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Q7QFC8

- Q7QFC8_ANOGA

UniProt

Q7QFC8 - Q7QFC8_ANOGA

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Protein
Submitted name:

AGAP000410-PA

Gene

AgaP_AGAP000410

Organism
Anopheles gambiae (African malaria mosquito)
Status
Unreviewed - Annotation score: 1 out of 5- Protein predictedi

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi601 – 6011ZincUniRule annotation
Metal bindingi603 – 6031ZincUniRule annotation
Metal bindingi609 – 6091ZincUniRule annotation
Active sitei717 – 7171UniRule annotation

GO - Molecular functioni

  1. histone deacetylase activity Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

HydrolaseSAAS annotation

Keywords - Ligandi

Metal-bindingUniRule annotation, ZincUniRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
AGAP000410-PAImported
Gene namesi
ORF Names:AgaP_AGAP000410Imported
OrganismiAnopheles gambiae (African malaria mosquito)Imported
Taxonomic identifieri7165 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraNematoceraCulicoideaCulicidaeAnophelinaeAnopheles
ProteomesiUP000007062: Chromosome X

Subcellular locationi

GO - Cellular componenti

  1. histone deacetylase complex Source: InterPro
Complete GO annotation...

Interactioni

Protein-protein interaction databases

STRINGi7165.AGAP000410-PA.

Structurei

3D structure databases

ProteinModelPortaliQ7QFC8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiCOG0123.
InParanoidiQ7QFC8.
KOiK11406.
OrthoDBiEOG7RFTH5.
PhylomeDBiQ7QFC8.

Family and domain databases

Gene3Di3.40.800.20. 1 hit.
InterProiIPR000286. His_deacetylse.
IPR023801. His_deacetylse_dom.
IPR017320. Histone_deAcase_II_euk.
[Graphical view]
PANTHERiPTHR10625. PTHR10625. 1 hit.
PfamiPF00850. Hist_deacetyl. 1 hit.
[Graphical view]
PIRSFiPIRSF037911. HDAC_II_euk. 1 hit.
PRINTSiPR01270. HDASUPER.

Sequencei

Sequence statusi: Complete.

Q7QFC8-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MEMARDSTMG RDRVLVVPNT GIALNSSSSS SQIAAPADIS QQILELQKEQ
60 70 80 90 100
ELEKQKLWHA FQEKNKELEM QHRQQLEHKF QELRDQRIAE EAAQQRERRE
110 120 130 140 150
REAIKRKEKH ECCANASSEV KQKLQTFLIQ KKQAAASNGL SSPLPYRNWG
160 170 180 190 200
VVKSSSGESL PGGAVAAAVS SHPYKIPPPP SSIAKYDPDF PLRKTASEPN
210 220 230 240 250
LLKIRLKQRV IEKRSLNGPL AARRQERLRR LQKQQHNQAL AQTNCAASAS
260 270 280 290 300
VATTDSGPNS PPTVGSRASP TNAPIQEENE DPQYGSVTSR ASINDLSLFS
310 320 330 340 350
SPSMPNISLG RPHLGSSAAA SVAHLALNAT RPTHLGVGAG IGGQAGSVPF
360 370 380 390 400
GSPMLDLSEQ QQRSQNVAAE RQAYEQHMLM KQKIRQTALT RAANCVNREP
410 420 430 440 450
QLREEVESNE VIDLTDKKQP PKTVLASSVI KSTSQSHLLS SSSHGVDGEP
460 470 480 490 500
PTAQQQQQQQ QQHLSELIHQ QQHYHREREL FMRRSIQLSV LEDPYSHHAG
510 520 530 540 550
SAGGSGGAAA AAAAAAAAAN LLRPLSRTSS SPLVHLSSIG GGGGGGKRFG
560 570 580 590 600
RRPSDGPSKA CSPTLGRGRA VTTICHRHRE QKLRPATTGL AFDSLMLKHV
610 620 630 640 650
CACGDNANHP EHSGRLQSIW ARLLGTGLAI RCDKLRSRKA TQEELQTVHT
660 670 680 690 700
EGHALLFGTS QLNRQKVDTS RVSFVRLAII PAAAARMAAG CVIDLSYKVA
710 720 730 740 750
RGENRNGFAV VRPPGHHAEA DAAMGFCFFN SIALAARLLR HRMPHEMRRI
760 770 780 790 800
LIVDWDVHHG NGTQQAFYDD ASVLYLSVHR HDDGNFFPGT GGPAECGVGT
810 820 830 840 850
GLGYNVNVAW SGGVNPPLGD AEYLAAFRTV VMPIARDFAP DIVLVSAGFD
860 870 880 890 900
AAVGHPAPLG GYVVSPACFG HLTRELMQLA NGKIVLALEG GYDLPAICDS
910 920 930 940 950
AEECVRALLG ESTSSIAPSE LARPPCQAAV ETLQKTIAIQ VSHWPCVKRL
960 970 980 990 1000
AHTVGLSALQ AHSSEREESD TVTAMAGLSM QPLKRTSDVS CEDSEEPMDQ

DESK
Length:1,004
Mass (Da):108,483
Last modified:July 27, 2011 - v5
Checksum:iA4E8ED41EE612317
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AAAB01008846 Genomic DNA. Translation: EAA06252.5.
RefSeqiXP_310688.5. XM_310688.5.

Genome annotation databases

EnsemblMetazoaiAGAP000410-RA; AGAP000410-PA; AGAP000410.
GeneIDi1271834.
KEGGiaga:AgaP_AGAP000410.
VectorBaseiAGAP000410. Anopheles gambiae.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AAAB01008846 Genomic DNA. Translation: EAA06252.5 .
RefSeqi XP_310688.5. XM_310688.5.

3D structure databases

ProteinModelPortali Q7QFC8.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 7165.AGAP000410-PA.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblMetazoai AGAP000410-RA ; AGAP000410-PA ; AGAP000410 .
GeneIDi 1271834.
KEGGi aga:AgaP_AGAP000410.
VectorBasei AGAP000410. Anopheles gambiae.

Phylogenomic databases

eggNOGi COG0123.
InParanoidi Q7QFC8.
KOi K11406.
OrthoDBi EOG7RFTH5.
PhylomeDBi Q7QFC8.

Family and domain databases

Gene3Di 3.40.800.20. 1 hit.
InterProi IPR000286. His_deacetylse.
IPR023801. His_deacetylse_dom.
IPR017320. Histone_deAcase_II_euk.
[Graphical view ]
PANTHERi PTHR10625. PTHR10625. 1 hit.
Pfami PF00850. Hist_deacetyl. 1 hit.
[Graphical view ]
PIRSFi PIRSF037911. HDAC_II_euk. 1 hit.
PRINTSi PR01270. HDASUPER.
ProtoNeti Search...

Publicationsi

  1. "The genome sequence of the malaria mosquito Anopheles gambiae."
    Holt R.A., Subramanian G.M., Halpern A., Sutton G.G., Charlab R., Nusskern D.R., Wincker P., Clark A.G., Ribeiro J.M., Wides R., Salzberg S.L., Loftus B., Yandell M., Majoros W.H., Rusch D.B., Lai Z., Kraft C.L., Abril J.F.
    , Anthouard V., Arensburger P., Atkinson P.W., Baden H., de Berardinis V., Baldwin D., Benes V., Biedler J., Blass C., Bolanos R., Boscus D., Barnstead M., Cai S., Center A., Chaturverdi K., Christophides G.K., Chrystal M.A., Clamp M., Cravchik A., Curwen V., Dana A., Delcher A., Dew I., Evans C.A., Flanigan M., Grundschober-Freimoser A., Friedli L., Gu Z., Guan P., Guigo R., Hillenmeyer M.E., Hladun S.L., Hogan J.R., Hong Y.S., Hoover J., Jaillon O., Ke Z., Kodira C., Kokoza E., Koutsos A., Letunic I., Levitsky A., Liang Y., Lin J.J., Lobo N.F., Lopez J.R., Malek J.A., McIntosh T.C., Meister S., Miller J., Mobarry C., Mongin E., Murphy S.D., O'Brochta D.A., Pfannkoch C., Qi R., Regier M.A., Remington K., Shao H., Sharakhova M.V., Sitter C.D., Shetty J., Smith T.J., Strong R., Sun J., Thomasova D., Ton L.Q., Topalis P., Tu Z., Unger M.F., Walenz B., Wang A., Wang J., Wang M., Wang X., Woodford K.J., Wortman J.R., Wu M., Yao A., Zdobnov E.M., Zhang H., Zhao Q., Zhao S., Zhu S.C., Zhimulev I., Coluzzi M., della Torre A., Roth C.W., Louis C., Kalush F., Mural R.J., Myers E.W., Adams M.D., Smith H.O., Broder S., Gardner M.J., Fraser C.M., Birney E., Bork P., Brey P.T., Venter J.C., Weissenbach J., Kafatos F.C., Collins F.H., Hoffman S.L.
    Science 298:129-149(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: PESTImported.

Entry informationi

Entry nameiQ7QFC8_ANOGA
AccessioniPrimary (citable) accession number: Q7QFC8
Entry historyi
Integrated into UniProtKB/TrEMBL: December 15, 2003
Last sequence update: July 27, 2011
Last modified: October 29, 2014
This is version 71 of the entry and version 5 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3