Q7QHI0 (Q7QHI0_ANOGA) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
AGAP011192-PA EMBL EAA05242.4

Gene names

ORF Names:

AGAP011192, AgaP_AGAP011192 EMBL EAA05242.4

Organism

Anopheles gambiae (African malaria mosquito) [Reference proteome]

Taxonomic identifier

7165 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Protostomia › Ecdysozoa › Panarthropoda › Arthropoda › Mandibulata › Pancrustacea › Hexapoda › Insecta › Dicondylia › Pterygota › Neoptera › Endopterygota › Diptera › Nematocera › Culicimorpha › Culicoidea › Culicidae › Anophelinae › Anopheles › Cellia › Pyretophorus › gambiae species complex

Protein attributes

Sequence length	2808 AA.
Sequence status	Complete.
Protein existence	Predicted

General annotation (Comments)

Catalytic activity	S-adenosyl-L-methionine + L-lysine-[histone] = S-adenosyl-L-homocysteine + N(6)-methyl-L-lysine-[histone]. SAAS SAAS001214
Sequence similarities	Contains 1 SET domain. RuleBase RU004538 Contains 1 post-SET domain. RuleBase RU004541 SAAS SAAS001214
Caution	The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. EMBL EAA05242.4

Ontologies

Keywords
Cellular component	Nucleus SAAS SAAS003616
Molecular function	Methyltransferase RuleBase RU004541 SAAS SAAS001214 Transferase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Cellular_component	nucleus Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	methyltransferase activity Inferred from electronic annotation. Source: UniProtKB-KW zinc ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q7QHI0 [UniParc]. Last modified October 23, 2007. Version 4. Checksum: 221CE93A05BF7B85	FASTA	2,808	298,729
	10 20 30 40 50 60 MVGGGLINQI PKNTMVAMTT PAPSAAGSPQ TADPSGSKTI PLFQANLQPQ PPQPPETIAT 70 80 90 100 110 120 EQDRLLQINY ENWLNQQNTV LSNQLKYYET EIVKLRKVKK QLNTKQRHLR KQGNELTEND 130 140 150 160 170 180 AKELQKITAD HTVIQKQLEN ARRQQRQHSV ILQEYKTKHQ SGKPASSGAS TPVGAPGSSP 190 200 210 220 230 240 AQSLIAPPSP LMSPSPSSQP GSLYQPTVQS PLSNLILQPN QSPLHSPSPL LSHSPGPASV 250 260 270 280 290 300 NSSVLQSPGG NHTNSNSAMS PYSTMQPSPR IGTPHSQIDE NPFSPGPGGG PSPSPSLPGR 310 320 330 340 350 360 LTSPAPRMTS PQHRMAGQQM VVGGPPHGPQ PGQSFGYIKL GLRGGSPMWG NARGNKRANP 370 380 390 400 410 420 VRKQTINTAG TLVPHRNRIT IVQKPAGGIT TTTTTLNTVG VTIKPVGGGT EPATAISSGA 430 440 450 460 470 480 SGSGTVEEIV VIDSSPDEKQ QRLLDYDDDN DKALVGTEVS LNSVAQHGVD GDEAIMESFG 490 500 510 520 530 540 SGTPAGYDIV GSPLDSQIAA GEYNLFSDDV VECVDSEDGG VTAGGAKKDA RTVAVELLLD 550 560 570 580 590 600 ADSSAKDKPL LGSSEIEIVE SIDESSIGTT AEDFEAMIDS RPKTATPPTV AADGAPSAAK 610 620 630 640 650 660 TEPTVTVTRK EEKVVEKVAT PKKEVTLVTV HQQQQQQSPK PISYPTARIA IQQSLMQNRP 670 680 690 700 710 720 IVSAAHQRLV KDATESTAKL SIGNTTISVP ILKSFPMTAT PSKAAGTEQN AASKAATLAT 730 740 750 760 770 780 HSKKLINTSG GLSISNISKN PAGGTVIAVG GQKINTTSIV TLSSLNLNQS SPFITKTFAR 790 800 810 820 830 840 HGGGLTIQQQ KQLSVGSQIK IQQAGSVVLQ QQQQQQQSAQ PTATSSGANA TSPKPKVAST 850 860 870 880 890 900 SSLSYAKLSS LTVTQDTSLP TKIFEDDSIS PDSSISQEDA EQPALDKSDL AGPAEEAAAP 910 920 930 940 950 960 KTTSTETPGG LDTPATTAET TQQPDGQSVK GKQNIIPVHV IAKSRENSRS PILTGAGGQR 970 980 990 1000 1010 1020 IVSSIPQLSP LSQPNELTLN AMNVSQQVRS IMSSISVSNA ASVAGSSSAG GGGTPSVVLS 1030 1040 1050 1060 1070 1080 MAPSTTTAAG TTSVASSVAA SNISTITFDT ILPSKGDNMS KTETIASILK TVSGKTILPA 1090 1100 1110 1120 1130 1140 AAIASNSNLV KASEQQSGSP SLTSTTITQI PATKLITQQL QLSRLPGQTI GSGNSNFLVV 1150 1160 1170 1180 1190 1200 KQLRTPNKQT GQNHMQKQLV VLTQQGQGGQ QIKLQTHQTQ QLAAGNSVII QSQPGSSGGA 1210 1220 1230 1240 1250 1260 TGSFMKISTT PTIVSTAAGG GDTASSKSVT TTVDTTSASG IATILNNANA QQQQQKTLTT 1270 1280 1290 1300 1310 1320 SQQPAAQLQS STSRAATITS INVTSTTATP VASILSATLS QPLIKTSSHM PSSITTLLQS 1330 1340 1350 1360 1370 1380 QLQSAASFRR SKSTDEAPAH GHGRETASQI LSKRLSLEST NVVKSEPVDS ASDDASVSSS 1390 1400 1410 1420 1430 1440 TAQAASSTGC KFSTMPSAGT VAKSEDSQNV LLKQLLQNSG SSSASSVSSP APSPIGRAVP 1450 1460 1470 1480 1490 1500 SLITSQRAPS LGVVSSLEAQ LARPVIPPSA NPPAIQLISS QPIPAIAASI SSISSSTVST 1510 1520 1530 1540 1550 1560 AAAASTPSAA LMSPSGISSS HPTPNLAANM LAASMKKEEM LQAAAAAAAT TITTTTTTSG 1570 1580 1590 1600 1610 1620 ATVGQGTVKL DSGTITVTQL QASQPTVTTA AASQQLQTTV TAAKSAMPPQ QQQVNSLQFT 1630 1640 1650 1660 1670 1680 QQNNQLQSKT LPNAATVQQI GDTTIVRTPT PTPSPGPMQQ PSRPPSAAPR SETPVDIKKE 1690 1700 1710 1720 1730 1740 PEQSLNSGSA SVASATTTTS TVGGPSPVST VPTATAIKEE PTEPLTAEQA AKRAAELALE 1750 1760 1770 1780 1790 1800 LKKKKRREYQ KNRRQMQIQS NKDNAHSQAK KKPKKSVKIE EDYDTCIDNL MGQLRQLPQM 1810 1820 1830 1840 1850 1860 QILEPQLPRN YGVCSVFGTG DLSKFTNLKG YSIATGDLTG RYGDAQIPSI ADFYNTKPFG 1870 1880 1890 1900 1910 1920 VKDPPPEPTP VSVHRGFYDQ EFAPIKFETE DRQRYEFVRD RDLDSPDTII STSSPECLRW 1930 1940 1950 1960 1970 1980 DSPVSFPGLR LIKEEPAEDE QTAVYRQMSP VIPILAPIPI RLRKGFTLSA DSAGRPQQGA 1990 2000 2010 2020 2030 2040 NVAGSNKENE GFRETAGVKS RFGPPTPLKD TSNVTVTLTL TSSAVDDIFG VLRDLANMLE 2050 2060 2070 2080 2090 2100 IPPPTTYQIV ERTVSPTSQK LGLYRTKGRD GKEGAPIDIQ TILNGSARFC RHCDVVILSN 2110 2120 2130 2140 2150 2160 IIIANASEFP LLAANGDVGG QAELESEELY FCGEQCYRQF RCCPTSILDE AGDSSAGAAA 2170 2180 2190 2200 2210 2220 LATGEGTAAL SHKPDTGAPN VDVAAVSGAV EIKQEVLEDV EMEDVTAGNS STGSVKDAPG 2230 2240 2250 2260 2270 2280 SGERKKKHPD DGVEVDVLAG APPTKQMKGV RYKVYTPNCF GVQRFKKPSE KEITETLFRM 2290 2300 2310 2320 2330 2340 SITVAPTPKM PDDTRRCIFC HTVGDGVADG PSRLLNYDVD KWVHLNCALW SDGVYETVNG 2350 2360 2370 2380 2390 2400 ALMNLENALQ QSLTSVCAFC STLGATVKCF KTRCANVYHL SCAMKDSCVF YKNKTTMCQT 2410 2420 2430 2440 2450 2460 HAPKTEKDSE LTTLSVQRRV YVDRDESRQV ASVMHHSESN NLLRVGSLIF LNVGQLLPHQ 2470 2480 2490 2500 2510 2520 LQSFHTPNYI YPIGYKIIRF YWSMRRPNKR CRYICSIADV CGRPEFRVLV QETAEEDIEL 2530 2540 2550 2560 2570 2580 RDATPKAVWQ RILEPMAQLR KSCQIVQLFP KYISGEDLFG LTEPAVVRIL ESLPGIETLT 2590 2600 2610 2620 2630 2640 DYRFKYGRNP LLELPLAINP SGAARTEPKL KHTLSWKKPH TQRTGSVSQR PTFVPTSSPA 2650 2660 2670 2680 2690 2700 GEVACPYSKQ FVHSKSSQYK KMKQEWRNNV FLARSKIQGL GLYAARDLEK HTMVIEYIGE 2710 2720 2730 2740 2750 2760 VIRTEVSEMR EKQYEARNRG IYMFRLDEER VVDATLSGGL ARYINHSCNP NCVTEIVEVD 2770 2780 2790 2800 RELRIIIFAK RRINRGEELS YDYKFDIEDD AHKISCMCGA PNCKKWMN

References

[1]

"The genome sequence of the malaria mosquito Anopheles gambiae." Holt R.A., Subramanian G.M., Halpern A., Sutton G.G., Charlab R., Nusskern D.R., Wincker P., Clark A.G., Ribeiro J.M.C., Wides R., Salzberg S.L., Loftus B.J., Yandell M.D., Majoros W.H., Rusch D.B., Lai Z., Kraft C.L., Abril J.F. , Anthouard V., Arensburger P., Atkinson P.W., Baden H., de Berardinis V., Baldwin D., Benes V., Biedler J., Blass C., Bolanos R., Boscus D., Barnstead M., Cai S., Center A., Chaturverdi K., Christophides G.K., Chrystal M.A.M., Clamp M., Cravchik A., Curwen V., Dana A., Delcher A., Dew I., Evans C.A., Flanigan M., Grundschober-Freimoser A., Friedli L., Gu Z., Guan P., Guigo R., Hillenmeyer M.E., Hladun S.L., Hogan J.R., Hong Y.S., Hoover J., Jaillon O., Ke Z., Kodira C.D., Kokoza E., Koutsos A., Letunic I., Levitsky A.A., Liang Y., Lin J.-J., Lobo N.F., Lopez J.R., Malek J.A., McIntosh T.C., Meister S., Miller J.R., Mobarry C., Mongin E., Murphy S.D., O'Brochta D.A., Pfannkoch C., Qi R., Regier M.A., Remington K., Shao H., Sharakhova M.V., Sitter C.D., Shetty J., Smith T.J., Strong R., Sun J., Thomasova D., Ton L.Q., Topalis P., Tu Z.J., Unger M.F., Walenz B., Wang A.H., Wang J., Wang M., Wang X., Woodford K.J., Wortman J.R., Wu M., Yao A., Zdobnov E.M., Zhang H., Zhao Q., Zhao S., Zhu S.C., Zhimulev I., Coluzzi M., della Torre A., Roth C.W., Louis C., Kalush F., Mural R.J., Myers E.W., Adams M.D., Smith H.O., Broder S., Gardner M.J., Fraser C.M., Birney E., Bork P., Brey P.T., Venter J.C., Weissenbach J., Kafatos F.C., Collins F.H., Hoffman S.L. Science 298:129-149(2002) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: PEST EMBL EAA05242.4.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AAAB01008816 Genomic DNA. Translation: EAA05242.4.
RefSeq	XP_309452.4. XM_309452.5.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblMetazoa	AGAP011192-RA; AGAP011192-PA; AGAP011192.
GeneID	1270733.
KEGG	aga:AgaP_AGAP011192.
VectorBase	AGAP011192. Anopheles gambiae.
Phylogenomic databases
eggNOG	COG2940.
HOGENOM	HOG000046712.
KO	K09188.
OMA	FLARSKI.
OrthoDB	EOG4G79D5.
PhylomeDB	Q7QHI0.
Family and domain databases
InterPro	IPR003889. FYrich_C. IPR003888. FYrich_N. IPR003616. Post-SET_dom. IPR001214. SET_dom. IPR001965. Znf_PHD. [Graphical view]
Pfam	PF05965. FYRC. 1 hit. PF05964. FYRN. 1 hit. PF00856. SET. 1 hit. [Graphical view]
SMART	SM00542. FYRC. 1 hit. SM00541. FYRN. 1 hit. SM00249. PHD. 1 hit. SM00508. PostSET. 1 hit. SM00317. SET. 1 hit. [Graphical view]
PROSITE	PS51543. FYRC. 1 hit. PS51542. FYRN. 1 hit. PS50868. POST_SET. 1 hit. PS50280. SET. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q7QHI0_ANOGA

Accession

Primary (citable) accession number: Q7QHI0

Entry history

Integrated into UniProtKB/TrEMBL:	December 15, 2003
Last sequence update:	October 23, 2007
Last modified:	May 1, 2013
This is version 60 of the entry and version 4 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)