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Protein

Inositol-1-monophosphatase

Gene

1277154

Organism
Anopheles gambiae (African malaria mosquito)
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

Myo-inositol phosphate + H2O = myo-inositol + phosphate.UniRule annotation

Cofactori

Mg2+UniRule annotation

Pathwayi: myo-inositol biosynthesis

This protein is involved in step 2 of the subpathway that synthesizes myo-inositol from D-glucose 6-phosphate.UniRule annotation
Proteins known to be involved in the 2 steps of the subpathway in this organism are:
  1. no protein annotated in this organism
  2. Inositol-1-monophosphatase (1272576), Inositol-1-monophosphatase (AgaP_AGAP010463), Inositol-1-monophosphatase (1277154)
This subpathway is part of the pathway myo-inositol biosynthesis, which is itself part of Polyol metabolism.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes myo-inositol from D-glucose 6-phosphate, the pathway myo-inositol biosynthesis and in Polyol metabolism.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolaseUniRule annotation
LigandMagnesiumUniRule annotation, Metal-bindingUniRule annotation

Enzyme and pathway databases

UniPathwayiUPA00823; UER00788.

Names & Taxonomyi

Protein namesi
Recommended name:
Inositol-1-monophosphataseUniRule annotation (EC:3.1.3.25UniRule annotation)
Gene namesi
Name:1277154Imported
ORF Names:AgaP_AGAP006570Imported
OrganismiAnopheles gambiae (African malaria mosquito)Imported
Taxonomic identifieri7165 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraNematoceraCulicoideaCulicidaeAnophelinaeAnopheles
Proteomesi
  • UP000007062 Componenti: Chromosome 2L

PTM / Processingi

Proteomic databases

PaxDbiQ7PNQ6.

Interactioni

Protein-protein interaction databases

STRINGi7165.AGAP006570-PA.

Structurei

3D structure databases

ProteinModelPortaliQ7PNQ6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the inositol monophosphatase family.UniRule annotation

Phylogenomic databases

eggNOGiKOG2951. Eukaryota.
COG0483. LUCA.
HOGENOMiHOG000282238.
InParanoidiQ7PNQ6.
KOiK01092.
OMAiNNYAEFC.
OrthoDBiEOG091G0D21.
PhylomeDBiQ7PNQ6.

Family and domain databases

CDDicd01639. IMPase. 1 hit.
InterProiView protein in InterPro
IPR033942. IMPase.
IPR020583. Inositol_monoP_metal-BS.
IPR020552. Inositol_monoPase_Li-sen.
IPR000760. Inositol_monophosphatase-like.
IPR020550. Inositol_monophosphatase_CS.
PANTHERiPTHR20854. PTHR20854. 1 hit.
PfamiView protein in Pfam
PF00459. Inositol_P. 1 hit.
PRINTSiPR00377. IMPHPHTASES.
PR00378. LIIMPHPHTASE.
PROSITEiView protein in PROSITE
PS00629. IMP_1. 1 hit.
PS00630. IMP_2. 1 hit.

Sequencei

Sequence statusi: Complete.

Q7PNQ6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MALNLDECYE HVLGLVETAG SLIASRNSQR KRVVEKSSNI DLLTETDQQV
60 70 80 90 100
ERMLMEGITA KYPDHKFIGE EETSEGKKAE LTDAPTWIID PVDGTMNFVH
110 120 130 140 150
SFPHSCISIA LLVGKVTEIA IIYNPIVGQK FTAQRGKGAF LNGTPIRVSG
160 170 180 190 200
ETAFERALAT TEFGTSREED KTRVVLENIG KLVRQIHGLR SLGSAALNMA
210 220 230 240 250
MVALGGADFN YEFGIHAWDI AAGDLLVREA GGVCLDPAGG PLDLMSRRVL
260 270
CASTQELADK VVQTLTQYYP EPRD
Length:274
Mass (Da):29,911
Last modified:October 23, 2007 - v4
Checksum:i76AB663A3A76D130
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAAB01008960 Genomic DNA. Translation: EAA11769.5.
RefSeqiXP_316595.4. XM_316595.4.

Genome annotation databases

EnsemblMetazoaiAGAP006570-RA; AGAP006570-PA; AGAP006570.
GeneIDi1277154.
KEGGiaga:AgaP_AGAP006570.
VectorBaseiAGAP006570-RA; AGAP006570-PA; AGAP006570.

Similar proteinsi

Entry informationi

Entry nameiQ7PNQ6_ANOGA
AccessioniPrimary (citable) accession number: Q7PNQ6
Entry historyiIntegrated into UniProtKB/TrEMBL: December 15, 2003
Last sequence update: October 23, 2007
Last modified: August 30, 2017
This is version 89 of the entry and version 4 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported