Reviewed, UniProtKB/Swiss-Prot Q7NW95 (GLNE_CHRVO)

Names and origin

Protein names

Recommended name:
    Glutamate-ammonia-ligase adenylyltransferase
    EC=2.7.7.42
Alternative name(s):
    [Glutamate--ammonia-ligase] adenylyltransferase
    Glutamine-synthetase adenylyltransferase
      Short name=ATase

Gene names

Name:	glnE
Ordered Locus Names:	CV_2095

Organism

Chromobacterium violaceum [Complete proteome] [HAMAP]

Taxonomic identifier

536 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Betaproteobacteria › Neisseriales › Neisseriaceae › Chromobacterium

Protein attributes

Sequence length	894 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Adenylation and deadenylation of glutamine synthetase By similarity.
Catalytic activity	ATP + [L-glutamate:ammonia ligase (ADP-forming)] = diphosphate + adenylyl-[L-glutamate:ammonia ligase (ADP-forming)]. HAMAP MF_00802
Sequence similarities	Belongs to the glnE family.

Ontologies

Keywords
Domain	Repeat
Ligand	ATP-binding Nucleotide-binding
Molecular function	Nucleotidyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW [glutamate-ammonia-ligase] adenylyltransferase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 894	894	Glutamate-ammonia-ligase adenylyltransferase HAMAP MF_00802		PRO_0000209240
Regions
	Region	66 – 272	207	GlnE 1 HAMAP MF_00802
	Region	573 – 777	205	GlnE 2 HAMAP MF_00802

Sequences

	Sequence		Length	Mass (Da)
	Q7NW95-1 [UniParc]. Last modified December 15, 2003. Version 1. Checksum: 1D3D48813A4ABC2C	FASTA	894	99,843
	10 20 30 40 50 60 MPANTSAAIA RSCEFSQYLH RLLTARPEER QRLEQSLHHP FSLEDMQAFA DWPALDAPEA 70 80 90 100 110 120 LAPALRRLRQ AVVARLICRD LESLATLDEV VSTISQLAEF AVRQALACAA ASLPQYGRPI 130 140 150 160 170 180 GEDSGEPQQL IVIGMGKLGG GELNVSSDID LIFIYPEGGE TDGARKISNH EYFTQVGKRL 190 200 210 220 230 240 IALLNDATAD GQVFRVDMRL RPYGDSGPLV MSFAALENYL LSQGREWERY AWIKAKAITG 250 260 270 280 290 300 DADGLAQLVR PFVYRKYLDY NAYGAMRGLH AQIRREVARR DMADNIKLGP GGIREAEFIA 310 320 330 340 350 360 QVFQLIRGGR DRTLQLRGTR ATLERLAALR LLEPAAVAEL QASYAFLRNL EHRLQYLDDQ 370 380 390 400 410 420 QTQTLPEAPE TRQKIAASMG HADWPAFLDA LNEVRRKVSR HFEQVFILPS EDSASHPLSE 430 440 450 460 470 480 LWLDVAEQSP ETRLAELGYA DPAAVARQLT GLAQSQRYLQ MPLAGRKQLD ALMPALIEVA 490 500 510 520 530 540 ARFPNADDTL SRIIGLMEAI SRRASYLALL TEYPQTLQRL ASLYSSSAWV SAYLSRHPIL 550 560 570 580 590 600 LDELLDARML YAAPDWPLLA AQLETQLAQA DGDVEAKMDA LRHFQHAQTF RLVAQDLAGM 610 620 630 640 650 660 WTLEALSDEL SRLADLVLAA AVRHAWRDIP SRHCETPRFA VIGYGKLGGK ELGYASDLDI 670 680 690 700 710 720 IFLYDDEHPD APDLYSRLAR KLSTWLTSAT AAGVLYDIDL RLRPNGSSGL LVSSISAFRQ 730 740 750 760 770 780 YQENQAWVWE HQALTRARFV AGDAGIGSQF EAERHAILTL ERDPAKLRDE VMAMRQRMLD 790 800 810 820 830 840 SHPAHDGDVK NARGGIIDIE FIVQYLILAH AKTLPALTGN TGNIALLAVA AEAGLIDRRL 850 860 870 880 890 AEDARAAYRL YRRLQHSARL NDRKTVEVDE SLRTAYARGR ELWRQVFEQA LDFS

References

[1]

"The complete genome sequence of Chromobacterium violaceum reveals remarkable and exploitable bacterial adaptability." Vasconcelos A.T.R., de Almeida D.F., Hungria M., Guimaraes C.T., Antonio R.V., Almeida F.C., de Almeida L.G.P., de Almeida R., Alves-Gomes J.A., Andrade E.M., Araripe J., de Araujo M.F.F., Astolfi-Filho S., Azevedo V., Baptista A.J., Bataus L.A.M., Batista J.S., Belo A. , van den Berg C., Bogo M., Bonatto S., Bordignon J., Brigido M.M., Brito C.A., Brocchi M., Burity H.A., Camargo A.A., Cardoso D.D.P., Carneiro N.P., Carraro D.M., Carvalho C.M.B., Cascardo J.C.M., Cavada B.S., Chueire L.M.O., Creczynski-Pasa T.B., Cunha-Junior N.C., Fagundes N., Falcao C.L., Fantinatti F., Farias I.P., Felipe M.S.S., Ferrari L.P., Ferro J.A., Ferro M.I.T., Franco G.R., Freitas N.S.A., Furlan L.R., Gazzinelli R.T., Gomes E.A., Goncalves P.R., Grangeiro T.B., Grattapaglia D., Grisard E.C., Hanna E.S., Jardim S.N., Laurino J., Leoi L.C.T., Lima L.F.A., Loureiro M.F., Lyra M.C.C.P., Madeira H.M.F., Manfio G.P., Maranhao A.Q., Martins W.S., di Mauro S.M.Z., de Medeiros S.R.B., Meissner R.V., Moreira M.A.M., Nascimento F.F., Nicolas M.F., Oliveira J.G., Oliveira S.C., Paixao R.F.C., Parente J.A., Pedrosa F.O., Pena S.D.J., Pereira J.O., Pereira M., Pinto L.S.R.C., Pinto L.S., Porto J.I.R., Potrich D.P., Ramalho-Neto C.E., Reis A.M.M., Rigo L.U., Rondinelli E., Santos E.B.P., Santos F.R., Schneider M.P.C., Seuanez H.N., Silva A.M.R., da Silva A.L.C., Silva D.W., Silva R., Simoes I.C., Simon D., Soares C.M.A., Soares R.B.A., Souza E.M., Souza K.R.L., Souza R.C., Steffens M.B.R., Steindel M., Teixeira S.R., Urmenyi T., Vettore A., Wassem R., Zaha A., Simpson A.J.G. Proc. Natl. Acad. Sci. U.S.A. 100:11660-11665(2003) [PubMed: 14500782] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 12472 / DSM 30191 / IFO 12614 / JCM 1249 / NCIB 9131.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AE016825 Genomic DNA. Translation: AAQ59767.1.
RefSeq	NP_901765.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	2548448.
GenomeReviews	Gene locus CV_2095 in contig AE016825_GR.
KEGG	cvi:CV_2095.
NMPDR	fig|243365.1.peg.2095.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q7NW95.
OMA	Q7NW95. WERYAMI.
Enzyme and pathway databases
BioCyc	CVIO243365:CV_2095-MON.
BRENDA	2.7.7.42. 415.
Family and domain databases
HAMAP	MF_00802. [Tree]
InterPro	IPR005190. GlnE. IPR013546. PII_UdlTrfase/GS_AdlTrfase. [Graphical view]
Pfam	PF08335. GlnD_UR_UTase. 1 hit. PF03710. GlnE. 2 hits. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

GLNE_CHRVO

Accession

Primary (citable) accession number: Q7NW95

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 4, 2005
Last sequence update:	December 15, 2003
Last modified:	June 16, 2009
This is version 32 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)