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Protein
Submitted name:

AGAP009100-PA

Gene

AgaP_AGAP009100

Organism
Anopheles gambiae (African malaria mosquito)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

Cofactori

Note: Binds 1 calcium ion per subunit.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei293 – 2931UniRule annotation
Active sitei352 – 3521UniRule annotation
Active sitei379 – 3791UniRule annotation

GO - Molecular functioni

  1. metal ion binding Source: UniProtKB-KW
  2. protein-glutamine gamma-glutamyltransferase activity Source: InterPro

GO - Biological processi

  1. peptide cross-linking Source: InterPro
Complete GO annotation...

Keywords - Ligandi

CalciumUniRule annotation, Metal-bindingUniRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
AGAP009100-PAImported
Gene namesi
ORF Names:AgaP_AGAP009100Imported
OrganismiAnopheles gambiae (African malaria mosquito)Imported
Taxonomic identifieri7165 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraNematoceraCulicoideaCulicidaeAnophelinaeAnopheles
ProteomesiUP000007062: Chromosome 3R

Structurei

3D structure databases

ProteinModelPortaliQ7PW40.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiNOG80379.
HOGENOMiHOG000231695.
InParanoidiQ7PW40.
KOiK05619.
OMAiRIITCYS.
OrthoDBiEOG712TVM.
PhylomeDBiQ7PW40.

Family and domain databases

Gene3Di2.60.40.10. 3 hits.
3.90.260.10. 1 hit.
InterProiIPR023608. Gln_gamma-glutamylTfrase_euk.
IPR013783. Ig-like_fold.
IPR014756. Ig_E-set.
IPR002931. Transglutaminase-like.
IPR008958. Transglutaminase_C.
IPR001102. Transglutaminase_N.
[Graphical view]
PANTHERiPTHR11590. PTHR11590. 1 hit.
PfamiPF00927. Transglut_C. 2 hits.
PF01841. Transglut_core. 1 hit.
PF00868. Transglut_N. 1 hit.
[Graphical view]
PIRSFiPIRSF000459. TGM_EBP42. 1 hit.
SMARTiSM00460. TGc. 1 hit.
[Graphical view]
SUPFAMiSSF49309. SSF49309. 2 hits.
SSF81296. SSF81296. 1 hit.

Sequencei

Sequence statusi: Fragment.

Q7PW40-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
QTDSPSADVL TVKSVDLCTE ENGKDHHTKR YELMSRDEYS GKIPKLVVRR
60 70 80 90 100
GQPFRLRLVC DRPYDRARDA LSLIFTVADE DQPTHGHGTL VGIPVNQFPE
110 120 130 140 150
QLGEPEEWGA AIEAINGDLL QVLVKPAATA PVGQWKLDID TKLLSEAFGK
160 170 180 190 200
SYSLPQAFYV LFNPWCPDDL VYMEEKAHRH EYVMSDTTLI YRGSYNRLRP
210 220 230 240 250
SVWKFGQFEK HVLDCSLLLI AKIGKVSATH RGDPVRVCRA ISAAVNSPDD
260 270 280 290 300
DGALMGNWSG DFSGGTPPTK WVGSVEILQQ FYKRQKPVKF AQCWVFAGVV
310 320 330 340 350
STICRAIGIP SRVVTNYSSA HDTQASLTVD YFVDKSGKIM EEMNADSIWN
360 370 380 390 400
YHVWNEVWMQ RPDLGISSDG DYGGWQAIDA TPQESSDGMF RCGPASVLAV
410 420 430 440 450
KLGEVLKPYD NNFLFAEVNA DKVFWRYTGP HHPLKLLRKD VLGIGLFIST
460 470 480 490 500
KAVGRWERED ITSSYKFAEK SEEERATMLK ALKQANSYFS RYYLNEEFNE
510 520 530 540 550
VYFNFELRDD IKIGEPFSVI LTVKNRSSEN RHVVEGSLHV DTVLYTGKDR
560 570 580 590 600
ESVKVDKFSV TLEPGTEESI RMIVEFHEYY RKLRDQAAFN ISCMATVLDT
610 620 630 640 650
EFEFYAQDDF RVRKPDIKIT LLGKPVSQAP VDVQFTLENP LPIPLHKGLF
660 670 680 690 700
HLEGSGIGKP LLFKHAEIAP GEKVSNTFTM TPPYSGRLTL AAKFTSKELD
710 720 730
DVDGFLAFLA HPRPEDIITE VEDNVIVART DVID
Length:734
Mass (Da):82,847
Last modified:December 7, 2004 - v2
Checksum:i37C943E7907EA691
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAAB01008984 Genomic DNA. Translation: EAA14718.2.
RefSeqiXP_319850.2. XM_319850.2.

Genome annotation databases

EnsemblMetazoaiAGAP009100-RA; AGAP009100-PA; AGAP009100.
GeneIDi1280052.
KEGGiaga:AgaP_AGAP009100.
VectorBaseiAGAP009100. Anopheles gambiae.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAAB01008984 Genomic DNA. Translation: EAA14718.2.
RefSeqiXP_319850.2. XM_319850.2.

3D structure databases

ProteinModelPortaliQ7PW40.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiAGAP009100-RA; AGAP009100-PA; AGAP009100.
GeneIDi1280052.
KEGGiaga:AgaP_AGAP009100.
VectorBaseiAGAP009100. Anopheles gambiae.

Phylogenomic databases

eggNOGiNOG80379.
HOGENOMiHOG000231695.
InParanoidiQ7PW40.
KOiK05619.
OMAiRIITCYS.
OrthoDBiEOG712TVM.
PhylomeDBiQ7PW40.

Family and domain databases

Gene3Di2.60.40.10. 3 hits.
3.90.260.10. 1 hit.
InterProiIPR023608. Gln_gamma-glutamylTfrase_euk.
IPR013783. Ig-like_fold.
IPR014756. Ig_E-set.
IPR002931. Transglutaminase-like.
IPR008958. Transglutaminase_C.
IPR001102. Transglutaminase_N.
[Graphical view]
PANTHERiPTHR11590. PTHR11590. 1 hit.
PfamiPF00927. Transglut_C. 2 hits.
PF01841. Transglut_core. 1 hit.
PF00868. Transglut_N. 1 hit.
[Graphical view]
PIRSFiPIRSF000459. TGM_EBP42. 1 hit.
SMARTiSM00460. TGc. 1 hit.
[Graphical view]
SUPFAMiSSF49309. SSF49309. 2 hits.
SSF81296. SSF81296. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "The genome sequence of the malaria mosquito Anopheles gambiae."
    Holt R.A., Subramanian G.M., Halpern A., Sutton G.G., Charlab R., Nusskern D.R., Wincker P., Clark A.G., Ribeiro J.M., Wides R., Salzberg S.L., Loftus B., Yandell M., Majoros W.H., Rusch D.B., Lai Z., Kraft C.L., Abril J.F.
    , Anthouard V., Arensburger P., Atkinson P.W., Baden H., de Berardinis V., Baldwin D., Benes V., Biedler J., Blass C., Bolanos R., Boscus D., Barnstead M., Cai S., Center A., Chaturverdi K., Christophides G.K., Chrystal M.A., Clamp M., Cravchik A., Curwen V., Dana A., Delcher A., Dew I., Evans C.A., Flanigan M., Grundschober-Freimoser A., Friedli L., Gu Z., Guan P., Guigo R., Hillenmeyer M.E., Hladun S.L., Hogan J.R., Hong Y.S., Hoover J., Jaillon O., Ke Z., Kodira C., Kokoza E., Koutsos A., Letunic I., Levitsky A., Liang Y., Lin J.J., Lobo N.F., Lopez J.R., Malek J.A., McIntosh T.C., Meister S., Miller J., Mobarry C., Mongin E., Murphy S.D., O'Brochta D.A., Pfannkoch C., Qi R., Regier M.A., Remington K., Shao H., Sharakhova M.V., Sitter C.D., Shetty J., Smith T.J., Strong R., Sun J., Thomasova D., Ton L.Q., Topalis P., Tu Z., Unger M.F., Walenz B., Wang A., Wang J., Wang M., Wang X., Woodford K.J., Wortman J.R., Wu M., Yao A., Zdobnov E.M., Zhang H., Zhao Q., Zhao S., Zhu S.C., Zhimulev I., Coluzzi M., della Torre A., Roth C.W., Louis C., Kalush F., Mural R.J., Myers E.W., Adams M.D., Smith H.O., Broder S., Gardner M.J., Fraser C.M., Birney E., Bork P., Brey P.T., Venter J.C., Weissenbach J., Kafatos F.C., Collins F.H., Hoffman S.L.
    Science 298:129-149(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: PESTImported.

Entry informationi

Entry nameiQ7PW40_ANOGA
AccessioniPrimary (citable) accession number: Q7PW40
Entry historyi
Integrated into UniProtKB/TrEMBL: December 15, 2003
Last sequence update: December 7, 2004
Last modified: January 7, 2015
This is version 80 of the entry and version 2 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.