Q7QEK5 (Q7QEK5_ANOGA) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
AGAP000032-PA EMBL EAA06518.5

Gene names

ORF Names:

AgaP_AGAP000032 EMBL EAA06518.5

Organism

Anopheles gambiae (African malaria mosquito) [Reference proteome]

Taxonomic identifier

7165 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Protostomia › Ecdysozoa › Panarthropoda › Arthropoda › Mandibulata › Pancrustacea › Hexapoda › Insecta › Dicondylia › Pterygota › Neoptera › Endopterygota › Diptera › Nematocera › Culicimorpha › Culicoidea › Culicidae › Anophelinae › Anopheles › Cellia › Pyretophorus › gambiae species complex

Protein attributes

Sequence length	1540 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Subcellular location	Membrane; Single-pass type I membrane protein By similarity RuleBase RU003762.
Sequence similarities	Belongs to the integrin alpha chain family. RuleBase RU003762
Caution	The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. EMBL EAA06518.5

Ontologies

Keywords
Biological process	Cell adhesion RuleBase RU003762 SAAS SAAS013519
Cellular component	Membrane
Domain	Transmembrane Transmembrane helix SAAS SAAS013519
Molecular function	Integrin RuleBase RU003762 SAAS SAAS013519 Receptor RuleBase RU003762 SAAS SAAS013519
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	cell adhesion Inferred from electronic annotation. Source: UniProtKB-KW integrin-mediated signaling pathway Inferred from electronic annotation. Source: UniProtKB-KW
Cellular_component	integrin complex Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q7QEK5 [UniParc]. Last modified July 27, 2011. Version 5. Checksum: 63016C99CF3FF456	FASTA	1,540	166,687
	10 20 30 40 50 60 MRNPFTVRDG GRAHVPRTAA TLMQLIATAL LLVWLGQAAT AFNLDTINFI LKEGDPSSMF 70 80 90 100 110 120 GFSVALHREQ NNSWVIVGAP TANTSQPGVI KGGAVYRCDI YDDYRCYLLP FDTKGNTYND 130 140 150 160 170 180 QNEQIDTKSN QWFGATVASA GIDGPLVACA PRYVFHQLQP RKAERVEPVG TCYLAKNNMQ 190 200 210 220 230 240 NFEDISPCRT AYWGYHRQGS CQAGFSAAIT NDGSRLFIGA PGSYYWQGQM YSINTDVVFP 250 260 270 280 290 300 YKPPRYGHFG EGGQIYSFSL NNPKDKVYKT LEDTKKEDDS YLGYSSTTGD FNGDGTQGVA 310 320 330 340 350 360 VGKPRGARLL GKVLIYSWNM TNQQNITGEQ IGAYFGYSLA AVDVDGDKLD DLIIGAPMYT 370 380 390 400 410 420 EPNNEGKYET GRVYIMYQGA AADGRFRELD TRDGVNSKAR FGLAVCSLAD LNLDGYGDFA 430 440 450 460 470 480 VGAPYDGPNG RGAVYIFYGS RTGPLAKASQ VIQAEDMAGV TRLSTFGFSL SGGIDLDGNQ 490 500 510 520 530 540 YPDMVVGAYE SDKALVFKAR PVAAMVASTL FEPKSKLIAL DVKNCALKRT NKTVPCTVVN 550 560 570 580 590 600 SCLKYNGINV PPMLDIEISW TLDARKARNP RMFFLDHEGN HTRTQLMRLA RGKLECIEDK 610 620 630 640 650 660 VYVADNIRDK ITPLEVEMAY GLRQNVLGRQ RRPRAHTEPV LDQNRGTVQR DAINIQKNCG 670 680 690 700 710 720 PDNVCVPDLR MEVKSVDDYL LGSNNLLSVE VLITNRGEDA FEAGFYMAVP NGLDFRRVDR 730 740 750 760 770 780 LGEVKDVPVL CTAPSAATNK TLKCDIGNPL SSGKVVHFKV ILAPSFSAGM GSSYDFYLET 790 800 810 820 830 840 NSTNAELDGN RQDNVMRKTI GILVQTDLAM SGVSLPDQFH YNHSEYKSLA EAKTERDIGP 850 860 870 880 890 900 QVVHIYEIRN EGPSTIDEAE FFVLWPYETV DGVPLMYLLN QPETHGNIEC LPTEYANPLN 910 920 930 940 950 960 LAIDSALARK SFLDKVGVSS ASYSSSMGRT AKFNSAAGSG TVGAEGASSI SFHSTTGSSS 970 980 990 1000 1010 1020 AGRGVGGSSS SSAAGSSSSG SRTSSSSSSS SSSSSSSSSF SSSSGSGSSG SSGAGVSESR 1030 1040 1050 1060 1070 1080 YSSNVRGSTA AGAEGANYNR VSGGGSERRY QTESSDTSAS GRMRGEYGQM QGEAYSRQGY 1090 1100 1110 1120 1130 1140 AQQGSHGEGY RQQQQHYDGG VRVDAGGYGA AGGAGGSGFG GGSSSSSSSR NSTSSVVYYT 1150 1160 1170 1180 1190 1200 SKNRTTYRDE DGRVHVSESS EYHRHDSDLG GGQALGGGTS SSAATGSSTR RRMMSQQDGE 1210 1220 1230 1240 1250 1260 APPRTGLITE FMHLGDYTGS GGAAGSAASL NDLNRLENKF RTEYSQQQQQ QQQQVGGGSS 1270 1280 1290 1300 1310 1320 TAYHGASSSG SSSSGRQSST HYTSSREQHH VESATFASNA YHGVANDLEQ DEHEEDDYDS 1330 1340 1350 1360 1370 1380 YDRSEELDSY ADPDLAAGHR RTYPPGYGLP HLKHQHLNQG HENVEQKFRY YQRFDRQRRQ 1390 1400 1410 1420 1430 1440 APGHRDEADR ALEEALRCHA TRCAIIHCKA GPIGNSDVAF VALRTRAVAH TLHQLSSSAP 1450 1460 1470 1480 1490 1500 LHFSTMNVAR VLKLPYIGEP KDKPIKTHEI KVLAEPEPTI KPEVVPLWIV VLAACAGALI 1510 1520 1530 1540 LLLIIYGLAK SGFFERKRPT DASERQPLNR NGNYHGDEHL

References

[1]

"The genome sequence of the malaria mosquito Anopheles gambiae." Holt R.A., Subramanian G.M., Halpern A., Sutton G.G., Charlab R., Nusskern D.R., Wincker P., Clark A.G., Ribeiro J.M.C., Wides R., Salzberg S.L., Loftus B.J., Yandell M.D., Majoros W.H., Rusch D.B., Lai Z., Kraft C.L., Abril J.F. , Anthouard V., Arensburger P., Atkinson P.W., Baden H., de Berardinis V., Baldwin D., Benes V., Biedler J., Blass C., Bolanos R., Boscus D., Barnstead M., Cai S., Center A., Chaturverdi K., Christophides G.K., Chrystal M.A.M., Clamp M., Cravchik A., Curwen V., Dana A., Delcher A., Dew I., Evans C.A., Flanigan M., Grundschober-Freimoser A., Friedli L., Gu Z., Guan P., Guigo R., Hillenmeyer M.E., Hladun S.L., Hogan J.R., Hong Y.S., Hoover J., Jaillon O., Ke Z., Kodira C.D., Kokoza E., Koutsos A., Letunic I., Levitsky A.A., Liang Y., Lin J.-J., Lobo N.F., Lopez J.R., Malek J.A., McIntosh T.C., Meister S., Miller J.R., Mobarry C., Mongin E., Murphy S.D., O'Brochta D.A., Pfannkoch C., Qi R., Regier M.A., Remington K., Shao H., Sharakhova M.V., Sitter C.D., Shetty J., Smith T.J., Strong R., Sun J., Thomasova D., Ton L.Q., Topalis P., Tu Z.J., Unger M.F., Walenz B., Wang A.H., Wang J., Wang M., Wang X., Woodford K.J., Wortman J.R., Wu M., Yao A., Zdobnov E.M., Zhang H., Zhao Q., Zhao S., Zhu S.C., Zhimulev I., Coluzzi M., della Torre A., Roth C.W., Louis C., Kalush F., Mural R.J., Myers E.W., Adams M.D., Smith H.O., Broder S., Gardner M.J., Fraser C.M., Birney E., Bork P., Brey P.T., Venter J.C., Weissenbach J., Kafatos F.C., Collins F.H., Hoffman S.L. Science 298:129-149(2002) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: PEST EMBL EAA06518.5.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AAAB01008846 Genomic DNA. Translation: EAA06518.5.
RefSeq	XP_311131.5. XM_311131.5.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	7165.AGAP000032-PA. Q7QEK5.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblMetazoa	AGAP000032-RA; AGAP000032-PA; AGAP000032.
GeneID	1272247.
KEGG	aga:AgaP_AGAP000032.
VectorBase	AGAP000032. Anopheles gambiae.
Phylogenomic databases
eggNOG	NOG26407.
OrthoDB	EOG4WWQ0D.
PhylomeDB	Q7QEK5.
Family and domain databases
InterPro	IPR013517. FG-GAP. IPR013519. Int_alpha_beta-p. IPR000413. Integrin_alpha. IPR013649. Integrin_alpha-2. [Graphical view]
Pfam	PF01839. FG-GAP. 1 hit. PF08441. Integrin_alpha2. 1 hit. [Graphical view]
PRINTS	PR01185. INTEGRINA.
SMART	SM00191. Int_alpha. 6 hits. [Graphical view]
PROSITE	PS51470. FG_GAP. 7 hits. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q7QEK5_ANOGA

Accession

Primary (citable) accession number: Q7QEK5

Entry history

Integrated into UniProtKB/TrEMBL:	December 15, 2003
Last sequence update:	July 27, 2011
Last modified:	May 1, 2013
This is version 74 of the entry and version 5 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)