Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Glutathione S-transferase

Gene

GST

Organism
Plasmodium yoelii yoelii
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.By similarity

Catalytic activityi

RX + glutathione = HX + R-S-glutathione.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei5GlutathioneBy similarity1

GO - Molecular functioni

Keywordsi

Molecular functionTransferase

Enzyme and pathway databases

BRENDAi2.5.1.18 4895

Names & Taxonomyi

Protein namesi
Recommended name:
Glutathione S-transferase (EC:2.5.1.18)
Gene namesi
Name:GST
ORF Names:PY05088
OrganismiPlasmodium yoelii yoelii
Taxonomic identifieri73239 [NCBI]
Taxonomic lineageiEukaryotaAlveolataApicomplexaAconoidasidaHaemosporidaPlasmodiidaePlasmodiumPlasmodium (Vinckeia)
Proteomesi
  • UP000008553 Componenti: Unassembled WGS sequence

Organism-specific databases

EuPathDBiPlasmoDB:PY05088

Pathology & Biotechi

Chemistry databases

ChEMBLiCHEMBL1741263

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002599691 – 209Glutathione S-transferaseAdd BLAST209

Interactioni

Subunit structurei

Homodimer.By similarity

Protein-protein interaction databases

STRINGi352914.XP_725489.1

Structurei

3D structure databases

ProteinModelPortaliQ7REH6
SMRiQ7REH6
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini7 – 91GST N-terminalAdd BLAST85
Domaini93 – 209GST C-terminalAdd BLAST117

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni62 – 63Glutathione bindingBy similarity2
Regioni75 – 76Glutathione bindingBy similarity2

Sequence similaritiesi

Belongs to the GST superfamily.Curated

Phylogenomic databases

eggNOGiENOG410IN5F Eukaryota
ENOG41127WC LUCA
InParanoidiQ7REH6
OMAiQKEVVSM

Family and domain databases

InterProiView protein in InterPro
IPR010987 Glutathione-S-Trfase_C-like
IPR036282 Glutathione-S-Trfase_C_sf
IPR004045 Glutathione_S-Trfase_N
IPR004046 GST_C
IPR036249 Thioredoxin-like_sf
PfamiView protein in Pfam
PF14497 GST_C_3, 1 hit
PF02798 GST_N, 1 hit
SUPFAMiSSF47616 SSF47616, 1 hit
SSF52833 SSF52833, 1 hit
PROSITEiView protein in PROSITE
PS50405 GST_CTER, 1 hit
PS50404 GST_NTER, 1 hit

Sequencei

Sequence statusi: Complete.

Q7REH6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTYLYNFFFF FFFFFSRGKA ELIRLIFAYL QVKYTDIRFG VNGDAFAEFN
60 70 80 90 100
NFKKEKEIPF NQVPILEIGG LILAQSQAIV RYLSKKYNIS GNGELNEFYA
110 120 130 140 150
DMIFCGVQDI HYKFNNTNLF KQNETTFLNE ELPKWSGYFE KLLQKNNTNY
160 170 180 190 200
FVGDTITYAD LAVFNLYDDI ESKYPNCLKN FPLLKAHIEL ISNIPNIKHY

IANRKESVY
Length:209
Mass (Da):24,693
Last modified:December 15, 2003 - v1
Checksum:iA4A7FAB3AC69CF6D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABL01001592 Genomic DNA Translation: EAA17054.1

Genome annotation databases

EnsemblProtistsiEAA17054; EAA17054; EAA17054
KEGGipyo:PY05088

Similar proteinsi

Entry informationi

Entry nameiGST_PLAYO
AccessioniPrimary (citable) accession number: Q7REH6
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 28, 2006
Last sequence update: December 15, 2003
Last modified: April 25, 2018
This is version 85 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health