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Protein
Submitted name:

Kinesin light chain 1E

Gene

KNS2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Kinesin light chain 1EImported
Gene namesi
Name:KNS2Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA162393424.

PTM / Processingi

Proteomic databases

PaxDbiQ7RTQ2.
PeptideAtlasiQ7RTQ2.
PRIDEiQ7RTQ2.

Expressioni

Gene expression databases

GenevisibleiQ7RTQ2. HS.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000414982.

Structurei

3D structure databases

ProteinModelPortaliQ7RTQ2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini213 – 414202TPR_REGIONInterPro annotationAdd
BLAST
Domaini464 – 49734TPR_REGIONInterPro annotationAdd
BLAST

Coiled coil

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Coiled coili89 – 15163Sequence analysisAdd
BLAST

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG1840. Eukaryota.
COG0457. LUCA.
HOVERGENiHBG006217.
KOiK10407.

Family and domain databases

Gene3Di1.25.40.10. 1 hit.
InterProiIPR002151. Kinesin_light.
IPR015792. Kinesin_light_repeat.
IPR013026. TPR-contain_dom.
IPR011990. TPR-like_helical_dom.
IPR019734. TPR_repeat.
[Graphical view]
PfamiPF13374. TPR_10. 2 hits.
[Graphical view]
PRINTSiPR00381. KINESINLIGHT.
SMARTiSM00028. TPR. 5 hits.
[Graphical view]
SUPFAMiSSF48452. SSF48452. 3 hits.
PROSITEiPS01160. KINESIN_LIGHT. 4 hits.
PS50005. TPR. 6 hits.
PS50293. TPR_REGION. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q7RTQ2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MYDTMSTMVY IKEDKLEKLT QDEIISKTKQ VIQGLEALKN EHNSILQSLL
60 70 80 90 100
ETLKCLKKDD ESNLVEEKSN MIRKSLEMLE LGLSEAQVMM ALSNHLNAVE
110 120 130 140 150
SEKQKLRAQV RRLCQENQWL RDELANTQQK LQKSEQSVAQ LEEEKKHLEF
160 170 180 190 200
MNQLKKYDDD ISPSEDKDTD STKEPLDDLF PNDEDDPGQG IQQQHSSAAA
210 220 230 240 250
AAQQGGYEIP ARLRTLHNLV IQYASQGRYE VAVPLCKQAL EDLEKTSGHD
260 270 280 290 300
HPDVATMLNI LALVYRDQNK YKDAANLLND ALAIREKTLG KDHPAVAATL
310 320 330 340 350
NNLAVLYGKR GKYKEAEPLC KRALEIREKV LGKDHPDVAK QLNNLALLCQ
360 370 380 390 400
NQGKYEEVEY YYQRALEIYQ TKLGPDDPNV AKTKNNLASC YLKQGKFKQA
410 420 430 440 450
ETLYKEILTR AHEREFGSVD DENKPIWMHA EEREECKGKQ KDGTSFGEYG
460 470 480 490 500
GWYKACKVDS PTVTTTLKNL GALYRRQGKF EAAETLEEAA MRSRKQGLDN
510 520 530 540 550
VHKQRVAEVL NDPENMEKRR SRESLNVDVV KYESGPDGGE EDGTGSLKRS
560 570 580 590 600
GSFSKLRASI RRSSEKLVRK LKGGSSRESE PKNPGASLAE PLFVENDSSS

SGLEDATAN
Length:609
Mass (Da):68,762
Last modified:December 15, 2003 - v1
Checksum:iCC42D0ADB681B8C7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BK001164 mRNA. Translation: DAA01290.1.
RefSeqiNP_001123579.1. NM_001130107.1.
UniGeneiHs.20107.
Hs.657678.

Genome annotation databases

GeneIDi3831.
KEGGihsa:3831.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BK001164 mRNA. Translation: DAA01290.1.
RefSeqiNP_001123579.1. NM_001130107.1.
UniGeneiHs.20107.
Hs.657678.

3D structure databases

ProteinModelPortaliQ7RTQ2.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000414982.

Proteomic databases

PaxDbiQ7RTQ2.
PeptideAtlasiQ7RTQ2.
PRIDEiQ7RTQ2.

Protocols and materials databases

DNASUi3831.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi3831.
KEGGihsa:3831.

Organism-specific databases

CTDi3831.
PharmGKBiPA162393424.

Phylogenomic databases

eggNOGiKOG1840. Eukaryota.
COG0457. LUCA.
HOVERGENiHBG006217.
KOiK10407.

Miscellaneous databases

ChiTaRSiKLC1. human.
GenomeRNAii3831.

Gene expression databases

GenevisibleiQ7RTQ2. HS.

Family and domain databases

Gene3Di1.25.40.10. 1 hit.
InterProiIPR002151. Kinesin_light.
IPR015792. Kinesin_light_repeat.
IPR013026. TPR-contain_dom.
IPR011990. TPR-like_helical_dom.
IPR019734. TPR_repeat.
[Graphical view]
PfamiPF13374. TPR_10. 2 hits.
[Graphical view]
PRINTSiPR00381. KINESINLIGHT.
SMARTiSM00028. TPR. 5 hits.
[Graphical view]
SUPFAMiSSF48452. SSF48452. 3 hits.
PROSITEiPS01160. KINESIN_LIGHT. 4 hits.
PS50005. TPR. 6 hits.
PS50293. TPR_REGION. 2 hits.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Alternatively spliced products of the human kinesin light chain 1 (KNS2) gene."
    McCart A.E., Mahony D., Rothnagel J.A.
    Traffic 4:576-580(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiQ7RTQ2_HUMAN
AccessioniPrimary (citable) accession number: Q7RTQ2
Entry historyi
Integrated into UniProtKB/TrEMBL: December 15, 2003
Last sequence update: December 15, 2003
Last modified: July 6, 2016
This is version 90 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Miscellaneous

The sequence shown here is derived from an EMBL/GenBank/DDBJ third party annotation (TPA) entry.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.