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Q7QIL8 (EIF3E_ANOGA) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 68. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Eukaryotic translation initiation factor 3 subunit E

Short name=eIF3e
Alternative name(s):
Eukaryotic translation initiation factor 3 subunit 6
Gene names
Name:eIF3-S6
ORF Names:AGAP006944
OrganismAnopheles gambiae (African malaria mosquito) [Reference proteome]
Taxonomic identifier7165 [NCBI]
Taxonomic lineageEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraNematoceraCulicoideaCulicidaeAnophelinaeAnopheles

Protein attributes

Sequence length433 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome By similarity. HAMAP-Rule MF_03004

Subunit structure

Component of the eukaryotic translation initiation factor 3 (eIF-3) complex By similarity.

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_03004.

Sequence similarities

Belongs to the eIF-3 subunit E family.

Contains 1 PCI domain.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 433433Eukaryotic translation initiation factor 3 subunit E HAMAP-Rule MF_03004
PRO_0000365960

Regions

Domain282 – 387106PCI

Sequences

Sequence LengthMass (Da)Tools
Q7QIL8 [UniParc].

Last modified December 7, 2004. Version 2.
Checksum: 675D52209410A7F0

FASTA43350,489
        10         20         30         40         50         60 
MAKFDLTAKN CQYLDRHLTF PLLEFLLQKK VFDQTSLLKF ILETVSKTNM VDYKHDIRER 

        70         80         90        100        110        120 
LAMDKVHPDE LAQGRANVLA TLKELQAEVA PLMKCMEELK NPDSTKDSKS VIHALQQTLD 

       130        140        150        160        170        180 
YDIILSAQKL AKYLYECGNY NDSLSYLYVC MLVMEPNDKN YLGVLWGKLA VEILTLNWQT 

       190        200        210        220        230        240 
ALEDLTRLRD FIENYNFSPI QVLQQRAWLI HWSVLVFFNH GKGRDLIIDM FLYKPQYLNA 

       250        260        270        280        290        300 
IQTMCPHILR YLATAVIINR GRRNALKDLI KVIQQESYTY RDPITEFLEH LYVNFDFEGA 

       310        320        330        340        350        360 
RKKLHECQTV IVNDFFIIGC LTEFVENARL MIFETFCRIH QCITIGMLAD KLNMKPDEAE 

       370        380        390        400        410        420 
CWIVNLIRNA RLDAKIDSKL GHVVMGTQPL SPYQQLVEKI DSLSVRSEAL TLLVERKHKA 

       430 
KTQEAGEGHW KYY 

« Hide

References

[1]"The genome sequence of the malaria mosquito Anopheles gambiae."
Holt R.A., Subramanian G.M., Halpern A., Sutton G.G., Charlab R., Nusskern D.R., Wincker P., Clark A.G., Ribeiro J.M.C., Wides R., Salzberg S.L., Loftus B.J., Yandell M.D., Majoros W.H., Rusch D.B., Lai Z., Kraft C.L., Abril J.F. expand/collapse author list , Anthouard V., Arensburger P., Atkinson P.W., Baden H., de Berardinis V., Baldwin D., Benes V., Biedler J., Blass C., Bolanos R., Boscus D., Barnstead M., Cai S., Center A., Chaturverdi K., Christophides G.K., Chrystal M.A.M., Clamp M., Cravchik A., Curwen V., Dana A., Delcher A., Dew I., Evans C.A., Flanigan M., Grundschober-Freimoser A., Friedli L., Gu Z., Guan P., Guigo R., Hillenmeyer M.E., Hladun S.L., Hogan J.R., Hong Y.S., Hoover J., Jaillon O., Ke Z., Kodira C.D., Kokoza E., Koutsos A., Letunic I., Levitsky A.A., Liang Y., Lin J.-J., Lobo N.F., Lopez J.R., Malek J.A., McIntosh T.C., Meister S., Miller J.R., Mobarry C., Mongin E., Murphy S.D., O'Brochta D.A., Pfannkoch C., Qi R., Regier M.A., Remington K., Shao H., Sharakhova M.V., Sitter C.D., Shetty J., Smith T.J., Strong R., Sun J., Thomasova D., Ton L.Q., Topalis P., Tu Z.J., Unger M.F., Walenz B., Wang A.H., Wang J., Wang M., Wang X., Woodford K.J., Wortman J.R., Wu M., Yao A., Zdobnov E.M., Zhang H., Zhao Q., Zhao S., Zhu S.C., Zhimulev I., Coluzzi M., della Torre A., Roth C.W., Louis C., Kalush F., Mural R.J., Myers E.W., Adams M.D., Smith H.O., Broder S., Gardner M.J., Fraser C.M., Birney E., Bork P., Brey P.T., Venter J.C., Weissenbach J., Kafatos F.C., Collins F.H., Hoffman S.L.
Science 298:129-149(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: PEST.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AAAB01008807 Genomic DNA. Translation: EAA04727.2.
RefSeqXP_308812.2. XM_308812.4.

3D structure databases

ProteinModelPortalQ7QIL8.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING7165.AGAP006944-PA.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaAGAP006944-RA; AGAP006944-PA; AGAP006944.
GeneID1270140.
KEGGaga:AgaP_AGAP006944.
VectorBaseAGAP006944. Anopheles gambiae.

Phylogenomic databases

eggNOGNOG324642.
HOGENOMHOG000036697.
OMAHNASEED.
OrthoDBEOG7QNVKP.
PhylomeDBQ7QIL8.

Family and domain databases

Gene3D1.10.10.10. 1 hit.
HAMAPMF_03004. eIF3e.
InterProIPR016650. eIF3e.
IPR019010. eIF3e_N.
IPR000717. PCI_dom.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PANTHERPTHR10317. PTHR10317. 1 hit.
PfamPF09440. eIF3_N. 1 hit.
PF01399. PCI. 1 hit.
[Graphical view]
PIRSFPIRSF016255. eIF3e_su6. 1 hit.
SMARTSM00088. PINT. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameEIF3E_ANOGA
AccessionPrimary (citable) accession number: Q7QIL8
Entry history
Integrated into UniProtKB/Swiss-Prot: March 3, 2009
Last sequence update: December 7, 2004
Last modified: July 9, 2014
This is version 68 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)

Relevant documents

SIMILARITY comments

Index of protein domains and families

Translation initiation factors

List of translation initiation factor entries