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Protein

Glutamine--tRNA ligase

Gene

glnS

Organism
Chromobacterium violaceum (strain ATCC 12472 / DSM 30191 / JCM 1249 / NBRC 12614 / NCIMB 9131 / NCTC 9757)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-glutamine + tRNA(Gln) = AMP + diphosphate + L-glutaminyl-tRNA(Gln).UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei69L-glutamineUniRule annotation1
Binding sitei214L-glutamineUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi37 – 39ATPUniRule annotation3
Nucleotide bindingi43 – 49ATPUniRule annotation7
Nucleotide bindingi263 – 264ATPUniRule annotation2

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminoacyl-tRNA synthetase, Ligase
Biological processProtein biosynthesis
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamine--tRNA ligaseUniRule annotation (EC:6.1.1.18UniRule annotation)
Alternative name(s):
Glutaminyl-tRNA synthetaseUniRule annotation
Short name:
GlnRSUniRule annotation
Gene namesi
Name:glnSUniRule annotation
Ordered Locus Names:CV_1742
OrganismiChromobacterium violaceum (strain ATCC 12472 / DSM 30191 / JCM 1249 / NBRC 12614 / NCIMB 9131 / NCTC 9757)
Taxonomic identifieri243365 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaNeisserialesChromobacteriaceaeChromobacterium
Proteomesi
  • UP000001424 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001958301 – 560Glutamine--tRNA ligaseAdd BLAST560

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi243365.CV_1742.

Structurei

3D structure databases

ProteinModelPortaliQ7NX86.
SMRiQ7NX86.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi36 – 46"HIGH" regionUniRule annotationAdd BLAST11
Motifi270 – 274"KMSKS" regionUniRule annotation5

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CX6. Bacteria.
COG0008. LUCA.
HOGENOMiHOG000259232.
KOiK01886.
OMAiVTHSICT.
OrthoDBiPOG091H00G9.

Family and domain databases

Gene3Di1.10.1160.10. 1 hit.
2.40.240.10. 2 hits.
3.40.50.620. 2 hits.
HAMAPiMF_00126. Gln_tRNA_synth. 1 hit.
InterProiView protein in InterPro
IPR004514. Gln-tRNA-synth.
IPR022861. Gln_tRNA_ligase_bac.
IPR000924. Glu/Gln-tRNA-synth.
IPR020061. Glu/Gln-tRNA-synth_Ib_a-bdl.
IPR020058. Glu/Gln-tRNA-synth_Ib_cat-dom.
IPR020059. Glu/Gln-tRNA-synth_Ib_codon-bd.
IPR020056. Rbsml_L25/Gln-tRNA_synth_b-brl.
IPR011035. Ribosomal_L25/Gln-tRNA_synth.
IPR014729. Rossmann-like_a/b/a_fold.
PfamiView protein in Pfam
PF00749. tRNA-synt_1c. 1 hit.
PF03950. tRNA-synt_1c_C. 1 hit.
PRINTSiPR00987. TRNASYNTHGLU.
SUPFAMiSSF50715. SSF50715. 1 hit.
TIGRFAMsiTIGR00440. glnS. 1 hit.

Sequencei

Sequence statusi: Complete.

Q7NX86-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSTENNAPVV NNFIRSIIDE DLATGRRSSV VTRFPPEPNG FAHIGHAKAI
60 70 80 90 100
CINFGLAEDY NGQCNLRMDD TNPEKESDEF VEAFKQDISW LGFKWNGEVR
110 120 130 140 150
YASDYFDRLY DYAVELIQAG KAYVDDLSAE EMRQYRGNLT EPGKNSPYRD
160 170 180 190 200
RTPEENLDLF TRMKNGEFPD GSKTLRLKID MASGNINLRD PAIYRIRRVH
210 220 230 240 250
HHRTGDKWCI YPMYDYTHCI SDAIEGITHS LCSLEFEDHR PLYDWVLDNI
260 270 280 290 300
SIEHHPQQIE FSRLELLYAL TSKRKLQALV NDGAVTGWDD PRMPTIAGMR
310 320 330 340 350
RRGYSPAGIK LFAQRIGVSK SENIIDMAIL EGAVRETLEN DSPRVMAVVN
360 370 380 390 400
PLKVTLTNYD AAVTASRSAP FHPHHPEFGE RDVPIAREIW IERDDFAETP
410 420 430 440 450
PPKWQRLTAG GEVRLRYSYV IKCDEVVKDA ADEIVELKCS IDHDTLGKNP
460 470 480 490 500
EGRKVKGVIH WVSAEHAIQA DVRWYERLFT EQRPDAVRGE DGEYVDFRQF
510 520 530 540 550
LNPESLKLVP AYVEASVLQA EPESRFQFER LGYFVTDRYE HRKGDKAVFN
560
RTVGLKDSWK
Length:560
Mass (Da):64,372
Last modified:December 15, 2003 - v1
Checksum:i2E23F03ECAB9CEF5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE016825 Genomic DNA. Translation: AAQ59416.2.
RefSeqiWP_011135294.1. NC_005085.1.

Genome annotation databases

EnsemblBacteriaiAAQ59416; AAQ59416; CV_1742.
GeneIDi24946675.
KEGGicvi:CV_1742.

Similar proteinsi

Entry informationi

Entry nameiSYQ_CHRVO
AccessioniPrimary (citable) accession number: Q7NX86
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 26, 2004
Last sequence update: December 15, 2003
Last modified: August 30, 2017
This is version 96 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Aminoacyl-tRNA synthetases
    List of aminoacyl-tRNA synthetase entries
  2. SIMILARITY comments
    Index of protein domains and families