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Q7REH6 (GST_PLAYO) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 63. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glutathione S-transferase

EC=2.5.1.18
Gene names
Name:GST
ORF Names:PY05088
OrganismPlasmodium yoelii yoelii [Reference proteome]
Taxonomic identifier73239 [NCBI]
Taxonomic lineageEukaryotaAlveolataApicomplexaAconoidasidaHaemosporidaPlasmodiumPlasmodium (Vinckeia)

Protein attributes

Sequence length209 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles By similarity.

Catalytic activity

RX + glutathione = HX + R-S-glutathione.

Subunit structure

Homodimer By similarity.

Sequence similarities

Belongs to the GST superfamily.

Contains 1 GST C-terminal domain.

Contains 1 GST N-terminal domain.

Ontologies

Keywords
   Molecular functionTransferase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Molecular_functionglutathione transferase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 209209Glutathione S-transferase
PRO_0000259969

Regions

Domain7 – 9185GST N-terminal
Domain93 – 209117GST C-terminal
Region62 – 632Glutathione binding By similarity
Region75 – 762Glutathione binding By similarity

Sites

Binding site51Glutathione By similarity

Sequences

Sequence LengthMass (Da)Tools
Q7REH6 [UniParc].

Last modified December 15, 2003. Version 1.
Checksum: A4A7FAB3AC69CF6D

FASTA20924,693
        10         20         30         40         50         60 
MTYLYNFFFF FFFFFSRGKA ELIRLIFAYL QVKYTDIRFG VNGDAFAEFN NFKKEKEIPF 

        70         80         90        100        110        120 
NQVPILEIGG LILAQSQAIV RYLSKKYNIS GNGELNEFYA DMIFCGVQDI HYKFNNTNLF 

       130        140        150        160        170        180 
KQNETTFLNE ELPKWSGYFE KLLQKNNTNY FVGDTITYAD LAVFNLYDDI ESKYPNCLKN 

       190        200 
FPLLKAHIEL ISNIPNIKHY IANRKESVY 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AABL01001592 Genomic DNA. Translation: EAA17054.1.
RefSeqXP_725489.1. XM_720396.1.

3D structure databases

ProteinModelPortalQ7REH6.
SMRQ7REH6. Positions 11-209.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING73239.Q7REH6.

Chemistry

ChEMBLCHEMBL1741263.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID3790828.
KEGGpyo:PY05088.

Organism-specific databases

EuPathDBPlasmoDB:PY17X_1025800.

Phylogenomic databases

eggNOGNOG05174.
KOK00799.

Family and domain databases

Gene3D1.20.1050.10. 1 hit.
3.40.30.10. 1 hit.
InterProIPR010987. Glutathione-S-Trfase_C-like.
IPR004045. Glutathione_S-Trfase_N.
IPR004046. GST_C.
IPR012336. Thioredoxin-like_fold.
[Graphical view]
PfamPF00043. GST_C. 1 hit.
PF02798. GST_N. 1 hit.
[Graphical view]
SUPFAMSSF47616. SSF47616. 1 hit.
SSF52833. SSF52833. 1 hit.
PROSITEPS50405. GST_CTER. 1 hit.
PS50404. GST_NTER. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameGST_PLAYO
AccessionPrimary (citable) accession number: Q7REH6
Entry history
Integrated into UniProtKB/Swiss-Prot: November 28, 2006
Last sequence update: December 15, 2003
Last modified: April 16, 2014
This is version 63 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)

Relevant documents

SIMILARITY comments

Index of protein domains and families