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Q7SBD4 (EIF3C_NEUCR) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 69. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Eukaryotic translation initiation factor 3 subunit C

Short name=eIF3c
Alternative name(s):
Eukaryotic translation initiation factor 3 93 kDa subunit homolog
Short name=eIF3 p93
Translation initiation factor eIF3, p93 subunit homolog
Gene names
Name:nip-1
ORF Names:NCU07831
OrganismNeurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987) [Reference proteome]
Taxonomic identifier367110 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaPezizomycotinaSordariomycetesSordariomycetidaeSordarialesSordariaceaeNeurospora

Protein attributes

Sequence length872 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome By similarity. HAMAP-Rule MF_03002

Subunit structure

Component of the eukaryotic translation initiation factor 3 (eIF-3) complex By similarity.

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_03002.

Sequence similarities

Belongs to the eIF-3 subunit C family.

Contains 1 PCI domain.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 872872Eukaryotic translation initiation factor 3 subunit C HAMAP-Rule MF_03002
PRO_0000364287

Regions

Domain654 – 784131PCI

Sequences

Sequence LengthMass (Da)Tools
Q7SBD4 [UniParc].

Last modified December 15, 2003. Version 1.
Checksum: 38611B9B0CC93EA1

FASTA87298,399
        10         20         30         40         50         60 
MSRFFRGGDD SSTDSSSEEE EVYTSEEEEE KVQAEDESSS EEESDEEESD EESSSDEEEG 

        70         80         90        100        110        120 
TKKKGASRFL QSDDESEEEE EEQSDDEATT KVKSAKDKRF DELESTISQI QNGQKINDWS 

       130        140        150        160        170        180 
LIANEFDKLN RQVVKLQDGS KAPKSYIKAI ADLEDFMNET LAKQKVTPKK MNATNARGLN 

       190        200        210        220        230        240 
AVKQRIRKNN KEYQTQIDAY RKDADAFMES DDEVAAPKVV SKVRFEAPVV SAEQQEEDDK 

       250        260        270        280        290        300 
GFSTVDSRGK VVQYTPESIL KHLRAIIESR GKKNTDRLEQ IKVMETLNKV VPITPYQKIR 

       310        320        330        340        350        360 
VLQTLISARF DLGAGGAAQM PLDQWKAAER DLASLLEILE KEKDHVVVEG AEEWDDDDKL 

       370        380        390        400        410        420 
PTIPEGEKYL KVPGSVVSLI ERLDDELTRS LQAIDPHTSE YIDRLTDEGS LYNTIFRGLL 

       430        440        450        460        470        480 
YYEHLRKDAS LEVPQESLNR IIQRRLDHVY YKPAQVVKIL EENAWKQVSA EADSEITPRS 

       490        500        510        520        530        540 
QSGDAGKLIN ILSNYLFENS EGIIRARAML CQIYFLALHD EYYKSRDLML TSHLQETIAN 

       550        560        570        580        590        600 
FDIATQILYN RTLVQVGLCA FRKGLVYDAQ NTLQEICGSG RQKELLAQGV MIQRYSQVTP 

       610        620        630        640        650        660 
EQERLEKQRQ LPFHMHINLE LLECVYLTCS MLLEIPLLAQ TGSSPDVKKR IISKTYRRML 

       670        680        690        700        710        720 
EYHERQIFTG PPENTRDHVM QASKALAAGE WKKATDFIHS IKIWDLMPNT EGIKTMLAKQ 

       730        740        750        760        770        780 
IQEEGLRTYL FTYAPFYDTL AIATLSSMFE LDSRKVSAVV SKMISHEELA AALDQVTETV 

       790        800        810        820        830        840 
IFRKGVELSR LQSLALTLSD KASSLIETNE RTLEQKTQGS ANAFSRKDNR GGGQRGGGQR 

       850        860        870 
GGRGGARTGG NPQRQAGGTQ FTGGALGNAV RG 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CM002238 Genomic DNA. Translation: EAA33716.1.
RefSeqXP_962952.1. XM_957859.2.
UniGeneNcr.23166.

3D structure databases

ProteinModelPortalQ7SBD4.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING5141.NCU07831.1.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiEFNCRT00000007481; EFNCRP00000007471; EFNCRG00000007469.
GeneID3879100.
KEGGncr:NCU07831.

Phylogenomic databases

eggNOGNOG305883.
HOGENOMHOG000029414.
KOK03252.
OMAEEGKQTV.
OrthoDBEOG75QRCP.

Family and domain databases

Gene3D1.10.10.10. 1 hit.
HAMAPMF_03002. eIF3c.
InterProIPR027516. EIF3C.
IPR008905. EIF3C_N_dom.
IPR000717. PCI_dom.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PfamPF05470. eIF-3c_N. 1 hit.
PF01399. PCI. 1 hit.
[Graphical view]
SMARTSM00088. PINT. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameEIF3C_NEUCR
AccessionPrimary (citable) accession number: Q7SBD4
Entry history
Integrated into UniProtKB/Swiss-Prot: March 3, 2009
Last sequence update: December 15, 2003
Last modified: February 19, 2014
This is version 69 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Translation initiation factors

List of translation initiation factor entries