Reviewed, UniProtKB/Swiss-Prot Q7P1R4 (G6PI1_CHRVO)

Names and origin

Protein names

Recommended name:
    Glucose-6-phosphate isomerase 1
      Short name=GPI 1
    EC=5.3.1.9
Alternative name(s):
    Phosphoglucose isomerase 1
      Short name=PGI 1
    Phosphohexose isomerase 1
      Short name=PHI 1

Gene names

Name:	pgi1
Ordered Locus Names:	CV_0149

Organism

Chromobacterium violaceum [Complete proteome] [HAMAP]

Taxonomic identifier

536 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Betaproteobacteria › Neisseriales › Neisseriaceae › Chromobacterium

Protein attributes

Sequence length	547 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	D-glucose 6-phosphate = D-fructose 6-phosphate. HAMAP MF_00473
Pathway	Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 2/4. HAMAP MF_00473
Subcellular location	Cytoplasm By similarity.
Sequence similarities	Belongs to the GPI family.

Ontologies

Keywords
Biological process	Gluconeogenesis Glycolysis
Cellular component	Cytoplasm
Molecular function	Isomerase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	gluconeogenesis Inferred from electronic annotation. Source: HAMAP glycolysis Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	glucose-6-phosphate isomerase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 547	547	Glucose-6-phosphate isomerase 1 HAMAP MF_00473		PRO_0000180624
Sites
	Active site	353	1	Proton donor By similarity
	Active site	384	1	By similarity
	Active site	512	1	By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q7P1R4-1 [UniParc]. Last modified December 15, 2003. Version 1. Checksum: F264B1BFD1E23DB7	FASTA	547	61,073
	10 20 30 40 50 60 MSELTELPAW QALWDHFAEA KHLHMRDLFA ADPGRAERYS LEVGGLFLDY SKNRITDATL 70 80 90 100 110 120 LGLMELAREA GLPARIKAMF KGEKINRTEN RAVLHVALRN RTNSPIRVDG EDVMPKVNSV 130 140 150 160 170 180 LERMGKFAHA VRSGDWLGFT NQPITDIVNI GIGGSDLGPL MVCSALKPFG HPRLNMHFVS 190 200 210 220 230 240 NVDGAQLKET LKKVHPETTL FVVESKTFTT QETLTNALTA REWFLSHARD EGAVAKHFVA 250 260 270 280 290 300 VSTNQKAVAE FGIDPANMFE FWNWVGGRYS LWSAIGLPIM LYLGEENFTE LLNGAHIMDQ 310 320 330 340 350 360 HFMNAPFEQN MPVLLAMIGV WYINYYGGGS HVIAPYDQYL HRLPAFIQQL DMESNGKQVT 370 380 390 400 410 420 LSGQPVDFET APIIWGETGI NGQHAFFQLL HQGTHISPID LIASLGNRAS LPGHHEILLA 430 440 450 460 470 480 NVFAQAEAFM RGKTADEVRA ELAEQGLSGE EMEALVPHKV FGGNRPTNTL LMSRLDPRNL 490 500 510 520 530 540 GSLIALYEHK IFVQGVIWHI NSFDQWGVEL GKQLAKTIHA ELTGKLEQAE HDSSTRRLIQ LYRKANG

References

[1]

"The complete genome sequence of Chromobacterium violaceum reveals remarkable and exploitable bacterial adaptability." Vasconcelos A.T.R., de Almeida D.F., Hungria M., Guimaraes C.T., Antonio R.V., Almeida F.C., de Almeida L.G.P., de Almeida R., Alves-Gomes J.A., Andrade E.M., Araripe J., de Araujo M.F.F., Astolfi-Filho S., Azevedo V., Baptista A.J., Bataus L.A.M., Batista J.S., Belo A. , van den Berg C., Bogo M., Bonatto S., Bordignon J., Brigido M.M., Brito C.A., Brocchi M., Burity H.A., Camargo A.A., Cardoso D.D.P., Carneiro N.P., Carraro D.M., Carvalho C.M.B., Cascardo J.C.M., Cavada B.S., Chueire L.M.O., Creczynski-Pasa T.B., Cunha-Junior N.C., Fagundes N., Falcao C.L., Fantinatti F., Farias I.P., Felipe M.S.S., Ferrari L.P., Ferro J.A., Ferro M.I.T., Franco G.R., Freitas N.S.A., Furlan L.R., Gazzinelli R.T., Gomes E.A., Goncalves P.R., Grangeiro T.B., Grattapaglia D., Grisard E.C., Hanna E.S., Jardim S.N., Laurino J., Leoi L.C.T., Lima L.F.A., Loureiro M.F., Lyra M.C.C.P., Madeira H.M.F., Manfio G.P., Maranhao A.Q., Martins W.S., di Mauro S.M.Z., de Medeiros S.R.B., Meissner R.V., Moreira M.A.M., Nascimento F.F., Nicolas M.F., Oliveira J.G., Oliveira S.C., Paixao R.F.C., Parente J.A., Pedrosa F.O., Pena S.D.J., Pereira J.O., Pereira M., Pinto L.S.R.C., Pinto L.S., Porto J.I.R., Potrich D.P., Ramalho-Neto C.E., Reis A.M.M., Rigo L.U., Rondinelli E., Santos E.B.P., Santos F.R., Schneider M.P.C., Seuanez H.N., Silva A.M.R., da Silva A.L.C., Silva D.W., Silva R., Simoes I.C., Simon D., Soares C.M.A., Soares R.B.A., Souza E.M., Souza K.R.L., Souza R.C., Steffens M.B.R., Steindel M., Teixeira S.R., Urmenyi T., Vettore A., Wassem R., Zaha A., Simpson A.J.G. Proc. Natl. Acad. Sci. U.S.A. 100:11660-11665(2003) [PubMed: 14500782] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 12472 / DSM 30191 / IFO 12614 / JCM 1249 / NCIB 9131.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AE016825 Genomic DNA. Translation: AAQ57828.1.
RefSeq	NP_899819.1.
3D structure databases
HSSP	HSSP built from PDB template 1JIQ based on UniProtKB P06744.
ModBase	Search...
Genome annotation databases
GeneID	2550708.
GenomeReviews	Gene locus CV_0149 in contig AE016825_GR.
KEGG	cvi:CV_0149.
NMPDR	fig|243365.1.peg.149.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q7P1R4.
OMA	GPKIVSQ.
Enzyme and pathway databases
BioCyc	CVIO243365:CV_0149-MON.
BRENDA	5.3.1.9. 415.
Family and domain databases
HAMAP	MF_00473. [Tree]
InterPro	IPR001672. G6P_Isomerase. IPR018189. Phosphoglucose_isomerase_CS. [Graphical view]
PANTHER	PTHR11469. G6P_Isomerase. 1 hit.
Pfam	PF00342. PGI. 1 hit. [Graphical view]
PRINTS	PR00662. G6PISOMERASE.
PROSITE	PS00765. P_GLUCOSE_ISOMERASE_1. 1 hit. PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit. PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

G6PI1_CHRVO

Accession

Primary (citable) accession number: Q7P1R4

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 8, 2005
Last sequence update:	December 15, 2003
Last modified:	November 3, 2009
This is version 42 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)