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Q7Q504

- Q7Q504_ANOGA

UniProt

Q7Q504 - Q7Q504_ANOGA

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Protein
Submitted name: AGAP004656-PA
Gene
AgaP_AGAP004656
Organism
Anopheles gambiae (African malaria mosquito)
Status
Unreviewed - Annotation score: 1 out of 5 - Protein predictedi

Functioni

Catalytic activityi

S-adenosyl-L-methionine + L-lysine-[histone] = S-adenosyl-L-homocysteine + N(6)-methyl-L-lysine-[histone].SAAS annotations

GO - Molecular functioni

  1. histone-lysine N-methyltransferase activity Source: InterPro
  2. zinc ion binding Source: InterPro
Complete GO annotation...

GO - Biological processi

    Complete GO annotation...

    Keywords - Molecular functioni

    MethyltransferaseUniRule annotationSAAS annotations, Transferase

    Keywords - Ligandi

    Metal-binding, S-adenosyl-L-methionineSAAS annotations, Zinc

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    AGAP004656-PAImported
    Gene namesi
    ORF Names:AgaP_AGAP004656Imported
    OrganismiAnopheles gambiae (African malaria mosquito)
    Taxonomic identifieri7165 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraNematoceraCulicoideaCulicidaeAnophelinaeAnopheles
    ProteomesiUP000007062: Chromosome 2R

    Subcellular locationi

    GO - Cellular componenti

    1. nucleus Source: UniProtKB-KW
    Complete GO annotation...

    Keywords - Cellular componenti

    NucleusSAAS annotations

    Interactioni

    Protein-protein interaction databases

    STRINGi7165.AGAP004656-PA.

    Family & Domainsi

    Sequence similaritiesi

    Contains 1 post-SET domain.UniRule annotation
    Contains SET domain.SAAS annotations
    Contains post-SET domain.SAAS annotations

    Keywords - Domaini

    Zinc-fingerSAAS annotations

    Phylogenomic databases

    eggNOGiCOG2940.
    HOGENOMiHOG000046762.
    KOiK11424.
    OrthoDBiEOG7B05CD.
    PhylomeDBiQ7Q504.

    Family and domain databases

    Gene3Di3.30.40.10. 1 hit.
    InterProiIPR006560. AWS.
    IPR003616. Post-SET_dom.
    IPR000313. PWWP_dom.
    IPR001214. SET_dom.
    IPR011011. Znf_FYVE_PHD.
    IPR001965. Znf_PHD.
    IPR013083. Znf_RING/FYVE/PHD.
    [Graphical view]
    PfamiPF00855. PWWP. 2 hits.
    PF00856. SET. 1 hit.
    [Graphical view]
    SMARTiSM00570. AWS. 1 hit.
    SM00249. PHD. 4 hits.
    SM00508. PostSET. 1 hit.
    SM00317. SET. 1 hit.
    [Graphical view]
    SUPFAMiSSF57903. SSF57903. 1 hit.
    PROSITEiPS51215. AWS. 1 hit.
    PS50868. POST_SET. 1 hit.
    PS50812. PWWP. 2 hits.
    PS50280. SET. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q7Q504-1 [UniParc]FASTAAdd to Basket

    « Hide

    MFFAATAAAT NFETDLLSPT TTQKRVKSQE STPQSQKIAK QEPMSGSEMN     50
    ESGKENAFSD QIRNHPTDEN SNTVVRVPGR YLLKQLSSSL SPKMTEINID 100
    TDRRVSRYGR HQKQKDNSDY VPVDLMKYVG STPSKFKTKS ETDDPNSVNK 150
    TLETKPHSSD ELRTGSNDIS LSLTVVPLPL IDGSIMKRPE EKQLLSMEEI 200
    KIVGMEEPYY TDKGSDNNCF MNNLLERKTS SDADSGKGSS VDLAIIYRAG 250
    NLYWAAQTRK SIHWPCIVHV DPETDQITRL YGDKFLEVHV SYFGDRGRRA 300
    WIKEHSILPF EGVDEYCTNA KNMEYGKLLK SALKSERWKN ACSIAERYMT 350
    LALSERIASF DHEVKLELAR HKVMRHRMAI EGRIKNGASQ KMPALLPSDN 400
    SEVLEHWNKR DRSSSPESPE YELLPGVFPT KNNPIKKIKF SPSMQNCILN 450
    DNRSPLDRPL HSMDSEENPP GSATKANGPK AKTLGVSDLE NLNSTEYDDI 500
    LTFIRYYMFD GHTSYEVEKG LQLYVRGICN LKKHSNRGTE RTVGRQRMHA 550
    LRKSYEILGI EPSAEVSTSL KTRNAHPVIK KEPKTLEEKF IFELDKNFLM 600
    KGVPKGFVCY ICNRPNNVTK CSKCTLHLHL VCLANDPEEV VKMQELVDQK 650
    KLCCEKCSTT SIVEKTCFIC NDEIPEKSNE QIYRCVVGKC TQAYHISCLQ 700
    LFPQVRQVSA STIICPYHTC HTCVASEPRS TASMVKTTLA HCLKCPTSYH 750
    PSGNCIPAGS VLLTTTQLIC PKHTLEQIPL NVNWCFICGK GGNLICCETC 800
    PLACHPVCLQ FTPPDEKYFC EGCESGRLPL YNEIVIAKMG SFRWWPALTL 850
    PPSEIPQNML QLRHKPSDIC VKFFNTHDMS WLNRKRMYLY QREDSESLDG 900
    SQSGSSMDKR YRSAMTEASK IFKILQTRKM LGPSASLSYS KAVPVYKKIK 950
    TNRYIPPLKP PSVNRQLDGV EDSVCRCQPS DDDPCGPTSA CLNRAIMMEC 1000
    SSKTCPAKES CSNQRFTKRI YPALEVRFFS DKGFGLVALE DLKSGQFVIE 1050
    YVGEVINSEE FDRRVMMMQA AKETNYYFLT VEPDLTIDAG PKGNVSRFIN 1100
    HSCEPNCETQ KWTIGETRVI GLFAIKDINA GEELTFNYNL ESLGNNKRVC 1150
    LCGAGKCSGF IGEKYRPPNK KDIVISMKSE RSLKNGKKRV KIRRTKTTLT 1200
    QKTTTNLSET KDTNNQLNDN DVVMISAQEA VIVDLVDENA SAYPLASVHI 1250
    KQEKNDYNI 1259
    Length:1,259
    Mass (Da):142,173
    Last modified:July 27, 2011 - v5
    Checksum:iAAEEBE4A3ABD50A0
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AAAB01008961 Genomic DNA. Translation: EAA11974.5.
    RefSeqiXP_316738.5. XM_316738.5.

    Genome annotation databases

    EnsemblMetazoaiAGAP004656-RA; AGAP004656-PA; AGAP004656.
    GeneIDi1277307.
    KEGGiaga:AgaP_AGAP004656.
    VectorBaseiAGAP004656. Anopheles gambiae.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AAAB01008961 Genomic DNA. Translation: EAA11974.5 .
    RefSeqi XP_316738.5. XM_316738.5.

    3D structure databases

    ModBasei Search...

    Protein-protein interaction databases

    STRINGi 7165.AGAP004656-PA.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblMetazoai AGAP004656-RA ; AGAP004656-PA ; AGAP004656 .
    GeneIDi 1277307.
    KEGGi aga:AgaP_AGAP004656.
    VectorBasei AGAP004656. Anopheles gambiae.

    Phylogenomic databases

    eggNOGi COG2940.
    HOGENOMi HOG000046762.
    KOi K11424.
    OrthoDBi EOG7B05CD.
    PhylomeDBi Q7Q504.

    Family and domain databases

    Gene3Di 3.30.40.10. 1 hit.
    InterProi IPR006560. AWS.
    IPR003616. Post-SET_dom.
    IPR000313. PWWP_dom.
    IPR001214. SET_dom.
    IPR011011. Znf_FYVE_PHD.
    IPR001965. Znf_PHD.
    IPR013083. Znf_RING/FYVE/PHD.
    [Graphical view ]
    Pfami PF00855. PWWP. 2 hits.
    PF00856. SET. 1 hit.
    [Graphical view ]
    SMARTi SM00570. AWS. 1 hit.
    SM00249. PHD. 4 hits.
    SM00508. PostSET. 1 hit.
    SM00317. SET. 1 hit.
    [Graphical view ]
    SUPFAMi SSF57903. SSF57903. 1 hit.
    PROSITEi PS51215. AWS. 1 hit.
    PS50868. POST_SET. 1 hit.
    PS50812. PWWP. 2 hits.
    PS50280. SET. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The genome sequence of the malaria mosquito Anopheles gambiae."
      Holt R.A., Subramanian G.M., Halpern A., Sutton G.G., Charlab R., Nusskern D.R., Wincker P., Clark A.G., Ribeiro J.M.C., Wides R., Salzberg S.L., Loftus B.J., Yandell M.D., Majoros W.H., Rusch D.B., Lai Z., Kraft C.L., Abril J.F.
      , Anthouard V., Arensburger P., Atkinson P.W., Baden H., de Berardinis V., Baldwin D., Benes V., Biedler J., Blass C., Bolanos R., Boscus D., Barnstead M., Cai S., Center A., Chaturverdi K., Christophides G.K., Chrystal M.A.M., Clamp M., Cravchik A., Curwen V., Dana A., Delcher A., Dew I., Evans C.A., Flanigan M., Grundschober-Freimoser A., Friedli L., Gu Z., Guan P., Guigo R., Hillenmeyer M.E., Hladun S.L., Hogan J.R., Hong Y.S., Hoover J., Jaillon O., Ke Z., Kodira C.D., Kokoza E., Koutsos A., Letunic I., Levitsky A.A., Liang Y., Lin J.-J., Lobo N.F., Lopez J.R., Malek J.A., McIntosh T.C., Meister S., Miller J.R., Mobarry C., Mongin E., Murphy S.D., O'Brochta D.A., Pfannkoch C., Qi R., Regier M.A., Remington K., Shao H., Sharakhova M.V., Sitter C.D., Shetty J., Smith T.J., Strong R., Sun J., Thomasova D., Ton L.Q., Topalis P., Tu Z.J., Unger M.F., Walenz B., Wang A.H., Wang J., Wang M., Wang X., Woodford K.J., Wortman J.R., Wu M., Yao A., Zdobnov E.M., Zhang H., Zhao Q., Zhao S., Zhu S.C., Zhimulev I., Coluzzi M., della Torre A., Roth C.W., Louis C., Kalush F., Mural R.J., Myers E.W., Adams M.D., Smith H.O., Broder S., Gardner M.J., Fraser C.M., Birney E., Bork P., Brey P.T., Venter J.C., Weissenbach J., Kafatos F.C., Collins F.H., Hoffman S.L.
      Science 298:129-149(2002) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: PESTImported.

    Entry informationi

    Entry nameiQ7Q504_ANOGA
    AccessioniPrimary (citable) accession number: Q7Q504
    Entry historyi
    Integrated into UniProtKB/TrEMBL: December 15, 2003
    Last sequence update: July 27, 2011
    Last modified: September 3, 2014
    This is version 81 of the entry and version 5 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Caution

    The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

    Keywords - Technical termi

    Complete proteome, Reference proteome

    External Data

    Dasty 3

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