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Protein
Submitted name:

Hexokinase-1

Gene

NCU04728

Organism
Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. kinase activity Source: UniProtKB-KW
  3. phosphotransferase activity, alcohol group as acceptor Source: InterPro

GO - Biological processi

  1. glycolytic process Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

KinaseSAAS annotationImported, Transferase

Keywords - Biological processi

GlycolysisSAAS annotation

Keywords - Ligandi

ATP-bindingSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
Hexokinase-1Imported
Gene namesi
ORF Names:NCU04728Imported
OrganismiNeurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)Imported
Taxonomic identifieri367110 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaSordariomycetesSordariomycetidaeSordarialesSordariaceaeNeurospora
ProteomesiUP000001805: Chromosome 5, Linkage Group VI

Interactioni

Protein-protein interaction databases

STRINGi5141.NCU04728.1.

Structurei

3D structure databases

ProteinModelPortaliQ7S6H6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the hexokinase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG5026.
HOGENOMiHOG000179996.
InParanoidiQ7S6H6.
KOiK00844.
OMAiILPLTRW.
OrthoDBiEOG79SF68.

Family and domain databases

InterProiIPR001312. Hexokinase.
IPR022673. Hexokinase_C.
IPR022672. Hexokinase_N.
[Graphical view]
PANTHERiPTHR19443. PTHR19443. 1 hit.
PfamiPF00349. Hexokinase_1. 1 hit.
PF03727. Hexokinase_2. 1 hit.
[Graphical view]
PRINTSiPR00475. HEXOKINASE.

Sequencei

Sequence statusi: Complete.

Q7S6H6-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MASLKLLIIN ALKSLSRGRS FLQALLALWI SPKSNPNKLK KIKVFRRTRE
60 70 80 90 100
EFLKEAKKLL LGPIGSNHFI KNSGPTPDDP LLLLSKKLEA QFRQGLQTSP
110 120 130 140 150
ACMLPSYNHQ LPGGHESGQY LAVDIGGSTL RVGVVDLKGR QTTDDDDSTI
160 170 180 190 200
VHMDSYKIDR NVRLLRGAFF FKWMARKVET SLKKAIDAGH ISKAEYELGN
210 220 230 240 250
PMPMGLAWSF PLEQTSPNGG NICPMGKSFL ACDGLMGQDL GATCNKILQE
260 270 280 290 300
LRVNVEVVSI VNDSNATLLS SAYSSPSARF GLILGTGVNI AAHLPVNLIG
310 320 330 340 350
KSKFGERPDS WYEQASHVMV NTELGMFGRD ILPLTRWDKI LKAGHERPDF
360 370 380 390 400
QPLEHLVSGY YLGEVFRIAL LEAIKTTGLL GGKIPPLLLD AYSMDTGTMS
410 420 430 440 450
LIINGRDARG KAEAVFSQLY HLPAGYPSTE DMRFMQQLAG YIAQRSASIV
460 470 480 490 500
AASVFALWEL KNEAEQNVLN NLEPESPFSE ETALELMMEQ TTVGYTGSVL
510 520 530 540 550
ECFPGYKETL QRYLDQLMMS SGHDLKGRRI DLVPAKESSL LGAAVSLAGV
560
VEEERMGLNE KKGIA
Length:565
Mass (Da):62,106
Last modified:December 15, 2003 - v1
Checksum:iF2B95A696312E389
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CM002241 Genomic DNA. Translation: EAA31127.1.
RefSeqiXP_960363.1. XM_955270.1.
UniGeneiNcr.20964.

Genome annotation databases

EnsemblFungiiEFNCRT00000004530; EFNCRP00000004530; EFNCRG00000004524.
GeneIDi3876501.
KEGGincr:NCU04728.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CM002241 Genomic DNA. Translation: EAA31127.1.
RefSeqiXP_960363.1. XM_955270.1.
UniGeneiNcr.20964.

3D structure databases

ProteinModelPortaliQ7S6H6.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi5141.NCU04728.1.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiEFNCRT00000004530; EFNCRP00000004530; EFNCRG00000004524.
GeneIDi3876501.
KEGGincr:NCU04728.

Phylogenomic databases

eggNOGiCOG5026.
HOGENOMiHOG000179996.
InParanoidiQ7S6H6.
KOiK00844.
OMAiILPLTRW.
OrthoDBiEOG79SF68.

Family and domain databases

InterProiIPR001312. Hexokinase.
IPR022673. Hexokinase_C.
IPR022672. Hexokinase_N.
[Graphical view]
PANTHERiPTHR19443. PTHR19443. 1 hit.
PfamiPF00349. Hexokinase_1. 1 hit.
PF03727. Hexokinase_2. 1 hit.
[Graphical view]
PRINTSiPR00475. HEXOKINASE.
ProtoNetiSearch...

Publicationsi

  1. "The genome sequence of the filamentous fungus Neurospora crassa."
    Galagan J.E., Calvo S.E., Borkovich K.A., Selker E.U., Read N.D., Jaffe D.B., FitzHugh W., Ma L.-J., Smirnov S., Purcell S., Rehman B., Elkins T., Engels R., Wang S., Nielsen C.B., Butler J., Endrizzi M., Qui D.
    , Ianakiev P., Bell-Pedersen D., Nelson M.A., Werner-Washburne M., Selitrennikoff C.P., Kinsey J.A., Braun E.L., Zelter A., Schulte U., Kothe G.O., Jedd G., Mewes H.-W., Staben C., Marcotte E., Greenberg D., Roy A., Foley K., Naylor J., Stange-Thomann N., Barrett R., Gnerre S., Kamal M., Kamvysselis M., Mauceli E.W., Bielke C., Rudd S., Frishman D., Krystofova S., Rasmussen C., Metzenberg R.L., Perkins D.D., Kroken S., Cogoni C., Macino G., Catcheside D.E.A., Li W., Pratt R.J., Osmani S.A., DeSouza C.P.C., Glass N.L., Orbach M.J., Berglund J.A., Voelker R., Yarden O., Plamann M., Seiler S., Dunlap J.C., Radford A., Aramayo R., Natvig D.O., Alex L.A., Mannhaupt G., Ebbole D.J., Freitag M., Paulsen I., Sachs M.S., Lander E.S., Nusbaum C., Birren B.W.
    Nature 422:859-868(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987Imported.

Entry informationi

Entry nameiQ7S6H6_NEUCR
AccessioniPrimary (citable) accession number: Q7S6H6
Entry historyi
Integrated into UniProtKB/TrEMBL: December 15, 2003
Last sequence update: December 15, 2003
Last modified: February 4, 2015
This is version 71 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.