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Protein

Aspartate aminotransferase

Gene

NCU07941

Organism
Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate.UniRule annotation

Cofactori

pyridoxal 5'-phosphateUniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

AminotransferaseUniRule annotationImported, Transferase

Keywords - Ligandi

Pyridoxal phosphateUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Aspartate aminotransferaseUniRule annotation (EC:2.6.1.1UniRule annotation)
Gene namesi
ORF Names:NCU07941Imported
OrganismiNeurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)Imported
Taxonomic identifieri367110 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaSordariomycetesSordariomycetidaeSordarialesSordariaceaeNeurospora
Proteomesi
  • UP000001805 Componenti: Chromosome 4, Linkage Group IV

Organism-specific databases

EuPathDBiFungiDB:NCU07941.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Interactioni

Subunit structurei

Homodimer.UniRule annotation

GO - Molecular functioni

Structurei

3D structure databases

ProteinModelPortaliQ7S9X7.
SMRiQ7S9X7. Positions 72-481.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini96 – 474379Aminotran_1_2InterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000185898.
InParanoidiQ7S9X7.
KOiK14454.
OMAiRVGACTI.
OrthoDBiEOG793BHW.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
InterProiIPR004839. Aminotransferase_I/II.
IPR000796. Asp_trans.
IPR004838. NHTrfase_class1_PyrdxlP-BS.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
[Graphical view]
PANTHERiPTHR11879. PTHR11879. 1 hit.
PfamiPF00155. Aminotran_1_2. 1 hit.
[Graphical view]
PRINTSiPR00799. TRANSAMINASE.
SUPFAMiSSF53383. SSF53383. 1 hit.
PROSITEiPS00105. AA_TRANSFER_CLASS_1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q7S9X7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAPASTLLRA AAPAPHAHTS FPSHHTPTSS PNRTTITNTN PSANSTSSTP
60 70 80 90 100
LHRIQTIAKH MALPQITSFP AEVVPQAPED PLFGLARAFK ADPSPQKVDL
110 120 130 140 150
GIGAYRDENA KPWVLPVVKK ADEIIRNDPE ANHEYLPIAG LASLTSKAAE
160 170 180 190 200
LVVGASAPAI TEGRVASIQT ISGTGACHLG GLFLSRFYNP YGDASKKPTV
210 220 230 240 250
YLSNPTWANH NQIFSNVGLP IAQYPYFDQK TKGLDIDGMK KALSDAPERS
260 270 280 290 300
IILLHACAHN PTGVDPTLAQ WREIAEIMAA KGHFPFFDTA YQGFASGDLD
310 320 330 340 350
RDASAIRLFV ELGFELVVAQ SFAKNFGLYG QRAGCFHFIS APSPDAASIT
360 370 380 390 400
TRVASQLTLL QRSEISNPPI YGAKVASIVL NDPALFAEWK ENLRTMSGRI
410 420 430 440 450
IDMRKALRAK LEELGTPGPW NHITDQIGMF SFTGLNEKQV AKLREEFHIY
460 470 480
MTKNGRISMA GLNKKNVDYV ARAVDKVVRE VQ
Length:482
Mass (Da):52,390
Last modified:December 15, 2003 - v1
Checksum:i0B967FCD86559077
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CM002239 Genomic DNA. Translation: EAA33221.1.
RefSeqiXP_962457.1. XM_957364.2.

Genome annotation databases

EnsemblFungiiEFNCRT00000008162; EFNCRP00000008151; EFNCRG00000008148.
GeneIDi3878589.
KEGGincr:NCU07941.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CM002239 Genomic DNA. Translation: EAA33221.1.
RefSeqiXP_962457.1. XM_957364.2.

3D structure databases

ProteinModelPortaliQ7S9X7.
SMRiQ7S9X7. Positions 72-481.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiEFNCRT00000008162; EFNCRP00000008151; EFNCRG00000008148.
GeneIDi3878589.
KEGGincr:NCU07941.

Organism-specific databases

EuPathDBiFungiDB:NCU07941.

Phylogenomic databases

HOGENOMiHOG000185898.
InParanoidiQ7S9X7.
KOiK14454.
OMAiRVGACTI.
OrthoDBiEOG793BHW.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
InterProiIPR004839. Aminotransferase_I/II.
IPR000796. Asp_trans.
IPR004838. NHTrfase_class1_PyrdxlP-BS.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
[Graphical view]
PANTHERiPTHR11879. PTHR11879. 1 hit.
PfamiPF00155. Aminotran_1_2. 1 hit.
[Graphical view]
PRINTSiPR00799. TRANSAMINASE.
SUPFAMiSSF53383. SSF53383. 1 hit.
PROSITEiPS00105. AA_TRANSFER_CLASS_1. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "The genome sequence of the filamentous fungus Neurospora crassa."
    Galagan J.E., Calvo S.E., Borkovich K.A., Selker E.U., Read N.D., Jaffe D., FitzHugh W., Ma L.J., Smirnov S., Purcell S., Rehman B., Elkins T., Engels R., Wang S., Nielsen C.B., Butler J., Endrizzi M., Qui D.
    , Ianakiev P., Bell-Pedersen D., Nelson M.A., Werner-Washburne M., Selitrennikoff C.P., Kinsey J.A., Braun E.L., Zelter A., Schulte U., Kothe G.O., Jedd G., Mewes W., Staben C., Marcotte E., Greenberg D., Roy A., Foley K., Naylor J., Stange-Thomann N., Barrett R., Gnerre S., Kamal M., Kamvysselis M., Mauceli E., Bielke C., Rudd S., Frishman D., Krystofova S., Rasmussen C., Metzenberg R.L., Perkins D.D., Kroken S., Cogoni C., Macino G., Catcheside D., Li W., Pratt R.J., Osmani S.A., DeSouza C.P., Glass L., Orbach M.J., Berglund J.A., Voelker R., Yarden O., Plamann M., Seiler S., Dunlap J., Radford A., Aramayo R., Natvig D.O., Alex L.A., Mannhaupt G., Ebbole D.J., Freitag M., Paulsen I., Sachs M.S., Lander E.S., Nusbaum C., Birren B.
    Nature 422:859-868(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987Imported.

Entry informationi

Entry nameiQ7S9X7_NEUCR
AccessioniPrimary (citable) accession number: Q7S9X7
Entry historyi
Integrated into UniProtKB/TrEMBL: December 15, 2003
Last sequence update: December 15, 2003
Last modified: June 8, 2016
This is version 88 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Miscellaneous

In eukaryotes there are cytoplasmic, mitochondrial and chloroplastic isozymes.UniRule annotation

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.