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Q7RT90 (OAT_PLAYO) Reviewed, UniProtKB/Swiss-Prot

Last modified December 14, 2011. Version 53. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Ornithine aminotransferase

EC=2.6.1.13
Alternative name(s):
Ornithine--oxo-acid aminotransferase
Gene names
Name:OAT
ORF Names:PY00104
OrganismPlasmodium yoelii yoelii
Taxonomic identifier73239 [NCBI]
Taxonomic lineageEukaryotaAlveolataApicomplexaAconoidasidaHaemosporidaPlasmodiumPlasmodium (Vinckeia)

Protein attributes

Sequence length414 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Catalytic activity

L-ornithine + a 2-oxo acid = L-glutamate 5-semialdehyde + an L-amino acid.

Cofactor

Pyridoxal phosphate By similarity.

Pathway

Amino-acid biosynthesis; L-proline biosynthesis; L-glutamate 5-semialdehyde from L-ornithine: step 1/1.

Subunit structure

Homotetramer By similarity.

Subcellular location

Cytoplasm Probable.

Sequence similarities

Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

Ontologies

Keywords
   Cellular componentCytoplasm
   LigandPyridoxal phosphate
   Molecular functionAminotransferase
Transferase
   Technical term3D-structure
Complete proteome
Reference proteome
Gene Ontology (GO)
   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionornithine-oxo-acid transaminase activity

Inferred from electronic annotation. Source: EC

pyridoxal phosphate binding

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 414414Ornithine aminotransferase
PRO_0000233396

Amino acid modifications

Modified residue2621N6-(pyridoxal phosphate)lysine By similarity

Secondary structure

................................................................. 414
Helix Strand Turn

Details...

Sequences

Sequence LengthMass (Da)Tools
Q7RT90 [UniParc].

Last modified December 15, 2003. Version 1.
Checksum: 65800F4730BD8B84

FASTA41446,267
        10         20         30         40         50         60 
MEFVKDLKTP EDYINNELKY GAHNYDPIPV VLKRAKGVFV YDVNDKRYYD FLSAYSSVNQ 

        70         80         90        100        110        120 
GHCHPNILNA MINQAKNLTI CSRAFFSVPL GICERYLTNL LGYDKVLMMN TGAEANETAY 

       130        140        150        160        170        180 
KLCRKWGYEV KKIPENMAKI VVCKNNFSGR TLGCISASTT KKCTSNFGPF APQFSKVPYD 

       190        200        210        220        230        240 
DLEALEEELK DPNVCAFIVE PIQGEAGVIV PSDNYLQGVY DICKKYNVLF VADEVQTGLG 

       250        260        270        280        290        300 
RTGKLLCVHH YNVKPDVILL GKALSGGHYP ISAVLANDDI MLVIKPGEHG STYGGNPLAA 

       310        320        330        340        350        360 
SICVEALNVL INEKLCENAE KLGGPFLENL KRELKDSKIV RDVRGKGLLC AIEFKNELVN 

       370        380        390        400        410 
VLDICLKLKE NGLITRDVHD KTIRLTPPLC ITKEQLDECT EIIVKTVKFF DERF 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AABL01000033 Genomic DNA. Translation: EAA20544.1.
RefSeqXP_728979.1. XM_723886.1.

3D structure databases

PDBe
RCSB PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
1Z7DX-ray2.10A/B/C/D/E/F1-414[»]
ProteinModelPortalQ7RT90.
SMRQ7RT90. Positions 8-411.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ7RT90.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID3801528.
KEGGpyo:PY00104.

Organism-specific databases

EuPathDBEupathDB:PY00104.

Phylogenomic databases

PhylomeDBQ7RT90.

Family and domain databases

InterProIPR005814. Aminotrans_3.
IPR010164. Orn_aminotrans.
IPR015424. PyrdxlP-dep_Trfase_major_dom.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR015422. PyrdxlP-dep_Trfase_major_sub2.
[Graphical view]
Gene3DG3DSA:3.40.640.10. PyrdxlP-dep_Trfase_major_sub1. 1 hit.
G3DSA:3.90.1150.10. PyrdxlP-dep_Trfase_major_sub2. 2 hits.
KOK00819.
PANTHERPTHR11986. Aminotrans_3. 1 hit.
PTHR11986:SF18. Orn_aminotrans. 1 hit.
PfamPF00202. Aminotran_3. 1 hit.
[Graphical view]
SUPFAMSSF53383. PyrdxlP-dep_Trfase_major. 1 hit.
TIGRFAMsTIGR01885. Orn_aminotrans. 1 hit.
PROSITEPS00600. AA_TRANSFER_CLASS_3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameOAT_PLAYO
AccessionPrimary (citable) accession number: Q7RT90
Entry history
Integrated into UniProtKB/Swiss-Prot: May 2, 2006
Last sequence update: December 15, 2003
Last modified: December 14, 2011
This is version 53 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

PDB cross-references

Index of Protein Data Bank (PDB) cross-references

SIMILARITY comments

Index of protein domains and families