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Protein

Alpha-amylase

Gene

AgaP_AGAP002318

Organism
Anopheles gambiae (African malaria mosquito)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

Endohydrolysis of (1->4)-alpha-D-glucosidic linkages in polysaccharides containing three or more (1->4)-alpha-linked D-glucose units.UniRule annotationSAAS annotation

GO - Molecular functioni

  1. alpha-amylase activity Source: UniProtKB-EC
  2. cation binding Source: InterPro

GO - Biological processi

  1. carbohydrate metabolic process Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

GlycosidaseUniRule annotation, Hydrolase

Keywords - Biological processi

Carbohydrate metabolismUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Alpha-amylaseUniRule annotationSAAS annotation (EC:3.2.1.1UniRule annotationSAAS annotation)
Gene namesi
ORF Names:AgaP_AGAP002318Imported
OrganismiAnopheles gambiae (African malaria mosquito)Imported
Taxonomic identifieri7165 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraNematoceraCulicoideaCulicidaeAnophelinaeAnopheles
ProteomesiUP000007062 Componenti: Chromosome 2R

Interactioni

Protein-protein interaction databases

STRINGi7165.AGAP002318-PA.

Family & Domainsi

Sequence similaritiesi

Belongs to the glycosyl hydrolase 13 family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0366.
HOGENOMiHOG000253313.
InParanoidiQ7QBU5.
KOiK01176.
OrthoDBiEOG7RJPR2.
PhylomeDBiQ7QBU5.

Family and domain databases

Gene3Di2.60.40.1180. 1 hit.
3.20.20.80. 1 hit.
InterProiIPR006048. A-amylase_b_C.
IPR006046. Alpha_amylase.
IPR015902. Glyco_hydro_13.
IPR013780. Glyco_hydro_13_b.
IPR006047. Glyco_hydro_13_cat_dom.
IPR006589. Glyco_hydro_13_sub_cat_dom.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PANTHERiPTHR10357. PTHR10357. 1 hit.
PfamiPF00128. Alpha-amylase. 1 hit.
PF02806. Alpha-amylase_C. 1 hit.
[Graphical view]
PRINTSiPR00110. ALPHAAMYLASE.
SMARTiSM00642. Aamy. 1 hit.
SM00632. Aamy_C. 1 hit.
[Graphical view]
SUPFAMiSSF51445. SSF51445. 1 hit.

Sequencei

Sequence statusi: Complete.

Q7QBU5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRAAVVLLAA CATLAAAQFN THQWADRSGI VHLFEWKWDD IAAECENFLA
60 70 80 90 100
PRGYAGVQVS PPTENAVIGG NFRRPWWERY QPMSYRLETR SGSEAQFASM
110 120 130 140 150
VRRCNDVGVR IYVDLVINHM ADLVGGGGTA GSTANRPNFS FPGVPFSVTD
160 170 180 190 200
FNPPCIITNY NDPIMVRNCQ LVSLPDLNQG VPWVRDKIVE LMNHLIGLGV
210 220 230 240 250
AGFRVDAVKH MWPGDLQAIY SRMNNLPTSH GFPPNARPFL TQEVIDLGGE
260 270 280 290 300
AVTRDEYTHL GTITEFRHSA EIGRVFRGRN PFRHLTNWGT GWGFLPSHLA
310 320 330 340 350
LVFIDNHDNQ RGHGGGGSDV LTYKVPRNYK MATAFMLAHP FGIVRVMSSF
360 370 380 390 400
SFSDSEQGPP QDANGNLLSP TFNPDNSCGP GWVCEHRWRQ IYNMIGFRNA
410 420 430 440 450
VAGTQINDWW DNGNYQMAFC RGARGFIAFN LESFDLNQSL QTCLPAGTYC
460 470 480 490
DVISGDLVNG ACTGNTITVG GDGRAQIVLP ANAYDGVLAI HINSRV
Length:496
Mass (Da):54,746
Last modified:July 27, 2011 - v5
Checksum:i965ADE9C71C71FA1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAAB01008859 Genomic DNA. Translation: EAA07514.5.
RefSeqiXP_312654.5. XM_312654.5.

Genome annotation databases

EnsemblMetazoaiAGAP002318-RA; AGAP002318-PA; AGAP002318.
GeneIDi1273652.
KEGGiaga:AgaP_AGAP002318.
VectorBaseiAGAP002318. Anopheles gambiae.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAAB01008859 Genomic DNA. Translation: EAA07514.5.
RefSeqiXP_312654.5. XM_312654.5.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi7165.AGAP002318-PA.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiAGAP002318-RA; AGAP002318-PA; AGAP002318.
GeneIDi1273652.
KEGGiaga:AgaP_AGAP002318.
VectorBaseiAGAP002318. Anopheles gambiae.

Phylogenomic databases

eggNOGiCOG0366.
HOGENOMiHOG000253313.
InParanoidiQ7QBU5.
KOiK01176.
OrthoDBiEOG7RJPR2.
PhylomeDBiQ7QBU5.

Family and domain databases

Gene3Di2.60.40.1180. 1 hit.
3.20.20.80. 1 hit.
InterProiIPR006048. A-amylase_b_C.
IPR006046. Alpha_amylase.
IPR015902. Glyco_hydro_13.
IPR013780. Glyco_hydro_13_b.
IPR006047. Glyco_hydro_13_cat_dom.
IPR006589. Glyco_hydro_13_sub_cat_dom.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PANTHERiPTHR10357. PTHR10357. 1 hit.
PfamiPF00128. Alpha-amylase. 1 hit.
PF02806. Alpha-amylase_C. 1 hit.
[Graphical view]
PRINTSiPR00110. ALPHAAMYLASE.
SMARTiSM00642. Aamy. 1 hit.
SM00632. Aamy_C. 1 hit.
[Graphical view]
SUPFAMiSSF51445. SSF51445. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "The genome sequence of the malaria mosquito Anopheles gambiae."
    Holt R.A., Subramanian G.M., Halpern A., Sutton G.G., Charlab R., Nusskern D.R., Wincker P., Clark A.G., Ribeiro J.M., Wides R., Salzberg S.L., Loftus B., Yandell M., Majoros W.H., Rusch D.B., Lai Z., Kraft C.L., Abril J.F.
    , Anthouard V., Arensburger P., Atkinson P.W., Baden H., de Berardinis V., Baldwin D., Benes V., Biedler J., Blass C., Bolanos R., Boscus D., Barnstead M., Cai S., Center A., Chaturverdi K., Christophides G.K., Chrystal M.A., Clamp M., Cravchik A., Curwen V., Dana A., Delcher A., Dew I., Evans C.A., Flanigan M., Grundschober-Freimoser A., Friedli L., Gu Z., Guan P., Guigo R., Hillenmeyer M.E., Hladun S.L., Hogan J.R., Hong Y.S., Hoover J., Jaillon O., Ke Z., Kodira C., Kokoza E., Koutsos A., Letunic I., Levitsky A., Liang Y., Lin J.J., Lobo N.F., Lopez J.R., Malek J.A., McIntosh T.C., Meister S., Miller J., Mobarry C., Mongin E., Murphy S.D., O'Brochta D.A., Pfannkoch C., Qi R., Regier M.A., Remington K., Shao H., Sharakhova M.V., Sitter C.D., Shetty J., Smith T.J., Strong R., Sun J., Thomasova D., Ton L.Q., Topalis P., Tu Z., Unger M.F., Walenz B., Wang A., Wang J., Wang M., Wang X., Woodford K.J., Wortman J.R., Wu M., Yao A., Zdobnov E.M., Zhang H., Zhao Q., Zhao S., Zhu S.C., Zhimulev I., Coluzzi M., della Torre A., Roth C.W., Louis C., Kalush F., Mural R.J., Myers E.W., Adams M.D., Smith H.O., Broder S., Gardner M.J., Fraser C.M., Birney E., Bork P., Brey P.T., Venter J.C., Weissenbach J., Kafatos F.C., Collins F.H., Hoffman S.L.
    Science 298:129-149(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: PESTImported.

Entry informationi

Entry nameiQ7QBU5_ANOGA
AccessioniPrimary (citable) accession number: Q7QBU5
Entry historyi
Integrated into UniProtKB/TrEMBL: December 15, 2003
Last sequence update: July 27, 2011
Last modified: April 1, 2015
This is version 92 of the entry and version 5 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.