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Protein

Angiotensin-converting enzyme

Gene

ANCE7

Organism
Anopheles gambiae (African malaria mosquito)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Cofactori

Zn2+UniRule annotationNote: Binds 1 zinc ion per subunit.UniRule annotation

GO - Molecular functioni

Keywordsi

Molecular functionCarboxypeptidaseUniRule annotation, Hydrolase, MetalloproteaseUniRule annotation, Protease
LigandMetal-bindingUniRule annotation, ZincUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Angiotensin-converting enzymeUniRule annotation (EC:3.4.-.-UniRule annotation)
Gene namesi
Name:ANCE7Imported
Synonyms:1279163Imported
ORF Names:AgaP_AGAP009757Imported
OrganismiAnopheles gambiae (African malaria mosquito)Imported
Taxonomic identifieri7165 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraNematoceraCulicoideaCulicidaeAnophelinaeAnopheles
Proteomesi
  • UP000007062 Componenti: Chromosome 3R

Subcellular locationi

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 23Sequence analysisAdd BLAST23
ChainiPRO_501110235824 – 922Angiotensin-converting enzymeSequence analysisAdd BLAST899

Keywords - PTMi

GlycoproteinUniRule annotation

Proteomic databases

PaxDbiQ7Q1J9.

Interactioni

Protein-protein interaction databases

STRINGi7165.AGAP009757-PA.

Structurei

3D structure databases

ProteinModelPortaliQ7Q1J9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the peptidase M2 family.UniRule annotation

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiKOG3690. Eukaryota.
ENOG410XPJ3. LUCA.
HOGENOMiHOG000046399.
InParanoidiQ7Q1J9.
KOiK01283.
OMAiICQASAW.
OrthoDBiEOG091G033S.
PhylomeDBiQ7Q1J9.

Family and domain databases

CDDicd06461. M2_ACE. 1 hit.
InterProiView protein in InterPro
IPR001548. Peptidase_M2.
PANTHERiPTHR10514. PTHR10514. 1 hit.
PfamiView protein in Pfam
PF01401. Peptidase_M2. 1 hit.
PRINTSiPR00791. PEPDIPTASEA.

Sequencei

Sequence statusi: Complete.

Q7Q1J9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLKLLIKCTI GALFALQSIH CEADPQLNLP PLAPPGLEGR RPVTFPNGEA
60 70 80 90 100
SPTRVPLGVD GVVSGDGSSV HDRSRSERFG PPYDGDDDEE DERPNYPAQQ
110 120 130 140 150
PEGRANDYDR RDRQDSPYSY NDRNRYGGDR GYDRNQNRER YPGDRSPNPY
160 170 180 190 200
VSDVDNPLLY RDGGDRNRNR YVSDVENPLL YRDRTPYNPS RDYDDRNRYN
210 220 230 240 250
PNARPYNPND PSFGGRNPPD PNYRGPGQRD PNYRDQGFRE PGQRFPGDDR
260 270 280 290 300
TRYPDDPNYP YRSPEEERFR IENERRFRAE TEKLRAFLTE IDRKSSLECS
310 320 330 340 350
LNVAAQWNFE TNINDATQVE ALAAQQRYND FQRLLWDQMR RIDQTKIFDD
360 370 380 390 400
KLYRQVRLMS IIGPSALPPD QLDRYNRIVN DMLAIFNGAT ICAYEQPFEC
410 420 430 440 450
GLRLQPHLKD VSEQSIMAKS RDWNELQYTW LEWRRKSGRN MRDLFEQLVD
460 470 480 490 500
LTNDAGRVNN FTDAAAYWTF PYESRNFREE MEQVWREILP LYEMIHAYVR
510 520 530 540 550
RKLREFYGPD KINKNAPLPD HILGDMYGQS WQNILDIVIP YPGRSFLEVT
560 570 580 590 600
PEMQKQGYNP LVMFQIAEEF FVSMNMSAMP PDFWASSIVT QPPDRPILCQ
610 620 630 640 650
PSSWDFCTGK DYRVKMCTQV THKDFITVHH ELAHIQYFLN YRNNPKVFRD
660 670 680 690 700
GANPGFHEAI GDAISLSVAS PKHLQNLGLV QKSVDDTAHD INFLFSLAME
710 720 730 740 750
KVVFLPFALA LEAWRYDVFS KRVRKEQYNC HWWLLREEYG GVKPPVLRSE
760 770 780 790 800
LDFDPGAKYH VAANIPYIKY FFSNVLQFQI YRALCTASGQ YVPQDPSKPL
810 820 830 840 850
HKCDIYRQPA AGNILKKLME RGTSQPWQQV LQEVIGEGRL DGSALREFFR
860 870 880 890 900
PLEEWLRNEN LRNNEYVGWI YDGDYCKHSI ETANLQVFGG FYNVAVEVQL
910 920
TSWLMLMLSS WLVVMRTFAI VG
Length:922
Mass (Da):107,563
Last modified:October 23, 2007 - v3
Checksum:i6FCF280079F6046F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAAB01008980 Genomic DNA. Translation: EAA14517.3.
RefSeqiXP_318843.3. XM_318843.3.

Genome annotation databases

EnsemblMetazoaiAGAP009757-RA; AGAP009757-PA; AGAP009757.
GeneIDi1279163.
KEGGiaga:AgaP_AGAP009757.
VectorBaseiAGAP009757-RA; AGAP009757-PA; AGAP009757.

Similar proteinsi

Entry informationi

Entry nameiQ7Q1J9_ANOGA
AccessioniPrimary (citable) accession number: Q7Q1J9
Entry historyiIntegrated into UniProtKB/TrEMBL: December 15, 2003
Last sequence update: October 23, 2007
Last modified: October 25, 2017
This is version 88 of the entry and version 3 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported