Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Inositol-1-monophosphatase

Gene

1277154

Organism
Anopheles gambiae (African malaria mosquito)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

Myo-inositol phosphate + H2O = myo-inositol + phosphate.UniRule annotation

Cofactori

Mg2+UniRule annotation

Pathwayi: myo-inositol biosynthesis

This protein is involved in step 2 of the subpathway that synthesizes myo-inositol from D-glucose 6-phosphate.UniRule annotation
Proteins known to be involved in the 2 steps of the subpathway in this organism are:
  1. no protein annotated in this organism
  2. Inositol-1-monophosphatase, Inositol-1-monophosphatase (AgaP_AGAP010463), Inositol-1-monophosphatase (1277154)
This subpathway is part of the pathway myo-inositol biosynthesis, which is itself part of Polyol metabolism.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes myo-inositol from D-glucose 6-phosphate, the pathway myo-inositol biosynthesis and in Polyol metabolism.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolaseUniRule annotation
LigandMagnesiumUniRule annotation, Metal-bindingUniRule annotation

Enzyme and pathway databases

UniPathwayiUPA00823; UER00788

Names & Taxonomyi

Protein namesi
Recommended name:
Inositol-1-monophosphataseUniRule annotation (EC:3.1.3.25UniRule annotation)
Gene namesi
Name:1277154Imported
ORF Names:AgaP_AGAP006570Imported
OrganismiAnopheles gambiae (African malaria mosquito)Imported
Taxonomic identifieri7165 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraNematoceraCulicoideaCulicidaeAnophelinaeAnopheles
Proteomesi
  • UP000007062 Componenti: Chromosome 2L

Interactioni

Protein-protein interaction databases

STRINGi7165.AGAP006570-PA

Structurei

3D structure databases

ProteinModelPortaliQ7PNQ6
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the inositol monophosphatase superfamily.UniRule annotation

Phylogenomic databases

eggNOGiKOG2951 Eukaryota
COG0483 LUCA
HOGENOMiHOG000282238
InParanoidiQ7PNQ6
KOiK01092
OMAiNNYAEFC
OrthoDBiEOG091G0D21
PhylomeDBiQ7PNQ6

Family and domain databases

CDDicd01639 IMPase, 1 hit
InterProiView protein in InterPro
IPR033942 IMPase
IPR020583 Inositol_monoP_metal-BS
IPR020552 Inositol_monoPase_Li-sen
IPR000760 Inositol_monophosphatase-like
IPR020550 Inositol_monophosphatase_CS
PfamiView protein in Pfam
PF00459 Inositol_P, 1 hit
PRINTSiPR00377 IMPHPHTASES
PR00378 LIIMPHPHTASE
PROSITEiView protein in PROSITE
PS00629 IMP_1, 1 hit
PS00630 IMP_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q7PNQ6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MALNLDECYE HVLGLVETAG SLIASRNSQR KRVVEKSSNI DLLTETDQQV
60 70 80 90 100
ERMLMEGITA KYPDHKFIGE EETSEGKKAE LTDAPTWIID PVDGTMNFVH
110 120 130 140 150
SFPHSCISIA LLVGKVTEIA IIYNPIVGQK FTAQRGKGAF LNGTPIRVSG
160 170 180 190 200
ETAFERALAT TEFGTSREED KTRVVLENIG KLVRQIHGLR SLGSAALNMA
210 220 230 240 250
MVALGGADFN YEFGIHAWDI AAGDLLVREA GGVCLDPAGG PLDLMSRRVL
260 270
CASTQELADK VVQTLTQYYP EPRD
Length:274
Mass (Da):29,911
Last modified:October 23, 2007 - v4
Checksum:i76AB663A3A76D130
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAAB01008960 Genomic DNA Translation: EAA11769.5
RefSeqiXP_316595.4, XM_316595.4

Genome annotation databases

EnsemblMetazoaiAGAP006570-RA; AGAP006570-PA; AGAP006570
GeneIDi1277154
KEGGiaga:AgaP_AGAP006570
VectorBaseiAGAP006570-RA; AGAP006570-PA; AGAP006570

Similar proteinsi

Entry informationi

Entry nameiQ7PNQ6_ANOGA
AccessioniPrimary (citable) accession number: Q7PNQ6
Entry historyiIntegrated into UniProtKB/TrEMBL: December 15, 2003
Last sequence update: October 23, 2007
Last modified: May 23, 2018
This is version 94 of the entry and version 4 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health