Q7QFA2 (Q7QFA2_ANOGA) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
AGAP000380-PA EMBL EAA06405.5

Gene names

ORF Names:

AgaP_AGAP000380 EMBL EAA06405.5

Organism

Anopheles gambiae (African malaria mosquito)

Taxonomic identifier

7165 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Endopterygota › Diptera › Nematocera › Culicoidea › Culicidae › Anophelinae › Anopheles

Protein attributes

Sequence length	656 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Cofactor	Binds 1 magnesium ion per subunit By similarity. PIRSR PIRSR017434-2
Caution	The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. EMBL EAA06405.5

Ontologies

Keywords
Ligand	Magnesium PIRSR PIRSR017434-2 Metal-binding PIRSR PIRSR017434-2
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Molecular function	metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Active site	86	1	Nucleophile By similarity PIRSR PIRSR017434-1
	Active site	88	1	Proton donor By similarity PIRSR PIRSR017434-1
	Metal binding	86	1	Magnesium By similarity PIRSR PIRSR017434-2
	Metal binding	88	1	Magnesium; via carbonyl oxygen By similarity PIRSR PIRSR017434-2
	Metal binding	387	1	Magnesium By similarity PIRSR PIRSR017434-2

Sequences

	Sequence		Length	Mass (Da)
	Q7QFA2 [UniParc]. Last modified July 27, 2011. Version 5. Checksum: F0534BEAD9C92A49	FASTA	656	74,022
	10 20 30 40 50 60 MPDISQDEFE AKLPHLAPAT AAELRQRANS GGSRAAARRP GAATNQPTAA DTAVAKPAYG 70 80 90 100 110 120 YKREISHRIF VNRSMHLENI KFYGFDMDYT IAEYKSPQYE QLGFDLVKER LVSLGYPAEI 130 140 150 160 170 180 RQFEYDPSFP VRGLWFDSLY GNLLKVDAYG NILVCVHGFE FLKHHQVYEL YPNKFLQLDE 190 200 210 220 230 240 SRVYVLNTLF NLPETYLFAC LVDFFTHSPQ YAEQVDRTGV KYGELFMSFK SIFQDVRGAV 250 260 270 280 290 300 DWVHIYGDLK KKTLENLDEY VKKDERLPMV LSRIRESGAK LFLLTNSDYM FTDRIMTFLF 310 320 330 340 350 360 DFPHGGKPDE PHRDWKTYFD TIVVDARKPL FFGEGTILRQ VDTSTGALKV GTHMGPLQAN 370 380 390 400 410 420 QVYSGGSCDV FTKLIGAKGK DVLYIGDHIF GDILKSKKIR GWRTFLIVPE LVQELHVWTD 430 440 450 460 470 480 KCQLFAQLQQ LDVRLGDLYK NLDSSAKEKP DIRSVRTAIR DVTHKMDLAY GMMGSLFRSG 490 500 510 520 530 540 SRQTFFAGQV VRYADLYAAT ILNLMYYPFS YMFRAPAMLL PHESTVAHEQ RFTLDAPMIQ 550 560 570 580 590 600 RTRPPRAELQ LSAAAAAPPP HELDDEEEGA EGDADARGDE SKEVGRLLLG TPQPSSLPSA 610 620 630 640 650 TGSELSVSVP HTRPETPRSV THTHDEDYSD EDSDDQKRTK GGEARGAGDG PASAQA

References

[1]

"The genome sequence of the malaria mosquito Anopheles gambiae." Holt R.A., Subramanian G.M., Halpern A., Sutton G.G., Charlab R., Nusskern D.R., Wincker P., Clark A.G., Ribeiro J.M.C., Wides R., Salzberg S.L., Loftus B.J., Yandell M.D., Majoros W.H., Rusch D.B., Lai Z., Kraft C.L., Abril J.F. , Anthouard V., Arensburger P., Atkinson P.W., Baden H., de Berardinis V., Baldwin D., Benes V., Biedler J., Blass C., Bolanos R., Boscus D., Barnstead M., Cai S., Center A., Chaturverdi K., Christophides G.K., Chrystal M.A.M., Clamp M., Cravchik A., Curwen V., Dana A., Delcher A., Dew I., Evans C.A., Flanigan M., Grundschober-Freimoser A., Friedli L., Gu Z., Guan P., Guigo R., Hillenmeyer M.E., Hladun S.L., Hogan J.R., Hong Y.S., Hoover J., Jaillon O., Ke Z., Kodira C.D., Kokoza E., Koutsos A., Letunic I., Levitsky A.A., Liang Y., Lin J.-J., Lobo N.F., Lopez J.R., Malek J.A., McIntosh T.C., Meister S., Miller J.R., Mobarry C., Mongin E., Murphy S.D., O'Brochta D.A., Pfannkoch C., Qi R., Regier M.A., Remington K., Shao H., Sharakhova M.V., Sitter C.D., Shetty J., Smith T.J., Strong R., Sun J., Thomasova D., Ton L.Q., Topalis P., Tu Z.J., Unger M.F., Walenz B., Wang A.H., Wang J., Wang M., Wang X., Woodford K.J., Wortman J.R., Wu M., Yao A., Zdobnov E.M., Zhang H., Zhao Q., Zhao S., Zhu S.C., Zhimulev I., Coluzzi M., della Torre A., Roth C.W., Louis C., Kalush F., Mural R.J., Myers E.W., Adams M.D., Smith H.O., Broder S., Gardner M.J., Fraser C.M., Birney E., Bork P., Brey P.T., Venter J.C., Weissenbach J., Kafatos F.C., Collins F.H., Hoffman S.L. Science 298:129-149(2002) [PubMed: 12364791] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: PEST.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AAAB01008846 Genomic DNA. Translation: EAA06405.5.
RefSeq	XP_310728.5. XM_310728.5.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1271873.
KEGG	aga:AgaP_AGAP000380.
Phylogenomic databases
OMA	EEEYMAL.
PhylomeDB	Q7QFA2.
Family and domain databases
InterPro	IPR023214. HAD-like_dom. IPR008380. HAD-SF_hydro_IG_5-nucl. IPR016695. Pur_nucleotidase. [Graphical view]
KO	K01081.
PANTHER	PTHR12103. HAD-SF_hydro_IG_5-nucl. 1 hit.
Pfam	PF05761. 5_nucleotid. 1 hit. [Graphical view]
PIRSF	PIRSF017434. Purine_5'-nucleotidase. 1 hit.
SUPFAM	SSF56784. HAD-like_dom. 1 hit.
TIGRFAMs	TIGR02244. HAD-IG-Ncltidse. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Q7QFA2_ANOGA

Accession

Primary (citable) accession number: Q7QFA2

Entry history

Integrated into UniProtKB/TrEMBL:	December 15, 2003
Last sequence update:	July 27, 2011
Last modified:	January 25, 2012
This is version 47 of the entry and version 5 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)