Q7PYU6 (ZGPAT_ANOGA) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Zinc finger CCCH-type with G patch domain-containing protein

Gene names

ORF Names:

AGAP002111

Organism

Anopheles gambiae (African malaria mosquito) [Reference proteome]

Taxonomic identifier

7165 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Protostomia › Ecdysozoa › Panarthropoda › Arthropoda › Mandibulata › Pancrustacea › Hexapoda › Insecta › Dicondylia › Pterygota › Neoptera › Endopterygota › Diptera › Nematocera › Culicimorpha › Culicoidea › Culicidae › Anophelinae › Anopheles › Cellia › Pyretophorus › gambiae species complex

Protein attributes

Sequence length	543 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Transcription repressor By similarity.
Subcellular location	Nucleus By similarity.
Sequence similarities	Contains 1 C3H1-type zinc finger. Contains 1 G-patch domain.

Ontologies

Keywords
Biological process	Transcription Transcription regulation
Cellular component	Nucleus
Domain	Zinc-finger
Ligand	DNA-binding Metal-binding Zinc
Molecular function	Repressor
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	regulation of transcription, DNA-dependent Inferred from electronic annotation. Source: UniProtKB-KW transcription, DNA-dependent Inferred from electronic annotation. Source: UniProtKB-KW
Cellular_component	nucleus Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	DNA binding Inferred from electronic annotation. Source: UniProtKB-KW zinc ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 543	543	Zinc finger CCCH-type with G patch domain-containing protein		PRO_0000385199
Regions
	Domain	335 – 381	47	G-patch
	Zinc finger	186 – 209	24	C3H1-type

Sequences

	Sequence		Length	Mass (Da)
	Q7PYU6 [UniParc]. Last modified October 23, 2007. Version 4. Checksum: 18C5B69818D97F94	FASTA	543	61,051
	10 20 30 40 50 60 MSVDELNQSI LQYKEQLEQI AQALQLTRDE TERSELNKLK SDLIELLELT VESLAATSDD 70 80 90 100 110 120 DDAPDTAGRA PPATADNPID DEFALFMREI KELQTEDSAA GEQAGEQTAT EPERQPNDDD 130 140 150 160 170 180 ADNDDDADDK LDLDGLVGSK CSAPHLHTWG STAYHNAMVC SLDADDLAHA TAKVLFTNPT 190 200 210 220 230 240 HREMLPCAYF LEGECRFTDE KCRYSHGEVV RLDQLRDYRA PQFERLRRAG SRALVKQSTR 250 260 270 280 290 300 LWCKGTVTEV DFDAKRCKVR LEEGKREQLE VPFEDLLPLD EDEDGQEAAE DSESDTDGAD 310 320 330 340 350 360 EEEADDEALR KALLVEKSLF HPAPDRRLGE WEEHTRGIGS KIMQKMGYIV GTGLGREGEG 370 380 390 400 410 420 IVVPVSAQVL PQGRSLDYCM ELREQSNGDK DLFSVEKKLV QLKRQEAKRA AKDYERQRAR 430 440 450 460 470 480 ESKSKDVFSF INEQVFSGAA GGESSRPNRN RPGALSRQEL KEHSCKNLNI ASLKLSEEIR 490 500 510 520 530 540 RTEADVERLK IALTRHRAGT PAADNLLRQI DAKRAEISRM QASEGNISRE QQLRSDKKKL TIF

References

[1]

"The genome sequence of the malaria mosquito Anopheles gambiae." Holt R.A., Subramanian G.M., Halpern A., Sutton G.G., Charlab R., Nusskern D.R., Wincker P., Clark A.G., Ribeiro J.M.C., Wides R., Salzberg S.L., Loftus B.J., Yandell M.D., Majoros W.H., Rusch D.B., Lai Z., Kraft C.L., Abril J.F. , Anthouard V., Arensburger P., Atkinson P.W., Baden H., de Berardinis V., Baldwin D., Benes V., Biedler J., Blass C., Bolanos R., Boscus D., Barnstead M., Cai S., Center A., Chaturverdi K., Christophides G.K., Chrystal M.A.M., Clamp M., Cravchik A., Curwen V., Dana A., Delcher A., Dew I., Evans C.A., Flanigan M., Grundschober-Freimoser A., Friedli L., Gu Z., Guan P., Guigo R., Hillenmeyer M.E., Hladun S.L., Hogan J.R., Hong Y.S., Hoover J., Jaillon O., Ke Z., Kodira C.D., Kokoza E., Koutsos A., Letunic I., Levitsky A.A., Liang Y., Lin J.-J., Lobo N.F., Lopez J.R., Malek J.A., McIntosh T.C., Meister S., Miller J.R., Mobarry C., Mongin E., Murphy S.D., O'Brochta D.A., Pfannkoch C., Qi R., Regier M.A., Remington K., Shao H., Sharakhova M.V., Sitter C.D., Shetty J., Smith T.J., Strong R., Sun J., Thomasova D., Ton L.Q., Topalis P., Tu Z.J., Unger M.F., Walenz B., Wang A.H., Wang J., Wang M., Wang X., Woodford K.J., Wortman J.R., Wu M., Yao A., Zdobnov E.M., Zhang H., Zhao Q., Zhao S., Zhu S.C., Zhimulev I., Coluzzi M., della Torre A., Roth C.W., Louis C., Kalush F., Mural R.J., Myers E.W., Adams M.D., Smith H.O., Broder S., Gardner M.J., Fraser C.M., Birney E., Bork P., Brey P.T., Venter J.C., Weissenbach J., Kafatos F.C., Collins F.H., Hoffman S.L. Science 298:129-149(2002) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: PEST.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AAAB01008987 Genomic DNA. Translation: EAA00977.4.
RefSeq	XP_320928.4. XM_320928.4.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	7165.AGAP002111-PA.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblMetazoa	AGAP002111-RA; AGAP002111-PA; AGAP002111.
GeneID	1281359.
KEGG	aga:AgaP_AGAP002111.
VectorBase	AGAP002111. Anopheles gambiae.
Organism-specific databases
CTD	1281359.
Phylogenomic databases
eggNOG	NOG241375.
HOGENOM	HOG000122451.
OMA	NELLADN.
OrthoDB	EOG444J1N.
PhylomeDB	Q7PYU6.
Family and domain databases
InterPro	IPR000467. G_patch_dom. IPR000571. Znf_CCCH. [Graphical view]
Pfam	PF01585. G-patch. 1 hit. [Graphical view]
SMART	SM00443. G_patch. 1 hit. [Graphical view]
PROSITE	PS50174. G_PATCH. 1 hit. PS50103. ZF_C3H1. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

ZGPAT_ANOGA

Accession

Primary (citable) accession number: Q7PYU6

Entry history

Integrated into UniProtKB/Swiss-Prot:	September 22, 2009
Last sequence update:	October 23, 2007
Last modified:	April 3, 2013
This is version 58 of the entry and version 4 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)