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Protein

Ribosomal silencing factor RsfS

Gene

rsfS

Organism
Chromobacterium violaceum (strain ATCC 12472 / DSM 30191 / JCM 1249 / NBRC 12614 / NCIMB 9131 / NCTC 9757)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.UniRule annotation

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Repressor

Keywords - Biological processi

Translation regulation

Enzyme and pathway databases

BioCyciCVIO243365:GHUD-528-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Ribosomal silencing factor RsfSUniRule annotation
Gene namesi
Name:rsfSUniRule annotation
Ordered Locus Names:CV_0518
OrganismiChromobacterium violaceum (strain ATCC 12472 / DSM 30191 / JCM 1249 / NBRC 12614 / NCIMB 9131 / NCTC 9757)
Taxonomic identifieri243365 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaNeisserialesChromobacteriaceaeChromobacterium
Proteomesi
  • UP000001424 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 122122Ribosomal silencing factor RsfSPRO_0000419624Add
BLAST

Interactioni

Subunit structurei

Interacts with ribosomal protein L14 (rplN).UniRule annotation

Protein-protein interaction databases

STRINGi243365.CV_0518.

Structurei

Secondary structure

1
122
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Helixi3 – 1614Combined sources
Beta strandi20 – 267Combined sources
Helixi27 – 293Combined sources
Beta strandi35 – 417Combined sources
Helixi45 – 6117Combined sources
Turni72 – 743Combined sources
Beta strandi75 – 828Combined sources
Beta strandi85 – 906Combined sources
Helixi92 – 987Combined sources
Helixi100 – 1034Combined sources

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
2ID1X-ray3.00A/B1-122[»]
ProteinModelPortaliQ7P0P8.
SMRiQ7P0P8. Positions 1-120.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ7P0P8.

Family & Domainsi

Sequence similaritiesi

Belongs to the Iojap/RsfS family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105KEM. Bacteria.
COG0799. LUCA.
HOGENOMiHOG000016051.
KOiK09710.
OMAiEHLWEDA.
OrthoDBiPOG091H008J.

Family and domain databases

HAMAPiMF_01477. Iojap_RsfS. 1 hit.
InterProiIPR004394. Iojap/RsfS/C7orf30.
[Graphical view]
PANTHERiPTHR21043. PTHR21043. 1 hit.
TIGRFAMsiTIGR00090. rsfS_iojap_ybeB. 1 hit.

Sequencei

Sequence statusi: Complete.

Q7P0P8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEIQEISKLA IEALEDIKGK DIIELDTSKL TSLFQRMIVA TGDSNRQVKA
60 70 80 90 100
LANSVQVKLK EAGVDIVGSE GHESGEWVLV DAGDVVVHVM LPAVRDYYDI
110 120
EALWGGQKPS FAVGAAKPWS AV
Length:122
Mass (Da):13,193
Last modified:December 15, 2003 - v1
Checksum:i80EDD9D5B220E909
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE016825 Genomic DNA. Translation: AAQ58195.1.
RefSeqiWP_011134073.1. NC_005085.1.

Genome annotation databases

EnsemblBacteriaiAAQ58195; AAQ58195; CV_0518.
GeneIDi24946262.
KEGGicvi:CV_0518.
PATRICi21435832. VBIChrVio67196_0517.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE016825 Genomic DNA. Translation: AAQ58195.1.
RefSeqiWP_011134073.1. NC_005085.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
2ID1X-ray3.00A/B1-122[»]
ProteinModelPortaliQ7P0P8.
SMRiQ7P0P8. Positions 1-120.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi243365.CV_0518.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAQ58195; AAQ58195; CV_0518.
GeneIDi24946262.
KEGGicvi:CV_0518.
PATRICi21435832. VBIChrVio67196_0517.

Phylogenomic databases

eggNOGiENOG4105KEM. Bacteria.
COG0799. LUCA.
HOGENOMiHOG000016051.
KOiK09710.
OMAiEHLWEDA.
OrthoDBiPOG091H008J.

Enzyme and pathway databases

BioCyciCVIO243365:GHUD-528-MONOMER.

Miscellaneous databases

EvolutionaryTraceiQ7P0P8.

Family and domain databases

HAMAPiMF_01477. Iojap_RsfS. 1 hit.
InterProiIPR004394. Iojap/RsfS/C7orf30.
[Graphical view]
PANTHERiPTHR21043. PTHR21043. 1 hit.
TIGRFAMsiTIGR00090. rsfS_iojap_ybeB. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiIOJAP_CHRVO
AccessioniPrimary (citable) accession number: Q7P0P8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 3, 2012
Last sequence update: December 15, 2003
Last modified: September 7, 2016
This is version 76 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.