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Protein

Angiotensin-converting enzyme

Gene

ANCE6

Organism
Anopheles gambiae (African malaria mosquito)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Cofactori

Zn2+UniRule annotationNote: Binds 1 zinc ion per subunit.UniRule annotation

GO - Molecular functioni

Keywordsi

Molecular functionCarboxypeptidaseUniRule annotation, Hydrolase, MetalloproteaseUniRule annotation, Protease
LigandMetal-bindingUniRule annotation, ZincUniRule annotation

Protein family/group databases

MEROPSiM02.003

Names & Taxonomyi

Protein namesi
Recommended name:
Angiotensin-converting enzymeUniRule annotation (EC:3.4.-.-UniRule annotation)
Gene namesi
Name:ANCE6Imported
Synonyms:1279162Imported
ORF Names:AgaP_AGAP009756Imported
OrganismiAnopheles gambiae (African malaria mosquito)Imported
Taxonomic identifieri7165 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraNematoceraCulicoideaCulicidaeAnophelinaeAnopheles
Proteomesi
  • UP000007062 Componenti: Chromosome 3R

Subcellular locationi

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 19Sequence analysisAdd BLAST19
ChainiPRO_501431094020 – 633Angiotensin-converting enzymeSequence analysisAdd BLAST614

Keywords - PTMi

GlycoproteinUniRule annotation

Interactioni

Protein-protein interaction databases

STRINGi7165.AGAP009756-PA

Structurei

3D structure databases

ProteinModelPortaliQ7PM22
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the peptidase M2 family.UniRule annotation

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiKOG3690 Eukaryota
ENOG410XPJ3 LUCA
HOGENOMiHOG000292210
InParanoidiQ7PM22
KOiK01283
OMAiEAKQYDP
OrthoDBiEOG091G033S
PhylomeDBiQ7PM22

Family and domain databases

CDDicd06461 M2_ACE, 1 hit
InterProiView protein in InterPro
IPR001548 Peptidase_M2
PANTHERiPTHR10514 PTHR10514, 1 hit
PfamiView protein in Pfam
PF01401 Peptidase_M2, 1 hit
PRINTSiPR00791 PEPDIPTASEA

Sequencei

Sequence statusi: Fragment.

Q7PM22-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRIFSTVIIA FALVCCVLGG KLVSVSDDEL EARRYVEQVD EEILSRRNVG
60 70 80 90 100
TEAEWAYESD INEDNLMVKN EVAAANAVFL KEVANTLNKY EYESFSDEDL
110 120 130 140 150
KRKIRKLTKL GYSVLPEDTF AEMLDAINRM QENYAKVKVC DYRDNSKCDL
160 170 180 190 200
ALEPELTEIM ATSRDPEELK YYWQQWYDAA GAPTRDDFQK YVDLNGVAAR
210 220 230 240 250
MNNYSSGAEY WLSAYEDDTF EEQVDAVIEE LRPLYEQIHA NVRYQLRKYY
260 270 280 290 300
GENVVSEKGP IPMHLLGNMW AQKWGNIADI TSPFPDRQLL DVTEEMVRQG
310 320 330 340 350
YNPIQMFEMG DKFFQSMNMT KLPATFWEKS ILEKPDDGRD LVCHASAWEF
360 370 380 390 400
SKTDDVRIKQ CTRVTMEQFF TVHHELGHVQ YFLQYQHLPS MYRDGANPGF
410 420 430 440 450
HEAVGDVLSL SVSTPKHLEK IGLLKDYVED EESKLNQFYG SALNKLVFLP
460 470 480 490 500
FAYTLDKYRW GIFRGDIKPE QYNCKFWEMR SKFSGVEPPV VRSESDLDAP
510 520 530 540 550
AKYHVSADVE YLRYFVSFII QFQFHRAACE KAGEYVKGDP EKTLNNCDIY
560 570 580 590 600
QSVEAGNAIK AMLELGSSKP WPDAMEVLTG ERRMSADALI EYFRPLYDWL
610 620 630
VVENERIGAH VGWENTTSKT ILNFSRVCIL LNE
Length:633
Mass (Da):73,274
Last modified:October 23, 2007 - v4
Checksum:i69E98C306929ACB5
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei633Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAAB01008980 Genomic DNA Translation: EAA14501.5
RefSeqiXP_318842.4, XM_318842.4

Genome annotation databases

EnsemblMetazoaiAGAP009756-RA; AGAP009756-PA; AGAP009756
GeneIDi1279162
KEGGiaga:AgaP_AGAP009756
VectorBaseiAGAP009756-RA; AGAP009756-PA; AGAP009756

Similar proteinsi

Entry informationi

Entry nameiQ7PM22_ANOGA
AccessioniPrimary (citable) accession number: Q7PM22
Entry historyiIntegrated into UniProtKB/TrEMBL: December 15, 2003
Last sequence update: October 23, 2007
Last modified: April 25, 2018
This is version 98 of the entry and version 4 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
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Main funding by: National Institutes of Health