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Protein
Submitted name:

AGAP012066-PA

Gene

AgaP_AGAP012066

Organism
Anopheles gambiae (African malaria mosquito)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
AGAP012066-PAImported
Gene namesi
ORF Names:AgaP_AGAP012066Imported
OrganismiAnopheles gambiae (African malaria mosquito)Imported
Taxonomic identifieri7165 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraNematoceraCulicoideaCulicidaeAnophelinaeAnopheles
Proteomesi
  • UP000007062 Componenti: Chromosome 3L

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Proteomic databases

PaxDbiQ7PZT1.

Interactioni

Protein-protein interaction databases

STRINGi7165.AGAP012066-PA.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini71 – 374Calpain catalyticInterPro annotationAdd BLAST304
Domaini693 – 724EF-handInterPro annotationAdd BLAST32

Sequence similaritiesi

Belongs to the peptidase C2 family.SAAS annotation

Phylogenomic databases

eggNOGiKOG0045. Eukaryota.
ENOG410XP0B. LUCA.
HOGENOMiHOG000232035.
InParanoidiQ7PZT1.
OMAiRWALLAN.
OrthoDBiEOG091G049E.
PhylomeDBiQ7PZT1.

Family and domain databases

CDDicd00214. Calpain_III. 1 hit.
cd00044. CysPc. 1 hit.
cd00051. EFh. 1 hit.
Gene3Di1.10.238.10. 1 hit.
InterProiIPR033883. C2_III.
IPR022684. Calpain_cysteine_protease.
IPR022682. Calpain_domain_III.
IPR022683. Calpain_III.
IPR011992. EF-hand-dom_pair.
IPR018247. EF_Hand_1_Ca_BS.
IPR002048. EF_hand_dom.
IPR001300. Peptidase_C2_calpain_cat.
[Graphical view]
PfamiPF01067. Calpain_III. 1 hit.
PF13405. EF-hand_6. 1 hit.
PF00648. Peptidase_C2. 1 hit.
[Graphical view]
PRINTSiPR00704. CALPAIN.
SMARTiSM00720. calpain_III. 1 hit.
SM00230. CysPc. 1 hit.
SM00054. EFh. 1 hit.
[Graphical view]
SUPFAMiSSF47473. SSF47473. 1 hit.
SSF49758. SSF49758. 1 hit.
PROSITEiPS50203. CALPAIN_CAT. 1 hit.
PS00018. EF_HAND_1. 1 hit.
PS50222. EF_HAND_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Q7PZT1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAAQACPTPN SSSAHVKGPS APFGSYRSST RFLPVTFEND EVRRPRYNST
60 70 80 90 100
ISNHHQHFYT LRQQCLSEGR LFEDPDFPAT DASIGMPKFI NVRWKRPKEL
110 120 130 140 150
TPTARFFIDG ASRLDICQGA LNDCWLLTAA TNLTSHPWLF RRVLPGDNSF
160 170 180 190 200
REEQQYAGAF HFRFWEFGQW VEVVIDDRLP TDATGKLLFG RSANGDEYWS
210 220 230 240 250
ALLEKAYAKF YGSYGALDGG TAREAMQDLT GGLTEFYQPK KMADGQEDQL
260 270 280 290 300
WDILRSGSEM GSLFACNLKS DPTGENVATK EGLLRGHSYS ITKVCSIPGL
310 320 330 340 350
VSGSDDIRLL RIRNPWGTGI EWNGRWSDKS REWKSLNQAE RKRVGLTVEN
360 370 380 390 400
DGEFWIELVD FMKHFDRLEV CHLSPELHSI EEDGAGDRTS STRRYRWELS
410 420 430 440 450
ALDGQWIRDT TAGGNISFLD TFPLNPQYTI HVQDGTTGSG VVIALMQKYR
460 470 480 490 500
RADSLPSLTI GFTVYRVTVE DLRQKPVPRE FFQHHDHAIV GGSIFINARE
510 520 530 540 550
ISCRLTLDAG LYLVIPSTFE PGEEGDYLLR IFTARGNTLC ENDATLCFGT
560 570 580 590 600
LDDRITEQGK FFDTPRWALL ANAFYNRAEG DKQLLNTASL CDILWEQFFR
610 620 630 640 650
PNVPKRPQPK QQTSGGSSPW RKFYSCVLQL CACFWIQSAV RKSRRAGEPI
660 670 680 690 700
VQEDQAHRGE LERIVKLLMG RIADGQDTIG YEQYRTIARD VYQWESVFRL
710 720 730 740 750
YDMDGSGTLD RRELRHALRS SGFNTNNRIL CRLQRLMVEL NRPQIELIEY
760
VLCAAECRHA I
Length:761
Mass (Da):86,699
Last modified:October 23, 2007 - v4
Checksum:i0253E21761F027BF
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei761Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAAB01008986 Genomic DNA. Translation: EAA00305.4.
RefSeqiXP_320459.4. XM_320459.4.

Genome annotation databases

EnsemblMetazoaiAGAP012066-RA; AGAP012066-PA; AGAP012066.
GeneIDi1280603.
KEGGiaga:AgaP_AGAP012066.
VectorBaseiAGAP012066-RA; AGAP012066-PA; AGAP012066.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAAB01008986 Genomic DNA. Translation: EAA00305.4.
RefSeqiXP_320459.4. XM_320459.4.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi7165.AGAP012066-PA.

Proteomic databases

PaxDbiQ7PZT1.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiAGAP012066-RA; AGAP012066-PA; AGAP012066.
GeneIDi1280603.
KEGGiaga:AgaP_AGAP012066.
VectorBaseiAGAP012066-RA; AGAP012066-PA; AGAP012066.

Phylogenomic databases

eggNOGiKOG0045. Eukaryota.
ENOG410XP0B. LUCA.
HOGENOMiHOG000232035.
InParanoidiQ7PZT1.
OMAiRWALLAN.
OrthoDBiEOG091G049E.
PhylomeDBiQ7PZT1.

Family and domain databases

CDDicd00214. Calpain_III. 1 hit.
cd00044. CysPc. 1 hit.
cd00051. EFh. 1 hit.
Gene3Di1.10.238.10. 1 hit.
InterProiIPR033883. C2_III.
IPR022684. Calpain_cysteine_protease.
IPR022682. Calpain_domain_III.
IPR022683. Calpain_III.
IPR011992. EF-hand-dom_pair.
IPR018247. EF_Hand_1_Ca_BS.
IPR002048. EF_hand_dom.
IPR001300. Peptidase_C2_calpain_cat.
[Graphical view]
PfamiPF01067. Calpain_III. 1 hit.
PF13405. EF-hand_6. 1 hit.
PF00648. Peptidase_C2. 1 hit.
[Graphical view]
PRINTSiPR00704. CALPAIN.
SMARTiSM00720. calpain_III. 1 hit.
SM00230. CysPc. 1 hit.
SM00054. EFh. 1 hit.
[Graphical view]
SUPFAMiSSF47473. SSF47473. 1 hit.
SSF49758. SSF49758. 1 hit.
PROSITEiPS50203. CALPAIN_CAT. 1 hit.
PS00018. EF_HAND_1. 1 hit.
PS50222. EF_HAND_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ7PZT1_ANOGA
AccessioniPrimary (citable) accession number: Q7PZT1
Entry historyi
Integrated into UniProtKB/TrEMBL: December 15, 2003
Last sequence update: October 23, 2007
Last modified: November 30, 2016
This is version 82 of the entry and version 4 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.