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Protein
Submitted name:

AGAP005221-PA

Gene

1274929

Organism
Anopheles gambiae (African malaria mosquito)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei475S-adenosyl-L-methioninePROSITE-ProRule annotation1
Binding sitei502S-adenosyl-L-methioninePROSITE-ProRule annotation1
Binding sitei519S-adenosyl-L-methioninePROSITE-ProRule annotation1
Active sitei576NucleophilePROSITE-ProRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionMethyltransferasePROSITE-ProRule annotation, RNA-bindingPROSITE-ProRule annotation, Transferase
LigandS-adenosyl-L-methioninePROSITE-ProRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
AGAP005221-PAImported
Submitted name:
Ribosomal RNA methyltransferase Nop2Imported
Gene namesi
Name:1274929Imported
ORF Names:AgaP_AGAP005221Imported
OrganismiAnopheles gambiae (African malaria mosquito)Imported
Taxonomic identifieri7165 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraNematoceraCulicoideaCulicidaeAnophelinaeAnopheles
Proteomesi
  • UP000007062 Componenti: Chromosome 2L

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Interactioni

Protein-protein interaction databases

STRINGi7165.AGAP005221-PA

Structurei

3D structure databases

ProteinModelPortaliQ7PHH2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini359 – 646SAM_MT_RSMB_NOPInterPro annotationAdd BLAST288

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni451 – 457S-adenosyl-L-methionine bindingPROSITE-ProRule annotation7

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili50 – 70Sequence analysisAdd BLAST21
Coiled coili158 – 197Sequence analysisAdd BLAST40
Coiled coili253 – 277Sequence analysisAdd BLAST25
Coiled coili764 – 787Sequence analysisAdd BLAST24

Sequence similaritiesi

Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.PROSITE-ProRule annotation

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG1122 Eukaryota
COG0144 LUCA
HOGENOMiHOG000224258
InParanoidiQ7PHH2
KOiK14835
OMAiDVQRCYN
OrthoDBiEOG091G0685
PhylomeDBiQ7PHH2

Family and domain databases

InterProiView protein in InterPro
IPR018314 Fmu/NOL1/Nop2p_CS
IPR031341 Methyltr_RsmF_N
IPR001678 MeTrfase_RsmB/NOP2
IPR011023 Nop2p
IPR023267 RCMT
IPR023273 RCMT_NOP2
IPR029063 SAM-dependent_MTases
PfamiView protein in Pfam
PF01189 Methyltr_RsmB-F, 1 hit
PF17125 Methyltr_RsmF_N, 1 hit
PRINTSiPR02008 RCMTFAMILY
PR02012 RCMTNOP2
SUPFAMiSSF53335 SSF53335, 1 hit
TIGRFAMsiTIGR00446 nop2p, 1 hit
PROSITEiView protein in PROSITE
PS01153 NOL1_NOP2_SUN, 1 hit
PS51686 SAM_MT_RSMB_NOP, 1 hit

Sequencei

Sequence statusi: Complete.

Q7PHH2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGRKINLERP KKGPGRKARK QPEPEFQFKK GEDEDSNKKL SRHQIQRLKK
60 70 80 90 100
REMLKQKQKE EKKTKKATKN AAKVAAVPNT FDPAEIFNIE KSRQKYQQLG
110 120 130 140 150
QKSKTPQPVA TNGHQNGSAK KGRNLFDSDN EMDEDEQKAA TGKKVQVKKS
160 170 180 190 200
QMKKFLQRAE SEDESDSEEE EMDSDVEEEE DEEAESVEGE EDDYEDEDVG
210 220 230 240 250
EELDDEEEND EMGAEEDYED DDEDDEDDED EEDEDDDDED DEDGDMLPIE
260 270 280 290 300
AANKKLKKRM EREQKEADAE MAEAAVNRER FAFPTEEELA QTTSLQDVNM
310 320 330 340 350
RIKDVVGVLS DFAANRDPNR SRCEYIDLLR RDLCLYYSYN DFFMGLLMEI
360 370 380 390 400
FSPNELLEFL EASEIQRPVT IRTNSLKTRR RDLAQALINR GINLDPIGKW
410 420 430 440 450
SKEGLVVYTS QVPLGATPEY LAGHYMLQGG SSMLPVMALA PEENERILDM
460 470 480 490 500
CAAPGGKSSH IAALMKNTGV LFVNDANKER LHAVLGNFHR LGIQNAVITC
510 520 530 540 550
MDGVKYGNIM KGFDRVLLDA PCTGSGVISK DPSVKATKNE IDVQRCFNLQ
560 570 580 590 600
RRLLLTAIDC LSASSPTGGY LVYSTCSILP QENEWVIDFA LKRRNVRLVP
610 620 630 640 650
TGLDFGVEGM TNFGAHRFHP TMKLTRRFYP HTHNLDGFFV AKLQKFSDAI
660 670 680 690 700
PKSVDGEPEA EDEVEEEPEE EMKLPKKIDK RDWYYQDIID ERKAQREDKN
710 720 730 740 750
KNHVVTVFQK PANVKKGPKK PKQPQPSAGE REQKPQKPAS EEPKQPATNG
760 770 780 790 800
TSSSSKQRQP APKSNTEQRE AEEALRLKKK LKQVQTKNGK AGPGGKKNGE
810 820
KKKVVQGVKK GAFKSKVGKM RTAK
Length:824
Mass (Da):93,355
Last modified:October 23, 2007 - v4
Checksum:i4A2C82DEBACC5110
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAAB01008900 Genomic DNA Translation: EAA44543.4
RefSeqiXP_314123.4, XM_314123.4

Genome annotation databases

EnsemblMetazoaiAGAP005221-RA; AGAP005221-PA; AGAP005221
GeneIDi1274929
KEGGiaga:AgaP_AGAP005221
VectorBaseiAGAP005221-RA; AGAP005221-PA; AGAP005221

Similar proteinsi

Entry informationi

Entry nameiQ7PHH2_ANOGA
AccessioniPrimary (citable) accession number: Q7PHH2
Entry historyiIntegrated into UniProtKB/TrEMBL: December 15, 2003
Last sequence update: October 23, 2007
Last modified: May 23, 2018
This is version 85 of the entry and version 4 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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