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Q7PLK0 (Q7PLK0_DROME) Unreviewed, UniProtKB/TrEMBL

Last modified January 25, 2012. Version 58. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesSubmitted name:
Argonaute 3, isoform D EMBL ABI31274.2
Submitted name:
Argonaute 3, isoform E EMBL ABI31275.2
Submitted name:
Argonaute 3, isoform F EMBL EAA45981.3
Gene names
Name:AGO3 FlyBase FBgn0250816
ORF Names:Dmel_CG40300 EMBL EAA45981.3
OrganismDrosophila melanogaster (Fruit fly)
Taxonomic identifier7227 [NCBI]
Taxonomic lineageEukaryota › Metazoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora

Protein attributes

Sequence length867 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Sequence similarities

Contains 1 PAZ domain. SAAS SAAS003100

Contains 1 Piwi domain. SAAS SAAS003100

Ontologies

Keywords
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological processposttranscriptional gene silencing by RNA

Inferred from mutant phenotype. Source: FlyBase

   Cellular componentP granule

Inferred from direct assay. Source: FlyBase

   Molecular functionpiRNA binding

Inferred from direct assay. Source: FlyBase

Complete GO annotation...

Sequences

Sequence LengthMass (Da)Tools
Q7PLK0 [UniParc].

Last modified March 3, 2009. Version 3.
Checksum: AE613D6C845F78BE

FASTA86799,129
        10         20         30         40         50         60 
MSGRGNLLSL FNKNAGNMGK SISSKDHEID SGLDFNNSES SGERLLSSHN IETDLITTLQ 

        70         80         90        100        110        120 
HVNISVGRGR ARLIDTLKTD DHTSNQFITS ESKENITKKT KGPESEAIAS ENGLFFPDLI 

       130        140        150        160        170        180 
YGSKGSSVNI YCNYLKLTTD ESKGVFNYEV RFFPPIDSVH LRIKYLNDHK DKLGGTKTFD 

       190        200        210        220        230        240 
GNTLYLPILL PNKMTVFISK AEDVELQIRI LYKKKEEMRN CTQLYNILFD RVMKVLNYVK 

       250        260        270        280        290        300 
FDRKQFDPSR PKIIPLAKLE VWPGYVTAVD EYKGGLMLCC DVSHRILCQK TVLEMLVDLY 

       310        320        330        340        350        360 
QQNVEHYQES ARKMLVGNIV LTRYNNRTYK INDICFDQNP TCQFEIKTGC TSYVEYYKQY 

       370        380        390        400        410        420 
HNINIKDVNQ PLIYSIKKSR GIPAERENLQ FCLIPELCYL TGLRDEVRSD NKLMREIATF 

       430        440        450        460        470        480 
TRVSPNQRQM ALNKFYENVS NTPAAQEILN SWGLSLTNNS NKISGRQMDI EQIYFSKISV 

       490        500        510        520        530        540 
SAGRSAEFSK HAVTNEMLKV VHLSKWIIIH LRNYRQAATS LLDNMKQACE SLGMNISNPT 

       550        560        570        580        590        600 
MISLDHDRID AYIQALRRNI TMNTQMVVCI CHNRRDDRYA AIKKICCSEI PIPSQVINAK 

       610        620        630        640        650        660 
TLQNDLKIRS VVQKIVLQMN CKLGGSLWTV KIPFKNVMIC GIDSYHDPSN RGNSVAAFVA 

       670        680        690        700        710        720 
SINSSYSQWY SKAVVQTKRE EIVNGLSASF EIALKMYRKR NGKLPTNIII YRDGIGDGQL 

       730        740        750        760        770        780 
YTCLNYEIPQ FEMVCGNRIK ISYIVVQKRI NTRIFSGSGI HLENPLPGTV VDQHITKSNM 

       790        800        810        820        830        840 
YDFFLVSQLV RQGTVTPTHY VVLRDDCNYG PDIIQKLSYK LCFLYYNWAG TVRIPACCMY 

       850        860 
AHKLAYLIGQ SIQRDVAEAL SEKLFYL

« Hide

References

« Hide 'large scale' references
[1]"The genome sequence of Drosophila melanogaster."
Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D., Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F., George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N., Sutton G.G., Wortman J.R., Yandell M.D. expand/collapse author list , Zhang Q., Chen L.X., Brandon R.C., Rogers Y.H., Blazej R.G., Champe M., Pfeiffer B.D., Wan K.H., Doyle C., Baxter E.G., Helt G., Nelson C.R., Gabor G.L., Abril J.F., Agbayani A., An H.J., Andrews-Pfannkoch C., Baldwin D., Ballew R.M., Basu A., Baxendale J., Bayraktaroglu L., Beasley E.M., Beeson K.Y., Benos P.V., Berman B.P., Bhandari D., Bolshakov S., Borkova D., Botchan M.R., Bouck J., Brokstein P., Brottier P., Burtis K.C., Busam D.A., Butler H., Cadieu E., Center A., Chandra I., Cherry J.M., Cawley S., Dahlke C., Davenport L.B., Davies P., de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I., Dietz S.M., Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C., Dunn P., Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S., Fleischmann W., Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M., Glasser K., Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M., Harris N.L., Harvey D., Heiman T.J., Hernandez J.R., Houck J., Hostin D., Houston K.A., Howland T.J., Wei M.H., Ibegwam C., Jalali M., Kalush F., Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., Kimmel B.E., Kodira C.D., Kraft C., Kravitz S., Kulp D., Lai Z., Lasko P., Lei Y., Levitsky A.A., Li J., Li Z., Liang Y., Lin X., Liu X., Mattei B., McIntosh T.C., McLeod M.P., McPherson D., Merkulov G., Milshina N.V., Mobarry C., Morris J., Moshrefi A., Mount S.M., Moy M., Murphy B., Murphy L., Muzny D.M., Nelson D.L., Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R., Pacleb J.M., Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V., Reese M.G., Reinert K., Remington K., Saunders R.D., Scheeler F., Shen H., Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T., Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., Svirskas R., Tector C., Turner R., Venter E., Wang A.H., Wang X., Wang Z.Y., Wassarman D.A., Weinstock G.M., Weissenbach J., Williams S.M., WoodageT, Worley K.C., Wu D., Yang S., Yao Q.A., Ye J., Yeh R.F., Zaveri J.S., Zhan M., Zhang G., Zhao Q., Zheng L., Zheng X.H., Zhong F.N., Zhong W., Zhou X., Zhu S., Zhu X., Smith H.O., Gibbs R.A., Myers E.W., Rubin G.M., Venter J.C.
Science 287:2185-2195(2000) [PubMed: 10731132] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Berkeley.
[2]"Annotation of the Drosophila melanogaster euchromatic genome: a systematic review."
Misra S., Crosby M.A., Mungall C.J., Matthews B.B., Campbell K.S., Hradecky P., Huang Y., Kaminker J.S., Millburn G.H., Prochnik S.E., Smith C.D., Tupy J.L., Whitfield E.J., Bayraktaroglu L., Berman B.P., Bettencourt B.R., Celniker S.E., de Grey A.D.N.J. expand/collapse author list , Drysdale R.A., Harris N.L., Richter J., Russo S., Schroeder A.J., Shu S.Q., Stapleton M., Yamada C., Ashburner M., Gelbart W.M., Rubin G.M., Lewis S.E.
Genome Biol. 3:RESEARCH0083.1-RESEARCH0083.22(2002) [PubMed: 12537572] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: Berkeley.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AE014296 Genomic DNA. Translation: ABI31274.2.
AE014296 Genomic DNA. Translation: ABI31275.2.
AE014296 Genomic DNA. Translation: EAA45981.3.
RefSeqNP_001036627.2. NM_001043162.2.
NP_001036628.2. NM_001043163.2.
NP_001036629.2. NM_001043164.2.
UniGeneDm.33791.

3D structure databases

ProteinModelPortalQ7PLK0.
SMRQ7PLK0. Positions 289-401.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ7PLK0.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaFBtr0299880; FBpp0289158; FBgn0250816.
FBtr0299881; FBpp0289159; FBgn0250816.
FBtr0299882; FBpp0289160; FBgn0250816.
GeneID3355150.
KEGGdme:Dmel_CG40300.

Organism-specific databases

CTD3355150.
FlyBaseFBgn0250816. AGO3.

Phylogenomic databases

eggNOGinNOG04337.
GeneTreeEMGT00070000025681.
InParanoidQ7PLK0.
OrthoDBEOG49GHXN.
PhylomeDBQ7PLK0.

Gene expression databases

ArrayExpressQ7PLK0.
BgeeQ7PLK0.

Family and domain databases

InterProIPR003100. PAZ.
IPR003165. Piwi.
IPR012337. RNaseH-like_dom.
[Graphical view]
KOK02156.
PfamPF02170. PAZ. 1 hit.
PF02171. Piwi. 1 hit.
[Graphical view]
SMARTSM00949. PAZ. 1 hit.
SM00950. Piwi. 1 hit.
[Graphical view]
SUPFAMSSF101690. PAZ. 1 hit.
SSF53098. RNaseH_fold. 1 hit.
PROSITEPS50821. PAZ. 1 hit.
PS50822. PIWI. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio850876.

Entry information

Entry nameQ7PLK0_DROME
AccessionPrimary (citable) accession number: Q7PLK0
Entry history
Integrated into UniProtKB/TrEMBL: December 15, 2003
Last sequence update: March 3, 2009
Last modified: January 25, 2012
This is version 58 of the entry and version 3 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry info