Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Q7REH6

- GST_PLAYO

UniProt

Q7REH6 - GST_PLAYO

Protein

Glutathione S-transferase

Gene

GST

Organism
Plasmodium yoelii yoelii
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 65 (01 Oct 2014)
      Sequence version 1 (15 Dec 2003)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.By similarity

    Catalytic activityi

    RX + glutathione = HX + R-S-glutathione.

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei5 – 51GlutathioneBy similarity

    GO - Molecular functioni

    1. glutathione transferase activity Source: UniProtKB-EC

    Keywords - Molecular functioni

    Transferase

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Glutathione S-transferase (EC:2.5.1.18)
    Gene namesi
    Name:GST
    ORF Names:PY05088
    OrganismiPlasmodium yoelii yoelii
    Taxonomic identifieri73239 [NCBI]
    Taxonomic lineageiEukaryotaAlveolataApicomplexaAconoidasidaHaemosporidaPlasmodiumPlasmodium (Vinckeia)
    ProteomesiUP000008553: Unassembled WGS sequence

    Organism-specific databases

    EuPathDBiPlasmoDB:PY05088.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 209209Glutathione S-transferasePRO_0000259969Add
    BLAST

    Interactioni

    Subunit structurei

    Homodimer.By similarity

    Protein-protein interaction databases

    STRINGi73239.Q7REH6.

    Structurei

    3D structure databases

    ProteinModelPortaliQ7REH6.
    SMRiQ7REH6. Positions 11-209.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini7 – 9185GST N-terminalAdd
    BLAST
    Domaini93 – 209117GST C-terminalAdd
    BLAST

    Region

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Regioni62 – 632Glutathione bindingBy similarity
    Regioni75 – 762Glutathione bindingBy similarity

    Sequence similaritiesi

    Belongs to the GST superfamily.Curated
    Contains 1 GST C-terminal domain.Curated
    Contains 1 GST N-terminal domain.Curated

    Phylogenomic databases

    eggNOGiNOG05174.
    KOiK00799.

    Family and domain databases

    Gene3Di1.20.1050.10. 1 hit.
    3.40.30.10. 1 hit.
    InterProiIPR010987. Glutathione-S-Trfase_C-like.
    IPR004045. Glutathione_S-Trfase_N.
    IPR004046. GST_C.
    IPR012336. Thioredoxin-like_fold.
    [Graphical view]
    PfamiPF00043. GST_C. 1 hit.
    PF02798. GST_N. 1 hit.
    [Graphical view]
    SUPFAMiSSF47616. SSF47616. 1 hit.
    SSF52833. SSF52833. 1 hit.
    PROSITEiPS50405. GST_CTER. 1 hit.
    PS50404. GST_NTER. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q7REH6-1 [UniParc]FASTAAdd to Basket

    « Hide

    MTYLYNFFFF FFFFFSRGKA ELIRLIFAYL QVKYTDIRFG VNGDAFAEFN    50
    NFKKEKEIPF NQVPILEIGG LILAQSQAIV RYLSKKYNIS GNGELNEFYA 100
    DMIFCGVQDI HYKFNNTNLF KQNETTFLNE ELPKWSGYFE KLLQKNNTNY 150
    FVGDTITYAD LAVFNLYDDI ESKYPNCLKN FPLLKAHIEL ISNIPNIKHY 200
    IANRKESVY 209
    Length:209
    Mass (Da):24,693
    Last modified:December 15, 2003 - v1
    Checksum:iA4A7FAB3AC69CF6D
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AABL01001592 Genomic DNA. Translation: EAA17054.1.
    RefSeqiXP_725489.1. XM_720396.1.

    Genome annotation databases

    GeneIDi3790828.
    KEGGipyo:PY05088.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AABL01001592 Genomic DNA. Translation: EAA17054.1 .
    RefSeqi XP_725489.1. XM_720396.1.

    3D structure databases

    ProteinModelPortali Q7REH6.
    SMRi Q7REH6. Positions 11-209.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 73239.Q7REH6.

    Chemistry

    ChEMBLi CHEMBL1741263.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 3790828.
    KEGGi pyo:PY05088.

    Organism-specific databases

    EuPathDBi PlasmoDB:PY05088.

    Phylogenomic databases

    eggNOGi NOG05174.
    KOi K00799.

    Family and domain databases

    Gene3Di 1.20.1050.10. 1 hit.
    3.40.30.10. 1 hit.
    InterProi IPR010987. Glutathione-S-Trfase_C-like.
    IPR004045. Glutathione_S-Trfase_N.
    IPR004046. GST_C.
    IPR012336. Thioredoxin-like_fold.
    [Graphical view ]
    Pfami PF00043. GST_C. 1 hit.
    PF02798. GST_N. 1 hit.
    [Graphical view ]
    SUPFAMi SSF47616. SSF47616. 1 hit.
    SSF52833. SSF52833. 1 hit.
    PROSITEi PS50405. GST_CTER. 1 hit.
    PS50404. GST_NTER. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: 17XNL.

    Entry informationi

    Entry nameiGST_PLAYO
    AccessioniPrimary (citable) accession number: Q7REH6
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: November 28, 2006
    Last sequence update: December 15, 2003
    Last modified: October 1, 2014
    This is version 65 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3