Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Eukaryotic translation initiation factor 3 subunit C

Gene

nip-1

Organism
Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionInitiation factor
Biological processProtein biosynthesis

Names & Taxonomyi

Protein namesi
Recommended name:
Eukaryotic translation initiation factor 3 subunit CUniRule annotation
Short name:
eIF3cUniRule annotation
Alternative name(s):
Eukaryotic translation initiation factor 3 93 kDa subunit homologUniRule annotation
Short name:
eIF3 p93UniRule annotation
Translation initiation factor eIF3, p93 subunit homologUniRule annotation
Gene namesi
Name:nip-1
ORF Names:NCU07831
OrganismiNeurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)
Taxonomic identifieri367110 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaSordariomycetesSordariomycetidaeSordarialesSordariaceaeNeurospora
Proteomesi
  • UP000001805 Componenti: Chromosome 3, Linkage Group III

Organism-specific databases

EuPathDBiFungiDB:NCU07831

Subcellular locationi

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003642871 – 872Eukaryotic translation initiation factor 3 subunit CAdd BLAST872

Interactioni

Subunit structurei

Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.UniRule annotation

GO - Molecular functioni

Structurei

3D structure databases

ProteinModelPortaliQ7SBD4
SMRiQ7SBD4
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini613 – 787PCIPROSITE-ProRule annotationAdd BLAST175

Sequence similaritiesi

Belongs to the eIF-3 subunit C family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000029414
InParanoidiQ7SBD4
KOiK03252
OMAiVVMHRSE
OrthoDBiEOG092C17F5

Family and domain databases

Gene3Di1.10.10.10, 1 hit
HAMAPiMF_03002 eIF3c, 1 hit
InterProiView protein in InterPro
IPR027516 EIF3C
IPR008905 EIF3C_N_dom
IPR000717 PCI_dom
IPR036388 WH-like_DNA-bd_sf
IPR036390 WH_DNA-bd_sf
PfamiView protein in Pfam
PF05470 eIF-3c_N, 1 hit
PF01399 PCI, 1 hit
SMARTiView protein in SMART
SM00088 PINT, 1 hit
SUPFAMiSSF46785 SSF46785, 1 hit
PROSITEiView protein in PROSITE
PS50250 PCI, 1 hit

Sequencei

Sequence statusi: Complete.

Q7SBD4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSRFFRGGDD SSTDSSSEEE EVYTSEEEEE KVQAEDESSS EEESDEEESD
60 70 80 90 100
EESSSDEEEG TKKKGASRFL QSDDESEEEE EEQSDDEATT KVKSAKDKRF
110 120 130 140 150
DELESTISQI QNGQKINDWS LIANEFDKLN RQVVKLQDGS KAPKSYIKAI
160 170 180 190 200
ADLEDFMNET LAKQKVTPKK MNATNARGLN AVKQRIRKNN KEYQTQIDAY
210 220 230 240 250
RKDADAFMES DDEVAAPKVV SKVRFEAPVV SAEQQEEDDK GFSTVDSRGK
260 270 280 290 300
VVQYTPESIL KHLRAIIESR GKKNTDRLEQ IKVMETLNKV VPITPYQKIR
310 320 330 340 350
VLQTLISARF DLGAGGAAQM PLDQWKAAER DLASLLEILE KEKDHVVVEG
360 370 380 390 400
AEEWDDDDKL PTIPEGEKYL KVPGSVVSLI ERLDDELTRS LQAIDPHTSE
410 420 430 440 450
YIDRLTDEGS LYNTIFRGLL YYEHLRKDAS LEVPQESLNR IIQRRLDHVY
460 470 480 490 500
YKPAQVVKIL EENAWKQVSA EADSEITPRS QSGDAGKLIN ILSNYLFENS
510 520 530 540 550
EGIIRARAML CQIYFLALHD EYYKSRDLML TSHLQETIAN FDIATQILYN
560 570 580 590 600
RTLVQVGLCA FRKGLVYDAQ NTLQEICGSG RQKELLAQGV MIQRYSQVTP
610 620 630 640 650
EQERLEKQRQ LPFHMHINLE LLECVYLTCS MLLEIPLLAQ TGSSPDVKKR
660 670 680 690 700
IISKTYRRML EYHERQIFTG PPENTRDHVM QASKALAAGE WKKATDFIHS
710 720 730 740 750
IKIWDLMPNT EGIKTMLAKQ IQEEGLRTYL FTYAPFYDTL AIATLSSMFE
760 770 780 790 800
LDSRKVSAVV SKMISHEELA AALDQVTETV IFRKGVELSR LQSLALTLSD
810 820 830 840 850
KASSLIETNE RTLEQKTQGS ANAFSRKDNR GGGQRGGGQR GGRGGARTGG
860 870
NPQRQAGGTQ FTGGALGNAV RG
Length:872
Mass (Da):98,399
Last modified:December 15, 2003 - v1
Checksum:i38611B9B0CC93EA1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CM002238 Genomic DNA Translation: EAA33716.1
RefSeqiXP_962952.1, XM_957859.3

Genome annotation databases

EnsemblFungiiEAA33716; EAA33716; NCU07831
GeneIDi3879100
KEGGincr:NCU07831

Similar proteinsi

Entry informationi

Entry nameiEIF3C_NEUCR
AccessioniPrimary (citable) accession number: Q7SBD4
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 3, 2009
Last sequence update: December 15, 2003
Last modified: May 23, 2018
This is version 91 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Cookie policy

We would like to use anonymized google analytics cookies to gather statistics on how uniprot.org is used in aggregate. Learn more

UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health