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Q7Q2T3 (Q7Q2T3_ANOGA) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 54. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
4-hydroxyphenylpyruvate dioxygenase PIRNR PIRNR009283
Gene names
ORF Names:AGAP004802, AgaP_AGAP004802 EMBL EAA13250.3
OrganismAnopheles gambiae (African malaria mosquito)
Taxonomic identifier7165 [NCBI]
Taxonomic lineageEukaryotaMetazoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraNematoceraCulicoideaCulicidaeAnophelinaeAnopheles

Protein attributes

Sequence length381 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Cofactor

Binds 1 iron ion per subunit By similarity. PIRSR PIRSR009283-1

Sequence similarities

Belongs to the 4HPPD family. PIRSR PIRSR009283-1 PIRNR PIRNR009283

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data. EMBL EAA13250.3

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Metal binding1831Iron By similarity PIRSR PIRSR009283-1
Metal binding2661Iron By similarity PIRSR PIRSR009283-1
Metal binding3491Iron By similarity PIRSR PIRSR009283-1

Sequences

Sequence LengthMass (Da)Tools
Q7Q2T3 [UniParc].

Last modified October 23, 2007. Version 3.
Checksum: 5FF8941D802204A1

FASTA38143,836
        10         20         30         40         50         60 
MTTYTDKGPK PDGGKFLSFD HITFYVGNAK QAASFYTTRF GFEDYAYQGL ETGSRQLVKH 

        70         80         90        100        110        120 
AVRQDRIVFV FVSAYEPGHR ELGDHLVRHG DGVKDVAFEV EDLDVIVRRA KERGAKVVRD 

       130        140        150        160        170        180 
VWEESDEHGT VRFATVQTYG DTLHTFVERH RYRGLFLPGF KPPLHKDVLL RMLPTVGLNF 

       190        200        210        220        230        240 
IDHVVGNQPD LQMESVAAWY EKMLMFHRFW SVDDSQIHTE YSALRSIVMT NYEETIKMPI 

       250        260        270        280        290        300 
NEPAKGKKKS QIEEYVEYYG GAGVQHIALN TSDIIGAIRN LRARGQQFLS IPDTYYDQLR 

       310        320        330        340        350        360 
QRLKSSSVKI KEDLAVLQEL KILIDYDENG YLLQIFSKNM QDRPTLFIEV IQRHNHNGFG 

       370        380 
AGNFKALFEA IEAEQEKRGN L 

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References

[1]"The genome sequence of the malaria mosquito Anopheles gambiae."
Holt R.A., Subramanian G.M., Halpern A., Sutton G.G., Charlab R., Nusskern D.R., Wincker P., Clark A.G., Ribeiro J.M.C., Wides R., Salzberg S.L., Loftus B.J., Yandell M.D., Majoros W.H., Rusch D.B., Lai Z., Kraft C.L., Abril J.F. expand/collapse author list , Anthouard V., Arensburger P., Atkinson P.W., Baden H., de Berardinis V., Baldwin D., Benes V., Biedler J., Blass C., Bolanos R., Boscus D., Barnstead M., Cai S., Center A., Chaturverdi K., Christophides G.K., Chrystal M.A.M., Clamp M., Cravchik A., Curwen V., Dana A., Delcher A., Dew I., Evans C.A., Flanigan M., Grundschober-Freimoser A., Friedli L., Gu Z., Guan P., Guigo R., Hillenmeyer M.E., Hladun S.L., Hogan J.R., Hong Y.S., Hoover J., Jaillon O., Ke Z., Kodira C.D., Kokoza E., Koutsos A., Letunic I., Levitsky A.A., Liang Y., Lin J.-J., Lobo N.F., Lopez J.R., Malek J.A., McIntosh T.C., Meister S., Miller J.R., Mobarry C., Mongin E., Murphy S.D., O'Brochta D.A., Pfannkoch C., Qi R., Regier M.A., Remington K., Shao H., Sharakhova M.V., Sitter C.D., Shetty J., Smith T.J., Strong R., Sun J., Thomasova D., Ton L.Q., Topalis P., Tu Z.J., Unger M.F., Walenz B., Wang A.H., Wang J., Wang M., Wang X., Woodford K.J., Wortman J.R., Wu M., Yao A., Zdobnov E.M., Zhang H., Zhao Q., Zhao S., Zhu S.C., Zhimulev I., Coluzzi M., della Torre A., Roth C.W., Louis C., Kalush F., Mural R.J., Myers E.W., Adams M.D., Smith H.O., Broder S., Gardner M.J., Fraser C.M., Birney E., Bork P., Brey P.T., Venter J.C., Weissenbach J., Kafatos F.C., Collins F.H., Hoffman S.L.
Science 298:129-149(2002) [PubMed: 12364791] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: PEST.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AAAB01008968 Genomic DNA. Translation: EAA13250.3.
RefSeqXP_318007.3. XM_318007.4.

3D structure databases

ProteinModelPortalQ7Q2T3.
SMRQ7Q2T3. Positions 8-366.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ7Q2T3.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaAGAP004802-RA; AGAP004802-PA; AGAP004802.
GeneID1278421.
KEGGaga:AgaP_AGAP004802.
VectorBaseAGAP004802. Anopheles gambiae.

Phylogenomic databases

eggNOGinNOG04037.
GeneTreeEMGT00050000016473.
HOGENOMHBG680392.
OMACKLNFID.
OrthoDBEOG4X69QS.
PhylomeDBQ7Q2T3.

Family and domain databases

InterProIPR005956. 4OHPhenylPyrv_dOase.
IPR004360. Glyas_Fos-R_dOase.
IPR018146. Glyoxalase_1_CS.
[Graphical view]
KOK00457.
PANTHERPTHR11959. HPP_dOase. 1 hit.
PfamPF00903. Glyoxalase. 2 hits.
[Graphical view]
PIRSFPIRSF009283. HPP_dOase. 1 hit.
TIGRFAMsTIGR01263. 4HPPD. 1 hit.
PROSITEPS00934. GLYOXALASE_I_1. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ7Q2T3_ANOGA
AccessionPrimary (citable) accession number: Q7Q2T3
Entry history
Integrated into UniProtKB/TrEMBL: December 15, 2003
Last sequence update: October 23, 2007
Last modified: December 14, 2011
This is version 54 of the entry and version 3 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)