Q7Q504 (Q7Q504_ANOGA) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
AGAP004656-PA EMBL EAA11974.5

Gene names

ORF Names:

AgaP_AGAP004656 EMBL EAA11974.5

Organism

Anopheles gambiae (African malaria mosquito) [Reference proteome]

Taxonomic identifier

7165 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Protostomia › Ecdysozoa › Panarthropoda › Arthropoda › Mandibulata › Pancrustacea › Hexapoda › Insecta › Dicondylia › Pterygota › Neoptera › Endopterygota › Diptera › Nematocera › Culicimorpha › Culicoidea › Culicidae › Anophelinae › Anopheles › Cellia › Pyretophorus › gambiae species complex

Protein attributes

Sequence length	1259 AA.
Sequence status	Complete.
Protein existence	Predicted

General annotation (Comments)

Catalytic activity	S-adenosyl-L-methionine + L-lysine-[histone] = S-adenosyl-L-homocysteine + N(6)-methyl-L-lysine-[histone]. SAAS SAAS001214
Sequence similarities	Contains 1 SET domain. RuleBase RU004538 Contains 1 post-SET domain. RuleBase RU004541 SAAS SAAS001214
Caution	The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. EMBL EAA11974.5

Ontologies

Keywords
Cellular component	Nucleus SAAS SAAS001214
Domain	Zinc-finger SAAS SAAS001965
Ligand	Metal-binding Zinc
Molecular function	Methyltransferase SAAS SAAS001214 RuleBase RU004541 Transferase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	histone lysine methylation Inferred from electronic annotation. Source: GOC
Cellular_component	nucleus Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	histone-lysine N-methyltransferase activity Inferred from electronic annotation. Source: InterPro zinc ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q7Q504 [UniParc]. Last modified July 27, 2011. Version 5. Checksum: AAEEBE4A3ABD50A0	FASTA	1,259	142,173
	10 20 30 40 50 60 MFFAATAAAT NFETDLLSPT TTQKRVKSQE STPQSQKIAK QEPMSGSEMN ESGKENAFSD 70 80 90 100 110 120 QIRNHPTDEN SNTVVRVPGR YLLKQLSSSL SPKMTEINID TDRRVSRYGR HQKQKDNSDY 130 140 150 160 170 180 VPVDLMKYVG STPSKFKTKS ETDDPNSVNK TLETKPHSSD ELRTGSNDIS LSLTVVPLPL 190 200 210 220 230 240 IDGSIMKRPE EKQLLSMEEI KIVGMEEPYY TDKGSDNNCF MNNLLERKTS SDADSGKGSS 250 260 270 280 290 300 VDLAIIYRAG NLYWAAQTRK SIHWPCIVHV DPETDQITRL YGDKFLEVHV SYFGDRGRRA 310 320 330 340 350 360 WIKEHSILPF EGVDEYCTNA KNMEYGKLLK SALKSERWKN ACSIAERYMT LALSERIASF 370 380 390 400 410 420 DHEVKLELAR HKVMRHRMAI EGRIKNGASQ KMPALLPSDN SEVLEHWNKR DRSSSPESPE 430 440 450 460 470 480 YELLPGVFPT KNNPIKKIKF SPSMQNCILN DNRSPLDRPL HSMDSEENPP GSATKANGPK 490 500 510 520 530 540 AKTLGVSDLE NLNSTEYDDI LTFIRYYMFD GHTSYEVEKG LQLYVRGICN LKKHSNRGTE 550 560 570 580 590 600 RTVGRQRMHA LRKSYEILGI EPSAEVSTSL KTRNAHPVIK KEPKTLEEKF IFELDKNFLM 610 620 630 640 650 660 KGVPKGFVCY ICNRPNNVTK CSKCTLHLHL VCLANDPEEV VKMQELVDQK KLCCEKCSTT 670 680 690 700 710 720 SIVEKTCFIC NDEIPEKSNE QIYRCVVGKC TQAYHISCLQ LFPQVRQVSA STIICPYHTC 730 740 750 760 770 780 HTCVASEPRS TASMVKTTLA HCLKCPTSYH PSGNCIPAGS VLLTTTQLIC PKHTLEQIPL 790 800 810 820 830 840 NVNWCFICGK GGNLICCETC PLACHPVCLQ FTPPDEKYFC EGCESGRLPL YNEIVIAKMG 850 860 870 880 890 900 SFRWWPALTL PPSEIPQNML QLRHKPSDIC VKFFNTHDMS WLNRKRMYLY QREDSESLDG 910 920 930 940 950 960 SQSGSSMDKR YRSAMTEASK IFKILQTRKM LGPSASLSYS KAVPVYKKIK TNRYIPPLKP 970 980 990 1000 1010 1020 PSVNRQLDGV EDSVCRCQPS DDDPCGPTSA CLNRAIMMEC SSKTCPAKES CSNQRFTKRI 1030 1040 1050 1060 1070 1080 YPALEVRFFS DKGFGLVALE DLKSGQFVIE YVGEVINSEE FDRRVMMMQA AKETNYYFLT 1090 1100 1110 1120 1130 1140 VEPDLTIDAG PKGNVSRFIN HSCEPNCETQ KWTIGETRVI GLFAIKDINA GEELTFNYNL 1150 1160 1170 1180 1190 1200 ESLGNNKRVC LCGAGKCSGF IGEKYRPPNK KDIVISMKSE RSLKNGKKRV KIRRTKTTLT 1210 1220 1230 1240 1250 QKTTTNLSET KDTNNQLNDN DVVMISAQEA VIVDLVDENA SAYPLASVHI KQEKNDYNI

References

[1]

"The genome sequence of the malaria mosquito Anopheles gambiae." Holt R.A., Subramanian G.M., Halpern A., Sutton G.G., Charlab R., Nusskern D.R., Wincker P., Clark A.G., Ribeiro J.M.C., Wides R., Salzberg S.L., Loftus B.J., Yandell M.D., Majoros W.H., Rusch D.B., Lai Z., Kraft C.L., Abril J.F. , Anthouard V., Arensburger P., Atkinson P.W., Baden H., de Berardinis V., Baldwin D., Benes V., Biedler J., Blass C., Bolanos R., Boscus D., Barnstead M., Cai S., Center A., Chaturverdi K., Christophides G.K., Chrystal M.A.M., Clamp M., Cravchik A., Curwen V., Dana A., Delcher A., Dew I., Evans C.A., Flanigan M., Grundschober-Freimoser A., Friedli L., Gu Z., Guan P., Guigo R., Hillenmeyer M.E., Hladun S.L., Hogan J.R., Hong Y.S., Hoover J., Jaillon O., Ke Z., Kodira C.D., Kokoza E., Koutsos A., Letunic I., Levitsky A.A., Liang Y., Lin J.-J., Lobo N.F., Lopez J.R., Malek J.A., McIntosh T.C., Meister S., Miller J.R., Mobarry C., Mongin E., Murphy S.D., O'Brochta D.A., Pfannkoch C., Qi R., Regier M.A., Remington K., Shao H., Sharakhova M.V., Sitter C.D., Shetty J., Smith T.J., Strong R., Sun J., Thomasova D., Ton L.Q., Topalis P., Tu Z.J., Unger M.F., Walenz B., Wang A.H., Wang J., Wang M., Wang X., Woodford K.J., Wortman J.R., Wu M., Yao A., Zdobnov E.M., Zhang H., Zhao Q., Zhao S., Zhu S.C., Zhimulev I., Coluzzi M., della Torre A., Roth C.W., Louis C., Kalush F., Mural R.J., Myers E.W., Adams M.D., Smith H.O., Broder S., Gardner M.J., Fraser C.M., Birney E., Bork P., Brey P.T., Venter J.C., Weissenbach J., Kafatos F.C., Collins F.H., Hoffman S.L. Science 298:129-149(2002) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: PEST EMBL EAA11974.5.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AAAB01008961 Genomic DNA. Translation: EAA11974.5.
RefSeq	XP_316738.5. XM_316738.5.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblMetazoa	AGAP004656-RA; AGAP004656-PA; AGAP004656.
GeneID	1277307.
KEGG	aga:AgaP_AGAP004656.
VectorBase	AGAP004656. Anopheles gambiae.
Phylogenomic databases
eggNOG	COG2940.
HOGENOM	HOG000046762.
KO	K11424.
OrthoDB	EOG40CFZF.
PhylomeDB	Q7Q504.
Family and domain databases
Gene3D	3.30.40.10. 1 hit.
InterPro	IPR006560. AWS. IPR003616. Post-SET_dom. IPR000313. PWWP. IPR001214. SET_dom. IPR011011. Znf_FYVE_PHD. IPR001965. Znf_PHD. IPR013083. Znf_RING/FYVE/PHD. [Graphical view]
Pfam	PF00855. PWWP. 1 hit. PF00856. SET. 1 hit. [Graphical view]
SMART	SM00570. AWS. 1 hit. SM00249. PHD. 4 hits. SM00508. PostSET. 1 hit. SM00317. SET. 1 hit. [Graphical view]
SUPFAM	SSF57903. FYVE_PHD_ZnF. 1 hit.
PROSITE	PS51215. AWS. 1 hit. PS50868. POST_SET. 1 hit. PS50812. PWWP. 2 hits. PS50280. SET. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q7Q504_ANOGA

Accession

Primary (citable) accession number: Q7Q504

Entry history

Integrated into UniProtKB/TrEMBL:	December 15, 2003
Last sequence update:	July 27, 2011
Last modified:	May 1, 2013
This is version 72 of the entry and version 5 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)