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Q7QAH2 (Q7QAH2_ANOGA) Unreviewed, UniProtKB/TrEMBL

Last modified January 25, 2012. Version 70. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Methionine aminopeptidase RuleBase RU003653
EC=3.4.11.18 RuleBase RU003653
Gene names
ORF Names:AgaP_AGAP003700 EMBL EAA08766.5
OrganismAnopheles gambiae (African malaria mosquito)
Taxonomic identifier7165 [NCBI]
Taxonomic lineageEukaryota › Metazoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Endopterygota › Diptera › Nematocera › Culicoidea › Culicidae › Anophelinae › Anopheles

Protein attributes

Sequence length374 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Removes the N-terminal methionine from nascent proteins By similarity. RuleBase RU003653

Catalytic activity

Release of N-terminal amino acids, preferentially methionine, from peptides and arylamides. RuleBase RU003653

Cofactor

Binds 2 cobalt ions per subunit By similarity. RuleBase RU003653

Sequence similarities

Belongs to the peptidase M24A family. RuleBase RU003653

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. EMBL EAA08766.5

Sequences

Sequence LengthMass (Da)Tools
Q7QAH2 [UniParc].

Last modified July 27, 2011. Version 5.
Checksum: D890D1DE90BA445F

FASTA37442,353
        10         20         30         40         50         60 
MSDMAKHLCV TDDCKKPSTL QCPVCLKMGI QGSYFCSQDC FKGSWKEHKV IHLLAKGKET 

        70         80         90        100        110        120 
NAYNPWPYYT FTGKLRPFEQ TPRRPVPPHI PRPDYADHKE GRSKSEEALR GNNTIKVLDD 

       130        140        150        160        170        180 
EEIEGMRVAC RLGREVLDEA ARVCDVGVTT DEIDRAVHEA CIERECYPSP MNYYNFPKSC 

       190        200        210        220        230        240 
CTSVNEVICH GIPDLRPLED GDLCNVDVTV YHRGFHGDLN ETFFVGNVKE QHKKLVQVTY 

       250        260        270        280        290        300 
EALMKAIAIV KPGERYREIG NVIQKHVHAH GFSVVKSYCG HGIHRLFHTA PNVPHYAKNS 

       310        320        330        340        350        360 
AVGVMKPGHC FTIEPMISEG TWRDVSWPDD WTAVTADGLF SAQFEQTLLV TESGCDILTK 

       370 
RRNENGTPHF MDHM

« Hide

References

[1]"The genome sequence of the malaria mosquito Anopheles gambiae."
Holt R.A., Subramanian G.M., Halpern A., Sutton G.G., Charlab R., Nusskern D.R., Wincker P., Clark A.G., Ribeiro J.M.C., Wides R., Salzberg S.L., Loftus B.J., Yandell M.D., Majoros W.H., Rusch D.B., Lai Z., Kraft C.L., Abril J.F. expand/collapse author list , Anthouard V., Arensburger P., Atkinson P.W., Baden H., de Berardinis V., Baldwin D., Benes V., Biedler J., Blass C., Bolanos R., Boscus D., Barnstead M., Cai S., Center A., Chaturverdi K., Christophides G.K., Chrystal M.A.M., Clamp M., Cravchik A., Curwen V., Dana A., Delcher A., Dew I., Evans C.A., Flanigan M., Grundschober-Freimoser A., Friedli L., Gu Z., Guan P., Guigo R., Hillenmeyer M.E., Hladun S.L., Hogan J.R., Hong Y.S., Hoover J., Jaillon O., Ke Z., Kodira C.D., Kokoza E., Koutsos A., Letunic I., Levitsky A.A., Liang Y., Lin J.-J., Lobo N.F., Lopez J.R., Malek J.A., McIntosh T.C., Meister S., Miller J.R., Mobarry C., Mongin E., Murphy S.D., O'Brochta D.A., Pfannkoch C., Qi R., Regier M.A., Remington K., Shao H., Sharakhova M.V., Sitter C.D., Shetty J., Smith T.J., Strong R., Sun J., Thomasova D., Ton L.Q., Topalis P., Tu Z.J., Unger M.F., Walenz B., Wang A.H., Wang J., Wang M., Wang X., Woodford K.J., Wortman J.R., Wu M., Yao A., Zdobnov E.M., Zhang H., Zhao Q., Zhao S., Zhu S.C., Zhimulev I., Coluzzi M., della Torre A., Roth C.W., Louis C., Kalush F., Mural R.J., Myers E.W., Adams M.D., Smith H.O., Broder S., Gardner M.J., Fraser C.M., Birney E., Bork P., Brey P.T., Venter J.C., Weissenbach J., Kafatos F.C., Collins F.H., Hoffman S.L.
Science 298:129-149(2002) [PubMed: 12364791] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: PEST.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AAAB01008888 Genomic DNA. Translation: EAA08766.5.
RefSeqXP_313492.5. XM_313492.5.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRINGQ7QAH2.

Protein family/group databases

MEROPSM24.001.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID1274376.
KEGGaga:AgaP_AGAP003700.

Phylogenomic databases

OMAIEPMISE.
PhylomeDBQ7QAH2.

Family and domain databases

InterProIPR001714. Pept_M24_MAP.
IPR000994. Pept_M24_structural-domain.
IPR002467. Pept_M24A_MAP1.
[Graphical view]
Gene3DG3DSA:3.90.230.10. Peptidase_M24_cat_core. 1 hit.
KOK01265.
PfamPF00557. Peptidase_M24. 1 hit.
[Graphical view]
PRINTSPR00599. MAPEPTIDASE.
SUPFAMSSF55920. Peptidase_M24_cat_core. 1 hit.
TIGRFAMsTIGR00500. Met_pdase_I. 1 hit.
PROSITEPS00680. MAP_1. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ7QAH2_ANOGA
AccessionPrimary (citable) accession number: Q7QAH2
Entry history
Integrated into UniProtKB/TrEMBL: December 15, 2003
Last sequence update: July 27, 2011
Last modified: January 25, 2012
This is version 70 of the entry and version 5 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry info