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Q7QHI0

- Q7QHI0_ANOGA

UniProt

Q7QHI0 - Q7QHI0_ANOGA

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Protein
Submitted name:

AGAP011192-PA

Gene

AgaP_AGAP011192

Organism
Anopheles gambiae (African malaria mosquito)
Status
Unreviewed - Annotation score: 1 out of 5- Protein predictedi

Functioni

Catalytic activityi

S-adenosyl-L-methionine + L-lysine-[histone] = S-adenosyl-L-homocysteine + N(6)-methyl-L-lysine-[histone].SAAS annotation

GO - Molecular functioni

  1. methyltransferase activity Source: UniProtKB-KW
  2. zinc ion binding Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

MethyltransferaseUniRule annotationSAAS annotation, Transferase

Keywords - Ligandi

S-adenosyl-L-methionineSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
AGAP011192-PAImported
Gene namesi
ORF Names:AgaP_AGAP011192Imported
OrganismiAnopheles gambiae (African malaria mosquito)Imported
Taxonomic identifieri7165 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraNematoceraCulicoideaCulicidaeAnophelinaeAnopheles
ProteomesiUP000007062: Chromosome 3L

Subcellular locationi

GO - Cellular componenti

  1. nucleus Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

NucleusSAAS annotation

Interactioni

Protein-protein interaction databases

STRINGi7165.AGAP011192-PA.

Family & Domainsi

Sequence similaritiesi

Contains 1 SET domain.UniRule annotation
Contains SET domain.SAAS annotation
Contains post-SET domain.SAAS annotation

Phylogenomic databases

eggNOGiCOG2940.
HOGENOMiHOG000046712.
InParanoidiQ7QHI0.
KOiK09188.
OMAiFLARSKI.
OrthoDBiEOG7QZG8S.
PhylomeDBiQ7QHI0.

Family and domain databases

InterProiIPR003889. FYrich_C.
IPR003888. FYrich_N.
IPR003616. Post-SET_dom.
IPR001214. SET_dom.
IPR001965. Znf_PHD.
[Graphical view]
PfamiPF05965. FYRC. 1 hit.
PF05964. FYRN. 1 hit.
PF00856. SET. 1 hit.
[Graphical view]
SMARTiSM00542. FYRC. 1 hit.
SM00541. FYRN. 1 hit.
SM00249. PHD. 1 hit.
SM00508. PostSET. 1 hit.
SM00317. SET. 1 hit.
[Graphical view]
PROSITEiPS51543. FYRC. 1 hit.
PS51542. FYRN. 1 hit.
PS50868. POST_SET. 1 hit.
PS50280. SET. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q7QHI0-1 [UniParc]FASTAAdd to Basket

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        10         20         30         40         50
MVGGGLINQI PKNTMVAMTT PAPSAAGSPQ TADPSGSKTI PLFQANLQPQ
60 70 80 90 100
PPQPPETIAT EQDRLLQINY ENWLNQQNTV LSNQLKYYET EIVKLRKVKK
110 120 130 140 150
QLNTKQRHLR KQGNELTEND AKELQKITAD HTVIQKQLEN ARRQQRQHSV
160 170 180 190 200
ILQEYKTKHQ SGKPASSGAS TPVGAPGSSP AQSLIAPPSP LMSPSPSSQP
210 220 230 240 250
GSLYQPTVQS PLSNLILQPN QSPLHSPSPL LSHSPGPASV NSSVLQSPGG
260 270 280 290 300
NHTNSNSAMS PYSTMQPSPR IGTPHSQIDE NPFSPGPGGG PSPSPSLPGR
310 320 330 340 350
LTSPAPRMTS PQHRMAGQQM VVGGPPHGPQ PGQSFGYIKL GLRGGSPMWG
360 370 380 390 400
NARGNKRANP VRKQTINTAG TLVPHRNRIT IVQKPAGGIT TTTTTLNTVG
410 420 430 440 450
VTIKPVGGGT EPATAISSGA SGSGTVEEIV VIDSSPDEKQ QRLLDYDDDN
460 470 480 490 500
DKALVGTEVS LNSVAQHGVD GDEAIMESFG SGTPAGYDIV GSPLDSQIAA
510 520 530 540 550
GEYNLFSDDV VECVDSEDGG VTAGGAKKDA RTVAVELLLD ADSSAKDKPL
560 570 580 590 600
LGSSEIEIVE SIDESSIGTT AEDFEAMIDS RPKTATPPTV AADGAPSAAK
610 620 630 640 650
TEPTVTVTRK EEKVVEKVAT PKKEVTLVTV HQQQQQQSPK PISYPTARIA
660 670 680 690 700
IQQSLMQNRP IVSAAHQRLV KDATESTAKL SIGNTTISVP ILKSFPMTAT
710 720 730 740 750
PSKAAGTEQN AASKAATLAT HSKKLINTSG GLSISNISKN PAGGTVIAVG
760 770 780 790 800
GQKINTTSIV TLSSLNLNQS SPFITKTFAR HGGGLTIQQQ KQLSVGSQIK
810 820 830 840 850
IQQAGSVVLQ QQQQQQQSAQ PTATSSGANA TSPKPKVAST SSLSYAKLSS
860 870 880 890 900
LTVTQDTSLP TKIFEDDSIS PDSSISQEDA EQPALDKSDL AGPAEEAAAP
910 920 930 940 950
KTTSTETPGG LDTPATTAET TQQPDGQSVK GKQNIIPVHV IAKSRENSRS
960 970 980 990 1000
PILTGAGGQR IVSSIPQLSP LSQPNELTLN AMNVSQQVRS IMSSISVSNA
1010 1020 1030 1040 1050
ASVAGSSSAG GGGTPSVVLS MAPSTTTAAG TTSVASSVAA SNISTITFDT
1060 1070 1080 1090 1100
ILPSKGDNMS KTETIASILK TVSGKTILPA AAIASNSNLV KASEQQSGSP
1110 1120 1130 1140 1150
SLTSTTITQI PATKLITQQL QLSRLPGQTI GSGNSNFLVV KQLRTPNKQT
1160 1170 1180 1190 1200
GQNHMQKQLV VLTQQGQGGQ QIKLQTHQTQ QLAAGNSVII QSQPGSSGGA
1210 1220 1230 1240 1250
TGSFMKISTT PTIVSTAAGG GDTASSKSVT TTVDTTSASG IATILNNANA
1260 1270 1280 1290 1300
QQQQQKTLTT SQQPAAQLQS STSRAATITS INVTSTTATP VASILSATLS
1310 1320 1330 1340 1350
QPLIKTSSHM PSSITTLLQS QLQSAASFRR SKSTDEAPAH GHGRETASQI
1360 1370 1380 1390 1400
LSKRLSLEST NVVKSEPVDS ASDDASVSSS TAQAASSTGC KFSTMPSAGT
1410 1420 1430 1440 1450
VAKSEDSQNV LLKQLLQNSG SSSASSVSSP APSPIGRAVP SLITSQRAPS
1460 1470 1480 1490 1500
LGVVSSLEAQ LARPVIPPSA NPPAIQLISS QPIPAIAASI SSISSSTVST
1510 1520 1530 1540 1550
AAAASTPSAA LMSPSGISSS HPTPNLAANM LAASMKKEEM LQAAAAAAAT
1560 1570 1580 1590 1600
TITTTTTTSG ATVGQGTVKL DSGTITVTQL QASQPTVTTA AASQQLQTTV
1610 1620 1630 1640 1650
TAAKSAMPPQ QQQVNSLQFT QQNNQLQSKT LPNAATVQQI GDTTIVRTPT
1660 1670 1680 1690 1700
PTPSPGPMQQ PSRPPSAAPR SETPVDIKKE PEQSLNSGSA SVASATTTTS
1710 1720 1730 1740 1750
TVGGPSPVST VPTATAIKEE PTEPLTAEQA AKRAAELALE LKKKKRREYQ
1760 1770 1780 1790 1800
KNRRQMQIQS NKDNAHSQAK KKPKKSVKIE EDYDTCIDNL MGQLRQLPQM
1810 1820 1830 1840 1850
QILEPQLPRN YGVCSVFGTG DLSKFTNLKG YSIATGDLTG RYGDAQIPSI
1860 1870 1880 1890 1900
ADFYNTKPFG VKDPPPEPTP VSVHRGFYDQ EFAPIKFETE DRQRYEFVRD
1910 1920 1930 1940 1950
RDLDSPDTII STSSPECLRW DSPVSFPGLR LIKEEPAEDE QTAVYRQMSP
1960 1970 1980 1990 2000
VIPILAPIPI RLRKGFTLSA DSAGRPQQGA NVAGSNKENE GFRETAGVKS
2010 2020 2030 2040 2050
RFGPPTPLKD TSNVTVTLTL TSSAVDDIFG VLRDLANMLE IPPPTTYQIV
2060 2070 2080 2090 2100
ERTVSPTSQK LGLYRTKGRD GKEGAPIDIQ TILNGSARFC RHCDVVILSN
2110 2120 2130 2140 2150
IIIANASEFP LLAANGDVGG QAELESEELY FCGEQCYRQF RCCPTSILDE
2160 2170 2180 2190 2200
AGDSSAGAAA LATGEGTAAL SHKPDTGAPN VDVAAVSGAV EIKQEVLEDV
2210 2220 2230 2240 2250
EMEDVTAGNS STGSVKDAPG SGERKKKHPD DGVEVDVLAG APPTKQMKGV
2260 2270 2280 2290 2300
RYKVYTPNCF GVQRFKKPSE KEITETLFRM SITVAPTPKM PDDTRRCIFC
2310 2320 2330 2340 2350
HTVGDGVADG PSRLLNYDVD KWVHLNCALW SDGVYETVNG ALMNLENALQ
2360 2370 2380 2390 2400
QSLTSVCAFC STLGATVKCF KTRCANVYHL SCAMKDSCVF YKNKTTMCQT
2410 2420 2430 2440 2450
HAPKTEKDSE LTTLSVQRRV YVDRDESRQV ASVMHHSESN NLLRVGSLIF
2460 2470 2480 2490 2500
LNVGQLLPHQ LQSFHTPNYI YPIGYKIIRF YWSMRRPNKR CRYICSIADV
2510 2520 2530 2540 2550
CGRPEFRVLV QETAEEDIEL RDATPKAVWQ RILEPMAQLR KSCQIVQLFP
2560 2570 2580 2590 2600
KYISGEDLFG LTEPAVVRIL ESLPGIETLT DYRFKYGRNP LLELPLAINP
2610 2620 2630 2640 2650
SGAARTEPKL KHTLSWKKPH TQRTGSVSQR PTFVPTSSPA GEVACPYSKQ
2660 2670 2680 2690 2700
FVHSKSSQYK KMKQEWRNNV FLARSKIQGL GLYAARDLEK HTMVIEYIGE
2710 2720 2730 2740 2750
VIRTEVSEMR EKQYEARNRG IYMFRLDEER VVDATLSGGL ARYINHSCNP
2760 2770 2780 2790 2800
NCVTEIVEVD RELRIIIFAK RRINRGEELS YDYKFDIEDD AHKISCMCGA

PNCKKWMN
Length:2,808
Mass (Da):298,729
Last modified:October 23, 2007 - v4
Checksum:i221CE93A05BF7B85
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AAAB01008816 Genomic DNA. Translation: EAA05242.4.
RefSeqiXP_309452.4. XM_309452.5.

Genome annotation databases

EnsemblMetazoaiAGAP011192-RA; AGAP011192-PA; AGAP011192.
GeneIDi1270733.
KEGGiaga:AgaP_AGAP011192.
VectorBaseiAGAP011192. Anopheles gambiae.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AAAB01008816 Genomic DNA. Translation: EAA05242.4 .
RefSeqi XP_309452.4. XM_309452.5.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 7165.AGAP011192-PA.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblMetazoai AGAP011192-RA ; AGAP011192-PA ; AGAP011192 .
GeneIDi 1270733.
KEGGi aga:AgaP_AGAP011192.
VectorBasei AGAP011192. Anopheles gambiae.

Phylogenomic databases

eggNOGi COG2940.
HOGENOMi HOG000046712.
InParanoidi Q7QHI0.
KOi K09188.
OMAi FLARSKI.
OrthoDBi EOG7QZG8S.
PhylomeDBi Q7QHI0.

Family and domain databases

InterProi IPR003889. FYrich_C.
IPR003888. FYrich_N.
IPR003616. Post-SET_dom.
IPR001214. SET_dom.
IPR001965. Znf_PHD.
[Graphical view ]
Pfami PF05965. FYRC. 1 hit.
PF05964. FYRN. 1 hit.
PF00856. SET. 1 hit.
[Graphical view ]
SMARTi SM00542. FYRC. 1 hit.
SM00541. FYRN. 1 hit.
SM00249. PHD. 1 hit.
SM00508. PostSET. 1 hit.
SM00317. SET. 1 hit.
[Graphical view ]
PROSITEi PS51543. FYRC. 1 hit.
PS51542. FYRN. 1 hit.
PS50868. POST_SET. 1 hit.
PS50280. SET. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "The genome sequence of the malaria mosquito Anopheles gambiae."
    Holt R.A., Subramanian G.M., Halpern A., Sutton G.G., Charlab R., Nusskern D.R., Wincker P., Clark A.G., Ribeiro J.M., Wides R., Salzberg S.L., Loftus B., Yandell M., Majoros W.H., Rusch D.B., Lai Z., Kraft C.L., Abril J.F.
    , Anthouard V., Arensburger P., Atkinson P.W., Baden H., de Berardinis V., Baldwin D., Benes V., Biedler J., Blass C., Bolanos R., Boscus D., Barnstead M., Cai S., Center A., Chaturverdi K., Christophides G.K., Chrystal M.A., Clamp M., Cravchik A., Curwen V., Dana A., Delcher A., Dew I., Evans C.A., Flanigan M., Grundschober-Freimoser A., Friedli L., Gu Z., Guan P., Guigo R., Hillenmeyer M.E., Hladun S.L., Hogan J.R., Hong Y.S., Hoover J., Jaillon O., Ke Z., Kodira C., Kokoza E., Koutsos A., Letunic I., Levitsky A., Liang Y., Lin J.J., Lobo N.F., Lopez J.R., Malek J.A., McIntosh T.C., Meister S., Miller J., Mobarry C., Mongin E., Murphy S.D., O'Brochta D.A., Pfannkoch C., Qi R., Regier M.A., Remington K., Shao H., Sharakhova M.V., Sitter C.D., Shetty J., Smith T.J., Strong R., Sun J., Thomasova D., Ton L.Q., Topalis P., Tu Z., Unger M.F., Walenz B., Wang A., Wang J., Wang M., Wang X., Woodford K.J., Wortman J.R., Wu M., Yao A., Zdobnov E.M., Zhang H., Zhao Q., Zhao S., Zhu S.C., Zhimulev I., Coluzzi M., della Torre A., Roth C.W., Louis C., Kalush F., Mural R.J., Myers E.W., Adams M.D., Smith H.O., Broder S., Gardner M.J., Fraser C.M., Birney E., Bork P., Brey P.T., Venter J.C., Weissenbach J., Kafatos F.C., Collins F.H., Hoffman S.L.
    Science 298:129-149(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: PESTImported.

Entry informationi

Entry nameiQ7QHI0_ANOGA
AccessioniPrimary (citable) accession number: Q7QHI0
Entry historyi
Integrated into UniProtKB/TrEMBL: December 15, 2003
Last sequence update: October 23, 2007
Last modified: October 29, 2014
This is version 70 of the entry and version 4 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3