7SCH4_NEUCR

UniProt

Q7SCH4 - Q7SCH4_NEUCR

Protein

Glutamate decarboxylase

Gene

NCU06803

Organism
Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 67 (01 Oct 2014)
      Sequence version 2 (23 Oct 2007)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    L-glutamate = 4-aminobutanoate + CO2.UniRule annotation

    Cofactori

    Pyridoxal phosphate.UniRule annotation

    GO - Molecular functioni

    1. glutamate decarboxylase activity Source: InterPro
    2. pyridoxal phosphate binding Source: InterPro

    GO - Biological processi

    1. glutamate metabolic process Source: InterPro

    Keywords - Molecular functioni

    DecarboxylaseUniRule annotation, Lyase

    Keywords - Ligandi

    Pyridoxal phosphateUniRule annotation

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Glutamate decarboxylaseUniRule annotation (EC:4.1.1.15UniRule annotation)
    Gene namesi
    ORF Names:NCU06803Imported
    OrganismiNeurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)Imported
    Taxonomic identifieri367110 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaSordariomycetesSordariomycetidaeSordarialesSordariaceaeNeurospora
    ProteomesiUP000001805: Chromosome 6, Linkage Group II

    PTM / Processingi

    Proteomic databases

    PRIDEiQ7SCH4.

    Interactioni

    Protein-protein interaction databases

    STRINGi5141.NCU06803.1.

    Structurei

    3D structure databases

    ProteinModelPortaliQ7SCH4.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the group II decarboxylase family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0076.
    HOGENOMiHOG000070228.
    KOiK01580.
    OMAiMIGRLFN.
    OrthoDBiEOG7P2Z22.

    Family and domain databases

    Gene3Di3.40.640.10. 1 hit.
    InterProiIPR010107. Glutamate_decarboxylase.
    IPR002129. PyrdxlP-dep_de-COase.
    IPR015424. PyrdxlP-dep_Trfase.
    IPR015421. PyrdxlP-dep_Trfase_major_sub1.
    [Graphical view]
    PfamiPF00282. Pyridoxal_deC. 1 hit.
    [Graphical view]
    SUPFAMiSSF53383. SSF53383. 1 hit.
    TIGRFAMsiTIGR01788. Glu-decarb-GAD. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q7SCH4-1 [UniParc]FASTAAdd to Basket

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    MVHLTIIPKE DEIRDGLDIP LTGALKAVHL QLANDEDRFT TSVYGSKFAA    50
    ADLPRHEMPD EEMPKEVAYR MIKDELSLDG NPLLNLASFV TTYMEEEAEK 100
    LMTESLPKNF IDYEEYPQTA DIQNRCVSMI GRLFNAPVKD AEASSAVGTS 150
    SVGSSEAIML GVLAMKKRWK NKRIAEGKPA DKPNLIMSSA VQVCWEKATR 200
    YFEVEEKFVY CTPDRYVIDP KETVDLVDEN TIGICCILGT TYTGEYEDVK 250
    AVNDLLVERG LDTPIHVDAA SGGFVAPFVV PDLEWDFRLK NVVSINVSGH 300
    KYGLVYPGVG WVVWRSAEYL PQELVFNINY LGADQASFTL NFSKGASQVI 350
    GQYYQLIRLG KHGYRAIMSN LTRTADYLAE SLAALGFIIM SQKSGQGLPL 400
    VAFRLKEDPD RTYDEFALAH QLRVRGWIVP AYTMAPKTEG LKMLRIVVRE 450
    DFSRNRCDGL ISDIRSCQGI LEQMDKETVK KQQEFIHKHH VVSGKASHNH 500
    PKYHKEKHSL QGKTGKTHSI C 521
    Length:521
    Mass (Da):58,556
    Last modified:October 23, 2007 - v2
    Checksum:i438A83ABD96ED0EB
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CM002237 Genomic DNA. Translation: EAA34408.2.
    RefSeqiXP_963644.2. XM_958551.2.

    Genome annotation databases

    EnsemblFungiiEFNCRT00000006865; EFNCRP00000006856; EFNCRG00000006853.
    GeneIDi3879813.
    KEGGincr:NCU06803.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CM002237 Genomic DNA. Translation: EAA34408.2 .
    RefSeqi XP_963644.2. XM_958551.2.

    3D structure databases

    ProteinModelPortali Q7SCH4.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 5141.NCU06803.1.

    Proteomic databases

    PRIDEi Q7SCH4.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblFungii EFNCRT00000006865 ; EFNCRP00000006856 ; EFNCRG00000006853 .
    GeneIDi 3879813.
    KEGGi ncr:NCU06803.

    Phylogenomic databases

    eggNOGi COG0076.
    HOGENOMi HOG000070228.
    KOi K01580.
    OMAi MIGRLFN.
    OrthoDBi EOG7P2Z22.

    Family and domain databases

    Gene3Di 3.40.640.10. 1 hit.
    InterProi IPR010107. Glutamate_decarboxylase.
    IPR002129. PyrdxlP-dep_de-COase.
    IPR015424. PyrdxlP-dep_Trfase.
    IPR015421. PyrdxlP-dep_Trfase_major_sub1.
    [Graphical view ]
    Pfami PF00282. Pyridoxal_deC. 1 hit.
    [Graphical view ]
    SUPFAMi SSF53383. SSF53383. 1 hit.
    TIGRFAMsi TIGR01788. Glu-decarb-GAD. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "The genome sequence of the filamentous fungus Neurospora crassa."
      Galagan J.E., Calvo S.E., Borkovich K.A., Selker E.U., Read N.D., Jaffe D.B., FitzHugh W., Ma L.-J., Smirnov S., Purcell S., Rehman B., Elkins T., Engels R., Wang S., Nielsen C.B., Butler J., Endrizzi M., Qui D.
      , Ianakiev P., Bell-Pedersen D., Nelson M.A., Werner-Washburne M., Selitrennikoff C.P., Kinsey J.A., Braun E.L., Zelter A., Schulte U., Kothe G.O., Jedd G., Mewes H.-W., Staben C., Marcotte E., Greenberg D., Roy A., Foley K., Naylor J., Stange-Thomann N., Barrett R., Gnerre S., Kamal M., Kamvysselis M., Mauceli E.W., Bielke C., Rudd S., Frishman D., Krystofova S., Rasmussen C., Metzenberg R.L., Perkins D.D., Kroken S., Cogoni C., Macino G., Catcheside D.E.A., Li W., Pratt R.J., Osmani S.A., DeSouza C.P.C., Glass N.L., Orbach M.J., Berglund J.A., Voelker R., Yarden O., Plamann M., Seiler S., Dunlap J.C., Radford A., Aramayo R., Natvig D.O., Alex L.A., Mannhaupt G., Ebbole D.J., Freitag M., Paulsen I., Sachs M.S., Lander E.S., Nusbaum C., Birren B.W.
      Nature 422:859-868(2003) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987Imported.

    Entry informationi

    Entry nameiQ7SCH4_NEUCR
    AccessioniPrimary (citable) accession number: Q7SCH4
    Entry historyi
    Integrated into UniProtKB/TrEMBL: December 15, 2003
    Last sequence update: October 23, 2007
    Last modified: October 1, 2014
    This is version 67 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Caution

    The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3