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Q7RYJ3

- Q7RYJ3_NEUCR

UniProt

Q7RYJ3 - Q7RYJ3_NEUCR

Protein

DNA ligase

Gene

NCU06481

Organism
Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 78 (01 Oct 2014)
      Sequence version 1 (15 Dec 2003)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    ATP + (deoxyribonucleotide)(n) + (deoxyribonucleotide)(m) = AMP + diphosphate + (deoxyribonucleotide)(n+m).UniRule annotation

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. DNA binding Source: InterPro
    3. DNA ligase (ATP) activity Source: RefGenome

    GO - Biological processi

    1. DNA ligation Source: RefGenome
    2. DNA ligation involved in DNA repair Source: InterPro
    3. DNA recombination Source: UniProtKB-KW
    4. lagging strand elongation Source: RefGenome
    5. nucleotide-excision repair Source: RefGenome

    Keywords - Molecular functioni

    LigaseUniRule annotationImported

    Keywords - Biological processi

    DNA damage, DNA recombinationUniRule annotation, DNA repairUniRule annotation, DNA replicationUniRule annotation

    Keywords - Ligandi

    ATP-bindingUniRule annotation, Nucleotide-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    DNA ligaseUniRule annotation (EC:6.5.1.1UniRule annotation)
    Gene namesi
    ORF Names:NCU06481Imported
    OrganismiNeurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)Imported
    Taxonomic identifieri367110 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaSordariomycetesSordariomycetidaeSordarialesSordariaceaeNeurospora
    ProteomesiUP000001805: Chromosome 3, Linkage Group III

    Subcellular locationi

    GO - Cellular componenti

    1. chromosome Source: RefGenome
    2. mitochondrion Source: RefGenome
    3. nucleus Source: RefGenome

    Interactioni

    Protein-protein interaction databases

    STRINGi5141.NCU06481.1.

    Structurei

    3D structure databases

    ProteinModelPortaliQ7RYJ3.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Phylogenomic databases

    eggNOGiCOG1793.
    HOGENOMiHOG000036006.
    KOiK10747.
    OMAiMVKMLEG.
    OrthoDBiEOG7TXKRG.

    Family and domain databases

    Gene3Di1.10.3260.10. 1 hit.
    2.40.50.140. 1 hit.
    InterProiIPR000977. DNA_ligase_ATP-dep.
    IPR012309. DNA_ligase_ATP-dep_C.
    IPR012310. DNA_ligase_ATP-dep_cent.
    IPR016059. DNA_ligase_ATP-dep_CS.
    IPR012308. DNA_ligase_ATP-dep_N.
    IPR012340. NA-bd_OB-fold.
    [Graphical view]
    PfamiPF04679. DNA_ligase_A_C. 1 hit.
    PF01068. DNA_ligase_A_M. 1 hit.
    PF04675. DNA_ligase_A_N. 1 hit.
    [Graphical view]
    SUPFAMiSSF117018. SSF117018. 1 hit.
    SSF50249. SSF50249. 1 hit.
    TIGRFAMsiTIGR00574. dnl1. 1 hit.
    PROSITEiPS00697. DNA_LIGASE_A1. 1 hit.
    PS00333. DNA_LIGASE_A2. 1 hit.
    PS50160. DNA_LIGASE_A3. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q7RYJ3-1 [UniParc]FASTAAdd to Basket

    « Hide

    MPPKQQQTLG KFFGKADAPA GGKQQTKLSF GTKATSTTSS KTKEEPKKDE    50
    IAGEDGGHEE VEKKVEEMKI KDKSPAKTGR GRGRPAKGKE VAKEVAKEKS 100
    SAEEDEDVME VVEEVKEETG NKKKRSRSPT TKSPKSKKAK TEEDSEDVAP 150
    ASKRSRRSRK VVEDDEDETM EDVPASSAPV KEEKSKKAAS PKPALKKKSS 200
    SPAPVEKAND AEASSASASE IEAEEEDEDE KTEAVAKEAR KVIQTTLATK 250
    VKDPYPDWKA GEPVPYAALC TTFSLIEQTR KRLLIMEYCS LFLRQVLRLT 300
    PDDLLPTVLL MINKLAPDYA GIELGIGESL IMKAIGETTG RSIAVVKNDQ 350
    KEIGDLGLVA VKSRSKQPTM FKPKPLTIRG VHKGLMDIAT TMTGTGAQQK 400
    KVDGIKKLLS AADANSTGKV DITKDKGGPS EAKFIVRFLE GKLRLGLAEK 450
    SVIVSLAQAM IAHEFAQKGK IPSESDFSKA ESILKTVYSE LPSYDVIIPA 500
    MLQHGIMNLR EHCKLRPGVP LKPMLANPTK AITEVLDRFE GQTFTCEYKY 550
    DGERAQIHYV AKDVPKSEGD LSQVASKDTG KGVAAIFSRN SEDLSQKYPD 600
    VLAKLPTWVK EGTKSFVLDC ESVAWDTVDK KVLPFQQLMT RKKKDVKLED 650
    VKVKVCVFAF DLLYLNGQAV VEKSLRERRE LLREAFKPVE GEFAFATSMD 700
    GQELDEIQSF LDESVKAGCE GLMVKMLDGA ESGYEPSKRS RNWLKIKKDY 750
    LAGIGDSLDL VVLGAYHGKG KRTSVFGAFL LACYNPSTDT YETVCNIGTG 800
    FSDEVLQELH SSLSPIIIDR PKPFYAHSSG GQHQPDVWFE PKYVWEVKTA 850
    DLTLSPRYKA GMKEGVDPSG EKGISLRFPR FIKVRDDKKP DEATTSRMVA 900
    EMYRKQESVG KNKGPAVDDN FEY 923
    Length:923
    Mass (Da):101,799
    Last modified:December 15, 2003 - v1
    Checksum:iCE1A00706465A807
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CM002238 Genomic DNA. Translation: EAA27885.1.
    RefSeqiXP_957121.1. XM_952028.1.
    UniGeneiNcr.25681.

    Genome annotation databases

    EnsemblFungiiEFNCRT00000006215; EFNCRP00000006207; EFNCRG00000006204.
    GeneIDi3873294.
    KEGGincr:NCU06481.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CM002238 Genomic DNA. Translation: EAA27885.1 .
    RefSeqi XP_957121.1. XM_952028.1.
    UniGenei Ncr.25681.

    3D structure databases

    ProteinModelPortali Q7RYJ3.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 5141.NCU06481.1.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblFungii EFNCRT00000006215 ; EFNCRP00000006207 ; EFNCRG00000006204 .
    GeneIDi 3873294.
    KEGGi ncr:NCU06481.

    Phylogenomic databases

    eggNOGi COG1793.
    HOGENOMi HOG000036006.
    KOi K10747.
    OMAi MVKMLEG.
    OrthoDBi EOG7TXKRG.

    Family and domain databases

    Gene3Di 1.10.3260.10. 1 hit.
    2.40.50.140. 1 hit.
    InterProi IPR000977. DNA_ligase_ATP-dep.
    IPR012309. DNA_ligase_ATP-dep_C.
    IPR012310. DNA_ligase_ATP-dep_cent.
    IPR016059. DNA_ligase_ATP-dep_CS.
    IPR012308. DNA_ligase_ATP-dep_N.
    IPR012340. NA-bd_OB-fold.
    [Graphical view ]
    Pfami PF04679. DNA_ligase_A_C. 1 hit.
    PF01068. DNA_ligase_A_M. 1 hit.
    PF04675. DNA_ligase_A_N. 1 hit.
    [Graphical view ]
    SUPFAMi SSF117018. SSF117018. 1 hit.
    SSF50249. SSF50249. 1 hit.
    TIGRFAMsi TIGR00574. dnl1. 1 hit.
    PROSITEi PS00697. DNA_LIGASE_A1. 1 hit.
    PS00333. DNA_LIGASE_A2. 1 hit.
    PS50160. DNA_LIGASE_A3. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The genome sequence of the filamentous fungus Neurospora crassa."
      Galagan J.E., Calvo S.E., Borkovich K.A., Selker E.U., Read N.D., Jaffe D.B., FitzHugh W., Ma L.-J., Smirnov S., Purcell S., Rehman B., Elkins T., Engels R., Wang S., Nielsen C.B., Butler J., Endrizzi M., Qui D.
      , Ianakiev P., Bell-Pedersen D., Nelson M.A., Werner-Washburne M., Selitrennikoff C.P., Kinsey J.A., Braun E.L., Zelter A., Schulte U., Kothe G.O., Jedd G., Mewes H.-W., Staben C., Marcotte E., Greenberg D., Roy A., Foley K., Naylor J., Stange-Thomann N., Barrett R., Gnerre S., Kamal M., Kamvysselis M., Mauceli E.W., Bielke C., Rudd S., Frishman D., Krystofova S., Rasmussen C., Metzenberg R.L., Perkins D.D., Kroken S., Cogoni C., Macino G., Catcheside D.E.A., Li W., Pratt R.J., Osmani S.A., DeSouza C.P.C., Glass N.L., Orbach M.J., Berglund J.A., Voelker R., Yarden O., Plamann M., Seiler S., Dunlap J.C., Radford A., Aramayo R., Natvig D.O., Alex L.A., Mannhaupt G., Ebbole D.J., Freitag M., Paulsen I., Sachs M.S., Lander E.S., Nusbaum C., Birren B.W.
      Nature 422:859-868(2003) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987Imported.

    Entry informationi

    Entry nameiQ7RYJ3_NEUCR
    AccessioniPrimary (citable) accession number: Q7RYJ3
    Entry historyi
    Integrated into UniProtKB/TrEMBL: December 15, 2003
    Last sequence update: December 15, 2003
    Last modified: October 1, 2014
    This is version 78 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Caution

    The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3