Q7Q4A9 (Q7Q4A9_ANOGA) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
AGAP008317-PA EMBL EAA12198.4

Gene names

ORF Names:

AGAP008317, AgaP_AGAP008317 EMBL EAA12198.4

Organism

Anopheles gambiae (African malaria mosquito) [Reference proteome]

Taxonomic identifier

7165 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Protostomia › Ecdysozoa › Panarthropoda › Arthropoda › Mandibulata › Pancrustacea › Hexapoda › Insecta › Dicondylia › Pterygota › Neoptera › Endopterygota › Diptera › Nematocera › Culicimorpha › Culicoidea › Culicidae › Anophelinae › Anopheles › Cellia › Pyretophorus › gambiae species complex

Protein attributes

Sequence length	599 AA.
Sequence status	Complete.
Protein existence	Predicted

General annotation (Comments)

Catalytic activity	ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate. SAAS SAAS008266
Sequence similarities	Contains 1 SH2 domain. SAAS SAAS008266 Contains 1 SH3 domain. RuleBase RU003338 SAAS SAAS008266 Contains 1 protein kinase domain. SAAS SAAS008266
Caution	The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. EMBL EAA12198.4

Ontologies

Keywords
Domain	SH3 domain SAAS SAAS008266 RuleBase RU003338
Ligand	ATP-binding SAAS SAAS008266 Nucleotide-binding
Molecular function	Kinase Transferase Tyrosine-protein kinase SAAS SAAS008266
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Molecular_function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW protein tyrosine kinase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q7Q4A9 [UniParc]. Last modified October 23, 2007. Version 4. Checksum: 55C4053A77E7E2F8	FASTA	599	67,096
	10 20 30 40 50 60 MIPCVSLTES SVLGNMKERV KEMRVFGCRL NFWNNVTLNF GSNKGKCTGS SPAQNSTRST 70 80 90 100 110 120 SPNRASFASR IFSLSLLERL LPGSLLGGGP GDSGKGEIFS HDFISGWASP TVNSFKTASL 130 140 150 160 170 180 NGVGLHVNGG GDLNMPGGPT VTPGTPNTKA KDVSPRVKIV VALYPFKAIE SGDLSLEKNA 190 200 210 220 230 240 EYEVIDDSQE HWWKVKDQHG TIGYIPSNYV KEKELLGLQK YDWYVGDMSR QRAESLLKQN 250 260 270 280 290 300 DKEGCFVVRK SSTKGLYTLS LHTKVPQSHV KHYHIKQNAR SEFYLSEKHC CETIPDLINY 310 320 330 340 350 360 HRHNSGGLAC RLKTSPCDRP VPPTAGLSHD KWEIHPSELM ILEELGSGQF GVVRRAKWRG 370 380 390 400 410 420 SIDTAVKMMK VGTMSEDDFI EEAKVMTKLQ HPNLVQLYGV CSKHRPIYII TEYMKHGSLL 430 440 450 460 470 480 NYLRRHEQSL IGNMGLLLDM CIQVCKGMSY LERHNYIHRD LAARNCLVGS ENTVKVADFG 490 500 510 520 530 540 LARYVLDDQY TSSGGTKFPI KWAPPEVLNY TRFSSKSDVW AYGVLMWEVF TCGKMPYGRL 550 560 570 580 590 KNTEVVERVQ RGIILEKPKA CAKEIYDVMK KCWSHSPEDR PGFRILKDQL AAVAQGLTD

References

[1]

"The genome sequence of the malaria mosquito Anopheles gambiae." Holt R.A., Subramanian G.M., Halpern A., Sutton G.G., Charlab R., Nusskern D.R., Wincker P., Clark A.G., Ribeiro J.M.C., Wides R., Salzberg S.L., Loftus B.J., Yandell M.D., Majoros W.H., Rusch D.B., Lai Z., Kraft C.L., Abril J.F. , Anthouard V., Arensburger P., Atkinson P.W., Baden H., de Berardinis V., Baldwin D., Benes V., Biedler J., Blass C., Bolanos R., Boscus D., Barnstead M., Cai S., Center A., Chaturverdi K., Christophides G.K., Chrystal M.A.M., Clamp M., Cravchik A., Curwen V., Dana A., Delcher A., Dew I., Evans C.A., Flanigan M., Grundschober-Freimoser A., Friedli L., Gu Z., Guan P., Guigo R., Hillenmeyer M.E., Hladun S.L., Hogan J.R., Hong Y.S., Hoover J., Jaillon O., Ke Z., Kodira C.D., Kokoza E., Koutsos A., Letunic I., Levitsky A.A., Liang Y., Lin J.-J., Lobo N.F., Lopez J.R., Malek J.A., McIntosh T.C., Meister S., Miller J.R., Mobarry C., Mongin E., Murphy S.D., O'Brochta D.A., Pfannkoch C., Qi R., Regier M.A., Remington K., Shao H., Sharakhova M.V., Sitter C.D., Shetty J., Smith T.J., Strong R., Sun J., Thomasova D., Ton L.Q., Topalis P., Tu Z.J., Unger M.F., Walenz B., Wang A.H., Wang J., Wang M., Wang X., Woodford K.J., Wortman J.R., Wu M., Yao A., Zdobnov E.M., Zhang H., Zhao Q., Zhao S., Zhu S.C., Zhimulev I., Coluzzi M., della Torre A., Roth C.W., Louis C., Kalush F., Mural R.J., Myers E.W., Adams M.D., Smith H.O., Broder S., Gardner M.J., Fraser C.M., Birney E., Bork P., Brey P.T., Venter J.C., Weissenbach J., Kafatos F.C., Collins F.H., Hoffman S.L. Science 298:129-149(2002) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: PEST EMBL EAA12198.4.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AAAB01008964 Genomic DNA. Translation: EAA12198.4.
RefSeq	XP_317149.4. XM_317149.4.
3D structure databases
ProteinModelPortal	Q7Q4A9.
SMR	Q7Q4A9. Positions 334-590.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1277670.
KEGG	aga:AgaP_AGAP008317.
VectorBase	AGAP008317. Anopheles gambiae.
Phylogenomic databases
eggNOG	COG0515.
HOGENOM	HOG000233859.
KO	K07364.
OMA	HPSELMI.
OrthoDB	EOG40P2P1.
PhylomeDB	Q7Q4A9.
Family and domain databases
Gene3D	3.30.505.10. 1 hit.
InterPro	IPR011009. Kinase-like_dom. IPR000719. Prot_kinase_cat_dom. IPR017441. Protein_kinase_ATP_BS. IPR001245. Ser-Thr/Tyr_kinase_cat_dom. IPR000980. SH2. IPR001452. SH3_domain. IPR008266. Tyr_kinase_AS. IPR020635. Tyr_kinase_cat_dom. [Graphical view]
Pfam	PF07714. Pkinase_Tyr. 1 hit. PF00017. SH2. 1 hit. PF00018. SH3_1. 1 hit. [Graphical view]
PRINTS	PR00401. SH2DOMAIN. PR00109. TYRKINASE.
SMART	SM00252. SH2. 1 hit. SM00326. SH3. 1 hit. SM00219. TyrKc. 1 hit. [Graphical view]
SUPFAM	SSF56112. Kinase_like. 1 hit. SSF50044. SH3. 1 hit.
PROSITE	PS00107. PROTEIN_KINASE_ATP. 1 hit. PS50011. PROTEIN_KINASE_DOM. 1 hit. PS00109. PROTEIN_KINASE_TYR. 1 hit. PS50001. SH2. 1 hit. PS50002. SH3. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q7Q4A9_ANOGA

Accession

Primary (citable) accession number: Q7Q4A9

Entry history

Integrated into UniProtKB/TrEMBL:	December 15, 2003
Last sequence update:	October 23, 2007
Last modified:	May 1, 2013
This is version 91 of the entry and version 4 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)