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Q7P0F3

- HIS7_CHRVO

UniProt

Q7P0F3 - HIS7_CHRVO

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Protein

Imidazoleglycerol-phosphate dehydratase

Gene
hisB, CV_0614
Organism
Chromobacterium violaceum (strain ATCC 12472 / DSM 30191 / JCM 1249 / NBRC 12614 / NCIMB 9131 / NCTC 9757)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate = 3-(imidazol-4-yl)-2-oxopropyl phosphate + H2O.UniRule annotation

Pathwayi

GO - Molecular functioni

  1. imidazoleglycerol-phosphate dehydratase activity Source: UniProtKB-EC

GO - Biological processi

  1. histidine biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Lyase

Keywords - Biological processi

Amino-acid biosynthesis, Histidine biosynthesis

Enzyme and pathway databases

BioCyciCVIO243365:GHUD-624-MONOMER.
UniPathwayiUPA00031; UER00011.

Names & Taxonomyi

Protein namesi
Recommended name:
Imidazoleglycerol-phosphate dehydratase (EC:4.2.1.19)
Short name:
IGPD
Gene namesi
Name:hisB
Ordered Locus Names:CV_0614
OrganismiChromobacterium violaceum (strain ATCC 12472 / DSM 30191 / JCM 1249 / NBRC 12614 / NCIMB 9131 / NCTC 9757)
Taxonomic identifieri243365 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaNeisserialesChromobacteriaceaeChromobacterium
ProteomesiUP000001424: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 197197Imidazoleglycerol-phosphate dehydrataseUniRule annotationPRO_0000158123Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi243365.CV_0614.

Structurei

3D structure databases

ProteinModelPortaliQ7P0F3.
SMRiQ7P0F3. Positions 2-183.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0131.
HOGENOMiHOG000228064.
KOiK01693.
OMAiHHIAESC.
OrthoDBiEOG60PHGP.

Family and domain databases

HAMAPiMF_00076. HisB.
InterProiIPR000807. ImidazoleglycerolP_deHydtase.
IPR020565. ImidazoleglycerP_deHydtase_CS.
IPR020568. Ribosomal_S5_D2-typ_fold.
[Graphical view]
PANTHERiPTHR23133:SF2. PTHR23133:SF2. 1 hit.
PfamiPF00475. IGPD. 1 hit.
[Graphical view]
SUPFAMiSSF54211. SSF54211. 2 hits.
PROSITEiPS00954. IGP_DEHYDRATASE_1. 1 hit.
PS00955. IGP_DEHYDRATASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q7P0F3-1 [UniParc]FASTAAdd to Basket

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MRTATVTRNT LETQITVSLN LDGTGVGRFE TGVPFLDHMM DQIARHGLID    50
LDVKAVGDLH IDAHHTVEDI GITLGQAFAK AIGDKKGIRR YGHAYVPLDE 100
ALSRVVIDLS GRPGLVYNVD YTRACIGQFD VDLFSEFFHG FVNHSMVTLH 150
IDNLRGHNSH HQAETIFKAF GRALRMACEH DERMAGITPS TKGTLSV 197
Length:197
Mass (Da):21,752
Last modified:December 15, 2003 - v1
Checksum:iAE696FF868135312
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE016825 Genomic DNA. Translation: AAQ58290.1.
RefSeqiNP_900284.1. NC_005085.1.
WP_011134169.1. NC_005085.1.

Genome annotation databases

EnsemblBacteriaiAAQ58290; AAQ58290; CV_0614.
GeneIDi2548395.
KEGGicvi:CV_0614.
PATRICi21436024. VBIChrVio67196_0613.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE016825 Genomic DNA. Translation: AAQ58290.1 .
RefSeqi NP_900284.1. NC_005085.1.
WP_011134169.1. NC_005085.1.

3D structure databases

ProteinModelPortali Q7P0F3.
SMRi Q7P0F3. Positions 2-183.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 243365.CV_0614.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAQ58290 ; AAQ58290 ; CV_0614 .
GeneIDi 2548395.
KEGGi cvi:CV_0614.
PATRICi 21436024. VBIChrVio67196_0613.

Phylogenomic databases

eggNOGi COG0131.
HOGENOMi HOG000228064.
KOi K01693.
OMAi HHIAESC.
OrthoDBi EOG60PHGP.

Enzyme and pathway databases

UniPathwayi UPA00031 ; UER00011 .
BioCyci CVIO243365:GHUD-624-MONOMER.

Family and domain databases

HAMAPi MF_00076. HisB.
InterProi IPR000807. ImidazoleglycerolP_deHydtase.
IPR020565. ImidazoleglycerP_deHydtase_CS.
IPR020568. Ribosomal_S5_D2-typ_fold.
[Graphical view ]
PANTHERi PTHR23133:SF2. PTHR23133:SF2. 1 hit.
Pfami PF00475. IGPD. 1 hit.
[Graphical view ]
SUPFAMi SSF54211. SSF54211. 2 hits.
PROSITEi PS00954. IGP_DEHYDRATASE_1. 1 hit.
PS00955. IGP_DEHYDRATASE_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "The complete genome sequence of Chromobacterium violaceum reveals remarkable and exploitable bacterial adaptability."
    Vasconcelos A.T.R., de Almeida D.F., Hungria M., Guimaraes C.T., Antonio R.V., Almeida F.C., de Almeida L.G.P., de Almeida R., Alves-Gomes J.A., Andrade E.M., Araripe J., de Araujo M.F.F., Astolfi-Filho S., Azevedo V., Baptista A.J., Bataus L.A.M., Batista J.S., Belo A.
    , van den Berg C., Bogo M., Bonatto S., Bordignon J., Brigido M.M., Brito C.A., Brocchi M., Burity H.A., Camargo A.A., Cardoso D.D.P., Carneiro N.P., Carraro D.M., Carvalho C.M.B., Cascardo J.C.M., Cavada B.S., Chueire L.M.O., Creczynski-Pasa T.B., Cunha-Junior N.C., Fagundes N., Falcao C.L., Fantinatti F., Farias I.P., Felipe M.S.S., Ferrari L.P., Ferro J.A., Ferro M.I.T., Franco G.R., Freitas N.S.A., Furlan L.R., Gazzinelli R.T., Gomes E.A., Goncalves P.R., Grangeiro T.B., Grattapaglia D., Grisard E.C., Hanna E.S., Jardim S.N., Laurino J., Leoi L.C.T., Lima L.F.A., Loureiro M.F., Lyra M.C.C.P., Madeira H.M.F., Manfio G.P., Maranhao A.Q., Martins W.S., di Mauro S.M.Z., de Medeiros S.R.B., Meissner R.V., Moreira M.A.M., Nascimento F.F., Nicolas M.F., Oliveira J.G., Oliveira S.C., Paixao R.F.C., Parente J.A., Pedrosa F.O., Pena S.D.J., Pereira J.O., Pereira M., Pinto L.S.R.C., Pinto L.S., Porto J.I.R., Potrich D.P., Ramalho-Neto C.E., Reis A.M.M., Rigo L.U., Rondinelli E., Santos E.B.P., Santos F.R., Schneider M.P.C., Seuanez H.N., Silva A.M.R., da Silva A.L.C., Silva D.W., Silva R., Simoes I.C., Simon D., Soares C.M.A., Soares R.B.A., Souza E.M., Souza K.R.L., Souza R.C., Steffens M.B.R., Steindel M., Teixeira S.R., Urmenyi T., Vettore A., Wassem R., Zaha A., Simpson A.J.G.
    Proc. Natl. Acad. Sci. U.S.A. 100:11660-11665(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 12472 / DSM 30191 / JCM 1249 / NBRC 12614 / NCIMB 9131 / NCTC 9757.

Entry informationi

Entry nameiHIS7_CHRVO
AccessioniPrimary (citable) accession number: Q7P0F3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 1, 2004
Last sequence update: December 15, 2003
Last modified: September 3, 2014
This is version 77 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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