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Protein

Superoxide dismutase [Cu-Zn]

Gene

CUSOD3

Organism
Anopheles gambiae (African malaria mosquito)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Destroys radicals which are normally produced within the cells and which are toxic to biological systems.UniRule annotation

Catalytic activityi

2 superoxide + 2 H+ = O2 + H2O2.UniRule annotation

Cofactori

Protein has several cofactor binding sites:
  • Cu cationUniRule annotationNote: Binds 1 copper ion per subunit.UniRule annotation
  • Zn2+UniRule annotationNote: Binds 1 zinc ion per subunit.UniRule annotation

GO - Molecular functioni

Keywordsi

Molecular functionOxidoreductaseUniRule annotation
LigandCopperUniRule annotation, Metal-bindingUniRule annotation, ZincUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Superoxide dismutase [Cu-Zn]UniRule annotation (EC:1.15.1.1UniRule annotation)
Gene namesi
Name:CUSOD3Imported
Synonyms:1272692Imported
ORF Names:AgaP_AGAP010347Imported
OrganismiAnopheles gambiae (African malaria mosquito)Imported
Taxonomic identifieri7165 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraNematoceraCulicoideaCulicidaeAnophelinaeAnopheles
Proteomesi
  • UP000007062 Componenti: Chromosome 3L

Structurei

3D structure databases

ProteinModelPortaliQ7QDP9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini10 – 148Sod_CuInterPro annotationAdd BLAST139

Sequence similaritiesi

Belongs to the Cu-Zn superoxide dismutase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000263447.
OMAiIHTFGDN.
OrthoDBiEOG091G06EP.

Family and domain databases

CDDicd00305. Cu-Zn_Superoxide_Dismutase. 1 hit.
Gene3Di2.60.40.200. 1 hit.
InterProiView protein in InterPro
IPR036423. SOD-like_Cu/Zn_dom_sf.
IPR024134. SOD_Cu/Zn_/chaperone.
IPR018152. SOD_Cu/Zn_BS.
IPR001424. SOD_Cu_Zn_dom.
PANTHERiPTHR10003. PTHR10003. 1 hit.
PfamiView protein in Pfam
PF00080. Sod_Cu. 1 hit.
PRINTSiPR00068. CUZNDISMTASE.
SUPFAMiSSF49329. SSF49329. 1 hit.
PROSITEiView protein in PROSITE
PS00087. SOD_CU_ZN_1. 1 hit.
PS00332. SOD_CU_ZN_2. 1 hit.

Sequencei

Sequence statusi: Complete.

Q7QDP9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPLKAVCVLN GEVKGTIFFE QSGESDPVKV TGSVTGLKPG DHGFHIHEFG
60 70 80 90 100
DNTNGCMSTG AHFNPYAKTH GGPDAEERHA GDMGNIVADE NGEAKVDLTA
110 120 130 140 150
TQIALSGALN VVGRSLVVHA DPDDLGVGGH ELSKTTGNAG ARLACGVIGL

CKI
Length:153
Mass (Da):15,676
Last modified:December 7, 2004 - v2
Checksum:iA034C01A8D9C95ED
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAAB01008849 Genomic DNA. Translation: EAA07169.2.
RefSeqiXP_311594.2. XM_311594.2.

Genome annotation databases

EnsemblMetazoaiAGAP010347-RA; AGAP010347-PA; AGAP010347.
GeneIDi1272692.
VectorBaseiAGAP010347-RA; AGAP010347-PA; AGAP010347.

Similar proteinsi

Entry informationi

Entry nameiQ7QDP9_ANOGA
AccessioniPrimary (citable) accession number: Q7QDP9
Entry historyiIntegrated into UniProtKB/TrEMBL: December 15, 2003
Last sequence update: December 7, 2004
Last modified: October 25, 2017
This is version 108 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported