##gff-version 3
Q7RTT9	UniProtKB	Chain	1	530	.	.	.	ID=PRO_0000326251;Note=Equilibrative nucleoside transporter 4	
Q7RTT9	UniProtKB	Topological domain	1	68	.	.	.	Note=Extracellular;Ontology_term=ECO:0000255;evidence=ECO:0000255	
Q7RTT9	UniProtKB	Transmembrane	69	89	.	.	.	Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255	
Q7RTT9	UniProtKB	Topological domain	90	101	.	.	.	Note=Cytoplasmic;Ontology_term=ECO:0000255;evidence=ECO:0000255	
Q7RTT9	UniProtKB	Transmembrane	102	122	.	.	.	Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255	
Q7RTT9	UniProtKB	Topological domain	123	139	.	.	.	Note=Extracellular;Ontology_term=ECO:0000255;evidence=ECO:0000255	
Q7RTT9	UniProtKB	Transmembrane	140	160	.	.	.	Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255	
Q7RTT9	UniProtKB	Topological domain	161	166	.	.	.	Note=Cytoplasmic;Ontology_term=ECO:0000255;evidence=ECO:0000255	
Q7RTT9	UniProtKB	Transmembrane	167	187	.	.	.	Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255	
Q7RTT9	UniProtKB	Topological domain	188	231	.	.	.	Note=Extracellular;Ontology_term=ECO:0000255;evidence=ECO:0000255	
Q7RTT9	UniProtKB	Transmembrane	232	252	.	.	.	Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255	
Q7RTT9	UniProtKB	Topological domain	253	351	.	.	.	Note=Cytoplasmic;Ontology_term=ECO:0000255;evidence=ECO:0000255	
Q7RTT9	UniProtKB	Transmembrane	352	372	.	.	.	Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255	
Q7RTT9	UniProtKB	Topological domain	373	381	.	.	.	Note=Extracellular;Ontology_term=ECO:0000255;evidence=ECO:0000255	
Q7RTT9	UniProtKB	Transmembrane	382	402	.	.	.	Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255	
Q7RTT9	UniProtKB	Topological domain	403	416	.	.	.	Note=Cytoplasmic;Ontology_term=ECO:0000255;evidence=ECO:0000255	
Q7RTT9	UniProtKB	Transmembrane	417	437	.	.	.	Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255	
Q7RTT9	UniProtKB	Topological domain	438	450	.	.	.	Note=Extracellular;Ontology_term=ECO:0000255;evidence=ECO:0000255	
Q7RTT9	UniProtKB	Transmembrane	451	471	.	.	.	Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255	
Q7RTT9	UniProtKB	Topological domain	472	486	.	.	.	Note=Cytoplasmic;Ontology_term=ECO:0000255;evidence=ECO:0000255	
Q7RTT9	UniProtKB	Transmembrane	487	509	.	.	.	Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255	
Q7RTT9	UniProtKB	Topological domain	510	530	.	.	.	Note=Extracellular;Ontology_term=ECO:0000255;evidence=ECO:0000255	
Q7RTT9	UniProtKB	Region	1	21	.	.	.	Note=Disordered;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
Q7RTT9	UniProtKB	Site	206	206	.	.	.	Note=Essential for cation selectivity;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:16873718;Dbxref=PMID:16873718	
Q7RTT9	UniProtKB	Glycosylation	523	523	.	.	.	Note=N-linked (GlcNAc...) asparagine;Ontology_term=ECO:0000255;evidence=ECO:0000255	
Q7RTT9	UniProtKB	Alternative sequence	139	182	.	.	.	ID=VSP_032647;Note=In isoform 2. GYLLALGPLLFISICDVWLQLFSRDQAYAINLAAVGTVAFGCTV->ASATCGCSSSLGTRPTPSTWPLWAPWPSAA;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:15489334;Dbxref=PMID:15489334	
Q7RTT9	UniProtKB	Natural variant	79	79	.	.	.	ID=VAR_040044;Note=V->E;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:15489334;Dbxref=dbSNP:rs17854505,PMID:15489334	
Q7RTT9	UniProtKB	Natural variant	124	124	.	.	.	ID=VAR_040045;Note=N->K;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:15489334;Dbxref=dbSNP:rs17855675,PMID:15489334	
Q7RTT9	UniProtKB	Natural variant	429	429	.	.	.	ID=VAR_040046;Note=P->T;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:15489334;Dbxref=dbSNP:rs17857336,PMID:15489334	
Q7RTT9	UniProtKB	Mutagenesis	91	91	.	.	.	Note=No significant change in dopamine%2C serotonin and MPP(+) uptake. D->A;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:17121826;Dbxref=PMID:17121826	
Q7RTT9	UniProtKB	Mutagenesis	107	107	.	.	.	Note=Loss of dopamine%2C serotonin and MPP(+) uptake. D->A;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:17121826;Dbxref=PMID:17121826	
Q7RTT9	UniProtKB	Mutagenesis	128	128	.	.	.	Note=No significant change in dopamine%2C serotonin and MPP(+) uptake. E->A;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:17121826;Dbxref=PMID:17121826	
Q7RTT9	UniProtKB	Mutagenesis	154	154	.	.	.	Note=Loss of dopamine%2C serotonin and MPP(+) uptake%3B increased uridine uptake. D->A;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:17121826;Dbxref=PMID:17121826	
Q7RTT9	UniProtKB	Mutagenesis	163	163	.	.	.	Note=Loss of dopamine%2C serotonin and MPP(+) uptake. D->A;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:17121826;Dbxref=PMID:17121826	
Q7RTT9	UniProtKB	Mutagenesis	206	206	.	.	.	Note=Loss of dopamine%2C serotonin and MPP(+) uptake%3B gain of uridine transport activity. E->A;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:17121826;Dbxref=PMID:17121826	
Q7RTT9	UniProtKB	Mutagenesis	206	206	.	.	.	Note=No change in dopamine%2C serotonin and MPP(+) uptake%3B no uridine uptake activity. E->D;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:17121826;Dbxref=PMID:17121826	
Q7RTT9	UniProtKB	Mutagenesis	206	206	.	.	.	Note=Loss of dopamine%2C serotonin%2C adenosine and MPP(+) uptake%3B gain of uridine transport activity. E->Q;Ontology_term=ECO:0000269,ECO:0000269;evidence=ECO:0000269|PubMed:16873718,ECO:0000269|PubMed:17121826;Dbxref=PMID:16873718,PMID:17121826	
Q7RTT9	UniProtKB	Mutagenesis	206	206	.	.	.	Note=Loss of dopamine%2C serotonin and MPP(+) uptake%3B no uridine uptake activity. E->R;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:17121826;Dbxref=PMID:17121826	
Q7RTT9	UniProtKB	Mutagenesis	220	220	.	.	.	Note=Reduced dopamine%2C serotonin and MPP(+) uptake. T->A;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:17121826;Dbxref=PMID:17121826	
Q7RTT9	UniProtKB	Mutagenesis	220	220	.	.	.	Note=Loss of dopamine%2C serotonin and MPP(+) uptake. T->I;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:17121826;Dbxref=PMID:17121826	
Q7RTT9	UniProtKB	Mutagenesis	220	220	.	.	.	Note=Reduced dopamine%2C serotonin and MPP(+) uptake. T->S;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:17121826;Dbxref=PMID:17121826	
Q7RTT9	UniProtKB	Mutagenesis	227	227	.	.	.	Note=Functional with slight increased dopamine%2C serotonin and MPP(+) uptake. E->A;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:17121826;Dbxref=PMID:17121826	
Q7RTT9	UniProtKB	Mutagenesis	242	242	.	.	.	Note=Reduced dopamine%2C serotonin and MPP(+) uptake. E->A;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:17121826;Dbxref=PMID:17121826	
Q7RTT9	UniProtKB	Mutagenesis	336	336	.	.	.	Note=Loss of dopamine%2C serotonin and MPP(+) uptake. W->A;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:17121826;Dbxref=PMID:17121826	
Q7RTT9	UniProtKB	Mutagenesis	375	375	.	.	.	Note=Functional with increased dopamine%2C serotonin and MPP(+) uptake. E->A;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:17121826;Dbxref=PMID:17121826	
Q7RTT9	UniProtKB	Mutagenesis	375	375	.	.	.	Note=No change in adenosine uptake. E->Q;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:16873718;Dbxref=PMID:16873718	
Q7RTT9	UniProtKB	Sequence conflict	25	25	.	.	.	Note=S->C;Ontology_term=ECO:0000305;evidence=ECO:0000305	
Q7RTT9	UniProtKB	Sequence conflict	41	41	.	.	.	Note=Q->R;Ontology_term=ECO:0000305;evidence=ECO:0000305	
Q7RTT9	UniProtKB	Sequence conflict	196	196	.	.	.	Note=K->R;Ontology_term=ECO:0000305;evidence=ECO:0000305	
Q7RTT9	UniProtKB	Sequence conflict	261	261	.	.	.	Note=Y->H;Ontology_term=ECO:0000305;evidence=ECO:0000305	
Q7RTT9	UniProtKB	Sequence conflict	301	301	.	.	.	Note=L->P;Ontology_term=ECO:0000305;evidence=ECO:0000305